hydrogen has been researched along with Injury, Ischemia-Reperfusion in 96 studies
Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.
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" A recent study provided evidence that hydrogen inhalation exerted antioxidant and anti-apoptotic effects and protected the brain against ischemia-reperfusion injury by selectively reducing hydroxyl radical and peroxynitrite." | 8.86 | Hydrogen as a novel and effective treatment of acute carbon monoxide poisoning. ( Cai, J; He, J; Huo, Z; Shen, M; Sun, Q; Sun, X, 2010) |
"The increase in extracellular glutamate induced by spinal ischemia was significantly suppressed by 3% hydrogen gas inhalation (P < ." | 8.12 | Protective effects of hydrogen gas against spinal cord ischemia-reperfusion injury. ( Fujimoto, Y; Funao, T; Kimura, A; Mori, T; Mukai, A; Suehiro, K; Yamada, T, 2022) |
"Hydrogen treatment could potentially be a future therapeutic strategy for ischemia and its derived neurodegenerative diseases by improving cognitive abilities and inducing antioxidative and antiapoptotic effects." | 8.02 | Hydrogen-Rich Water Improves Cognitive Ability and Induces Antioxidative, Antiapoptotic, and Anti-Inflammatory Effects in an Acute Ischemia-Reperfusion Injury Mouse Model. ( Choi, JI; Lee, D, 2021) |
"Taken together, these results revealed the protective effect of hydrogen gas on hind limb ischemia reperfusion injury on mice by attenuating oxidative stress, impairing ER stress and apoptosis, and its ability to modulate JNK signaling pathway." | 8.02 | Protective Effect of Hydrogen Gas on Mouse Hind Limb Ischemia-Reperfusion Injury. ( Liu, J; Mei, X; Meng, J; Tong, J; Yu, P; Zhang, Y, 2021) |
"To investigate the effects of hydrogen-rich saline (HRS) on intestinal epithelial tight junction (TJ) barrier in rats with intestinal ischemia-reperfusion injury (IIRI)." | 7.96 | Hydrogen-rich saline protects intestinal epithelial tight junction barrier in rats with intestinal ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress-induced apoptosis pathway. ( Cheng, F; Ding, G; Fan, Q; Fu, T; Geng, L; Jiang, S; Li, Z; Xu, M, 2020) |
"Forty-five adult male Sprague Dawley rats (body weight 220-250 g) were randomly divided into three groups: (1) Sham operation group (SH), (2) Ischemia-reperfusion injury group (IR), and (3) Ischemia-reperfusion injury with preconditioning hydrogen group (PRH)." | 7.91 | Preconditioning with one-time hydrogen gas does not attenuate skin flap ischemia-reperfusion injury in rat models. ( Dong, X; Hao, Y; Liu, H; Wang, Y, 2019) |
" Hydrogen gas provides potent anti-inflammatory and antioxidant effects against ischemia-reperfusion injury (IRI)." | 7.91 | Protective effects of hydrogen inhalation during the warm ischemia phase against lung ischemia-reperfusion injury in rat donors after cardiac death. ( Deng, L; Li, W; Liu, J; Meng, C; Zhang, J; Zhou, H, 2019) |
" The hypothesis of this study is that hydrogen-rich solution could attenuateacute lung injury and improve mortality via chemerin and NLRP3 after LI/R in rats." | 7.91 | Hydrogen-Rich Saline Attenuates Acute Lung Injury Induced by Limb Ischemia/Reperfusion via Down-Regulating Chemerin and NLRP3 in Rats. ( Chen, Y; Du, J; Fan, X; Liu, KX; Wang, MH; Wang, XB; Yang, B; Zhou, J; Zou, R, 2019) |
"Anti-oxidant effects of hydrogen have been reported in studies examining ischaemia-reperfusion injury (IRI)." | 7.85 | Immersing lungs in hydrogen-rich saline attenuates lung ischaemia-reperfusion injury. ( Aoyama, A; Chen-Yoshikawa, TF; Date, H; Hijiya, K; Kondo, T; Miyamoto, E; Motoyama, H; Ohata, K; Saito, M; Takahashi, M; Tanaka, S, 2017) |
"Lung ischemia-reperfusion injury (IRI) may be attenuated through carbon monoxide (CO)'s anti-inflammatory effect or hydrogen (H2)'s anti-oxidant effect." | 7.83 | Protection of donor lung inflation in the setting of cold ischemia against ischemia-reperfusion injury with carbon monoxide, hydrogen, or both in rats. ( Cui, X; Jiang, C; Kang, J; Liu, J; Liu, R; Ma, L; Meng, C; Niu, L; Xing, J; Zhou, H, 2016) |
"Hydrogen significantly alleviated brain tissue histological damage, promoted HO-1 expression, upregulated levels of SOD, and decreased the levels of MDA in brain tissue after the ischemia reperfusion injury." | 7.83 | The protective effects of hydrogen on HO-1 expression in the brainafter focal cerebral ischemia reperfusion in rats. ( Liu, T; Wang, X; Zhang, L; Zhao, W, 2016) |
"Luminal injection of hydrogen-rich solution can reduce oxidative stress and consequently ameliorate ischemic-reperfusion injury." | 7.81 | Luminal injection of hydrogen-rich solution attenuates intestinal ischemia-reperfusion injury in rats. ( Cai, S; Kasahara, M; Kurokawa, R; Li, XK; Liu, C; Nakazawa, A; Sakamoto, S; Shigeta, T; Uemoto, S, 2015) |
"To investigate the role of FOXO3a in process of hydrogen-rich saline attenuating global cerebral ischemia-reperfusion (I/R) injury in rats." | 7.81 | [Role of FOXO3a in process of hydrogen-rich saline attenuating global cerebral ischemia-reperfusion injury in rats]. ( Chen, X; Dai, Q; Duan, M; Gao, Y; Wu, L; Xu, J; Yu, P; Zhang, L; Zhao, L, 2015) |
"The results indicate that hydrogen-rich saline could ameliorate ischemia/reperfusion injury and improve flap survival rate by inhibiting the apoptosis factor and, at the same time, promoting the expression of anti-apoptosis factor." | 7.81 | Hydrogen-rich saline attenuates skin ischemia/reperfusion induced apoptosis via regulating Bax/Bcl-2 ratio and ASK-1/JNK pathway. ( Cheng, AX; Li, JL; Liu, YF; Liu, YQ; Ma, XM; Wang, TT; Wang, YB; Xiao, YD; Xie, F; Zhang, MZ; Zhang, X; Zhao, PX, 2015) |
"Inhalation of hydrogen could attenuate renal ischemic/reperfusion injury in rats by decreasing the content of MDA." | 7.80 | [Protective effects of hydrogen on renal ischemia/reperfusion injury in rats]. ( Chen, XJ; Huang, H; Huang, W; Jiang, XQ; Zeng, K, 2014) |
"These results suggest that, in our model, hydrogen enriched saline treatment is protective against liver ischemia-reperfusion injury." | 7.80 | Protective effects of hydrogen enriched saline on liver ischemia reperfusion injury by reducing oxidative stress and HMGB1 release. ( Irwin, MG; Liu, Y; Lloyd, DM; Ma, D; Sun, X; Tao, K; Vizcaychipi, MP; Yang, L; Yu, W, 2014) |
"Molecular hydrogen has been proven effective in ameliorating cerebral ischemia/reperfusion (I/R) injury by selectively neutralizing reactive oxygen species." | 7.79 | Lactulose ameliorates cerebral ischemia-reperfusion injury in rats by inducing hydrogen by activating Nrf2 expression. ( Bi, H; Chen, X; Kang, Z; Li, M; Liu, W; Shi, D; Shi, J; Sun, X; Wang, Q; Ye, Z; Zhai, X, 2013) |
"Results provide a biochemical and histopathological basis for the action of hydrogen rich saline solution as a therapeutic agent for testicular damage induced by ischemia/reperfusion injury." | 7.78 | Protective effects of hydrogen rich saline solution on experimental testicular ischemia-reperfusion injury in rats. ( Jiang, D; Li, Z; Sun, X; Wu, D; Xu, B; Zhang, Y, 2012) |
"This study evaluated whether 2% hydrogen (H(2)) gas therapy protects against testicular ischemia/reperfusion injury which results in increased formation of reactive oxygen species and/or reactive nitrogen species, leading to testicular apoptosis and impaired spermatogenesis." | 7.78 | Inhaled hydrogen gas therapy for prevention of testicular ischemia/reperfusion injury in rats. ( Cho, YJ; Han, JS; Kim, JI; Lee, DH; Lee, JW; Lee, YA; Song, CS, 2012) |
"Inhalation of hydrogen gas has been proved to be an effective treatment for ischemia-reperfusion injury." | 7.76 | Oral administration of mannitol may be an effective treatment for ischemia-reperfusion injury. ( Liu, S; Sun, Q; Sun, X; Tao, H, 2010) |
