Page last updated: 2024-10-18

hydrogen and Spinal Cord Injuries

hydrogen has been researched along with Spinal Cord Injuries in 13 studies

Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.

Spinal Cord Injuries: Penetrating and non-penetrating injuries to the spinal cord resulting from traumatic external forces (e.g., WOUNDS, GUNSHOT; WHIPLASH INJURIES; etc.).

Research Excerpts

ExcerptRelevanceReference
"Nine patients were affected by tetraplegia and 15 by paraplegia."1.62Small intestinal bacterial overgrowth in spinal cord injury patients. ( Antuori, A; Mearin, F; Serra, J; Vallès, M, 2021)
"Hydrogen treatment could alleviate hyperpathia by autophagy-mediated NLRP3 inactivation."1.51Hydrogen-rich Saline Alleviated the Hyperpathia and Microglia Activation via Autophagy Mediated Inflammasome Inactivation in Neuropathic Pain Rats. ( Chen, H; Meng, X; Wang, Y; Xie, K; Yu, Y; Zhou, C, 2019)
"Hydrogen was administered to mice after spinal cord contusion injury was established for 42 days."1.48Inhalation of Hydrogen of Different Concentrations Ameliorates Spinal Cord Injury in Mice by Protecting Spinal Cord Neurons from Apoptosis, Oxidative Injury and Mitochondrial Structure Damages. ( Cao, L; Chen, X; Cui, J; Gu, Z; Ji, F; Pan, P; Su, J; Wang, Z; Weng, W; Zhai, X; Zhang, J; Zhi, X, 2018)
"We assess the deep vein thrombosis (DVT) and small intestinal bacterial overgrowth (SIBO) in SCI."1.46Association between small-intestinal bacterial overgrowth and deep vein thrombosis in patients with spinal cord injuries. ( Cheng, X; Lian, YJ; Xie, NC; Xu, HL; Zhang, L, 2017)
"Hydrogen has been deemed as a novel antioxidant."1.40Molecular hydrogen suppresses reactive astrogliosis related to oxidative injury during spinal cord injury in rats. ( Li, J; Li, XN; Liu, FT; Sun, XJ; Xiang, ZH; Xu, SM; Yuan, HB, 2014)
"Hydrogen-rich saline was injected intraperitoneally (5 ml/kg) immediately, and at 24 and 48 h after injury."1.36Hydrogen-rich saline protects against spinal cord injury in rats. ( Chen, C; Chen, Q; Mao, Y; Shi, X; Sun, X; Xia, C; Xu, S; Yuan, H; Zhang, JH, 2010)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19904 (30.77)18.7374
1990's1 (7.69)18.2507
2000's1 (7.69)29.6817
2010's6 (46.15)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Chen, H1
Zhou, C1
Xie, K1
Meng, X1
Wang, Y1
Yu, Y1
Vallès, M1
Antuori, A1
Mearin, F1
Serra, J1
Ge, L1
Wei, LH1
Du, CQ1
Song, GH1
Xue, YZ1
Shi, HS1
Yang, M1
Yin, XX1
Li, RT1
Wang, XE1
Wang, Z2
Song, WG1
Chen, X1
Cui, J1
Zhai, X1
Zhang, J1
Gu, Z1
Zhi, X1
Weng, W1
Pan, P1
Cao, L1
Ji, F1
Su, J1
Liu, FT1
Xu, SM1
Xiang, ZH1
Li, XN1
Li, J1
Yuan, HB1
Sun, XJ1
Cheng, X1
Zhang, L1
Xie, NC1
Xu, HL1
Lian, YJ1
Alexandrino, AP1
Rodrigues, MA1
Matsuo, T1
Schuquel, IT1
Costa, WF1
Santilli, JC1
Chen, C1
Chen, Q1
Mao, Y1
Xu, S1
Xia, C1
Shi, X1
Zhang, JH1
Yuan, H1
Sun, X1
Hayashi, N1
Tsubokawa, T1
Abe, K1
Green, BA1
Cawthon, DF1
Senter, HJ3
Stewart, WB1
Pilegaard, H1
Mohr, T1
Kjaer, M1
Juel, C1
Venes, JL2
Kauer, JS1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Adjuvant Therapy for Severe COPD Patients in the Stable Phase by an Oxyhydrogen Generator With Nebulizer: A Multi-centric, Randomized, Parallel-control and Double-blinded Clinic Study[NCT02850185]170 participants (Anticipated)Interventional2016-07-15Recruiting
A Multi-Center, Randomized, Controlled, Trial of Cerebrospinal Fluid Drainage (CSFD) in Acute Spinal Cord Injury[NCT02495545]15 participants (Actual)Interventional2015-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

