Compounds > hydrogen
Page last updated: 2024-10-18

hydrogen and Inflammation

hydrogen has been researched along with Inflammation in 90 studies

Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"Molecular hydrogen treatment promotes functional outcomes after SAE in mice, which may be attributable to increasing beneficial bacteria, repressing harmful bacteria, and metabolic disorder, and reducing inflammation."9.69Effect of molecular hydrogen treatment on Sepsis-Associated encephalopathy in mice based on gut microbiota. ( Bai, Y; Chen, H; Dong, B; Han, Q; Li, Y; Luo, N; Yu, Y; Zhou, C, 2023)
" Therapeutic effects of H2-saline on joint inflammation were estimated by measuring serum biomarkers for RA, tumor necrosis factor-α (TNFα), interleukin-6 (IL-6), matrix metalloproteinase-3 (MMP-3), and urinary 8-hydroxydeoxyguanosine (8-OHdG)."9.19Therapeutic efficacy of infused molecular hydrogen in saline on rheumatoid arthritis: a randomized, double-blind, placebo-controlled pilot study. ( Hara, H; Hara, Y; Ishibashi, T; Koyanagi, S; Nagao, T; Naritomi, Y; Sakai, T; Sato, B; Shibata, S, 2014)
"The study highlights that continuous inhalation of hydrogen gas at a 2 % concentration for 24 h can be a potent intervention in the geriatric population for improving survival and physical activity by mitigating pulmonary inflammation and modulating senescence-related markers in aged mice with LPS-induced inflammation."8.31Attenuation of pulmonary damage in aged lipopolysaccharide-induced inflammation mice through continuous 2 % hydrogen gas inhalation: A potential therapeutic strategy for geriatric inflammation and survival. ( Ageta, K; Aokage, T; Iketani, M; Meng, Y; Naito, H; Nakao, A; Ohsawa, I; Seya, M, 2023)
"The aim of this study was to investigate the efficacy and underlying mechanism of high concentration of hydrogen on lipopolysaccharide (LPS)-induced acute lung injury (ALI)."8.12High concentration of hydrogen ameliorates lipopolysaccharide-induced acute lung injury in a sirt1-dependent manner. ( Du, J; Li, J; Li, R; Yan, X, 2022)
"Hydrogen-rich water partially alleviates inflammation, oxidative stress and intestinal flora dysbiosis in DSS-induced chronic UC mice."8.12Hydrogen-rich water partially alleviate inflammation, oxidative stress and intestinal flora dysbiosis in DSS-induced chronic ulcerative colitis mice. ( Ding, X; Song, L; Yan, H; Yang, L; Zhang, Y; Zhu, C, 2022)
"Many studies have demonstrated the therapeutic effects of hydrogen in pathological conditions such as inflammation; however, little is known about its prophylactic effects."8.12Prophylactic Instillation of Hydrogen-Rich Water Decreases Corneal Inflammation and Promotes Wound Healing by Activating Antioxidant Activity in a Rat Alkali Burn Model. ( Arima, T; Ikebukuro, T; Kasamatsu, M; Nakano, Y; Shimizu, A; Takahashi, H; Tobita, Y; Uchiyama, M, 2022)
"These results suggest that PINK1-mediated mitophagy plays a key role in the protective effects of hydrogen against cell injury in LPS-induced inflammation and CLP-induced acute lung injury."8.02Hydrogen alleviates cell damage and acute lung injury in sepsis via PINK1/Parkin-mediated mitophagy. ( Chen, H; Dong, B; Lin, H; Wang, Y; Xie, K; Yu, Y, 2021)
"We wish to investigate the acute effects of inhaled hydrogen on airway inflammation in patients with asthma and chronic obstructive pulmonary disease (COPD)."7.96Hydrogen gas (XEN) inhalation ameliorates airway inflammation in asthma and COPD patients. ( Bao, C; He, Y; Tian, X; Wang, ST; Xu, KF; Yang, Y; Zhang, T, 2020)
"Hydrogen-rich saline plays a protective role in ANP-induced AHI through inhibiting inflammation and apoptosis, involving JNK and p38 MAPK-dependent reactive oxygen species."7.83Hydrogen-Rich Saline Attenuates Acute Hepatic Injury in Acute Necrotizing Pancreatitis by Inhibiting Inflammation and Apoptosis, Involving JNK and p38 Mitogen-Activated Protein Kinase-dependent Reactive Oxygen Species. ( Chen, C; Deng, WH; Li, C; Mei, FC; Shi, Q; Wang, GR; Wang, P; Wang, WX; Yu, J; Zhao, KL; Zhao, L; Zuo, T, 2016)
"To investigate the role of Rho/ROCK signaling pathway in the protective effects of hydrogen gas (H2) on acute lung injury (ALI) in a mouse model of sepsis."7.83[Role of Rho/ROCK signaling pathway in the protective effects of hydrogen against acute lung injury in septic mice]. ( Liang, Y; Liu, L; Sun, Z; Yu, Y; Zhang, H, 2016)