"Pancreatitis is an inflammatory disease of the pancreas characterized by acinar cell injury and is associated with the abnormal release of trypsin, which results in high mortality due to systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS)." | 6.72 | Recent advances in studies of molecular hydrogen in the treatment of pancreatitis. ( Li, G; Li, Y; Suo, L; Zhang, J, 2021) |
"Intestinal volvulus can cause morbidity and mortality." | 5.72 | Protective Effects of Hydrogen-Rich Saline on Experimental Intestinal Volvulus in Rats. ( Dayanır, D; Karabulut, R; Karakaya, C; Kaya, C; Oral, H; Sonmez, K; Türkyılmaz, Z, 2022) |
"Hydrogen could inhibit the upregulation of autophagy in the present rodent model." | 5.62 | Hydrogen alleviates acute lung injury induced by limb ischaemia/reperfusion in mice. ( Liu, B; Liu, L; Qi, X; Qiu, T; Shen, X; Song, G; Yang, C, 2021) |
"In renal transplantation, ischemia reperfusion injury impairs early graft function and can reduce long term graft survival." | 5.48 | Hydrogen Gas Does Not Ameliorate Renal Ischemia Reperfusion Injury in a Preclinical Model. ( Adams, T; Hosgood, SA; Moore, T; Nicholson, ML; Qurashi, M, 2018) |
"Rat livers were harvested after 30-min cardiac arrest and stored for 4 h in University of Wisconsin solution." | 5.48 | Post-reperfusion hydrogen gas treatment ameliorates ischemia reperfusion injury in rat livers from donors after cardiac death: a preliminary study. ( Fujiyoshi, M; Fujiyoshi, S; Fukai, M; Hayasaka, T; Ishikawa, T; Kawamura, N; Kimura, T; Kobayashi, N; Shibata, K; Shimada, S; Shimamura, T; Taketomi, A; Umemoto, K, 2018) |
"Ischemia-reperfusion injury is one of the leading causes of tissue damage and dysfunction, in particular, free tissue transfer, traumatically amputated extremity, and prolonged tourniquet application during extremity surgery." | 5.46 | Protective Effect of Hydrogen Gas Inhalation on Muscular Damage Using a Mouse Hindlimb Ischemia-Reperfusion Injury Model. ( Iuchi, K; Kamimura, N; Nishimaki, K; Ogawa, R; Ohta, S; Watanabe, M; Yokota, T, 2017) |
"Hydrogen is a kind of noble gas with the character to selectively neutralize reactive oxygen species." | 5.43 | Inhalation of water electrolysis-derived hydrogen ameliorates cerebral ischemia-reperfusion injury in rats - A possible new hydrogen resource for clinical use. ( Cao, L; Chen, X; Cui, J; Gu, Z; Hou, J; Ji, F; Li, X; Shi, D; Su, J; Sun, X; Wang, L; Weng, W; Zhai, X; Zhang, J; Zhang, R; Zhi, X, 2016) |
"Hydrogen-rich saline treatment significantly improved the amount of surviving cells (P < 0." | 5.40 | Hydrogen-rich saline attenuates neuronal ischemia--reperfusion injury by protecting mitochondrial function in rats. ( Chen, H; Cui, Y; Duan, M; Ji, M; Jia, M; Yang, J; Zhang, H, 2014) |
"Spinal cord ischemia was induced by infrarenal aortic occlusion for 20min in male New Zealand white rabbits." | 5.39 | Beneficial effects of hydrogen-rich saline against spinal cord ischemia-reperfusion injury in rabbits. ( Chen, H; Gong, G; Huang, Y; Wang, X; Xie, K; Xue, W; Zeng, Y; Zhou, L, 2013) |
"Hydrogen gas has been reported to alleviate cerebral I/R injury by acting as a free radical scavenger." | 5.39 | Protective effect of hydrogen-rich saline on ischemia/reperfusion injury in rat skin flap. ( Ma, XM; Qin, SR; Sun, XJ; Wang, ML; Wang, YB; Zhao, L; Zhong, RG, 2013) |
"Global cerebral ischemia and reperfusion (I/R) often result in high mortality." | 5.38 | Effect of hydrogen gas on the survival rate of mice following global cerebral ischemia. ( Fujita, M; Kobayashi, H; Nagatani, K; Nawashiro, H; Otani, N; Tachibana, S; Takeuchi, S; Uozumi, Y; Wada, K, 2012) |
"Spinal cord ischemia was induced by infrarenal aortic occlusion for 20 min in male New Zealand white rabbits." | 5.37 | Beneficial effects of hydrogen gas against spinal cord ischemia-reperfusion injury in rabbits. ( Dong, H; Gong, G; Huang, Y; Li, J; Wang, G; Xie, K; Xiong, L; Xu, N; Yu, Y, 2011) |
"Hydrogen gas has potent antioxidant and antiapoptotic properties and has been recently used in number of experimental and clinical studies." | 5.36 | Inhaled hydrogen gas therapy for prevention of lung transplant-induced ischemia/reperfusion injury in rats. ( Billiar, TR; Huang, CS; Kawamura, T; Lee, S; Nakao, A; Okumura, M; Shigemura, N; Tochigi, N; Toyoda, Y, 2010) |
"Hydrogen gas was reported to reduce reactive oxygen species and alleviate cerebral, myocardial and hepatic ischemia/reperfusion (I/R) injuries." | 5.35 | Hydrogen-rich saline protects against intestinal ischemia/reperfusion injury in rats. ( Cai, J; Li, Y; Liu, W; Mao, Y; Sun, P; Sun, X; Yuan, H; Zhang, JH; Zheng, X, 2009) |
" A recent study provided evidence that hydrogen inhalation exerted antioxidant and anti-apoptotic effects and protected the brain against ischemia-reperfusion injury by selectively reducing hydroxyl radical and peroxynitrite." | 4.86 | Hydrogen as a novel and effective treatment of acute carbon monoxide poisoning. ( Cai, J; He, J; Huo, Z; Shen, M; Sun, Q; Sun, X, 2010) |
"Age, APACHE score at ICU admission, neurological disease, sepsis and duration of mechanical ventilation were all independent risk factors for the development of delirium in ICU patients." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
"Lung inflation using hydrogen during CIP may improve donor lung quality by mitigating mitochondrial structural anomalies, enhancing mitochondrial function, and alleviating oxidative stress, inflammation, and apoptosis, which may be achieved through activation of the Nrf2/HO-1 pathway." | 4.31 | Inflation using hydrogen improves donor lung quality by regulating mitochondrial function during cold ischemia phase. ( Duan, L; Li, Z; Quan, L; Zhang, G; Zhang, M; Zheng, B; Zhou, H, 2023) |
"The increase in extracellular glutamate induced by spinal ischemia was significantly suppressed by 3% hydrogen gas inhalation (P < ." | 4.12 | Protective effects of hydrogen gas against spinal cord ischemia-reperfusion injury. ( Fujimoto, Y; Funao, T; Kimura, A; Mori, T; Mukai, A; Suehiro, K; Yamada, T, 2022) |
"Taken together, these results revealed the protective effect of hydrogen gas on hind limb ischemia reperfusion injury on mice by attenuating oxidative stress, impairing ER stress and apoptosis, and its ability to modulate JNK signaling pathway." | 4.02 | Protective Effect of Hydrogen Gas on Mouse Hind Limb Ischemia-Reperfusion Injury. ( Liu, J; Mei, X; Meng, J; Tong, J; Yu, P; Zhang, Y, 2021) |
"Hydrogen treatment could potentially be a future therapeutic strategy for ischemia and its derived neurodegenerative diseases by improving cognitive abilities and inducing antioxidative and antiapoptotic effects." | 4.02 | Hydrogen-Rich Water Improves Cognitive Ability and Induces Antioxidative, Antiapoptotic, and Anti-Inflammatory Effects in an Acute Ischemia-Reperfusion Injury Mouse Model. ( Choi, JI; Lee, D, 2021) |
"To investigate the effects of hydrogen-rich saline (HRS) on intestinal epithelial tight junction (TJ) barrier in rats with intestinal ischemia-reperfusion injury (IIRI)." | 3.96 | Hydrogen-rich saline protects intestinal epithelial tight junction barrier in rats with intestinal ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress-induced apoptosis pathway. ( Cheng, F; Ding, G; Fan, Q; Fu, T; Geng, L; Jiang, S; Li, Z; Xu, M, 2020) |
"Molecular hydrogen can reduce the oxidative stress of ischemia-reperfusion injury in various organs for transplantation and potentially improve survival rates in recipients." | 3.96 | Protective effects of a hydrogen-rich solution during cold ischemia in rat lung transplantation. ( Chen-Yoshikawa, TF; Date, H; Hirano, SI; Kayawake, H; Kurokawa, R; Saito, M; Takahashi, M; Yokoyama, Y, 2020) |
"Forty-five adult male Sprague Dawley rats (body weight 220-250 g) were randomly divided into three groups: (1) Sham operation group (SH), (2) Ischemia-reperfusion injury group (IR), and (3) Ischemia-reperfusion injury with preconditioning hydrogen group (PRH)." | 3.91 | Preconditioning with one-time hydrogen gas does not attenuate skin flap ischemia-reperfusion injury in rat models. ( Dong, X; Hao, Y; Liu, H; Wang, Y, 2019) |
