hydrogen has been researched along with Pulmonary Fibrosis in 5 studies
Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study investigated the effects of hydrogen-rich saline, a selective hydroxyl radical scavenger, on lipopolysaccharide (LPS)-induced pulmonary fibrosis." | 7.85 | Protective Effects of Hydrogen-Rich Saline Against Lipopolysaccharide-Induced Alveolar Epithelial-to-Mesenchymal Transition and Pulmonary Fibrosis. ( Dong, WW; Jiang, L; Liu, YJ; Mao, YF; Sun, XJ; Zhang, YQ; Zhu, XY, 2017) |
| " The present study investigated the effects of hydrogen-rich saline, a selective hydroxyl radical scavenger, on lipopolysaccharide (LPS)-induced pulmonary fibrosis." | 3.85 | Protective Effects of Hydrogen-Rich Saline Against Lipopolysaccharide-Induced Alveolar Epithelial-to-Mesenchymal Transition and Pulmonary Fibrosis. ( Dong, WW; Jiang, L; Liu, YJ; Mao, YF; Sun, XJ; Zhang, YQ; Zhu, XY, 2017) |
| "For example, coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global pandemic." | 1.72 | Molecular hydrogen is a promising therapeutic agent for pulmonary disease. ( Fu, Z; Zhang, J, 2022) |
| "Hydrogen water treatment significantly increased the expression of Nrf2 and promoted the production of the antioxidants in PQ-exposed lung fibroblasts." | 1.56 | [Hydrogen water alleviates paraquat-induced lung fibroblast injury ( Deng, S; Dong, Z; Lei, W; Li, T; Li, Z; Wu, W; Zhang, T, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fu, Z | 1 |
| Zhang, J | 1 |
| Gao, L | 1 |
| Jiang, D | 1 |
| Geng, J | 1 |
| Dong, R | 1 |
| Dai, H | 1 |
| Li, T | 1 |
| Deng, S | 1 |
| Lei, W | 1 |
| Li, Z | 1 |
| Wu, W | 1 |
| Zhang, T | 1 |
| Dong, Z | 1 |
| Dong, WW | 1 |
| Zhang, YQ | 1 |
| Zhu, XY | 1 |
| Mao, YF | 1 |
| Sun, XJ | 1 |
| Liu, YJ | 1 |
| Jiang, L | 1 |
| Terasaki, Y | 1 |
| Ohsawa, I | 1 |
| Terasaki, M | 1 |
| Takahashi, M | 1 |
| Kunugi, S | 1 |
| Dedong, K | 1 |
| Urushiyama, H | 1 |
| Amenomori, S | 1 |
| Kaneko-Togashi, M | 1 |
| Kuwahara, N | 1 |
| Ishikawa, A | 1 |
| Kamimura, N | 1 |
| Ohta, S | 1 |
| Fukuda, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Hydrogen Inhalation on Bronchiectasis (HYBRID): A Randomized, Multi-center, Double-blind, Parallel-group Study[NCT02765295] | 120 participants (Anticipated) | Interventional | 2016-06-01 | Recruiting | |||
| Adjuvant Therapy for Severe Asthma by an Oxyhydrogen Generator With Nebulizer: A Multi-centric, Randomized, Parallel-control and Double-blinded Clinic Study on Effectiveness and Safety[NCT02883582] | 150 participants (Anticipated) | Interventional | 2016-08-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 other studies available for hydrogen and Pulmonary Fibrosis
| Article | Year |
|---|---|
Molecular hydrogen is a promising therapeutic agent for pulmonary disease.
Topics: Acute Lung Injury; Aging; Animals; Anti-Inflammatory Agents; Antioxidants; Asthma; Autophagy; COVID- | 2022 |
Hydrogen inhalation attenuated bleomycin-induced pulmonary fibrosis by inhibiting transforming growth factor-β1 and relevant oxidative stress and epithelial-to-mesenchymal transition.
Topics: Administration, Inhalation; Animals; Bleomycin; Epithelial-Mesenchymal Transition; Hydrogen; Male; O | 2019 |
[Hydrogen water alleviates paraquat-induced lung fibroblast injury
Topics: Fibroblasts; Humans; Hydrogen; Lung; NF-E2-Related Factor 2; Paraquat; Pulmonary Fibrosis; Water | 2020 |
Protective Effects of Hydrogen-Rich Saline Against Lipopolysaccharide-Induced Alveolar Epithelial-to-Mesenchymal Transition and Pulmonary Fibrosis.
Topics: Animals; Cadherins; Collagen; Collagen Type I; Epithelial Cells; Epithelial-Mesenchymal Transition; | 2017 |
Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress.
Topics: Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Cell Line; Cell | 2011 |
Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress.
Topics: Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Cell Line; Cell | 2011 |
Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress.
Topics: Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Cell Line; Cell | 2011 |
Hydrogen therapy attenuates irradiation-induced lung damage by reducing oxidative stress.
Topics: Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Cell Line; Cell | 2011 |