hydrogen has been researched along with MODS in 7 studies
Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The current study aims to outline the factors that predict in-hospital outcome and the need for intensive care unit (ICU) admission among the patients who presented with acute hydrogen cyanamide exposure as well as to evaluate the roles of the Multiple Organ Dysfunction Score (MODS) and the Sequential Organ Failure Assessment (SOFA) score as unfavorable outcome predictors." | 8.02 | Evaluation of Multiple Organ Dysfunction Score (MODS) and the Sequential Organ Failure Assessment (SOFA) score as in-hospital outcome predictors among cases of hydrogen cyanamide exposure: a cross-sectional study. ( Fayed, MM; Sharif, AF, 2021) |
| "These results suggest that PINK1-mediated mitophagy plays a key role in the protective effects of hydrogen against cell injury in LPS-induced inflammation and CLP-induced acute lung injury." | 8.02 | Hydrogen alleviates cell damage and acute lung injury in sepsis via PINK1/Parkin-mediated mitophagy. ( Chen, H; Dong, B; Lin, H; Wang, Y; Xie, K; Yu, Y, 2021) |
| "Hydrogen provided protection from organ injury induced by sepsis via autophagy activation and endoplasmic reticulum stress pathway inactivation." | 7.96 | Hydrogen alleviated organ injury and dysfunction in sepsis: The role of cross-talk between autophagy and endoplasmic reticulum stress: Experimental research. ( Chen, HG; Han, HZ; Li, Y; Xie, KL; Yu, YH, 2020) |
| "Pancreatitis is an inflammatory disease of the pancreas characterized by acinar cell injury and is associated with the abnormal release of trypsin, which results in high mortality due to systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS)." | 6.72 | Recent advances in studies of molecular hydrogen in the treatment of pancreatitis. ( Li, G; Li, Y; Suo, L; Zhang, J, 2021) |
| "Hydrogen has been reported to selectively reduce hydroxyl radicals and peroxynitrite anion in many pathologic processes." | 5.39 | Effects of hydrogen-rich saline treatment on polymicrobial sepsis. ( Fan, YX; Ji, MH; Li, GM; Li, N; Li, WY; Sun, XJ; Tian, M; Yang, JJ; Zeng, QT, 2013) |
| "Sepsis/multiple organ dysfunction syndrome is the leading cause of death in critically ill patients." | 5.36 | Hydrogen gas improves survival rate and organ damage in zymosan-induced generalized inflammation model. ( Hou, L; Liu, W; Pei, Y; Wang, G; Xie, K; Xiong, L; Yu, Y; Zhang, Z, 2010) |
| " The current study aims to outline the factors that predict in-hospital outcome and the need for intensive care unit (ICU) admission among the patients who presented with acute hydrogen cyanamide exposure as well as to evaluate the roles of the Multiple Organ Dysfunction Score (MODS) and the Sequential Organ Failure Assessment (SOFA) score as unfavorable outcome predictors." | 4.02 | Evaluation of Multiple Organ Dysfunction Score (MODS) and the Sequential Organ Failure Assessment (SOFA) score as in-hospital outcome predictors among cases of hydrogen cyanamide exposure: a cross-sectional study. ( Fayed, MM; Sharif, AF, 2021) |
| "These results suggest that PINK1-mediated mitophagy plays a key role in the protective effects of hydrogen against cell injury in LPS-induced inflammation and CLP-induced acute lung injury." | 4.02 | Hydrogen alleviates cell damage and acute lung injury in sepsis via PINK1/Parkin-mediated mitophagy. ( Chen, H; Dong, B; Lin, H; Wang, Y; Xie, K; Yu, Y, 2021) |
| "Hydrogen provided protection from organ injury induced by sepsis via autophagy activation and endoplasmic reticulum stress pathway inactivation." | 3.96 | Hydrogen alleviated organ injury and dysfunction in sepsis: The role of cross-talk between autophagy and endoplasmic reticulum stress: Experimental research. ( Chen, HG; Han, HZ; Li, Y; Xie, KL; Yu, YH, 2020) |