" Hydrogen gas provides potent anti-inflammatory and antioxidant effects against ischemia-reperfusion injury (IRI)." | 3.91 | Protective effects of hydrogen inhalation during the warm ischemia phase against lung ischemia-reperfusion injury in rat donors after cardiac death. ( Deng, L; Li, W; Liu, J; Meng, C; Zhang, J; Zhou, H, 2019) |
" The hypothesis of this study is that hydrogen-rich solution could attenuateacute lung injury and improve mortality via chemerin and NLRP3 after LI/R in rats." | 3.91 | Hydrogen-Rich Saline Attenuates Acute Lung Injury Induced by Limb Ischemia/Reperfusion via Down-Regulating Chemerin and NLRP3 in Rats. ( Chen, Y; Du, J; Fan, X; Liu, KX; Wang, MH; Wang, XB; Yang, B; Zhou, J; Zou, R, 2019) |
"The present study aimed to investigate the effects of hydrogen rich saline solution (HRSS) in a rat model of ovarian ischemia-reperfusion injury." | 3.85 | Protective effect of hydrogen rich saline solution on experimental ovarian ischemia reperfusion model in rats. ( Basaklar, AC; Gokalp, N; Gulbahar, O; Karabulut, R; Poyraz, A; Sonmez, K; Turkyilmaz, Z, 2017) |
"Anti-oxidant effects of hydrogen have been reported in studies examining ischaemia-reperfusion injury (IRI)." | 3.85 | Immersing lungs in hydrogen-rich saline attenuates lung ischaemia-reperfusion injury. ( Aoyama, A; Chen-Yoshikawa, TF; Date, H; Hijiya, K; Kondo, T; Miyamoto, E; Motoyama, H; Ohata, K; Saito, M; Takahashi, M; Tanaka, S, 2017) |
"Hydrogen significantly alleviated brain tissue histological damage, promoted HO-1 expression, upregulated levels of SOD, and decreased the levels of MDA in brain tissue after the ischemia reperfusion injury." | 3.83 | The protective effects of hydrogen on HO-1 expression in the brainafter focal cerebral ischemia reperfusion in rats. ( Liu, T; Wang, X; Zhang, L; Zhao, W, 2016) |
"Lung ischemia-reperfusion injury (IRI) may be attenuated through carbon monoxide (CO)'s anti-inflammatory effect or hydrogen (H2)'s anti-oxidant effect." | 3.83 | Protection of donor lung inflation in the setting of cold ischemia against ischemia-reperfusion injury with carbon monoxide, hydrogen, or both in rats. ( Cui, X; Jiang, C; Kang, J; Liu, J; Liu, R; Ma, L; Meng, C; Niu, L; Xing, J; Zhou, H, 2016) |
"Luminal injection of hydrogen-rich solution can reduce oxidative stress and consequently ameliorate ischemic-reperfusion injury." | 3.81 | Luminal injection of hydrogen-rich solution attenuates intestinal ischemia-reperfusion injury in rats. ( Cai, S; Kasahara, M; Kurokawa, R; Li, XK; Liu, C; Nakazawa, A; Sakamoto, S; Shigeta, T; Uemoto, S, 2015) |
"The results indicate that hydrogen-rich saline could ameliorate ischemia/reperfusion injury and improve flap survival rate by inhibiting the apoptosis factor and, at the same time, promoting the expression of anti-apoptosis factor." | 3.81 | Hydrogen-rich saline attenuates skin ischemia/reperfusion induced apoptosis via regulating Bax/Bcl-2 ratio and ASK-1/JNK pathway. ( Cheng, AX; Li, JL; Liu, YF; Liu, YQ; Ma, XM; Wang, TT; Wang, YB; Xiao, YD; Xie, F; Zhang, MZ; Zhang, X; Zhao, PX, 2015) |
"Hydrogen has antioxidant and anti-inflammatory effects on lung ischemia-reperfusion injury when it is inhaled by donor or/and recipient." | 3.81 | Lung inflation with hydrogen during the cold ischemia phase decreases lung graft injury in rats. ( Fang, X; Li, W; Liu, J; Liu, R; Meng, C; Xing, J; Yang, W; Zhou, H, 2015) |
"To investigate the role of FOXO3a in process of hydrogen-rich saline attenuating global cerebral ischemia-reperfusion (I/R) injury in rats." | 3.81 | [Role of FOXO3a in process of hydrogen-rich saline attenuating global cerebral ischemia-reperfusion injury in rats]. ( Chen, X; Dai, Q; Duan, M; Gao, Y; Wu, L; Xu, J; Yu, P; Zhang, L; Zhao, L, 2015) |
"Inhalation of hydrogen could attenuate renal ischemic/reperfusion injury in rats by decreasing the content of MDA." | 3.80 | [Protective effects of hydrogen on renal ischemia/reperfusion injury in rats]. ( Chen, XJ; Huang, H; Huang, W; Jiang, XQ; Zeng, K, 2014) |
"These results suggest that, in our model, hydrogen enriched saline treatment is protective against liver ischemia-reperfusion injury." | 3.80 | Protective effects of hydrogen enriched saline on liver ischemia reperfusion injury by reducing oxidative stress and HMGB1 release. ( Irwin, MG; Liu, Y; Lloyd, DM; Ma, D; Sun, X; Tao, K; Vizcaychipi, MP; Yang, L; Yu, W, 2014) |
"Molecular hydrogen has been proven effective in ameliorating cerebral ischemia/reperfusion (I/R) injury by selectively neutralizing reactive oxygen species." | 3.79 | Lactulose ameliorates cerebral ischemia-reperfusion injury in rats by inducing hydrogen by activating Nrf2 expression. ( Bi, H; Chen, X; Kang, Z; Li, M; Liu, W; Shi, D; Shi, J; Sun, X; Wang, Q; Ye, Z; Zhai, X, 2013) |
"This study evaluated whether 2% hydrogen (H(2)) gas therapy protects against testicular ischemia/reperfusion injury which results in increased formation of reactive oxygen species and/or reactive nitrogen species, leading to testicular apoptosis and impaired spermatogenesis." | 3.78 | Inhaled hydrogen gas therapy for prevention of testicular ischemia/reperfusion injury in rats. ( Cho, YJ; Han, JS; Kim, JI; Lee, DH; Lee, JW; Lee, YA; Song, CS, 2012) |
"Results provide a biochemical and histopathological basis for the action of hydrogen rich saline solution as a therapeutic agent for testicular damage induced by ischemia/reperfusion injury." | 3.78 | Protective effects of hydrogen rich saline solution on experimental testicular ischemia-reperfusion injury in rats. ( Jiang, D; Li, Z; Sun, X; Wu, D; Xu, B; Zhang, Y, 2012) |
"Inhalation of hydrogen gas has been proved to be an effective treatment for ischemia-reperfusion injury." | 3.76 | Oral administration of mannitol may be an effective treatment for ischemia-reperfusion injury. ( Liu, S; Sun, Q; Sun, X; Tao, H, 2010) |
"Ischemia reperfusion injury (IRI) in organ transplantation has always been an important hotspot in organ protection." | 2.72 | Hydrogen: Potential Applications in Solid Organ Transplantation. ( Huang, X; Lan, Y; Lei, Y; Li, J; Liu, R; Lu, S; Luo, X; Yang, F; Zeng, F, 2021) |
"Pancreatitis is an inflammatory disease of the pancreas characterized by acinar cell injury and is associated with the abnormal release of trypsin, which results in high mortality due to systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS)." | 2.72 | Recent advances in studies of molecular hydrogen in the treatment of pancreatitis. ( Li, G; Li, Y; Suo, L; Zhang, J, 2021) |
"Hydrogen gas has been reported to have medical efficacy since the 1880s." | 2.61 | Medical Application of Hydrogen in Hematological Diseases. ( Cen, J; Pasca, S; Qian, L; Tomuleasa, C; Wu, Z, 2019) |
"1." | 2.47 | Hydrogen resuscitation, a new cytoprotective approach. ( Sun, XJ; Xia, ZF; Zheng, XF, 2011) |
"Intestinal volvulus can cause morbidity and mortality." | 1.72 | Protective Effects of Hydrogen-Rich Saline on Experimental Intestinal Volvulus in Rats. ( Dayanır, D; Karabulut, R; Karakaya, C; Kaya, C; Oral, H; Sonmez, K; Türkyılmaz, Z, 2022) |
"Hydrogen could inhibit the upregulation of autophagy in the present rodent model." | 1.62 | Hydrogen alleviates acute lung injury induced by limb ischaemia/reperfusion in mice. ( Liu, B; Liu, L; Qi, X; Qiu, T; Shen, X; Song, G; Yang, C, 2021) |
"When hydrogen gas was infused into a bag containing cold ETK organ preservation solution at a pressure of 0." | 1.51 | Organ preservation solution containing dissolved hydrogen gas from a hydrogen-absorbing alloy canister improves function of transplanted ischemic kidneys in miniature pigs. ( Kobayashi, E; Sano, M, 2019) |
