Page last updated: 2024-10-18

hydrogen and Nervous System Disorders

hydrogen has been researched along with Nervous System Disorders in 11 studies

Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.

Research Excerpts

ExcerptRelevanceReference
"Fundamental and clinical evidence supports the antioxidant, antiinflammation, antiapoptosis and mitochondrial protective effects of hydrogen in the pathophysiology of nervous system diseases."5.05Prospects of molecular hydrogen in perioperative neuroprotection from basic research to clinical application. ( Wang, G; Wang, Z; Xie, K, 2020)
"Five minutes after achieving ROSC, post-cardiac arrest rats were randomized into 4 groups: mechanically ventilated with 26% O2 and normothermia (control); mechanically ventilated with 26% O2, 1."1.40Hydrogen inhalation during normoxic resuscitation improves neurological outcome in a rat model of cardiac arrest independently of targeted temperature management. ( Fukuda, K; Hayashida, K; Hori, S; Kamimura, N; Ohta, S; Sano, M; Suzuki, M; Yokota, T, 2014)
"Hydrogen (H2) is a potent antioxidant shown to selectively reverse cytotoxic oxygen-radical injury in the brain."1.37Protective effect of hydrogen gas therapy after germinal matrix hemorrhage in neonatal rats. ( Fathali, N; Lekic, T; Manaenko, A; Peterson, M; Rolland, W; Tang, J; Zhang, JH, 2011)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's9 (81.82)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Wang, Z1
Wang, G1
Xie, K1
Ono, H1
Nishijima, Y1
Ohta, S3
Sakamoto, M1
Kinone, K1
Horikosi, T1
Tamaki, M1
Takeshita, H1
Futatuki, T1
Ohishi, W1
Ishiguro, T1
Okamoto, S1
Ishii, S1
Takanami, H1
Hayashida, K2
Sano, M2
Kamimura, N2
Yokota, T2
Suzuki, M2
Fukuda, K2
Hori, S2
Drabek, T1
Kochanek, PM1
Wu, MJ1
Zhang, YJ1
Yu, H1
Zhao, M1
Liu, MD1
Pu, YY1
Wang, D1
Xie, Y1
Xue, GC1
Jiang, Y1
Yang, QQ1
Sun, XJ1
Cao, L1
Hong, Y1
Chen, S1
Zhang, JM1
Manaenko, A2
Lekic, T2
Ma, Q1
Ostrowski, RP1
Zhang, JH2
Tang, J2
Rolland, W1
Fathali, N1
Peterson, M1
Skillman, JJ1
Gould, SA1
Chung, RS1
Silen, W1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Perioperative Hydrogen Inhalation on Post-operative Pain and Inflammation Cytokines[NCT05476575]32 participants (Anticipated)Interventional2021-10-28Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for hydrogen and Nervous System Disorders

ArticleYear
Prospects of molecular hydrogen in perioperative neuroprotection from basic research to clinical application.
    Current opinion in anaesthesiology, 2020, Volume: 33, Issue:5

    Topics: Humans; Hydrogen; Nervous System Diseases; Neuroprotection; Neuroprotective Agents; Perioperative Ca

2020
[Research advances on hydrogen therapy in nervous system diseases].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2010, Volume: 39, Issue:6

    Topics: Antioxidants; Humans; Hydrogen; Hydroxyl Radical; Nervous System; Nervous System Diseases; Oxidative

2010

Trials

1 trial available for hydrogen and Nervous System Disorders

ArticleYear
Hydrogen Gas Inhalation Treatment in Acute Cerebral Infarction: A Randomized Controlled Clinical Study on Safety and Neuroprotection.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2017, Volume: 26, Issue:11

    Topics: Administration, Inhalation; Aged; Aged, 80 and over; Blood Pressure; Cerebral Infarction; Diffusion

2017

Other Studies

8 other studies available for hydrogen and Nervous System Disorders

ArticleYear
Hydrogen inhalation during normoxic resuscitation improves neurological outcome in a rat model of cardiac arrest independently of targeted temperature management.
    Circulation, 2014, Dec-09, Volume: 130, Issue:24

    Topics: Administration, Inhalation; Animals; Blood Circulation; Body Temperature; Cerebral Cortex; Disease M

2014
Improving outcomes from resuscitation: from hypertension and hemodilution to therapeutic hypothermia to H2.
    Circulation, 2014, Dec-09, Volume: 130, Issue:24

    Topics: Animals; Body Temperature; Heart Arrest; Hydrogen; Male; Nervous System Diseases; Resuscitation

2014
Letter by Wu et al Regarding Article, "Hydrogen Inhalation During Normoxic Resuscitation Improves Neurological Outcome in a Rat Model of Cardiac Arrest Independently of Targeted Temperature Management".
    Circulation, 2015, Sep-15, Volume: 132, Issue:11

    Topics: Animals; Body Temperature; Heart Arrest; Hydrogen; Male; Nervous System Diseases; Resuscitation

2015
Response to Letter Regarding Article, "Hydrogen Inhalation During Normoxic Resuscitation Improves Neurological Outcome in a Rat Model of Cardiac Arrest Independently of Targeted Temperature Management".
    Circulation, 2015, Sep-15, Volume: 132, Issue:11

    Topics: Animals; Body Temperature; Heart Arrest; Hydrogen; Male; Nervous System Diseases; Resuscitation

2015
Hydrogen-rich water improves neurological functional recovery in experimental autoimmune encephalomyelitis mice.
    Journal of neuroimmunology, 2016, 05-15, Volume: 294

    Topics: Analysis of Variance; Animals; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug;

2016
Hydrogen inhalation is neuroprotective and improves functional outcomes in mice after intracerebral hemorrhage.
    Acta neurochirurgica. Supplement, 2011, Volume: 111

    Topics: Administration, Inhalation; Analysis of Variance; Animals; Brain; Brain Edema; Cerebral Hemorrhage;

2011
Protective effect of hydrogen gas therapy after germinal matrix hemorrhage in neonatal rats.
    Acta neurochirurgica. Supplement, 2011, Volume: 111

    Topics: Analysis of Variance; Animals; Animals, Newborn; Cerebral Hemorrhage; Cognition Disorders; Collagena

2011
The gastric mucosal barrier: clinical and experimental studies in critically ill and normal man, and in the rabbit.
    Annals of surgery, 1970, Volume: 172, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Aged; Animals; Biological Transport; Blood Transfusion; Female; Ga

1970