"Luminal injection of hydrogen-rich solution can reduce oxidative stress and consequently ameliorate ischemic-reperfusion injury."7.81Luminal injection of hydrogen-rich solution attenuates intestinal ischemia-reperfusion injury in rats. ( Cai, S; Kasahara, M; Kurokawa, R; Li, XK; Liu, C; Nakazawa, A; Sakamoto, S; Shigeta, T; Uemoto, S, 2015)
"Hydrogen can attenuate severe burn-induced early AKI; the mechanisms of protection include the inhibition of oxidative stress induced apoptosis and inflammation, which may be mediated by regulation of the MAPKs, Akt and NF-κB signalling pathways."7.81Effects of hydrogen-rich saline on early acute kidney injury in severely burned rats by suppressing oxidative stress induced apoptosis and inflammation. ( Fang, Q; Guo, SX; Han, CM; Hu, XL; Jin, YY; Wang, XG; You, CG, 2015)
"Recent evidence suggests that molecular hydrogen has therapeutic value for disease states that involve inflammation."7.78Hydrogen-supplemented drinking water protects cardiac allografts from inflammation-associated deterioration. ( Bermudez, CA; Kawamura, T; Masutani, K; Nakao, A; Noda, K; Shigemura, N; Sun, X; Tanaka, Y; Toyoda, Y; Wang, Y, 2012)
"This study is to examine if hydrogen-rich saline reduced amyloid-beta (Aβ) induced neural inflammation and oxidative stress in a rat model by attenuation of activation of JNK and NF-κB."7.77Hydrogen-rich saline reduces oxidative stress and inflammation by inhibit of JNK and NF-κB activation in a rat model of amyloid-beta-induced Alzheimer's disease. ( Cao, YP; Li, J; Liu, Q; Sun, XJ; Wang, C; Yang, R; Zhang, JH, 2011)
"Pancreatitis is an inflammatory disease of the pancreas characterized by acinar cell injury and is associated with the abnormal release of trypsin, which results in high mortality due to systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS)."6.72Recent advances in studies of molecular hydrogen in the treatment of pancreatitis. ( Li, G; Li, Y; Suo, L; Zhang, J, 2021)
"Heart failure is the end stage of various heart diseases such as ischemic heart disease, dilated cardiomyopathy, valvular heart disease, congenital heart disease, and hypertensive myocardial damage."6.61Advances in research on treatment of heart failure with nitrosyl hydrogen. ( An, J; Deng, Y; Guo, Y; Wang, J; Wu, L; Xu, J, 2019)
"Diabetic stroke is associated with a higher risk of death and worse neural function."5.91Molecular Hydrogen Mediates Neurorestorative Effects After Stroke in Diabetic Rats: the TLR4/NF-κB Inflammatory Pathway. ( Lai, PC; Li, TT; Li, WZ; Sun, LY; Wan, Q; Yang, WC; Zhang, X; Zhang, YR, 2023)
"Hydrogen has neuroprotective effects against brain-related diseases."5.72Hydrogen Attenuated Inflammation Response and Oxidative in Hypoxic Ischemic Encephalopathy via Nrf2 Mediated the Inhibition of NLRP3 and NF-κB. ( Han, K; Hu, Y; Wang, P, 2022)
"Molecular hydrogen treatment promotes functional outcomes after SAE in mice, which may be attributable to increasing beneficial bacteria, repressing harmful bacteria, and metabolic disorder, and reducing inflammation."5.69Effect of molecular hydrogen treatment on Sepsis-Associated encephalopathy in mice based on gut microbiota. ( Bai, Y; Chen, H; Dong, B; Han, Q; Li, Y; Luo, N; Yu, Y; Zhou, C, 2023)
"Hydrogen treatment downregulated the expression of necroptosis-related proteins, such as MLKL, phosphorylated-MLKL, and RIPK3 in hippocampus, and further protected neurons and astrocytes from necroptosis which was here first verified to occur in status epilepticus."5.51Hydrogen Alleviates Necroptosis and Cognitive Deficits in Lithium-Pilocarpine Model of Status Epilepticus. ( Gao, F; Jia, N; Jia, R; Jiang, W; Jiang, Y; Li, R; Liu, Z; Wang, L; Wu, S; Yang, F; Zhang, H; Zhang, S; Zhang, Z; Zhao, J, 2019)
"At 6, 24 and 48 h post-intracerebral hemorrhage, animals showed brain edema and neurologic deficits, accompanied by up-regulation of TNF-a, IL-b, BDNF, and caspase-3, which is indicative of neuroinflammation, neuroprotection, and apoptosis."5.48Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model. ( Choi, KS; Do, SH; Hwang, SJ; Kim, HJ; Yi, HJ, 2018)