"Rat livers were harvested after 30-min cardiac arrest and stored for 4 h in University of Wisconsin solution." | 1.48 | Post-reperfusion hydrogen gas treatment ameliorates ischemia reperfusion injury in rat livers from donors after cardiac death: a preliminary study. ( Fujiyoshi, M; Fujiyoshi, S; Fukai, M; Hayasaka, T; Ishikawa, T; Kawamura, N; Kimura, T; Kobayashi, N; Shibata, K; Shimada, S; Shimamura, T; Taketomi, A; Umemoto, K, 2018) |
"In renal transplantation, ischemia reperfusion injury impairs early graft function and can reduce long term graft survival." | 1.48 | Hydrogen Gas Does Not Ameliorate Renal Ischemia Reperfusion Injury in a Preclinical Model. ( Adams, T; Hosgood, SA; Moore, T; Nicholson, ML; Qurashi, M, 2018) |
"Hepatic ischemia reperfusion injury (HIRI) occurs commonly in liver surgery and liver transplantation." | 1.48 | Effect of hydrogen-rich saline on apoptosis induced by hepatic ischemia reperfusion upon laparoscopic hepatectomy in miniature pigs. ( Bai, G; Ge, Y; Jiao, Z; Kong, X; Li, H; Meng, W; Wang, H; Zhang, Q, 2018) |
"Ischemia-reperfusion injury is one of the leading causes of tissue damage and dysfunction, in particular, free tissue transfer, traumatically amputated extremity, and prolonged tourniquet application during extremity surgery." | 1.46 | Protective Effect of Hydrogen Gas Inhalation on Muscular Damage Using a Mouse Hindlimb Ischemia-Reperfusion Injury Model. ( Iuchi, K; Kamimura, N; Nishimaki, K; Ogawa, R; Ohta, S; Watanabe, M; Yokota, T, 2017) |
"Hydrogen is a kind of noble gas with the character to selectively neutralize reactive oxygen species." | 1.43 | Inhalation of water electrolysis-derived hydrogen ameliorates cerebral ischemia-reperfusion injury in rats - A possible new hydrogen resource for clinical use. ( Cao, L; Chen, X; Cui, J; Gu, Z; Hou, J; Ji, F; Li, X; Shi, D; Su, J; Sun, X; Wang, L; Weng, W; Zhai, X; Zhang, J; Zhang, R; Zhi, X, 2016) |
"Hydrogen-rich saline treatment significantly improved the amount of surviving cells (P < 0." | 1.40 | Hydrogen-rich saline attenuates neuronal ischemia--reperfusion injury by protecting mitochondrial function in rats. ( Chen, H; Cui, Y; Duan, M; Ji, M; Jia, M; Yang, J; Zhang, H, 2014) |
"Hydrogen gas has been reported to alleviate cerebral I/R injury by acting as a free radical scavenger." | 1.39 | Protective effect of hydrogen-rich saline on ischemia/reperfusion injury in rat skin flap. ( Ma, XM; Qin, SR; Sun, XJ; Wang, ML; Wang, YB; Zhao, L; Zhong, RG, 2013) |
"Spinal cord ischemia was induced by infrarenal aortic occlusion for 20min in male New Zealand white rabbits." | 1.39 | Beneficial effects of hydrogen-rich saline against spinal cord ischemia-reperfusion injury in rabbits. ( Chen, H; Gong, G; Huang, Y; Wang, X; Xie, K; Xue, W; Zeng, Y; Zhou, L, 2013) |
"The process of brain death induces acute lung injury in donors and aggravates ischemia-reperfusion injury (IRI) in grafts." | 1.39 | Hydrogen inhalation decreases lung graft injury in brain-dead donor rats. ( Cui, X; Ding, W; Fu, Z; Li, W; Liu, J; Pan, P; Wei, Y; Yang, W; Zhou, H, 2013) |
"Global cerebral ischemia and reperfusion (I/R) often result in high mortality." | 1.38 | Effect of hydrogen gas on the survival rate of mice following global cerebral ischemia. ( Fujita, M; Kobayashi, H; Nagatani, K; Nawashiro, H; Otani, N; Tachibana, S; Takeuchi, S; Uozumi, Y; Wada, K, 2012) |
"Hydrogen treatment induced several lung surfactant-related genes, ATP synthase genes and stress-response genes." | 1.38 | Profiling molecular changes induced by hydrogen treatment of lung allografts prior to procurement. ( Bermudez, CA; Billiar, TR; Isse, K; Kawamura, T; Lyons-Weiler, J; Nakao, A; Noda, K; Shigemura, N; Stolz, DB; Tanaka, Y; Toyoda, Y, 2012) |
"Hydrogen has been considered as a novel antioxidant that prevents injuries resulted from ischemia-reperfusion (I/R) injury in various tissues." | 1.37 | The effects of hydrogen-rich saline on the contractile and structural changes of intestine induced by ischemia-reperfusion in rats. ( Chen, H; Hu, PF; Li, Y; Liu, WW; Ruan, CP; Su, N; Sun, XJ; Sun, YP; Wang, Q; Xiang, HG; Yan, RL, 2011) |
"Spinal cord ischemia was induced by infrarenal aortic occlusion for 20 min in male New Zealand white rabbits." | 1.37 | Beneficial effects of hydrogen gas against spinal cord ischemia-reperfusion injury in rabbits. ( Dong, H; Gong, G; Huang, Y; Li, J; Wang, G; Xie, K; Xiong, L; Xu, N; Yu, Y, 2011) |
"Malondialdehyde (MDA) was measured to quantify the oxidative stress." | 1.37 | The effect of hydrogen-rich saline on the brain of rats with transient ischemia. ( Duan, M; Hui, K; Ji, Q; Li, W; Sun, X; Zhang, L, 2011) |
"Hydrogen gas has potent antioxidant and antiapoptotic properties and has been recently used in number of experimental and clinical studies." | 1.36 | Inhaled hydrogen gas therapy for prevention of lung transplant-induced ischemia/reperfusion injury in rats. ( Billiar, TR; Huang, CS; Kawamura, T; Lee, S; Nakao, A; Okumura, M; Shigemura, N; Tochigi, N; Toyoda, Y, 2010) |
"Hydrogen-rich saline treatment decreased the neutrophil infiltration, the lipid membrane peroxidation, NF-kappaB activation and the pro-inflammatory cytokine interleukin IL-1beta and TNF-alpha in the lung tissues compared with those in saline-treated rat." | 1.35 | Hydrogen-rich saline reduces lung injury induced by intestinal ischemia/reperfusion in rats. ( Cai, JM; Deng, XM; Jiang, L; Mao, YF; Sun, XJ; You, XM; Zhang, JH; Zheng, XF, 2009) |
"Hydrogen gas was reported to reduce reactive oxygen species and alleviate cerebral, myocardial and hepatic ischemia/reperfusion (I/R) injuries." | 1.35 | Hydrogen-rich saline protects against intestinal ischemia/reperfusion injury in rats. ( Cai, J; Li, Y; Liu, W; Mao, Y; Sun, P; Sun, X; Yuan, H; Zhang, JH; Zheng, X, 2009) |
"Hydrogen treatment resulted in significantly improved gastrointestinal transit, as well as jejunal smooth muscle contractility in response to bethanechol." | 1.35 | Hydrogen inhalation ameliorates oxidative stress in transplantation induced intestinal graft injury. ( Bauer, AJ; Billiar, TR; Buchholz, BM; Kaczorowski, DJ; McCurry, KR; Nakao, A; Sugimoto, R; Wang, Y; Yang, R, 2008) |
" The aim of this study was the validation of thermodiffusion in a new modification allowing long-term use in the clinical setting." | 1.30 | Thermodiffusion for continuous quantification of hepatic microcirculation--validation and potential in liver transplantation. ( Bleyl, J; Bowman, HF; Bredt, M; Herfarth, C; Hofmann, WJ; Klar, E; Kraus, T; Kummer, R; Newman, WH, 1999) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (3.13) | 18.2507 |
2000's | 8 (8.33) | 29.6817 |
2010's | 69 (71.88) | 24.3611 |
2020's | 16 (16.67) | 2.80 |
Authors | Studies |
---|---|
Lee, D | 1 |
Choi, JI | 1 |
Yang, F | 3 |
Lei, Y | 1 |
Liu, R | 3 |
Luo, X | 2 |
Li, J | 9 |
Zeng, F | 1 |
Lu, S | 1 |
Huang, X | 3 |
Lan, Y | 1 |
Oral, H | 1 |
Türkyılmaz, Z | 2 |
Karabulut, R | 2 |
Kaya, C | 1 |
Dayanır, D | 1 |
Karakaya, C | 1 |
Sonmez, K | 2 |
Otani, N | 2 |
Tomita, K | 1 |
Kobayashi, Y | 1 |
Kuroda, K | 1 |
Koyama, Y | 1 |
Kobayashi, H | 2 |
Kubo, T | 1 |
Fukai, M | 3 |
Sakamoto, S | 4 |
Bochimoto, H | 2 |
Zin, NKM | 1 |
Shibata, K | 3 |
Ishikawa, T | 3 |
Shimada, S | 3 |
Kawamura, N | 3 |
Fujiyoshi, M | 3 |
Fujiyoshi, S | 3 |
Nakamura, K | 2 |
Shimamura, T | 3 |
Taketomi, A | 3 |
Duan, L | 1 |
Quan, L | 1 |
Zheng, B | 1 |
Li, Z | 6 |
Zhang, G | 2 |
Zhang, M | 2 |
Zhou, H | 6 |
Zhang, Q | 7 |
Piao, C | 1 |
Xu, J | 4 |
Jiao, Z | 2 |
Ge, Y | 3 |
Liu, X | 4 |
Ma, Y | 2 |
Wang, H | 6 |
Kobayashi, E | 1 |
Sano, M | 2 |
Saito, M | 2 |
Chen-Yoshikawa, TF | 2 |
Takahashi, M | 2 |
Kayawake, H | 1 |
Yokoyama, Y | 1 |
Kurokawa, R | 2 |
Hirano, SI | 1 |
Date, H | 2 |
Qian, L | 1 |
Wu, Z | 1 |
Cen, J | 1 |
Pasca, S | 1 |
Tomuleasa, C | 1 |
Jiang, S | 1 |
Fan, Q | 1 |
Xu, M | 1 |
Cheng, F | 1 |
Ding, G | 1 |
Geng, L | 1 |
Fu, T | 1 |
Halim, AA | 1 |
Alsayed, B | 1 |
Embarak, S | 1 |
