hydrogen has been researched along with Nerve Pain in 8 studies
Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the role of autophagy in hydrogen-rich saline attenuating post-herpetic neuralgia( PHN) in rats." | 7.85 | [Hydrogen-rich saline attenuates hyperalgesia and reduces cytokines in rats with post-herpetic neuralgia via activating autophagy]. ( Bian, Y; Chen, H; Dong, A; Ma, H; Wang, Y; Xie, K, 2017) |
| "To investigate the role of autophagy in hydrogen-rich saline attenuating post-herpetic neuralgia( PHN) in rats." | 3.85 | [Hydrogen-rich saline attenuates hyperalgesia and reduces cytokines in rats with post-herpetic neuralgia via activating autophagy]. ( Bian, Y; Chen, H; Dong, A; Ma, H; Wang, Y; Xie, K, 2017) |
| "In a rat model of neuropathic pain induced by L5 spinal nerve ligation (L5 SNL), intrathecal injection of hydrogen-rich normal saline relieved L5 SNL-induced mechanical allodynia and thermal hyperalgesia." | 3.80 | Intrathecal infusion of hydrogen-rich normal saline attenuates neuropathic pain via inhibition of activation of spinal astrocytes and microglia in rats. ( Ge, Y; Huang, S; Lu, Z; Sun, X; Sun, Y; Wu, F; Xiang, Z; Yang, L; Yu, WF, 2014) |
| "Hydrogen has a promising anti-neuroinflammatory impact." | 1.91 | Amelioration of nerve demyelination by hydrogen-producing silicon-based agent in neuropathic pain rats. ( Li, Q; Lu, B; Mu, G; Yu, X, 2023) |
| "Hydrogen treatment could alleviate hyperpathia by autophagy-mediated NLRP3 inactivation." | 1.51 | Hydrogen-rich Saline Alleviated the Hyperpathia and Microglia Activation via Autophagy Mediated Inflammasome Inactivation in Neuropathic Pain Rats. ( Chen, H; Meng, X; Wang, Y; Xie, K; Yu, Y; Zhou, C, 2019) |
| "Neuropathic pain is a chronic and intractable pain, with very few effective analgesics." | 1.48 | Hydrogen-Rich Saline Activated Autophagy via HIF-1 ( Chen, H; Huo, X; Li, B; Liu, J; Ma, W; Shi, K; Wang, H; Wang, X; Xie, K; Yu, Y, 2018) |
| "Hydrogen (H2) has anti-inflammation, anti-apoptosis, and anti-oxidative stress effects." | 1.42 | H2 Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain. ( Chen, H; Chen, Y; Li, Y; Liu, L; Wang, G; Xie, K; Yu, Y, 2015) |
| "When hydrogen was administered only for the maintenance phase (from day 4 to 21 after ligation), hyperalgesia but not allodynia was alleviated." | 1.40 | Molecular hydrogen attenuates neuropathic pain in mice. ( Kawaguchi, M; Kazama, T; Otsubo, Y; Satoh, Y, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (87.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Mu, G | 1 |
| Li, Q | 1 |
| Lu, B | 1 |
| Yu, X | 1 |
| Chen, H | 4 |
| Zhou, C | 1 |
| Xie, K | 4 |
| Meng, X | 1 |
| Wang, Y | 2 |
| Yu, Y | 3 |
| Ma, H | 1 |
| Dong, A | 1 |
| Bian, Y | 1 |
| Wang, H | 1 |
| Huo, X | 1 |
| Li, B | 1 |
| Liu, J | 1 |
| Ma, W | 1 |
| Wang, X | 1 |
| Shi, K | 1 |
| Chen, Q | 1 |
| Chen, P | 1 |
| Zhou, S | 1 |
| Yan, X | 1 |
| Zhang, J | 1 |
| Sun, X | 2 |
| Yuan, H | 1 |
| Yu, W | 1 |
| Ge, Y | 1 |
| Wu, F | 1 |
| Xiang, Z | 1 |
| Yang, L | 1 |
| Huang, S | 1 |
| Lu, Z | 1 |
| Sun, Y | 1 |
| Yu, WF | 1 |
| Kawaguchi, M | 1 |
| Satoh, Y | 1 |
| Otsubo, Y | 1 |
| Kazama, T | 1 |
| Chen, Y | 1 |
| Liu, L | 1 |
| Li, Y | 1 |
| Wang, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Perioperative Hydrogen Inhalation on Post-operative Pain and Inflammation Cytokines[NCT05476575] | 32 participants (Anticipated) | Interventional | 2021-10-28 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 other studies available for hydrogen and Nerve Pain
| Article | Year |
|---|---|
Amelioration of nerve demyelination by hydrogen-producing silicon-based agent in neuropathic pain rats.
Topics: Animals; Demyelinating Diseases; Hydrogen; Inflammasomes; Neuralgia; NLR Family, Pyrin Domain-Contai | 2023 |
Hydrogen-rich Saline Alleviated the Hyperpathia and Microglia Activation via Autophagy Mediated Inflammasome Inactivation in Neuropathic Pain Rats.
Topics: Animals; Autophagy; Behavior Rating Scale; Calcium-Binding Proteins; CARD Signaling Adaptor Proteins | 2019 |
[Hydrogen-rich saline attenuates hyperalgesia and reduces cytokines in rats with post-herpetic neuralgia via activating autophagy].
Topics: Animals; Autophagy; Hydrogen; Hyperalgesia; Interleukin-1beta; Interleukin-6; Male; Microtubule-Asso | 2017 |
Hydrogen-Rich Saline Activated Autophagy via HIF-1
Topics: Animals; Autophagy; Disease Models, Animal; Hydrogen; Hypoxia-Inducible Factor 1, alpha Subunit; Mal | 2018 |
Hydrogen-rich saline attenuated neuropathic pain by reducing oxidative stress.
Topics: Animals; Hydrogen; Neuralgia; Oxidative Stress; Rats, Sprague-Dawley; Spinal Cord | 2013 |
Intrathecal infusion of hydrogen-rich normal saline attenuates neuropathic pain via inhibition of activation of spinal astrocytes and microglia in rats.
Topics: Animals; Astrocytes; Cytokines; Gene Expression Regulation, Enzymologic; Hydrogen; Hydroxides; Hyper | 2014 |
Molecular hydrogen attenuates neuropathic pain in mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Analgesics; Animals; Antioxidants; Deoxyguanosine; Drinking | 2014 |
H2 Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain.
Topics: Animals; Carbon Monoxide; Cytokines; Disease Models, Animal; Heme Oxygenase-1; Hydrogen; Male; Neura | 2015 |