hydrogen has been researched along with Injury, Myocardial Reperfusion in 40 studies
Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydrogen gas is recently proven to have anti-oxidative and anti-inflammation effects on ischemia-reperfusion injury." | 8.31 | Controlled Release of Hydrogen-Carrying Perfluorocarbons for Ischemia Myocardium-Targeting ( A, R; Hong, X; Nie, C; Pan, S; Sun, X; Wang, B; Wang, H; Wang, J; Wu, L; Xi, S; Yang, W; Yu, M; Zhou, M; Zou, R, 2023) |
| "To explore the effects of hydrogen-rich saline on Akt/GSK3β signaling pathways and cardiac function during myocardial ischemia-reperfusion (I/R) in rats." | 7.81 | [Effects of hydrogen-rich saline on Akt/GSK3β signaling pathways and cardiac function during myocardial ischemia-reperfusion in rats]. ( Li, H; Li, J; Wang, B; Yue, L; Zhao, Y, 2015) |
| "To investigate the effects of hydrogen-rich saline on cardiomyocyte autophagy during myocardial ischemia-reperfusion in aged rats." | 7.81 | [Effect of hydrogen-rich saline on cardiomyocyte autophagy during myocardial ischemia-reperfusion in aged rats]. ( Liu, D; Pan, Z; Xu, H; Yu, H; Zhao, Y, 2015) |
| "To explore the effects of hydrogen-rich saline on endoplasmic reticulum stress during myocardial ischemia-reperfusion (I/R) in rats." | 7.80 | [Effects of hydrogen-rich saline on endoplasmic reticulum stress during myocardial ischemia-reperfusion in rats]. ( Li, H; Li, S; Liu, D; Suo, C; Tang, Y; Zhao, Y, 2014) |
| "Hydrogen gas is recently proven to have anti-oxidative and anti-inflammation effects on ischemia-reperfusion injury." | 4.31 | Controlled Release of Hydrogen-Carrying Perfluorocarbons for Ischemia Myocardium-Targeting ( A, R; Hong, X; Nie, C; Pan, S; Sun, X; Wang, B; Wang, H; Wang, J; Wu, L; Xi, S; Yang, W; Yu, M; Zhou, M; Zou, R, 2023) |
| "To explore the effects of hydrogen-rich saline on Akt/GSK3β signaling pathways and cardiac function during myocardial ischemia-reperfusion (I/R) in rats." | 3.81 | [Effects of hydrogen-rich saline on Akt/GSK3β signaling pathways and cardiac function during myocardial ischemia-reperfusion in rats]. ( Li, H; Li, J; Wang, B; Yue, L; Zhao, Y, 2015) |
| "To investigate the effects of hydrogen-rich saline on cardiomyocyte autophagy during myocardial ischemia-reperfusion in aged rats." | 3.81 | [Effect of hydrogen-rich saline on cardiomyocyte autophagy during myocardial ischemia-reperfusion in aged rats]. ( Liu, D; Pan, Z; Xu, H; Yu, H; Zhao, Y, 2015) |
| "To explore the effects of hydrogen-rich saline on endoplasmic reticulum stress during myocardial ischemia-reperfusion (I/R) in rats." | 3.80 | [Effects of hydrogen-rich saline on endoplasmic reticulum stress during myocardial ischemia-reperfusion in rats]. ( Li, H; Li, S; Liu, D; Suo, C; Tang, Y; Zhao, Y, 2014) |