Yaseen, T | 1 |
Dabbous, S | 1 |
Fontaine, O | 1 |
Dueluzeau, R | 1 |
Raibaud, P | 1 |
Chabanet, C | 1 |
Popoff, MR | 1 |
Badoual, J | 1 |
Gabilan, JC | 1 |
Andremont, A | 1 |
Gómez, L | 1 |
Andrés, S | 1 |
Sánchez, J | 1 |
Alonso, JM | 1 |
Rey, J | 1 |
López, F | 1 |
Jiménez, A | 1 |
Yan, Z | 1 |
Zhou, L | 2 |
Zhao, Y | 3 |
Wang, J | 6 |
Huang, L | 2 |
Hu, K | 1 |
Liu, H | 6 |
Guo, Z | 1 |
Song, Y | 1 |
Huang, H | 5 |
Yang, R | 2 |
Owen, TW | 1 |
Al-Kaysi, RO | 1 |
Bardeen, CJ | 1 |
Cheng, Q | 1 |
Wu, S | 1 |
Cheng, T | 1 |
Zhou, X | 1 |
Wang, B | 4 |
Wu, X | 3 |
Yao, Y | 3 |
Ochiai, T | 1 |
Ishiguro, H | 2 |
Nakano, R | 2 |
Kubota, Y | 2 |
Hara, M | 1 |
Sunada, K | 1 |
Hashimoto, K | 1 |
Kajioka, J | 1 |
Fujishima, A | 1 |
Jiao, J | 3 |
Gai, QY | 3 |
Wang, W | 3 |
Zang, YP | 2 |
Niu, LL | 2 |
Fu, YJ | 3 |
Wang, X | 6 |
Yao, LP | 1 |
Qin, QP | 1 |
Wang, ZY | 1 |
Liu, J | 10 |
Aleksic Sabo, V | 1 |
Knezevic, P | 1 |
Borges-Argáez, R | 1 |
Chan-Balan, R | 1 |
Cetina-Montejo, L | 1 |
Ayora-Talavera, G | 1 |
Sansores-Peraza, P | 1 |
Gómez-Carballo, J | 1 |
Cáceres-Farfán, M | 1 |
Jang, J | 1 |
Akin, D | 1 |
Bashir, R | 1 |
Yu, Z | 1 |
Zhu, J | 2 |
Jiang, H | 1 |
He, C | 2 |
Xiao, Z | 1 |
Sun, Q | 6 |
Han, D | 1 |
Lei, H | 1 |
Zhao, K | 2 |
Zhu, L | 1 |
Li, X | 6 |
Fu, H | 2 |
Wilson, BK | 1 |
Step, DL | 1 |
Maxwell, CL | 1 |
Gifford, CA | 1 |
Richards, CJ | 1 |
Krehbiel, CR | 1 |
Warner, JM | 1 |
Doerr, AJ | 1 |
Erickson, GE | 1 |
Guretzky, JA | 1 |
Rasby, RJ | 1 |
Watson, AK | 1 |
Klopfenstein, TJ | 1 |
Sun, Y | 4 |
Liu, Z | 3 |
Pham, TD | 1 |
Lee, BK | 1 |
Yang, FC | 1 |
Wu, KH | 1 |
Lin, WP | 1 |
Hu, MK | 1 |
Lin, L | 3 |
Shao, J | 1 |
Sun, M | 1 |
Xu, G | 1 |
Zhang, X | 8 |
Xu, N | 2 |
Wang, R | 3 |
Liu, S | 2 |
He, H | 1 |
Dong, X | 3 |
Yang, M | 2 |
Yang, Q | 1 |
Duan, S | 1 |
Yu, Y | 4 |
Han, J | 2 |
Zhang, C | 3 |
Chen, L | 3 |
Yang, X | 1 |
Li, W | 7 |
Wang, T | 2 |
Campbell, DA | 1 |
Gao, K | 1 |
Zager, RA | 1 |
Johnson, ACM | 1 |
Guillem, A | 1 |
Keyser, J | 1 |
Singh, B | 1 |
Steubl, D | 1 |
Schneider, MP | 1 |
Meiselbach, H | 1 |
Nadal, J | 1 |
Schmid, MC | 1 |
Saritas, T | 1 |
Krane, V | 1 |
Sommerer, C | 1 |
Baid-Agrawal, S | 1 |
Voelkl, J | 1 |
Kotsis, F | 1 |
Köttgen, A | 1 |
Eckardt, KU | 1 |
Scherberich, JE | 1 |
Li, H | 7 |
Yao, L | 2 |
Sun, L | 3 |
Zhu, Z | 1 |
Naren, N | 1 |
Zhang, XX | 2 |
Gentile, GL | 1 |
Rupert, AS | 1 |
Carrasco, LI | 1 |
Garcia, EM | 1 |
Kumar, NG | 1 |
Walsh, SW | 1 |
Jefferson, KK | 1 |
Guest, RL | 1 |
Samé Guerra, D | 1 |
Wissler, M | 1 |
Grimm, J | 1 |
Silhavy, TJ | 1 |
Lee, JH | 2 |
Yoo, JS | 1 |
Kim, Y | 1 |
Kim, JS | 2 |
Lee, EJ | 1 |
Roe, JH | 1 |
Delorme, M | 1 |
Bouchard, PA | 1 |
Simon, M | 1 |
Simard, S | 1 |
Lellouche, F | 1 |
D'Urzo, KA | 1 |
Mok, F | 1 |
D'Urzo, AD | 1 |
Koneru, B | 1 |
Lopez, G | 1 |
Farooqi, A | 1 |
Conkrite, KL | 1 |
Nguyen, TH | 1 |
Macha, SJ | 1 |
Modi, A | 1 |
Rokita, JL | 1 |
Urias, E | 1 |
Hindle, A | 1 |
Davidson, H | 1 |
Mccoy, K | 1 |
Nance, J | 1 |
Yazdani, V | 1 |
Irwin, MS | 1 |
Yang, S | 1 |
Wheeler, DA | 1 |
Maris, JM | 1 |
Diskin, SJ | 1 |
Reynolds, CP | 1 |
Abhilash, L | 1 |
Kalliyil, A | 1 |
Sheeba, V | 1 |
Hartley, AM | 2 |
Meunier, B | 2 |
Pinotsis, N | 1 |
Maréchal, A | 2 |
Xu, JY | 1 |
Genko, N | 1 |
Haraux, F | 1 |
Rich, PR | 1 |
Kamalanathan, M | 1 |
Doyle, SM | 1 |
Xu, C | 1 |
Achberger, AM | 1 |
Wade, TL | 1 |
Schwehr, K | 1 |
Santschi, PH | 1 |
Sylvan, JB | 1 |
Quigg, A | 1 |
Leong, W | 1 |
Xu, W | 2 |
Gao, S | 1 |
Zhai, X | 3 |
Wang, C | 2 |
Gilson, E | 1 |
Ye, J | 1 |
Lu, Y | 1 |
Yan, R | 1 |
Zhang, Y | 8 |
Hu, Z | 1 |
You, Q | 1 |
Cai, Q | 1 |
Yang, D | 2 |
Gu, S | 1 |
Dai, H | 1 |
Zhao, X | 1 |
Gui, C | 1 |
Gui, J | 1 |
Wu, PK | 1 |
Hong, SK | 1 |
Starenki, D | 1 |
Oshima, K | 1 |
Shao, H | 1 |
Gestwicki, JE | 1 |
Tsai, S | 1 |
Park, JI | 1 |
Wang, Y | 9 |
Zhao, R | 1 |
Gu, Z | 2 |
Dong, C | 2 |
Guo, G | 1 |
Li, L | 4 |
Barrett, HE | 1 |
Meester, EJ | 1 |
van Gaalen, K | 1 |
van der Heiden, K | 1 |
Krenning, BJ | 1 |
Beekman, FJ | 1 |
de Blois, E | 1 |
de Swart, J | 1 |
Verhagen, HJ | 1 |
Maina, T | 1 |
Nock, BA | 1 |
Norenberg, JP | 1 |
de Jong, M | 1 |
Gijsen, FJH | 1 |
Bernsen, MR | 1 |
Martínez-Milla, J | 1 |
Galán-Arriola, C | 1 |
Carnero, M | 1 |
Cobiella, J | 1 |
Pérez-Camargo, D | 1 |
Bautista-Hernández, V | 1 |
Rigol, M | 1 |
Solanes, N | 1 |
Villena-Gutierrez, R | 1 |
Lobo, M | 1 |
Mateo, J | 1 |
Vilchez-Tschischke, JP | 1 |
Salinas, B | 1 |
Cussó, L | 1 |
López, GJ | 1 |
Fuster, V | 1 |
Desco, M | 1 |
Sanchez-González, J | 1 |
Ibanez, B | 1 |
van den Berg, P | 1 |
Schweitzer, DH | 1 |
van Haard, PMM | 1 |
Geusens, PP | 1 |
van den Bergh, JP | 1 |
Zhu, X | 1 |
Xu, H | 2 |
Yang, G | 2 |
Lin, Z | 1 |
Salem, HF | 1 |
Nafady, MM | 1 |
Kharshoum, RM | 1 |
Abd El-Ghafar, OA | 1 |
Farouk, HO | 1 |
Domiciano, D | 1 |
Nery, FC | 1 |
de Carvalho, PA | 1 |
Prudente, DO | 1 |
de Souza, LB | 1 |
Chalfun-Júnior, A | 1 |
Paiva, R | 1 |
Marchiori, PER | 1 |
Lu, M | 2 |
An, Z | 1 |
Jiang, J | 2 |
Du, S | 1 |
Cui, J | 3 |
Wu, W | 1 |
Liu, Y | 9 |
Song, J | 1 |
Lian, Q | 1 |
Uddin Ahmad, Z | 1 |
Gang, DD | 1 |
Konggidinata, MI | 1 |
Gallo, AA | 1 |
Zappi, ME | 1 |
Yang, TWW | 1 |
Johari, Y | 1 |
Burton, PR | 1 |
Earnest, A | 1 |
Shaw, K | 1 |
Hare, JL | 1 |
Brown, WA | 1 |
Kim, GA | 1 |
Han, S | 1 |
Choi, GH | 1 |
Choi, J | 1 |
Lim, YS | 1 |
Gallo, A | 1 |
Cancelli, C | 1 |
Ceron, E | 1 |
Covino, M | 1 |
Capoluongo, E | 1 |
Pocino, K | 1 |
Ianiro, G | 1 |
Cammarota, G | 1 |
Gasbarrini, A | 1 |
Montalto, M | 1 |
Somasundar, Y | 1 |
Lu, IC | 1 |
Mills, MR | 1 |
Qian, LY | 1 |
Olivares, X | 1 |
Ryabov, AD | 1 |
Collins, TJ | 1 |
Zhao, L | 3 |
Doddipatla, S | 1 |
Thomas, AM | 1 |
Nikolayev, AA | 1 |
Galimova, GR | 1 |
Azyazov, VN | 1 |
Mebel, AM | 1 |
Kaiser, RI | 1 |
Guo, S | 1 |
Yang, P | 1 |
Yu, X | 2 |
Wu, Y | 2 |
Zhang, H | 2 |
Yu, B | 2 |
Han, B | 1 |
George, MW | 1 |
Moor, MB | 1 |
Bonny, O | 1 |
Langenberg, E | 1 |
Paik, H | 1 |
Smith, EH | 1 |
Nair, HP | 1 |
Hanke, I | 1 |
Ganschow, S | 1 |
Catalan, G | 1 |
Domingo, N | 1 |
Schlom, DG | 1 |
Assefa, MK | 1 |
Wu, G | 2 |
Hayton, TW | 1 |
Becker, B | 1 |
Enikeev, D | 1 |
Netsch, C | 1 |
Gross, AJ | 1 |
Laukhtina, E | 1 |
Glybochko, P | 1 |
Rapoport, L | 1 |
Herrmann, TRW | 1 |
Taratkin, M | 1 |
Dai, W | 1 |
Shi, J | 4 |
Carreno, J | 1 |
Kloner, RA | 1 |
Pickersgill, NA | 1 |
Vetter, JM | 1 |
Kim, EH | 1 |
Cope, SJ | 1 |
Du, K | 1 |
Venkatesh, R | 1 |
Giardina, JD | 1 |
Saad, NES | 1 |
Bhayani, SB | 1 |
Figenshau, RS | 1 |
Eriksson, J | 1 |
Landfeldt, E | 1 |
Ireland, S | 1 |
Jackson, C | 1 |
Wyatt, E | 1 |
Gaudig, M | 1 |
Stancill, JS | 1 |
Happ, JT | 1 |
Broniowska, KA | 1 |
Hogg, N | 1 |
Corbett, JA | 1 |
Tang, LF | 1 |
Bi, YL | 1 |
Fan, Y | 2 |
Sun, YB | 1 |
Wang, AL | 1 |
Xiao, BH | 1 |
Wang, LF | 1 |
Qiu, SW | 1 |
Guo, SW | 1 |
Wáng, YXJ | 1 |
Sun, J | 2 |
Chu, S | 1 |
Pan, Q | 1 |
Li, D | 3 |
Zheng, S | 2 |
Ma, L | 2 |
Wang, L | 4 |
Hu, T | 1 |
Wang, F | 2 |
Han, Z | 1 |
Yin, Z | 1 |
Ge, X | 1 |
Xie, K | 4 |
Lei, P | 1 |
Dias-Santagata, D | 1 |
Lennerz, JK | 1 |
Sadow, PM | 1 |
Frazier, RP | 1 |
Govinda Raju, S | 1 |
Henry, D | 1 |
Chung, T | 1 |
Kherani, J | 1 |
Rothenberg, SM | 1 |
Wirth, LJ | 1 |
Marti, CN | 1 |
Choi, NG | 1 |
Bae, SJ | 1 |
Ni, L | 1 |
Dai, T | 1 |
Yang, Y | 5 |
Lee, R | 1 |
Fleischer, AS | 1 |
Wemhoff, AP | 1 |
Ford, CR | 1 |
Kleppinger, EL | 1 |
Helms, K | 1 |
Bush, AA | 1 |
Luna-Abanto, J | 1 |
García Ruiz, L | 1 |
Laura Martinez, J | 1 |
Álvarez Larraondo, M | 1 |
Villoslada Terrones, V | 1 |
Dukic, L | 1 |
Maric, N | 1 |
Simundic, AM | 1 |
Chogtu, B | 1 |
Ommurugan, B | 1 |
Thomson, SR | 1 |
Kalthur, SG | 1 |
Benidir, M | 1 |
El Massoudi, S | 1 |
El Ghadraoui, L | 1 |
Lazraq, A | 1 |
Benjelloun, M | 1 |
Errachidi, F | 1 |
Cassar, M | 1 |
Law, AD | 1 |
Chow, ES | 1 |
Giebultowicz, JM | 1 |
Kretzschmar, D | 1 |
Salonurmi, T | 1 |
Nabil, H | 1 |
Ronkainen, J | 1 |
Hyötyläinen, T | 1 |