" CPF combined with bacterial infection is a potential problem for children during their childhood development."5.48Evaluation of the effects of chlorpyrifos combined with lipopolysaccharide stress on neuroinflammation and spatial memory in neonatal rats. ( Bing, G; Dai, H; Deng, Y; Tian, J; Wang, P; Zhang, C; Zhao, L; Zhao, M, 2018)
"Hydrogen gas treatment inhibited LPS-induced pulmonary early and late NF-κB activation."5.38Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and apoptosis. ( Chen, H; Gong, G; Han, H; Hou, L; Huang, Y; Li, J; Wang, G; Xie, K; Yu, Y; Zheng, L, 2012)
"Spinal cord ischemia was induced by infrarenal aortic occlusion for 20 min in male New Zealand white rabbits."5.37Beneficial effects of hydrogen gas against spinal cord ischemia-reperfusion injury in rabbits. ( Dong, H; Gong, G; Huang, Y; Li, J; Wang, G; Xie, K; Xiong, L; Xu, N; Yu, Y, 2011)
"Sepsis/multiple organ dysfunction syndrome is the leading cause of death in critically ill patients."5.36Hydrogen gas improves survival rate and organ damage in zymosan-induced generalized inflammation model. ( Hou, L; Liu, W; Pei, Y; Wang, G; Xie, K; Xiong, L; Yu, Y; Zhang, Z, 2010)
"Hydrogen gas was reported to reduce reactive oxygen species and alleviate cerebral, myocardial and hepatic ischemia/reperfusion (I/R) injuries."5.35Hydrogen-rich saline protects against intestinal ischemia/reperfusion injury in rats. ( Cai, J; Li, Y; Liu, W; Mao, Y; Sun, P; Sun, X; Yuan, H; Zhang, JH; Zheng, X, 2009)
"Because hydrogen therapy has been found beneficial for the treatment of inflammation, ischemia-reperfusion injury, and oxidative stress in humans, it seems useful to evaluate the effects of exogenously administered hydrogen as an element in the immediate management of sports-related soft tissue injuries."5.19Effectiveness of oral and topical hydrogen for sports-related soft tissue injuries. ( Calleja-Gonzalez, J; Hoffman, JR; Ostojic, SM; Vukomanovic, B, 2014)
" Therapeutic effects of H2-saline on joint inflammation were estimated by measuring serum biomarkers for RA, tumor necrosis factor-α (TNFα), interleukin-6 (IL-6), matrix metalloproteinase-3 (MMP-3), and urinary 8-hydroxydeoxyguanosine (8-OHdG)."5.19Therapeutic efficacy of infused molecular hydrogen in saline on rheumatoid arthritis: a randomized, double-blind, placebo-controlled pilot study. ( Hara, H; Hara, Y; Ishibashi, T; Koyanagi, S; Nagao, T; Naritomi, Y; Sakai, T; Sato, B; Shibata, S, 2014)
"Age, APACHE score at ICU admission, neurological disease, sepsis and duration of mechanical ventilation were all independent risk factors for the development of delirium in ICU patients."4.40Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023)
"Lung inflation using hydrogen during CIP may improve donor lung quality by mitigating mitochondrial structural anomalies, enhancing mitochondrial function, and alleviating oxidative stress, inflammation, and apoptosis, which may be achieved through activation of the Nrf2/HO-1 pathway."4.31Inflation using hydrogen improves donor lung quality by regulating mitochondrial function during cold ischemia phase. ( Duan, L; Li, Z; Quan, L; Zhang, G; Zhang, M; Zheng, B; Zhou, H, 2023)
"The study highlights that continuous inhalation of hydrogen gas at a 2 % concentration for 24 h can be a potent intervention in the geriatric population for improving survival and physical activity by mitigating pulmonary inflammation and modulating senescence-related markers in aged mice with LPS-induced inflammation."4.31Attenuation of pulmonary damage in aged lipopolysaccharide-induced inflammation mice through continuous 2 % hydrogen gas inhalation: A potential therapeutic strategy for geriatric inflammation and survival. ( Ageta, K; Aokage, T; Iketani, M; Meng, Y; Naito, H; Nakao, A; Ohsawa, I; Seya, M, 2023)
"Many studies have demonstrated the therapeutic effects of hydrogen in pathological conditions such as inflammation; however, little is known about its prophylactic effects."4.12Prophylactic Instillation of Hydrogen-Rich Water Decreases Corneal Inflammation and Promotes Wound Healing by Activating Antioxidant Activity in a Rat Alkali Burn Model. ( Arima, T; Ikebukuro, T; Kasamatsu, M; Nakano, Y; Shimizu, A; Takahashi, H; Tobita, Y; Uchiyama, M, 2022)
"The aim of this study was to investigate the efficacy and underlying mechanism of high concentration of hydrogen on lipopolysaccharide (LPS)-induced acute lung injury (ALI)."4.12High concentration of hydrogen ameliorates lipopolysaccharide-induced acute lung injury in a sirt1-dependent manner. ( Du, J; Li, J; Li, R; Yan, X, 2022)