| "The inhibition of Na(+)-H+ exchange (NHE) with amiloride analogues in vitro has been shown to prevent reperfusion arrhythmias and additional cell necrosis." | 3.69 | Role of Na(+)-H+ exchange on reperfusion related myocardial injury and arrhythmias in an open-chest swine model. ( Fukuta, M; Iwa, T; Kobayashi, T; Uesugi, M; Wakida, Y, 1996) |
| "Hydrogen has been shown to have a certain therapeutic effect on MIRI, which can provide a new therapeutic direction for the clinical treatment of myocardial ischemia-reperfusion injury." | 2.66 | Protective Mechanism and Clinical Application of Hydrogen in Myocardial Ischemia-reperfusion Injury. ( Li, L; Li, X; Liu, F; Liu, L; Zhang, Z; Zhou, Y, 2020) |
| "Hydrogen‑rich saline was administered twice through intraperitoneal injection at a daily dose of 10 ml/kg following the operation in the in vivo model, and hydrogen‑rich medium culture was used for cells instead of normal medium in vitro." | 1.51 | Hydrogen-rich saline alleviates inflammation and apoptosis in myocardial I/R injury via PINK-mediated autophagy. ( Chen, H; Wu, Q; Xie, K; Yao, L, 2019) |
| "Hydrogen has been shown to exert a bioactive effect on the myocardium." | 1.51 | Attenuation of Cardiac Ischaemia-reperfusion Injury by Treatment with Hydrogen-rich Water. ( Geng, YJ; Li, L; Li, X; Li, Z; Liu, F; Liu, X; Sun, X; Wu, J; Zhou, Y, 2019) |
| "Hydrogen treatment alone significantly reduced malondialdehyde levels and serum high-mobility group box 1 protein levels as compared with air-treated controls." | 1.36 | Amelioration of rat cardiac cold ischemia/reperfusion injury with inhaled hydrogen or carbon monoxide, or both. ( Billiar, TR; Buchholz, BM; Cardinal, JS; Kaczorowski, DJ; Lee, S; McCurry, KR; Nakao, A; Sugimoto, R; Tobita, K; Toyoda, Y; Wang, Y, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (27.50) | 18.2507 |
| 2000's | 6 (15.00) | 29.6817 |
| 2010's | 17 (42.50) | 24.3611 |
| 2020's | 6 (15.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nie, C | 3 |
| A, R | 2 |
| Wang, J | 1 |
| Pan, S | 2 |
| Zou, R | 1 |
| Wang, B | 2 |
| Xi, S | 1 |
| Hong, X | 1 |
| Zhou, M | 1 |
| Wang, H | 2 |
| Yu, M | 1 |
| Wu, L | 1 |
| Sun, X | 4 |
| Yang, W | 5 |
| Yao, L | 1 |
| Chen, H | 1 |
| Wu, Q | 1 |
| Xie, K | 1 |
| Li, L | 6 |
| Liu, T | 4 |
| Li, X | 5 |
| Liu, X | 3 |
| Liu, L | 5 |
| Li, S | 5 |
| Li, Z | 3 |
| Zhou, Y | 6 |
| Liu, F | 6 |
| Zhang, Z | 5 |
| Liu, S | 2 |
| Zhang, R | 2 |
| Ding, X | 1 |
| Zheng, M | 1 |
| Yang, H | 2 |
| Du, H | 1 |
| Hong, Z | 1 |
| Lv, Y | 1 |
| Gao, Y | 2 |
| He, Y | 1 |
| Zhang, B | 1 |
| Chen, Y | 2 |
| Jin, Q | 1 |
| Wu, J | 2 |
| Yan, F | 1 |
| Zheng, H | 1 |
| Chi, J | 1 |
| Xu, Q | 1 |
| Zhao, L | 1 |
| Liu, W | 3 |
| Chen, O | 1 |
| Cao, Z | 1 |
| Li, H | 3 |
| Ye, Z | 1 |
| Zhang, N | 1 |
| Huang, J | 1 |
| Zhang, T | 2 |
| Wang, L | 1 |
| Han, L | 1 |
| Song, D | 1 |
| Diao, Y | 1 |
| Sun, Y | 2 |
| Gao, G | 1 |
| Chen, K | 1 |
| Pei, L | 1 |
| Geng, YJ | 1 |
| Shinbo, T | 1 |
| Kokubo, K | 1 |
| Sato, Y | 2 |