Hautajärvi, H | 1 |
Savolainen, MJ | 1 |
Tolonen, A | 1 |
Orešič, M | 1 |
Känsäkoski, P | 1 |
Rysä, J | 1 |
Hakkola, J | 1 |
Hukkanen, J | 1 |
Zhu, N | 1 |
Li, Y | 7 |
Du, Q | 1 |
Hao, P | 1 |
Cao, X | 1 |
Li, CX | 1 |
Zhao, S | 1 |
Luo, XM | 1 |
Feng, JX | 1 |
Gonzalez-Cotto, M | 1 |
Guo, L | 1 |
Karwan, M | 1 |
Sen, SK | 1 |
Barb, J | 1 |
Collado, CJ | 1 |
Elloumi, F | 1 |
Palmieri, EM | 1 |
Boelte, K | 1 |
Kolodgie, FD | 1 |
Finn, AV | 1 |
Biesecker, LG | 1 |
McVicar, DW | 1 |
Qu, F | 1 |
Deng, Z | 1 |
Xie, Y | 2 |
Tang, J | 3 |
Chen, Z | 4 |
Luo, W | 1 |
Xiong, D | 1 |
Zhao, D | 1 |
Fang, J | 1 |
Zhou, Z | 1 |
Niu, PP | 1 |
Song, B | 1 |
Xu, YM | 1 |
Zhang, Z | 2 |
Qiu, N | 1 |
Yin, J | 1 |
Zhang, J | 8 |
Guo, W | 1 |
Liu, M | 2 |
Liu, T | 3 |
Chen, D | 5 |
Luo, K | 1 |
He, Z | 2 |
Zheng, G | 1 |
Xu, F | 1 |
Sun, W | 1 |
Yin, F | 1 |
van Hest, JCM | 1 |
Du, L | 2 |
Shi, X | 1 |
Kang, S | 1 |
Duan, W | 1 |
Zhang, S | 2 |
Feng, J | 2 |
Qi, N | 1 |
Shen, G | 1 |
Ren, H | 1 |
Shang, Q | 1 |
Zhao, W | 3 |
Yang, Z | 3 |
Jiang, X | 2 |
Alame, M | 1 |
Cornillot, E | 1 |
Cacheux, V | 1 |
Tosato, G | 1 |
Four, M | 1 |
De Oliveira, L | 1 |
Gofflot, S | 1 |
Delvenne, P | 1 |
Turtoi, E | 1 |
Cabello-Aguilar, S | 1 |
Nishiyama, M | 1 |
Turtoi, A | 1 |
Costes-Martineau, V | 1 |
Colinge, J | 1 |
Guo, Q | 1 |
Quan, M | 1 |
Dong, J | 1 |
Bai, J | 1 |
Han, R | 1 |
Cai, Y | 1 |
Lv, YQ | 1 |
Chen, Q | 1 |
Lyu, HD | 1 |
Deng, L | 2 |
Zhou, D | 1 |
Xiao, X | 1 |
De Langhe, S | 1 |
Billadeau, DD | 1 |
Lou, Z | 1 |
Zhang, JS | 1 |
Xue, Z | 1 |
Shen, XD | 1 |
Gao, F | 1 |
Busuttil, RW | 1 |
Kupiec-Weglinski, JW | 1 |
Ji, H | 1 |
Otano, I | 1 |
Alvarez, M | 1 |
Minute, L | 1 |
Ochoa, MC | 1 |
Migueliz, I | 1 |
Molina, C | 1 |
Azpilikueta, A | 1 |
de Andrea, CE | 1 |
Etxeberria, I | 1 |
Sanmamed, MF | 1 |
Teijeira, Á | 1 |
Berraondo, P | 1 |
Melero, I | 1 |
Zhong, Z | 1 |
Xie, X | 1 |
Yu, Q | 1 |
Zhou, C | 1 |
Liu, C | 6 |
Liu, W | 3 |
Chen, W | 1 |
Yin, Y | 1 |
Li, CW | 1 |
Hsu, JL | 1 |
Zhou, Q | 1 |
Hu, B | 1 |
Fu, P | 1 |
Atyah, M | 1 |
Ma, Q | 2 |
Xu, Y | 1 |
Dong, Q | 1 |
Hung, MC | 1 |
Ren, N | 1 |
Huang, P | 1 |
Liao, R | 1 |
Chen, X | 7 |
Cao, Q | 1 |
Yuan, X | 1 |
Nie, W | 1 |
Yang, J | 3 |
Shao, B | 1 |
Ma, X | 1 |
Bi, Z | 1 |
Liang, X | 1 |
Tie, Y | 1 |
Mo, F | 1 |
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Wei, X | 2 |
Dokla, EME | 1 |
Fang, CS | 1 |
Chu, PC | 1 |
Chang, CS | 1 |
Abouzid, KAM | 1 |
Chen, CS | 1 |
Blaszczyk, R | 1 |
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Dymek, B | 1 |
Stanczak, PS | 1 |
Mazurkiewicz, M | 1 |
Olczak, J | 1 |
Nowicka, J | 1 |
Dzwonek, K | 1 |
Zagozdzon, A | 1 |
Golab, J | 1 |
Golebiowski, A | 1 |
Xin, Z | 1 |
Himmelbauer, MK | 1 |
Jones, JH | 1 |
Enyedy, I | 1 |
Gilfillan, R | 1 |
Hesson, T | 1 |
King, K | 1 |
Marcotte, DJ | 1 |
Murugan, P | 1 |
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Gonzalez-Lopez de Turiso, F | 1 |
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Boudot, C | 1 |
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Pratviel, G | 1 |
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Mazier, D | 1 |
Corvaisier, S | 1 |
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Malzert-Fréon, A | 1 |
Wyllie, S | 1 |
Milne, R | 1 |
Fairlamb, AH | 1 |
Valentin, A | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Hydrogen-Rich Celsior Solution Improve the Quality of Aging DBD Grafts in Liver/Kidney Transplantation: Prospective, Randomized Clinical Trial[NCT02613195] | Phase 3 | 20 participants (Anticipated) | Interventional | 2016-01-31 | Not yet recruiting | ||
The Effect of Perioperative Hydrogen Inhalation on Post-operative Pain and Inflammation Cytokines[NCT05476575] | 32 participants (Anticipated) | Interventional | 2021-10-28 | Recruiting | |||
Efficacy and Safety of Hydrogen Inhalation on Bronchiectasis (HYBRID): A Randomized, Multi-center, Double-blind, Parallel-group Study[NCT02765295] | 120 participants (Anticipated) | Interventional | 2016-06-01 | Recruiting | |||
Evaluation of the Daily Intake of 0.5 L of Water Saturated With Molecular Hydrogen for 21 Days in COVID-19 Patients Treated in Ambulatory Care. Double-blind, Randomized, Comparative Study[NCT04716985] | 700 participants (Actual) | Interventional | 2021-01-22 | Active, not recruiting | |||
Adjuvant Therapy for Severe COPD Patients in the Stable Phase by an Oxyhydrogen Generator With Nebulizer: A Multi-centric, Randomized, Parallel-control and Double-blinded Clinic Study[NCT02850185] | 170 participants (Anticipated) | Interventional | 2016-07-15 | Recruiting | |||
Adjuvant Therapy for Severe Asthma by an Oxyhydrogen Generator With Nebulizer: A Multi-centric, Randomized, Parallel-control and Double-blinded Clinic Study on Effectiveness and Safety[NCT02883582] | 150 participants (Anticipated) | Interventional | 2016-08-31 | Recruiting | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
11 reviews available for hydrogen and Injury, Ischemia-Reperfusion
Article | Year |
---|---|
Hydrogen: Potential Applications in Solid Organ Transplantation.
Topics: Humans; Hydrogen; Organ Transplantation; Reperfusion Injury | 2021 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Medical Application of Hydrogen in Hematological Diseases.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Disease Models, Animal; Humans; Hydrogen | 2019 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Recent advances in studies of molecular hydrogen in the treatment of pancreatitis.
Topics: Animals; Antioxidants; Apoptosis; Autophagy; Cell Death; Endoplasmic Reticulum Stress; Humans; Hydro | 2021 |
Hydrogen Gas Therapy: From Preclinical Studies to Clinical Trials.
Topics: Anti-Inflammatory Agents; COVID-19; Humans; Hydrogen; Reperfusion Injury; SARS-CoV-2 | 2021 |
[Initiation, development and potential of hydrogen medicine: Toward therapeutic and preventive applications of molecular hydrogen against a variety of diseases].
Topics: Animals; Antioxidants; Gene Expression; Humans; Hydrogen; Neurodegenerative Diseases; Oxidative Stre | 2015 |
Hydrogen, a potential safeguard for graft-versus-host disease and graft ischemia-reperfusion injury?
Topics: Animals; Antioxidants; Cytokines; Graft vs Host Disease; Hydrogen; Organ Transplantation; Oxidative | 2016 |
Hydrogen as a novel and effective treatment of acute carbon monoxide poisoning.
Topics: Antioxidants; Brain; Carbon Monoxide Poisoning; Cell Death; Free Radical Scavengers; Free Radicals; | 2010 |
Hydrogen resuscitation, a new cytoprotective approach.
Topics: Animals; Antioxidants; Apoptosis; Cytoprotection; Humans; Hydrogen; Reperfusion Injury | 2011 |
[Hydrogen and oxidative stress injury--from an inert gas to a medical gas].
Topics: Antioxidants; Humans; Hydrogen; Oxidative Stress; Reactive Oxygen Species; Reperfusion Injury | 2011 |
2 trials available for hydrogen and Injury, Ischemia-Reperfusion
Article | Year |
---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
85 other studies available for hydrogen and Injury, Ischemia-Reperfusion
Article | Year |
---|---|
Hydrogen-Rich Water Improves Cognitive Ability and Induces Antioxidative, Antiapoptotic, and Anti-Inflammatory Effects in an Acute Ischemia-Reperfusion Injury Mouse Model.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Brain Ischemia; Cognition; Deuterium Oxi | 2021 |
Protective Effects of Hydrogen-Rich Saline on Experimental Intestinal Volvulus in Rats.
Topics: Animals; Antioxidants; Hydrogen; Intestinal Volvulus; Oxidative Stress; Rats; Reperfusion Injury; Sa | 2022 |
Hydrogen-generating Si-based agent protects against skin flap ischemia-reperfusion injury in rats.
Topics: Animals; Disease Models, Animal; Hydrogen; Inflammation; Rats; Rats, Sprague-Dawley; Reperfusion Inj | 2022 |
Hypothermic Machine Perfusion with Hydrogen Gas Reduces Focal Injury in Rat Livers but Fails to Restore Organ Function.