" In the past 10 years, gas medical studies have found that both hydrogen molecules and oxygen molecules have protective effects on acute lung injury by improving inflammatory reactions and hypoxia, respectively."4.12Hydrogen-rich and hyperoxygenate saline inhibits lipopolysaccharide-induced lung injury through mediating NF-κB/NLRP3 signaling pathway in C57BL/6 mice. ( Cao, K; Fan, Y; Feng, Z; Liu, J; Wang, J; Xu, H, 2022)
"Hydrogen-rich water partially alleviates inflammation, oxidative stress and intestinal flora dysbiosis in DSS-induced chronic UC mice."4.12Hydrogen-rich water partially alleviate inflammation, oxidative stress and intestinal flora dysbiosis in DSS-induced chronic ulcerative colitis mice. ( Ding, X; Song, L; Yan, H; Yang, L; Zhang, Y; Zhu, C, 2022)
" Since molecular hydrogen is known to preferentially remove cytotoxic hydroxyl radicals and peroxynitrites, and to prevent cell and tissue damage, we here examined whether electrolyzed hydrogen water (EHW) enriched with molecular hydrogen and reactive hydrogen storing platinum nanoparticles dissolved from an electrode could alleviate oxidative stress and inflammation induced by continuous stress challenges."4.02Alleviation of the chronic stress response attributed to the antioxidant and anti-inflammatory effects of electrolyzed hydrogen water. ( Cui, Y; Hu, D; Kabayama, S; Li, D; Neyama, H; Ochi, Y; Okauchi, T; Shigeta, M; Watanabe, Y, 2021)
"These results suggest that PINK1-mediated mitophagy plays a key role in the protective effects of hydrogen against cell injury in LPS-induced inflammation and CLP-induced acute lung injury."4.02Hydrogen alleviates cell damage and acute lung injury in sepsis via PINK1/Parkin-mediated mitophagy. ( Chen, H; Dong, B; Lin, H; Wang, Y; Xie, K; Yu, Y, 2021)
"We wish to investigate the acute effects of inhaled hydrogen on airway inflammation in patients with asthma and chronic obstructive pulmonary disease (COPD)."3.96Hydrogen gas (XEN) inhalation ameliorates airway inflammation in asthma and COPD patients. ( Bao, C; He, Y; Tian, X; Wang, ST; Xu, KF; Yang, Y; Zhang, T, 2020)
"High concentrations of hydrogen could ameliorate pulmonary dysfunction, airway mucus hypersecretion, oxidation damage, and inflammation response in rats exposed to concentrated ambient PM2."3.91Hydrogen ameliorates lung injury in a rat model of subacute exposure to concentrated ambient PM2.5 via Aryl hydrocarbon receptor. ( Chao, L; Duan, E; Feng, S; Li, H; Li, R; Shi, X; Yan, X; Zhang, H; Zhang, W; Zhao, Y; Zhong, X, 2019)
" Many studies have found that molecular hydrogen (H2) has significant neuroprotection against acute and chronic neurological injury by regulating inflammation and apoptosis."3.85Molecular hydrogen inhalation attenuates postoperative cognitive impairment in rats. ( Chang, L; Liu, H; Xie, K; Xin, Y; Zhang, P, 2017)
"To investigate the role of Rho/ROCK signaling pathway in the protective effects of hydrogen gas (H2) on acute lung injury (ALI) in a mouse model of sepsis."3.83[Role of Rho/ROCK signaling pathway in the protective effects of hydrogen against acute lung injury in septic mice]. ( Liang, Y; Liu, L; Sun, Z; Yu, Y; Zhang, H, 2016)
"Hydrogen-rich saline plays a protective role in ANP-induced AHI through inhibiting inflammation and apoptosis, involving JNK and p38 MAPK-dependent reactive oxygen species."3.83Hydrogen-Rich Saline Attenuates Acute Hepatic Injury in Acute Necrotizing Pancreatitis by Inhibiting Inflammation and Apoptosis, Involving JNK and p38 Mitogen-Activated Protein Kinase-dependent Reactive Oxygen Species. ( Chen, C; Deng, WH; Li, C; Mei, FC; Shi, Q; Wang, GR; Wang, P; Wang, WX; Yu, J; Zhao, KL; Zhao, L; Zuo, T, 2016)
"Luminal injection of hydrogen-rich solution can reduce oxidative stress and consequently ameliorate ischemic-reperfusion injury."3.81Luminal injection of hydrogen-rich solution attenuates intestinal ischemia-reperfusion injury in rats. ( Cai, S; Kasahara, M; Kurokawa, R; Li, XK; Liu, C; Nakazawa, A; Sakamoto, S; Shigeta, T; Uemoto, S, 2015)