| Hagiri, S | 1 |
| Hataishi, R | 1 |
| Hirose, M | 1 |
| Kobayashi, H | 1 |
| Zhao, Y | 3 |
| Tang, Y | 1 |
| Suo, C | 1 |
| Liu, D | 2 |
| Zhang, G | 1 |
| Gao, S | 1 |
| Zhang, L | 1 |
| Tan, H | 1 |
| Xu, L | 1 |
| Geng, Y | 1 |
| Lin, Y | 1 |
| Aertker, B | 1 |
| Yue, L | 1 |
| Li, J | 1 |
| Pan, Z | 1 |
| Yu, H | 1 |
| Xu, H | 1 |
| Hayashida, K | 1 |
| Sano, M | 2 |
| Ohsawa, I | 1 |
| Shinmura, K | 1 |
| Tamaki, K | 1 |
| Kimura, K | 1 |
| Endo, J | 1 |
| Katayama, T | 1 |
| Kawamura, A | 1 |
| Kohsaka, S | 1 |
| Makino, S | 1 |
| Ohta, S | 1 |
| Ogawa, S | 1 |
| Fukuda, K | 1 |
| Sun, Q | 1 |
| Kang, Z | 1 |
| Cai, J | 1 |
| Liu, Y | 1 |
| Zhang, JH | 1 |
| Denoble, PJ | 1 |
| Tao, H | 1 |
| Nakao, A | 1 |
| Kaczorowski, DJ | 1 |
| Wang, Y | 1 |
| Cardinal, JS | 1 |
| Buchholz, BM | 1 |
| Sugimoto, R | 1 |
| Tobita, K | 1 |
| Lee, S | 1 |
| Toyoda, Y | 1 |
| Billiar, TR | 1 |
| McCurry, KR | 1 |
| Schibilsky, D | 1 |
| Beyersdorf, F | 1 |
| Goebel, U | 1 |
| Sakai, K | 1 |
| Cho, S | 1 |
| Shibata, I | 1 |
| Yoshitomi, O | 1 |
| Maekawa, T | 1 |
| Sumikawa, K | 1 |
| Yoshida, A | 1 |
| Asanuma, H | 1 |
| Sasaki, H | 1 |
| Sanada, S | 1 |
| Yamazaki, S | 1 |
| Asano, Y | 1 |
| Shinozaki, Y | 1 |
| Mori, H | 1 |
| Shimouchi, A | 1 |
| Asakura, M | 1 |
| Minamino, T | 1 |
| Takashima, S | 1 |
| Sugimachi, M | 1 |
| Mochizuki, N | 1 |
| Kitakaze, M | 1 |
| Tiefenbacher, CP | 1 |
| Kapitza, J | 1 |
| Dietz, V | 1 |
| Lee, CH | 1 |
| Niroomand, F | 1 |
| van Borren, MM | 1 |
| Baartscheer, A | 1 |
| Wilders, R | 1 |
| Ravesloot, JH | 1 |
| Barba, I | 1 |
| Jaimez-Auguets, E | 1 |
| Rodriguez-Sinovas, A | 1 |
| Garcia-Dorado, D | 1 |
| Karmazyn, M | 1 |
| Ray, M | 1 |
| Haist, JV | 1 |
| Liu, B | 1 |
| el Alaoui-Talibi, Z | 1 |
| Clanachan, AS | 1 |
| Schulz, R | 1 |
| Lopaschuk, GD | 1 |
| Fukuta, M | 1 |
| Wakida, Y | 1 |
| Iwa, T | 1 |
| Uesugi, M | 1 |
| Kobayashi, T | 1 |
| Fliegel, L | 1 |
| Liu, H | 1 |
| Cala, PM | 1 |
| Anderson, SE | 1 |
| Portman, MA | 1 |
| Panos, AL | 1 |
| Xiao, Y | 1 |
| Anderson, DL | 1 |
| Alfieris, GM | 1 |
| Ning, XH | 1 |
| Lupinetti, FM | 1 |
| Semplicini, A | 1 |
| Monari, A | 1 |
| Ito, K | 1 |
| Kagaya, Y | 1 |
| Ishizuka, T | 1 |
| Ito, N | 2 |
| Ishide, N | 1 |
| Shirato, K | 1 |
| Toda, H | 1 |
| Noguchi, T | 1 |
| Miyagishi, A | 1 |
| Umekawa, K | 1 |
| Kitano, M | 1 |
| Ohashi, N | 1 |
| Baron, O | 1 |
| Saiki, Y | 1 |
| Rebeyka, IM | 1 |
| Yamazaki, N | 1 |
| Zhao, TC | 1 |
| Shi, AY | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Metabolomic Profile of Patients Undergoing Myocardial Perfusion SPECT[NCT02968771] | 500 participants (Anticipated) | Observational | 2016-11-30 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for hydrogen and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Protective Mechanism and Clinical Application of Hydrogen in Myocardial Ischemia-reperfusion Injury.