Topics: Animals; Hydrogen; Liver; Liver Transplantation; Organ Preservation; Perfusion; Rats; Reperfusion In | 2023 |
Combination of Cold Storage in a Heavy Water-Containing Solution and Post-Reperfusion Hydrogen Gas Treatment Reduces Ischemia-Reperfusion Injury in Rat Livers.
Topics: Animals; Deuterium Oxide; Glutathione; Hydrogen; Insulin; Liver; Organ Preservation; Organ Preservat | 2023 |
Inflation using hydrogen improves donor lung quality by regulating mitochondrial function during cold ischemia phase.
Topics: Apoptosis; Cold Ischemia; Heme Oxygenase-1; Humans; Hydrogen; Inflammation; Lung; NF-E2-Related Fact | 2023 |
Comparative study on protective effect of hydrogen rich saline and adipose-derived stem cells on hepatic ischemia-reperfusion and hepatectomy injury in swine.
Topics: Adipocytes; Animals; Apoptosis; Hepatectomy; Hydrogen; Inflammation; Liver; Liver Function Tests; Li | 2019 |
Organ preservation solution containing dissolved hydrogen gas from a hydrogen-absorbing alloy canister improves function of transplanted ischemic kidneys in miniature pigs.
Topics: Alloys; Animals; Disease Models, Animal; Gases; Graft Survival; Humans; Hydrogen; Ischemia; Kidney; | 2019 |
Protective effects of a hydrogen-rich solution during cold ischemia in rat lung transplantation.
Topics: Animals; Cold Ischemia; Cytokines; Disease Models, Animal; Hydrogen; Lung; Lung Transplantation; Mal | 2020 |
Hydrogen-rich saline protects intestinal epithelial tight junction barrier in rats with intestinal ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress-induced apoptosis pathway.
Topics: Animals; Apoptosis; Endoplasmic Reticulum Stress; Hydrogen; Male; Rats; Rats, Sprague-Dawley; Reperf | 2020 |
Hydrogen gas inhalation alleviates myocardial ischemia-reperfusion injury by the inhibition of oxidative stress and NLRP3-mediated pyroptosis in rats.
Topics: Administration, Inhalation; Animals; Cell Survival; Hydrogen; Inflammasomes; Male; Myocardial Infarc | 2021 |
Protective Effect of Hydrogen Gas on Mouse Hind Limb Ischemia-Reperfusion Injury.
Topics: Administration, Inhalation; Animals; Apoptosis; Biomarkers; Endoplasmic Reticulum Stress; Hindlimb; | 2021 |
Hydrogen alleviates acute lung injury induced by limb ischaemia/reperfusion in mice.
Topics: Acute Lung Injury; Animals; Extremities; Heme Oxygenase-1; Hydrogen; Male; Malondialdehyde; Mice; Mi | 2021 |
Protective effects of hydrogen gas against spinal cord ischemia-reperfusion injury.
Topics: Amino Acid Transport System X-AG; Animals; Disease Models, Animal; Glutamates; Hydrogen; Ischemia; M | 2022 |
Immersing lungs in hydrogen-rich saline attenuates lung ischaemia-reperfusion injury.
Topics: Animals; Antioxidants; Cytokines; Hydrogen; Inflammation Mediators; Lung; Lung Compliance; Organ Pre | 2017 |
Hydrogen saline suppresses neuronal cell apoptosis and inhibits the p38 mitogen‑activated protein kinase‑caspase‑3 signaling pathway following cerebral ischemia‑reperfusion injury.
Topics: Animals; Apoptosis; Brain Ischemia; Caspase 3; Gene Expression; Hydrogen; Immunohistochemistry; Male | 2017 |
Hydrogen-Rich Saline Ameliorates Hepatic Ischemia-Reperfusion Injury Through Regulation of Endoplasmic Reticulum Stress and Apoptosis.
Topics: Animals; Apoptosis; Endoplasmic Reticulum Stress; Hepatic Insufficiency; Hydrogen; Liver; Male; Malo | 2017 |
Hydrogen-rich saline protects against small-scale liver ischemia-reperfusion injury by inhibiting endoplasmic reticulum stress.
Topics: Animals; Apoptosis; Endoplasmic Reticulum Stress; Hydrogen; Liver; Liver Diseases; Protective Agents | 2018 |
Hydrogen postconditioning promotes survival of rat retinal ganglion cells against ischemia/reperfusion injury through the PI3K/Akt pathway.
Topics: Administration, Inhalation; Animals; Cell Survival; Hydrogen; Male; Phosphatidylinositol 3-Kinases; | 2018 |
Hydrogen Gas Does Not Ameliorate Renal Ischemia Reperfusion Injury in a Preclinical Model.
Topics: Animals; Cold Ischemia; Disease Models, Animal; Hydrogen; Kidney; Kidney Transplantation; Oxidative | 2018 |
Hydrogen-Rich Saline Attenuates Acute Lung Injury Induced by Limb Ischemia/Reperfusion via Down-Regulating Chemerin and NLRP3 in Rats.
Topics: Acute Lung Injury; Animals; Blood Gas Analysis; Chemokines; Enzyme-Linked Immunosorbent Assay; Hydro | 2019 |
Hydrogen exerts neuroprotective effects on OGD/R damaged neurons in rat hippocampal by protecting mitochondrial function via regulating mitophagy mediated by PINK1/Parkin signaling pathway.
Topics: Animals; Apoptosis; Autophagy; Brain Ischemia; Cell Survival; Hippocampus; Hydrogen; Membrane Potent | 2018 |
Post-reperfusion hydrogen gas treatment ameliorates ischemia reperfusion injury in rat livers from donors after cardiac death: a preliminary study.
Topics: Animals; Cell Death; Cold Temperature; Cytoplasm; Death; Gases; Graft Survival; Heart Arrest; Hydrog | 2018 |
Effect of hydrogen-rich saline on apoptosis induced by hepatic ischemia reperfusion upon laparoscopic hepatectomy in miniature pigs.
Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Hepatectomy; Hydrogen; Laparo | 2018 |
Hydrogen-rich saline protects rat from oxygen glucose deprivation and reperusion-induced apoptosis through VDAC1 via Bcl-2.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 9; Cell Death; Cell Hypoxia; Cell Survival; | 2019 |
Hydrogen-rich solution attenuates cold ischemia-reperfusion injury in rat liver transplantation.
Topics: Adenosine; Allopurinol; Animals; Apoptosis; Cold Temperature; Glutathione; Hepatocytes; Hydrogen; Hy | 2019 |
Protective Effect of Hydrogen Gas Inhalation on Muscular Damage Using a Mouse Hindlimb Ischemia-Reperfusion Injury Model.
Topics: Administration, Inhalation; Animals; Disease Models, Animal; Hindlimb; Humans; Hydrogen; Male; Mice; | 2017 |
Protective effects of hydrogen inhalation during the warm ischemia phase against lung ischemia-reperfusion injury in rat donors after cardiac death.
Topics: Administration, Inhalation; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Disease Mode | 2019 |
UPLC-QTOF/MS-Based Metabolomics Reveals the Protective Mechanism of Hydrogen on Mice with Ischemic Stroke.
Topics: Animals; Brain; Chromatography, High Pressure Liquid; Energy Metabolism; Glutathione; Hydrogen; Infa | 2019 |
Preconditioning with one-time hydrogen gas does not attenuate skin flap ischemia-reperfusion injury in rat models.
Topics: Analysis of Variance; Animals; Biopsy, Needle; Disease Models, Animal; Epigastric Arteries; Graft Re | 2019 |
Beneficial effects of hydrogen-rich saline against spinal cord ischemia-reperfusion injury in rabbits.
Topics: Acyl Coenzyme A; Animals; Caspase 3; Catalase; Cytokines; Dinoprost; Disease Models, Animal; Dose-Re | 2013 |
Protective effect of hydrogen-rich saline on ischemia/reperfusion injury in rat skin flap.
Topics: Animals; Hydrogen; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Skin; | 2013 |
Lactulose ameliorates cerebral ischemia-reperfusion injury in rats by inducing hydrogen by activating Nrf2 expression.
Topics: Animals; Blotting, Western; Brain; Brain Ischemia; Hydrogen; Immunohistochemistry; In Situ Nick-End | 2013 |
Protective effects of hydrogen enriched saline on liver ischemia reperfusion injury by reducing oxidative stress and HMGB1 release.
Topics: Alanine Transaminase; Animals; Down-Regulation; Guanosine; HMGB1 Protein; Hydrogen; Interleukin-6; L | 2014 |
Maternal molecular hydrogen administration ameliorates rat fetal hippocampal damage caused by in utero ischemia-reperfusion.
Topics: Animals; Female; Hippocampus; Humans; Hydrogen; Infant, Newborn; Lipid Peroxidation; Maternal-Fetal | 2014 |
[Protective effects of hydrogen on renal ischemia/reperfusion injury in rats].
Topics: Animals; Blood Urea Nitrogen; Creatinine; Hydrogen; Kidney; Male; Malondialdehyde; Nephrectomy; Rats | 2014 |
Beneficial effects of hydrogen gas on porcine liver reperfusion injury with use of total vascular exclusion and active venous bypass.
Topics: Animals; Antioxidants; Aspartate Aminotransferases; Biomarkers; Disease Models, Animal; Female; Gase | 2014 |
Hydrogen-rich saline attenuates neuronal ischemia--reperfusion injury by protecting mitochondrial function in rats.
Topics: Animals; Antioxidants; Apoptosis; Brain Ischemia; Calcium; Cell Survival; Cytochromes c; Hydrogen; I | 2014 |
Luminal injection of hydrogen-rich solution attenuates intestinal ischemia-reperfusion injury in rats.
Topics: Administration, Inhalation; Administration, Oral; Animals; Antioxidants; Apoptosis; Cytokines; Gluco | 2015 |
Hydrogen-rich saline attenuates ischemia-reperfusion injury in skeletal muscle.
Topics: Animals; Antioxidants; Apoptosis; Autophagy; Drug Evaluation, Preclinical; Edema; Hydrogen; Male; Mu | 2015 |
Lung inflation with hydrogen during the cold ischemia phase decreases lung graft injury in rats.
Topics: Animals; Antioxidants; Apoptosis; Cold Ischemia; Hydrogen; Lung Compliance; Lung Injury; Lung Transp | 2015 |
[Role of FOXO3a in process of hydrogen-rich saline attenuating global cerebral ischemia-reperfusion injury in rats].
Topics: Animals; Brain Ischemia; Forkhead Box Protein O3; Forkhead Transcription Factors; Hippocampus; Hydro | 2015 |
Hydrogen-rich saline reduces cell death through inhibition of DNA oxidative stress and overactivation of poly (ADP-ribose) polymerase-1 in retinal ischemia-reperfusion injury.