" Hydrogen has been reported to alleviate injury triggered by ischaemia/reperfusion and burns in various organs by selectively quenching oxygen free radicals."3.81Beneficial effects of hydrogen-rich saline on early burn-wound progression in rats. ( Fang, Q; Guo, SX; Han, CM; Hu, XL; Jin, YY; Wang, XG; You, CG, 2015)
" Therefore, the objective of the present study was to assess whether H2, a ROS scavenger, has a therapeutic effect on psoriasis-associated inflammation by reducing hydroxyl radicals or peroxynitrite in the immunogenic psoriasis cascade."3.81Improvement of psoriasis-associated arthritis and skin lesions by treatment with molecular hydrogen: A report of three cases. ( Hara, H; Hara, Y; Ichikawa, M; Ishibashi, T; Iwamoto, Y; Koyanagi, S; Nagao, T; Nakashima, Y; Naritomi, Y; Okazaki, K; Sato, B; Shibata, S, 2015)
"Hydrogen can attenuate severe burn-induced early AKI; the mechanisms of protection include the inhibition of oxidative stress induced apoptosis and inflammation, which may be mediated by regulation of the MAPKs, Akt and NF-κB signalling pathways."3.81Effects of hydrogen-rich saline on early acute kidney injury in severely burned rats by suppressing oxidative stress induced apoptosis and inflammation. ( Fang, Q; Guo, SX; Han, CM; Hu, XL; Jin, YY; Wang, XG; You, CG, 2015)
"Recent evidence suggests that molecular hydrogen has therapeutic value for disease states that involve inflammation."3.78Hydrogen-supplemented drinking water protects cardiac allografts from inflammation-associated deterioration. ( Bermudez, CA; Kawamura, T; Masutani, K; Nakao, A; Noda, K; Shigemura, N; Sun, X; Tanaka, Y; Toyoda, Y; Wang, Y, 2012)
"This study is to examine if hydrogen-rich saline reduced amyloid-beta (Aβ) induced neural inflammation and oxidative stress in a rat model by attenuation of activation of JNK and NF-κB."3.77Hydrogen-rich saline reduces oxidative stress and inflammation by inhibit of JNK and NF-κB activation in a rat model of amyloid-beta-induced Alzheimer's disease. ( Cao, YP; Li, J; Liu, Q; Sun, XJ; Wang, C; Yang, R; Zhang, JH, 2011)
"Pancreatitis is an inflammatory disease of the pancreas characterized by acinar cell injury and is associated with the abnormal release of trypsin, which results in high mortality due to systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome (MODS)."2.72Recent advances in studies of molecular hydrogen in the treatment of pancreatitis. ( Li, G; Li, Y; Suo, L; Zhang, J, 2021)
"Heart failure is the end stage of various heart diseases such as ischemic heart disease, dilated cardiomyopathy, valvular heart disease, congenital heart disease, and hypertensive myocardial damage."2.61Advances in research on treatment of heart failure with nitrosyl hydrogen. ( An, J; Deng, Y; Guo, Y; Wang, J; Wu, L; Xu, J, 2019)
"Diabetic stroke is associated with a higher risk of death and worse neural function."1.91Molecular Hydrogen Mediates Neurorestorative Effects After Stroke in Diabetic Rats: the TLR4/NF-κB Inflammatory Pathway. ( Lai, PC; Li, TT; Li, WZ; Sun, LY; Wan, Q; Yang, WC; Zhang, X; Zhang, YR, 2023)
"Hydrogen Therapy (HT) has gained scientists' attention with the proven clinical ability to attenuate chronic inflammation, diminish oxidative stress, restrict apoptosis, minimize cellular injury, and refine tissue functioning."1.72Narrative on Hydrogen Therapy and its Clinical Applications: Safety and Efficacy. ( Ahmad, A; Ahmed, N; Baig, AA; Bilal, M; Chopra, H; Hassan, M; Hussain, M; Kamal, MA; Khaliq, M; Putnala, SK; Rachamalla, M; Saeed, MU; Tahir, Z, 2022)
"For example, coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global pandemic."1.72Molecular hydrogen is a promising therapeutic agent for pulmonary disease. ( Fu, Z; Zhang, J, 2022)
"Hydrogen has neuroprotective effects against brain-related diseases."1.72Hydrogen Attenuated Inflammation Response and Oxidative in Hypoxic Ischemic Encephalopathy via Nrf2 Mediated the Inhibition of NLRP3 and NF-κB. ( Han, K; Hu, Y; Wang, P, 2022)
"Hydrogen treatment downregulated the expression of necroptosis-related proteins, such as MLKL, phosphorylated-MLKL, and RIPK3 in hippocampus, and further protected neurons and astrocytes from necroptosis which was here first verified to occur in status epilepticus."1.51Hydrogen Alleviates Necroptosis and Cognitive Deficits in Lithium-Pilocarpine Model of Status Epilepticus. ( Gao, F; Jia, N; Jia, R; Jiang, W; Jiang, Y; Li, R; Liu, Z; Wang, L; Wu, S; Yang, F; Zhang, H; Zhang, S; Zhang, Z; Zhao, J, 2019)