Topics: Animals; Antioxidants; Calcium; Cardiovascular Diseases; Free Radicals; Humans; Hydrogen; Mice; Myoc | 2020 |
Regulation of the Na+/H+ exchanger in the mammalian myocardium.
Topics: Adrenergic alpha-Agonists; Animals; Catecholamines; Cell Differentiation; Gene Expression Regulation | 1997 |
[Sodium-hydrogen exchange and reperfusion myocardial injury: possible pathogenetic role and therapeutic implications].
Topics: Calcium; Humans; Hydrogen; Hydrogen-Ion Concentration; Myocardial Reperfusion Injury; Sodium; Sodium | 1997 |
37 other studies available for hydrogen and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Controlled Release of Hydrogen-Carrying Perfluorocarbons for Ischemia Myocardium-Targeting
Topics: Animals; Delayed-Action Preparations; Fluorocarbons; Hydrogen; Ischemia; Magnetic Resonance Imaging; | 2023 |
Hydrogen-rich saline alleviates inflammation and apoptosis in myocardial I/R injury via PINK-mediated autophagy.
Topics: Animals; Apoptosis; Autophagy; Biomarkers; Cytokines; Disease Models, Animal; Gene Silencing; Hydrog | 2019 |
Protein chip and bioinformatic analyses of differentially expressed proteins involved in the effect of hydrogen-rich water on myocardial ischemia-reperfusion injury.
Topics: Animals; Cluster Analysis; Computational Biology; Gene Ontology; Hydrogen; Male; Myocardial Reperfus | 2019 |
Effects of Hydrogen-rich Water on the PI3K/AKT Signaling Pathway in Rats with Myocardial Ischemia-reperfusion Injury.
Topics: Animals; Apoptosis; Caspase 3; Heart; Hydrogen; Male; Myocardial Reperfusion Injury; Phosphatidylino | 2020 |
Effect of hydrogen-rich water on the Nrf2/ARE signaling pathway in rats with myocardial ischemia-reperfusion injury.
Topics: Animals; Disease Models, Animal; Humans; Hydrogen; Male; Myocardial Reperfusion Injury; NF-E2-Relate | 2019 |
Metabolomics Analysis of the Effect of Hydrogen-Rich Water on Myocardial Ischemia-Reperfusion Injury in Rats.
Topics: Animals; Hydrogen; Male; Metabolomics; Myocardial Reperfusion Injury; Rats; Signal Transduction; Wat | 2020 |
Hydrogen gas inhalation alleviates myocardial ischemia-reperfusion injury by the inhibition of oxidative stress and NLRP3-mediated pyroptosis in rats.