Topics: Animals; Apoptosis; Caspase 3; DNA Fragmentation; Eosine Yellowish-(YS); Gene Expression Regulation; | 2015 |
Hydrogen-rich saline attenuates skin ischemia/reperfusion induced apoptosis via regulating Bax/Bcl-2 ratio and ASK-1/JNK pathway.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Free Tissue Flaps; Hydrogen; Ischemia; Male; MAP Kin | 2015 |
Antioxidants and K+ channel agonists versus hydrogen therapy during ex vivo lung perfusion†.
Topics: Antioxidants; Extracorporeal Circulation; Humans; Hydrogen; Ischemic Preconditioning; Lung Transplan | 2016 |
Molecular hydrogen attenuates hypoxia/reoxygenation injury of intrahepatic cholangiocytes by activating Nrf2 expression.
Topics: Animals; Apoptosis; Bile Ducts, Intrahepatic; Gene Silencing; Hydrogen; Liver Diseases; Male; NF-E2- | 2015 |
Effects of intraperitoneal hydrogen injection on nitric oxide synthase mRNA and malondialdehyde following limb ischemia-reperfusion in rabbits.
Topics: Animals; Disease Models, Animal; Extremities; Hydrogen; Injections, Intraperitoneal; Male; Malondial | 2015 |
Postconditioning with inhaled hydrogen promotes survival of retinal ganglion cells in a rat model of retinal ischemia/reperfusion injury.
Topics: Animals; Cell Survival; Disease Models, Animal; Hydrogen; Ischemic Postconditioning; Male; Rats; Rat | 2016 |
Protection of donor lung inflation in the setting of cold ischemia against ischemia-reperfusion injury with carbon monoxide, hydrogen, or both in rats.
Topics: Animals; Apoptosis; Blood Gas Analysis; Carbon Monoxide; Cold Ischemia; Drug Synergism; Hydrogen; In | 2016 |
Neuroprotective Effect of Hydrogen-Rich Saline in Global Cerebral Ischemia/Reperfusion Rats: Up-Regulated Tregs and Down-Regulated miR-21, miR-210 and NF-κB Expression.
Topics: Animals; Apoptosis; Brain Ischemia; Hippocampus; Hydrogen; Male; MicroRNAs; Neuroprotective Agents; | 2016 |
Inhalation of water electrolysis-derived hydrogen ameliorates cerebral ischemia-reperfusion injury in rats - A possible new hydrogen resource for clinical use.
Topics: Animals; Apoptosis; Brain; Brain Ischemia; Hydrogen; Male; Neurons; Neuroprotective Agents; Rats, Sp | 2016 |
Protective effect of hydrogen rich saline solution on experimental ovarian ischemia reperfusion model in rats.
Topics: Animals; Chi-Square Distribution; Female; Glutathione; Glutathione Transferase; Hydrogen; Male; Malo | 2017 |
The protective effects of hydrogen on HO-1 expression in the brainafter focal cerebral ischemia reperfusion in rats.
Topics: Animals; Brain Ischemia; Heme Oxygenase-1; Hydrogen; Malondialdehyde; Neuroprotective Agents; Rats; | 2016 |
Hydrogen inhalation ameliorates oxidative stress in transplantation induced intestinal graft injury.
Topics: Administration, Inhalation; Animals; Antioxidants; Gases; Hydrogen; Inflammation; Intestines; Male; | 2008 |
Hydrogen-rich saline reduces lung injury induced by intestinal ischemia/reperfusion in rats.
Topics: Animals; Cell Membrane; Hydrogen; Interleukin-1beta; Intestines; Lipid Peroxidation; Lung Injury; Ma | 2009 |
Hydrogen-rich saline protects against intestinal ischemia/reperfusion injury in rats.
Topics: Animals; Cytokines; Hydrogen; Inflammation; Inflammation Mediators; Infusions, Intravenous; Intestin | 2009 |
Hydrogen therapy may be an effective and specific novel treatment for acute radiation syndrome.
Topics: Acute Radiation Syndrome; Antioxidants; Apoptosis; Free Radicals; Gases; Humans; Hydrogen; Hydroxyl | 2010 |
Protection of the retina by rapid diffusion of hydrogen: administration of hydrogen-loaded eye drops in retinal ischemia-reperfusion injury.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Apoptosis; Biomarkers; Deoxyguanosine; Diffusion; D | 2010 |
The effects of hydrogen-rich saline on the contractile and structural changes of intestine induced by ischemia-reperfusion in rats.
Topics: Animals; Apoptosis; Cell Proliferation; Hydrogen; Jejunum; Male; Models, Animal; Muscle Contraction; | 2011 |
Hydrogen-rich saline solution attenuates renal ischemia-reperfusion injury.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Deoxyguanosine; Hydrogen; Kidney; Male; Rats; Rats, Wistar; Re | 2010 |
Oral administration of mannitol may be an effective treatment for ischemia-reperfusion injury.
Topics: Administration, Oral; Bacteria; Humans; Hydrogen; Intestines; Mannitol; Reperfusion Injury | 2010 |
Inhaled hydrogen gas therapy for prevention of lung transplant-induced ischemia/reperfusion injury in rats.
Topics: Administration, Inhalation; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blotting, | 2010 |
Beneficial effects of hydrogen gas against spinal cord ischemia-reperfusion injury in rabbits.
Topics: Animals; Antioxidants; Apoptosis; Cytokines; Hydrogen; In Situ Nick-End Labeling; Inflammation; Male | 2011 |
Hydrogen-rich saline protects against renal ischemia/reperfusion injury in rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cytokines; Deoxyguanosine; Disease Models, Animal; Hydrogen; K | 2011 |
The effect of hydrogen-rich saline on the brain of rats with transient ischemia.
Topics: Animals; Antioxidants; Caspase 3; Hippocampus; Hydrogen; Injections, Intraperitoneal; Interleukin-6; | 2011 |
Pectin and high-amylose maize starch increase caecal hydrogen production and relieve hepatic ischaemia-reperfusion injury in rats.
Topics: Amylose; Animals; Cecum; Fermentation; Glutathione; Hepatic Veno-Occlusive Disease; Hydrogen; Ischem | 2012 |
Hydrogen-rich saline attenuates lung ischemia-reperfusion injury in rabbits.
Topics: Animals; Hydrogen; Interleukin-8; Lung; Male; Oxidative Stress; Pulmonary Edema; Pulmonary Gas Excha | 2012 |
Effect of hydrogen gas on the survival rate of mice following global cerebral ischemia.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Inhalation; Animals; Body Water; Brain; Brain Ischemia; | 2012 |
The potential benefits of hydrogen-rich saline in ischemia and reperfusion injury.
Topics: Animals; Hydrogen; Lung; Male; Reperfusion Injury; Sodium Chloride | 2013 |
Inhaled hydrogen gas therapy for prevention of testicular ischemia/reperfusion injury in rats.
Topics: Administration, Inhalation; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Biomarkers | 2012 |
Protective effects of hydrogen rich saline solution on experimental testicular ischemia-reperfusion injury in rats.
Topics: Animals; Antioxidants; Apoptosis; Hydrogen; Male; Protective Agents; Rats; Rats, Sprague-Dawley; Rep | 2012 |
Hydrogen-rich University of Wisconsin solution attenuates renal cold ischemia-reperfusion injury.
Topics: Adenosine; Allopurinol; Animals; Apoptosis; Cold Temperature; Glutathione; Graft Survival; Hydrogen; | 2012 |
Hydrogen saline is protective for acute lung ischaemia/reperfusion injuries in rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acute Lung Injury; Animals; Biomarkers; Deoxyguanosine; Hydrogen; Male; | 2012 |
Profiling molecular changes induced by hydrogen treatment of lung allografts prior to procurement.
Topics: Animals; CCAAT-Enhancer-Binding Proteins; Hydrogen; Lung; Lung Transplantation; Male; Pulmonary Surf | 2012 |
Effect of hydrogen gas on the survival rate of mice following global cerebral ischemia (Shock 37(6), 645-652, 2012).
Topics: Animals; Brain Ischemia; Free Radical Scavengers; Hydrogen; Male; Mice; Reperfusion Injury | 2012 |
Letter to the editor on "Profiling molecular changes induced by hydrogen treatment of lung allografts prior to procurement".
Topics: Animals; Hydrogen; Lung; Lung Transplantation; Male; Pulmonary Surfactant-Associated Proteins; Reper | 2012 |
Hydrogen inhalation decreases lung graft injury in brain-dead donor rats.
Topics: Acute Lung Injury; Animals; Antioxidants; Apoptosis; Brain Death; Caspase 1; Hydrogen; In Situ Nick- | 2013 |
Role of Na+-H+ and Na+-Ca2+ exchange in hypoxia-related acute astrocyte death.
Topics: Acute Disease; Animals; Astrocytes; Brain; Calcium; Calcium Signaling; Cell Death; Cell Hypoxia; Cel | 2005 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
The hydrogen highway to reperfusion therapy.
Topics: Animals; Antioxidants; Cells, Cultured; Disease Models, Animal; Humans; Hydrogen; Membrane Potential | 2007 |
Inhalation of hydrogen gas suppresses hepatic injury caused by ischemia/reperfusion through reducing oxidative stress.
Topics: Administration, Inhalation; Animals; Hydrogen; Liver; Male; Mice; Oxidation-Reduction; Oxidative Str | 2007 |
Impact of female sex hormones on liver tissue lactic acidosis during ischemia.
Topics: Acidosis, Lactic; Animals; Estradiol; Female; Gonadal Steroid Hormones; Hydrogen; Lactic Acid; Liver | 2007 |
A one-dimensional (proton and phosphorus) and two-dimensional (proton) in vivo NMR spectroscopic study of reversible global cerebral ischemia.
Topics: Animals; Brain Ischemia; Hydrogen; Magnetic Resonance Spectroscopy; Male; Phosphorus Isotopes; Prose | 1996 |
Thermodiffusion for continuous quantification of hepatic microcirculation--validation and potential in liver transplantation.
Topics: Animals; Diffusion; Evaluation Studies as Topic; Hepatic Artery; Humans; Hydrogen; Liver; Liver Circ | 1999 |
Actions of adenosine on nitro blue tetrazolium deposition and surface pH during intestinal reperfusion injury.
Topics: Adenosine; Animals; Catalase; Hydrogen; Hydrogen-Ion Concentration; Intestines; Male; Nitroblue Tetr | 1990 |