"The results showed that neuropathic pain stimulated activation of inflammasome NLRP3 and autophagy pathway in the microglial cells of the spinal cord."1.51Hydrogen-rich Saline Alleviated the Hyperpathia and Microglia Activation via Autophagy Mediated Inflammasome Inactivation in Neuropathic Pain Rats. ( Chen, H; Meng, X; Wang, Y; Xie, K; Yu, Y; Zhou, C, 2019)
"Here, we determined the effect of HRS in experimental autoimmune encephalomyelitis (EAE), which is a generally accepted model of the immuno-pathogenic mechanisms underlying MS."1.51Hydrogen-Rich Saline Ameliorates Experimental Autoimmune Encephalomyelitis in C57BL/6 Mice Via the Nrf2-ARE Signaling Pathway. ( Dong, F; Guo, R; Liu, Y; Qu, X; Wu, X; Yao, R; Zhang, Y, 2019)
" CPF combined with bacterial infection is a potential problem for children during their childhood development."1.48Evaluation of the effects of chlorpyrifos combined with lipopolysaccharide stress on neuroinflammation and spatial memory in neonatal rats. ( Bing, G; Dai, H; Deng, Y; Tian, J; Wang, P; Zhang, C; Zhao, L; Zhao, M, 2018)
"At 6, 24 and 48 h post-intracerebral hemorrhage, animals showed brain edema and neurologic deficits, accompanied by up-regulation of TNF-a, IL-b, BDNF, and caspase-3, which is indicative of neuroinflammation, neuroprotection, and apoptosis."1.48Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model. ( Choi, KS; Do, SH; Hwang, SJ; Kim, HJ; Yi, HJ, 2018)
"Sepsis is common in intensive care units (ICU) and is associated with high mortality."1.42Hydrogen-Rich Saline Attenuates Lipopolysaccharide-Induced Heart Dysfunction by Restoring Fatty Acid Oxidation in Rats by Mitigating C-Jun N-Terminal Kinase Activation. ( Liu, L; Tao, B; Tong, D; Wang, N; Wang, W; Zhang, J, 2015)
"Hyperoxic lung injury is a major concern in critically ill patients who receive high concentrations of oxygen to treat lung diseases."1.39Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo. ( Billiar, TR; Huang, CS; Kawamura, T; Kensler, TW; Masutani, K; Nakao, A; Noda, K; Okumura, M; Peng, X; Shigemura, N; Takahashi, T; Tanaka, Y; Toyoda, Y; Wakabayashi, N, 2013)
"Hydrogen gas treatment inhibited LPS-induced pulmonary early and late NF-κB activation."1.38Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and apoptosis. ( Chen, H; Gong, G; Han, H; Hou, L; Huang, Y; Li, J; Wang, G; Xie, K; Yu, Y; Zheng, L, 2012)
"Hydrogen-rich saline treatment significantly reduced the level of degraded myelin basic protein, decreased the expression of ionized calcium-binding adapter molecule 1, Iba1, a microglial marker, reduced DNA oxidation, and suppressed proinflammatory cytokine interleukin-1β, interleukin-6, and tumor necrosis factor-α in the cortex and hippocampal tissues when compared with those in normal saline-treated rats."1.37Hydrogen-rich saline reduces delayed neurologic sequelae in experimental carbon monoxide toxicity. ( Cai, J; Sun, Q; Sun, XJ; Tao, H; Zhang, JH; Zhang, W; Zhou, J, 2011)
"Spinal cord ischemia was induced by infrarenal aortic occlusion for 20 min in male New Zealand white rabbits."1.37Beneficial effects of hydrogen gas against spinal cord ischemia-reperfusion injury in rabbits. ( Dong, H; Gong, G; Huang, Y; Li, J; Wang, G; Xie, K; Xiong, L; Xu, N; Yu, Y, 2011)
"Sepsis/multiple organ dysfunction syndrome is the leading cause of death in critically ill patients."1.36Hydrogen gas improves survival rate and organ damage in zymosan-induced generalized inflammation model. ( Hou, L; Liu, W; Pei, Y; Wang, G; Xie, K; Xiong, L; Yu, Y; Zhang, Z, 2010)
"Hydrogen treatment resulted in significantly improved gastrointestinal transit, as well as jejunal smooth muscle contractility in response to bethanechol."1.35Hydrogen inhalation ameliorates oxidative stress in transplantation induced intestinal graft injury. ( Bauer, AJ; Billiar, TR; Buchholz, BM; Kaczorowski, DJ; McCurry, KR; Nakao, A; Sugimoto, R; Wang, Y; Yang, R, 2008)
"Hydrogen gas was reported to reduce reactive oxygen species and alleviate cerebral, myocardial and hepatic ischemia/reperfusion (I/R) injuries."1.35Hydrogen-rich saline protects against intestinal ischemia/reperfusion injury in rats. ( Cai, J; Li, Y; Liu, W; Mao, Y; Sun, P; Sun, X; Yuan, H; Zhang, JH; Zheng, X, 2009)