Topics: Administration, Inhalation; Animals; Cell Survival; Hydrogen; Inflammasomes; Male; Myocardial Infarc | 2021 |
Hydrogen Attenuates Myocardial Injury in Rats by Regulating Oxidative Stress and NLRP3 Inflammasome Mediated Pyroptosis.
Topics: Administration, Inhalation; Animals; Antioxidants; Disease Models, Animal; Echocardiography; Humans; | 2021 |
Image-Guided Hydrogen Gas Delivery for Protection from Myocardial Ischemia-Reperfusion Injury via Microbubbles.
Topics: Animals; Hydrogen; Microbubbles; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Rats; | 2017 |
Hydrogen Gas Attenuates Myocardial Ischemia Reperfusion Injury Independent of Postconditioning in Rats by Attenuating Endoplasmic Reticulum Stress-Induced Autophagy.
Topics: Animals; Autophagy; Endoplasmic Reticulum Stress; Hydrogen; Ischemic Postconditioning; Male; Myocard | 2017 |
High-concentration hydrogen protects mouse heart against ischemia/reperfusion injury through activation of thePI3K/Akt1 pathway.
Topics: Animals; Cardiotonic Agents; Hydrogen; Mice, Inbred C57BL; Myocardial Reperfusion Injury; Phosphatid | 2017 |
Hydrogen‑rich solution against myocardial injury and aquaporin expression via the PI3K/Akt signaling pathway during cardiopulmonary bypass in rats.
Topics: Animals; Aquaporin 1; Aquaporin 4; Cardiopulmonary Bypass; Gene Expression Regulation; Hydrogen; Mal | 2018 |
Attenuation of Cardiac Ischaemia-reperfusion Injury by Treatment with Hydrogen-rich Water.
Topics: Animals; Apoptosis; Biomarkers; Cell Membrane; Computational Biology; Disease Models, Animal; Gene E | 2019 |
Breathing nitric oxide plus hydrogen gas reduces ischemia-reperfusion injury and nitrotyrosine production in murine heart.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Inhalation; Aldehydes; Animals; Antioxidants; Cardioton | 2013 |
[Effects of hydrogen-rich saline on endoplasmic reticulum stress during myocardial ischemia-reperfusion in rats].
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 12; Endoplasmic Reticulum Stress; Hydrogen; | 2014 |
Pharmacological postconditioning with lactic acid and hydrogen rich saline alleviates myocardial reperfusion injury in rats.
Topics: Animals; Apoptosis; Caspase 8; Disease Models, Animal; Female; Hydrogen; Ischemic Postconditioning; | 2015 |
[Effects of hydrogen-rich saline on Akt/GSK3β signaling pathways and cardiac function during myocardial ischemia-reperfusion in rats].
Topics: Animals; Cardiovascular Physiological Phenomena; Coronary Artery Disease; Glycogen Synthase Kinase 3 | 2015 |
[Effect of hydrogen-rich saline on cardiomyocyte autophagy during myocardial ischemia-reperfusion in aged rats].
Topics: Aging; Animals; Autophagy; Disease Models, Animal; Hydrogen; Ischemia; Male; Myocardial Reperfusion | 2015 |
Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia-reperfusion injury.
Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Hydrogen; Inhalation; Male; Myocardial Infarcti | 2008 |
Hydrogen-rich saline protects myocardium against ischemia/reperfusion injury in rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Apoptosis; Blood Pressure; Cardiotonic Agents; Caspase 3; Deox | 2009 |
Amelioration of rat cardiac cold ischemia/reperfusion injury with inhaled hydrogen or carbon monoxide, or both.
Topics: Administration, Inhalation; Animals; Apoptosis; Blotting, Western; Carbon Monoxide; Cold Ischemia; D | 2010 |
Re: Amelioration of rat cardiac cold ischemia/reperfusion injury with inhaled hydrogen or carbon monoxide, or both.
Topics: Administration, Inhalation; Animals; Apoptosis; Carbon Monoxide; Cold Ischemia; Drug Therapy, Combin | 2010 |
Inhalation of hydrogen gas protects against myocardial stunning and infarction in swine.