13 other studies available for hydrogen and Spinal Cord Injuries

ArticleYear
Hydrogen-rich Saline Alleviated the Hyperpathia and Microglia Activation via Autophagy Mediated Inflammasome Inactivation in Neuropathic Pain Rats.
    Neuroscience, 2019, 11-21, Volume: 421

    Topics: Animals; Autophagy; Behavior Rating Scale; Calcium-Binding Proteins; CARD Signaling Adaptor Proteins

2019
Small intestinal bacterial overgrowth in spinal cord injury patients.
    Gastroenterologia y hepatologia, 2021, Volume: 44, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Aged; Blind Loop Syndrome; Breath Tests; Chronic Disease; Cross-Se

2021
Hydrogen-rich saline attenuates spinal cord hemisection-induced testicular injury in rats.
    Oncotarget, 2017, Jun-27, Volume: 8, Issue:26

    Topics: Animals; Apoptosis; Biomarkers; Disease Models, Animal; Gene Expression; Germ Cells; GTP Phosphohydr

2017
Inhalation of Hydrogen of Different Concentrations Ameliorates Spinal Cord Injury in Mice by Protecting Spinal Cord Neurons from Apoptosis, Oxidative Injury and Mitochondrial Structure Damages.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 47, Issue:1

    Topics: Administration, Inhalation; Animals; Apoptosis; Cells, Cultured; Female; Hydrogen; Mice; Mitochondri

2018
Molecular hydrogen suppresses reactive astrogliosis related to oxidative injury during spinal cord injury in rats.
    CNS neuroscience & therapeutics, 2014, Volume: 20, Issue:8

    Topics: Animals; Animals, Newborn; Astrocytes; Cell Proliferation; Cells, Cultured; Chlorides; Cytokines; En

2014
Association between small-intestinal bacterial overgrowth and deep vein thrombosis in patients with spinal cord injuries.
    Journal of thrombosis and haemostasis : JTH, 2017, Volume: 15, Issue:2

    Topics: Adult; Bacterial Infections; Body Mass Index; Breath Tests; Female; Gastrointestinal Diseases; Gluco

2017
Evaluation of seminal citrate level by 1H nuclear magnetic resonance spectroscopy in men with spinal cord injury.
    Spinal cord, 2009, Volume: 47, Issue:12

    Topics: Adult; Biomarkers; Citric Acid; Down-Regulation; Humans; Hydrogen; Magnetic Resonance Spectroscopy;

2009
Hydrogen-rich saline protects against spinal cord injury in rats.
    Neurochemical research, 2010, Volume: 35, Issue:7

    Topics: Animals; Antioxidants; Apoptosis; Brain-Derived Neurotrophic Factor; Caspases; Cell Death; Hindlimb;

2010
[Disturbances of hydrogen electron transport system and free radical reactions after severe spinal cord injury].
    No shinkei geka. Neurological surgery, 1984, Volume: 12, Issue:9

    Topics: Animals; Electron Transport; Energy Metabolism; Free Radicals; Hydrogen; Hydrogen-Ion Concentration;

1984
Comparison of hydrogen clearance and 14C-antipyrine autoradiography in the measurement of spinal cord blood flow after severe impact injury.
    Journal of neurosurgery, 1980, Volume: 52, Issue:6

    Topics: Animals; Antipyrine; Autoradiography; Blood Flow Velocity; Carbon Radioisotopes; Cats; Hydrogen; Met

1980
Lactate/H+ transport in skeletal muscle from spinal-cord-injured patients.
    Scandinavian journal of medicine & science in sports, 1998, Volume: 8, Issue:2

    Topics: Adult; Biopsy; Collagenases; Humans; Hydrogen; Ion Transport; Lactates; Male; Motor Activity; Muscle

1998
Loss of autoregulation and posttraumatic ischemia following experimental spinal cord trauma.
    Journal of neurosurgery, 1979, Volume: 50, Issue:2

    Topics: Animals; Cats; Homeostasis; Hydrogen; Ischemia; Regional Blood Flow; Spinal Cord; Spinal Cord Injuri

1979
Alteration of posttraumatic ischemia in experimental spinal cord trauma by a central nervous system depressant.
    Journal of neurosurgery, 1979, Volume: 50, Issue:2

    Topics: Animals; Cats; Central Nervous System Depressants; Hydrogen; Hydroxybutyrates; Ischemia; Regional Bl

1979