Research

Studies (90)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (7.78)29.6817
2010's48 (53.33)24.3611
2020's35 (38.89)2.80

Authors

AuthorsStudies
Mostafa, DM1
Ammar, NM1
Abd El-Alim, SH1
Kassem, AA1
Hussein, RA1
Awad, G1
El-Awdan, SA1
Nagato, LK1
Lourenço, MG1
Cadete, RA1
Leite-Júnior, JH1
Koatz, VL1
Rocco, PR1
Faffe, DS1
Zin, WA1
Du, J1
Li, J11
Li, R4
Yan, X3
Song, L1
Zhang, Y15
Zhu, C1
Ding, X1
Yang, L1
Yan, H1
Hu, Y2
Wang, P5
Han, K1
Fu, Z1
Zhang, J8
Luo, P1
Ding, Y1
He, Y4
Chen, D6
He, Q1
Huang, Z3
Huang, S2
Lei, W1
Li, C4
Cao, Y1
Kohei, F1
Hao, H1
Peng, G1
Cheng, C1
Ye, J2
Fan, Y4
Wang, J10
Feng, Z1
Cao, K1
Liu, J5
Xu, H4
Otani, N1
Tomita, K1
Kobayashi, Y1
Kuroda, K1
Koyama, Y1
Kobayashi, H2
Kubo, T1
Yang, WC1
Li, TT1
Wan, Q1
Zhang, X11
Sun, LY1
Zhang, YR1
Lai, PC1
Li, WZ1
Ahmad, A1
Baig, AA1
Hussain, M1
Saeed, MU1
Bilal, M1
Ahmed, N1
Chopra, H1
Hassan, M1
Rachamalla, M1
Putnala, SK1
Khaliq, M1
Tahir, Z1
Kamal, MA1
Kasamatsu, M1
Arima, T1
Ikebukuro, T1
Nakano, Y1
Tobita, Y1
Uchiyama, M1
Shimizu, A1
Takahashi, H1
Hu, R1
Dai, C1
Dong, C3
Ding, L1
Huang, H5
Chen, Y2
Zhang, B3
Hu, D3
Huang, T1
Shigeta, M2
Ochi, Y2
Kabayama, S2
Watanabe, Y2
Cui, Y3
Han, Q3
Bai, Y3
Zhou, C6
Dong, B5
Li, Y11
Luo, N3
Chen, H7
Yu, Y12
Duan, L1
Quan, L2
Zheng, B2
Li, Z5
Zhang, G4
Zhang, M4
Zhou, H4
Rathod, DK1
Chakravarthy, C1
Suryadevara, SS1
Patil, RS1
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Clinical Trials (11)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Perioperative Hydrogen Inhalation on Post-operative Pain and Inflammation Cytokines[NCT05476575]32 participants (Anticipated)Interventional2021-10-28Recruiting
Efficacy and Safety of Hydrogen Inhalation on Bronchiectasis (HYBRID): A Randomized, Multi-center, Double-blind, Parallel-group Study[NCT02765295]120 participants (Anticipated)Interventional2016-06-01Recruiting
Adjuvant Therapy for Severe COPD Patients in the Stable Phase by an Oxyhydrogen Generator With Nebulizer: A Multi-centric, Randomized, Parallel-control and Double-blinded Clinic Study[NCT02850185]170 participants (Anticipated)Interventional2016-07-15Recruiting
Adjuvant Therapy for Severe Asthma by an Oxyhydrogen Generator With Nebulizer: A Multi-centric, Randomized, Parallel-control and Double-blinded Clinic Study on Effectiveness and Safety[NCT02883582]150 participants (Anticipated)Interventional2016-08-31Recruiting
Mechanisms Linking Dietary Fiber, the Microbiome and Satiety[NCT04611217]88 participants (Anticipated)Interventional2021-04-22Recruiting
Over-night Metabolic Effects of Legumes[NCT01706042]16 participants (Actual)Interventional2010-02-28Completed
Hydrogen-Rich Celsior Solution Improve the Quality of Aging DBD Grafts in Liver/Kidney Transplantation: Prospective, Randomized Clinical Trial[NCT02613195]Phase 320 participants (Anticipated)Interventional2016-01-31Not yet recruiting
[NCT01759498]Phase 236 participants (Actual)Interventional2012-12-31Completed
Hydrotherapy With Hydrogen-rich Water Compared With RICE Protocol Following Acute Ankle Sprain in Professional Athletes: a Randomized Non-inferiority Trial[NCT04167202]18 participants (Actual)Interventional2019-12-01Completed
Healthy Effects of an Innovative Probiotic Pasta[NCT02236533]40 participants (Actual)Interventional2014-03-31Completed
Evaluation of the Daily Intake of 0.5 L of Water Saturated With Molecular Hydrogen for 21 Days in COVID-19 Patients Treated in Ambulatory Care. Double-blind, Randomized, Comparative Study[NCT04716985]700 participants (Actual)Interventional2021-01-22Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

11 reviews available for hydrogen and Inflammation

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
Recent advances in studies of molecular hydrogen in the treatment of pancreatitis.
    Life sciences, 2021, Jan-01, Volume: 264

    Topics: Animals; Antioxidants; Apoptosis; Autophagy; Cell Death; Endoplasmic Reticulum Stress; Humans; Hydro

2021
Recent Advances in Molecular Hydrogen Research Reducing Exercise-Induced Oxidative Stress and Inflammation.
    Current pharmaceutical design, 2021, Volume: 27, Issue:5

    Topics: Animals; Antioxidants; Humans; Hydrogen; Inflammation; Oxidation-Reduction; Oxidative Stress

2021
Potential Therapeutic Applications of Hydrogen in Chronic Inflammatory Diseases: Possible Inhibiting Role on Mitochondrial Stress.
    International journal of molecular sciences, 2021, Mar-04, Volume: 22, Issue:5

    Topics: Animals; Chronic Disease; COVID-19; Humans; Hydrogen; Inflammation; Mitochondria; NLR Family, Pyrin

2021
Protective effects of molecular hydrogen on lung injury from lung transplantation.
    Experimental biology and medicine (Maywood, N.J.), 2021, Volume: 246, Issue:12

    Topics: Animals; Humans; Hydrogen; Inflammation; Lung; Lung Injury; Lung Transplantation; Oxidative Stress

2021
Molecular Hydrogen as a Novel Protective Agent against Pre-Symptomatic Diseases.
    International journal of molecular sciences, 2021, Jul-05, Volume: 22, Issue:13

    Topics: Alzheimer Disease; Animals; Asymptomatic Diseases; Chronic Disease; Diabetes Mellitus, Type 2; Free

2021
Hydrogen Therapy in Cardiovascular and Metabolic Diseases: from Bench to Bedside.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 47, Issue:1

    Topics: Adaptive Immunity; Animals; Apoptosis; Cardiovascular Diseases; Humans; Hydrogen; Inflammation; Meta

2018
Advances in research on treatment of heart failure with nitrosyl hydrogen.
    Heart failure reviews, 2019, Volume: 24, Issue:6

    Topics: Calcium; Cardiotonic Agents; Heart Failure; Humans; Hydrogen; Hypertrophy; Inflammation; Myocardial

2019
Molecular hydrogen: new antioxidant and anti-inflammatory therapy for rheumatoid arthritis and related diseases.
    Current pharmaceutical design, 2013, Volume: 19, Issue:35

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arthritis, Rheumatoid; Atherosclerosis; Humans; Hyd