| "Pancreatitis is an inflammatory disease of the pancreas characterized by acinar cell injury and is associated with the abnormal release of trypsin, which results in high mortality due to systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS)." | 2.72 | Recent advances in studies of molecular hydrogen in the treatment of pancreatitis. ( Li, G; Li, Y; Suo, L; Zhang, J, 2021) |
| "Hydrogen has been reported to selectively reduce hydroxyl radicals and peroxynitrite anion in many pathologic processes." | 1.39 | Effects of hydrogen-rich saline treatment on polymicrobial sepsis. ( Fan, YX; Ji, MH; Li, GM; Li, N; Li, WY; Sun, XJ; Tian, M; Yang, JJ; Zeng, QT, 2013) |
| "Sepsis/multiple organ dysfunction syndrome is the leading cause of death in critically ill patients." | 1.36 | Hydrogen gas improves survival rate and organ damage in zymosan-induced generalized inflammation model. ( Hou, L; Liu, W; Pei, Y; Wang, G; Xie, K; Xiong, L; Yu, Y; Zhang, Z, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 4 (57.14) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, HG | 1 |
| Han, HZ | 1 |
| Li, Y | 2 |
| Yu, YH | 1 |
| Xie, KL | 1 |
| Li, G | 1 |
| Suo, L | 1 |
| Zhang, J | 1 |
| Sharif, AF | 1 |
| Fayed, MM | 1 |
| Chen, H | 1 |
| Lin, H | 1 |
| Dong, B | 1 |
| Wang, Y | 1 |
| Yu, Y | 2 |
| Xie, K | 2 |
| Zheng, Y | 1 |
| Zhu, D | 1 |
| Zhang, Z | 1 |
| Liu, W | 1 |
| Pei, Y | 1 |
| Xiong, L | 1 |
| Hou, L | 1 |
| Wang, G | 1 |
| Li, GM | 1 |
| Ji, MH | 1 |
| Sun, XJ | 1 |
| Zeng, QT | 1 |
| Tian, M | 1 |
| Fan, YX | 1 |
| Li, WY | 1 |
| Li, N | 1 |
| Yang, JJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Daily Intake of 0.5 L of Water Saturated With Molecular Hydrogen for 21 Days in COVID-19 Patients Treated in Ambulatory Care. Double-blind, Randomized, Comparative Study[NCT04716985] | 700 participants (Actual) | Interventional | 2021-01-22 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for hydrogen and MODS
| Article | Year |
|---|---|
Recent advances in studies of molecular hydrogen in the treatment of pancreatitis.
Topics: Animals; Antioxidants; Apoptosis; Autophagy; Cell Death; Endoplasmic Reticulum Stress; Humans; Hydro | 2021 |
Molecular Hydrogen Therapy Ameliorates Organ Damage Induced by Sepsis.
Topics: Animals; Humans; Hydrogen; Multiple Organ Failure; Organ Specificity; Oxidative Stress; Sepsis; Trea | 2016 |
5 other studies available for hydrogen and MODS
| Article | Year |
|---|---|
Hydrogen alleviated organ injury and dysfunction in sepsis: The role of cross-talk between autophagy and endoplasmic reticulum stress: Experimental research.
Topics: Animals; Autophagy; Disease Models, Animal; Drug Evaluation, Preclinical; Endoplasmic Reticulum Stre | 2020 |
Evaluation of Multiple Organ Dysfunction Score (MODS) and the Sequential Organ Failure Assessment (SOFA) score as in-hospital outcome predictors among cases of hydrogen cyanamide exposure: a cross-sectional study.
Topics: Adolescent; Adult; Cross-Sectional Studies; Cyanamide; Hospitals; Humans; Hydrogen; Male; Middle Age | 2021 |
Hydrogen alleviates cell damage and acute lung injury in sepsis via PINK1/Parkin-mediated mitophagy.
Topics: Acute Lung Injury; Animals; Autophagy; Cell Line; Hydrogen; Inflammation; Lipopolysaccharides; Lung; | 2021 |
Hydrogen gas improves survival rate and organ damage in zymosan-induced generalized inflammation model.
Topics: Administration, Inhalation; Animals; Antioxidants; Biomarkers; Cytokines; Dinoprost; Drug Evaluation | 2010 |
Effects of hydrogen-rich saline treatment on polymicrobial sepsis.
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Cecum; Coinfection; Hydrogen; Inflammation Mediators; | 2013 |