Topics: Administration, Inhalation; Animals; Cardiotonic Agents; Disease Models, Animal; Female; Gases; Hydr | 2012 |
H(2) mediates cardioprotection via involvements of K(ATP) channels and permeability transition pores of mitochondria in dogs.
Topics: Animals; Apoptosis; Cardiotonic Agents; Decanoic Acids; Dogs; Hydrogen; Hydroxy Acids; In Situ Nick- | 2012 |
Reduction of myocardial infarct size by fluvastatin.
Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Vessels; Cyclic GMP; Echocardiography, Doppl | 2003 |
NHE-1 and NBC during pseudo-ischemia/reperfusion in rabbit ventricular myocytes.
Topics: Animals; Heart Ventricles; Hydrogen; In Vitro Techniques; Myocardial Reperfusion Injury; Myocytes, C | 2004 |
1H NMR-based metabolomic identification of at-risk areas after myocardial infarction in swine.
Topics: Animals; Disease Models, Animal; Hydrogen; Lipid Metabolism; Magnetic Resonance Spectroscopy; Metabo | 2007 |
Comparative effects of Na+/H+ exchange inhibitors against cardiac injury produced by ischemia/reperfusion, hypoxia/reoxygenation, and the calcium paradox.
Topics: Adenosine Triphosphate; Amiloride; Animals; Bepridil; Calcium; Carrier Proteins; Glycogen; Heart; He | 1993 |
Uncoupling of contractile function from mitochondrial TCA cycle activity and MVO2 during reperfusion of ischemic hearts.
Topics: Adenosine Triphosphate; Animals; Citric Acid Cycle; Dichloroacetic Acid; Glucose; Heart; Hydrogen; I | 1996 |
Role of Na(+)-H+ exchange on reperfusion related myocardial injury and arrhythmias in an open-chest swine model.
Topics: Action Potentials; Amiloride; Animals; Arrhythmias, Cardiac; Calcium; Cardiac Pacing, Artificial; Co | 1996 |
Ethylisopropylamiloride diminishes changes in intracellular Na, Ca and pH in ischemic newborn myocardium.
Topics: Adenosine Triphosphate; Age Factors; Amiloride; Animals; Animals, Newborn; Anti-Arrhythmia Agents; C | 1997 |
Influence of the pH of cardioplegic solutions on cellular energy metabolism and hydrogen ion flux during neonatal hypothermic circulatory arrest and reperfusion: a dynamic 31P nuclear magnetic resonance study in a pig model.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Cardioplegic Solutions; Energy Metabolism; Heart | 1997 |
Diacylglycerol delays pH(i) overshoot after reperfusion and attenuates contracture in isolated, paced myocytes.
Topics: Alkaloids; Animals; Benzophenanthridines; Calcium; Cardiac Pacing, Artificial; Cell Separation; Diac | 1999 |
Cardioprotection of SM-15681, an Na+/H+ exchange inhibitor in ischemic and hypoxic isolated perfused rat hearts.
Topics: Amides; Amiloride; Animals; Anti-Arrhythmia Agents; Hydrogen; Indoles; Ion Transport; Myocardial Isc | 1999 |
pH paradox and neonatal heart.
Topics: Acidosis; Amiloride; Animals; Animals, Newborn; Blood Pressure; Calcium; Diastole; Female; Heart Arr | 2001 |
[Myocardial perfusion injury].
Topics: Animals; Arrhythmias, Cardiac; Calcium; Free Radicals; Humans; Hydrogen; Myocardial Reperfusion Inju | 1992 |
[The relationship between Na overload and Na/H exchange--a study in the isolated isovolumic rat hearts].
Topics: Animals; Hydrogen; In Vitro Techniques; Ion Transport; Male; Myocardial Reperfusion Injury; Myocardi | 1992 |