2013
Local cortisol/corticosterone activation in skin physiology and pathology.
    Journal of dermatological science, 2016, Volume: 84, Issue:1

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aging; Ani

2016

Trials

6 trials available for hydrogen and Inflammation

ArticleYear
Effect of molecular hydrogen treatment on Sepsis-Associated encephalopathy in mice based on gut microbiota.
    CNS neuroscience & therapeutics, 2023, Volume: 29, Issue:2

    Topics: Animals; Brain; Gastrointestinal Microbiome; Hydrogen; Inflammation; Male; Mice; Sepsis; Sepsis-Asso

2023
Effect of molecular hydrogen treatment on Sepsis-Associated encephalopathy in mice based on gut microbiota.
    CNS neuroscience & therapeutics, 2023, Volume: 29, Issue:2

    Topics: Animals; Brain; Gastrointestinal Microbiome; Hydrogen; Inflammation; Male; Mice; Sepsis; Sepsis-Asso

2023
Effect of molecular hydrogen treatment on Sepsis-Associated encephalopathy in mice based on gut microbiota.
    CNS neuroscience & therapeutics, 2023, Volume: 29, Issue:2

    Topics: Animals; Brain; Gastrointestinal Microbiome; Hydrogen; Inflammation; Male; Mice; Sepsis; Sepsis-Asso

2023
Effect of molecular hydrogen treatment on Sepsis-Associated encephalopathy in mice based on gut microbiota.
    CNS neuroscience & therapeutics, 2023, Volume: 29, Issue:2

    Topics: Animals; Brain; Gastrointestinal Microbiome; Hydrogen; Inflammation; Male; Mice; Sepsis; Sepsis-Asso

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
    The Egyptian journal of chest diseases and tuberculosis, 2016, Volume: 65, Issue:1

    Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P

2016
Effects of a brown beans evening meal on metabolic risk markers and appetite regulating hormones at a subsequent standardized breakfast: a randomized cross-over study.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Appetite; Biomarkers; Blood Glucose; Breakfast; Breath Tests; Cross-Over Studies; Diet; Dietary Carb

2013
Effects of a brown beans evening meal on metabolic risk markers and appetite regulating hormones at a subsequent standardized breakfast: a randomized cross-over study.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Appetite; Biomarkers; Blood Glucose; Breakfast; Breath Tests; Cross-Over Studies; Diet; Dietary Carb

2013
Effects of a brown beans evening meal on metabolic risk markers and appetite regulating hormones at a subsequent standardized breakfast: a randomized cross-over study.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Appetite; Biomarkers; Blood Glucose; Breakfast; Breath Tests; Cross-Over Studies; Diet; Dietary Carb

2013
Effects of a brown beans evening meal on metabolic risk markers and appetite regulating hormones at a subsequent standardized breakfast: a randomized cross-over study.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Appetite; Biomarkers; Blood Glucose; Breakfast; Breath Tests; Cross-Over Studies; Diet; Dietary Carb

2013
Therapeutic efficacy of infused molecular hydrogen in saline on rheumatoid arthritis: a randomized, double-blind, placebo-controlled pilot study.
    International immunopharmacology, 2014, Volume: 21, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Deoxyguanosine;

2014
Therapeutic efficacy of infused molecular hydrogen in saline on rheumatoid arthritis: a randomized, double-blind, placebo-controlled pilot study.
    International immunopharmacology, 2014, Volume: 21, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Deoxyguanosine;

2014
Therapeutic efficacy of infused molecular hydrogen in saline on rheumatoid arthritis: a randomized, double-blind, placebo-controlled pilot study.
    International immunopharmacology, 2014, Volume: 21, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Deoxyguanosine;

2014
Therapeutic efficacy of infused molecular hydrogen in saline on rheumatoid arthritis: a randomized, double-blind, placebo-controlled pilot study.
    International immunopharmacology, 2014, Volume: 21, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Deoxyguanosine;

2014
Effectiveness of oral and topical hydrogen for sports-related soft tissue injuries.
    Postgraduate medicine, 2014, Volume: 126, Issue:5

    Topics: Adult; Athletes; Biomarkers; C-Reactive Protein; Drug Administration Routes; Humans; Hydrogen; Infla

2014
Effectiveness of oral and topical hydrogen for sports-related soft tissue injuries.
    Postgraduate medicine, 2014, Volume: 126, Issue:5

    Topics: Adult; Athletes; Biomarkers; C-Reactive Protein; Drug Administration Routes; Humans; Hydrogen; Infla

2014
Effectiveness of oral and topical hydrogen for sports-related soft tissue injuries.
    Postgraduate medicine, 2014, Volume: 126, Issue:5

    Topics: Adult; Athletes; Biomarkers; C-Reactive Protein; Drug Administration Routes; Humans; Hydrogen; Infla

2014
Effectiveness of oral and topical hydrogen for sports-related soft tissue injuries.
    Postgraduate medicine, 2014, Volume: 126, Issue:5

    Topics: Adult; Athletes; Biomarkers; C-Reactive Protein; Drug Administration Routes; Humans; Hydrogen; Infla

2014

Other Studies

75 other studies available for hydrogen and Inflammation

ArticleYear
Boswellia carterii liquisolid systems with promoted anti-inflammatory activity.
    Current drug delivery, 2015, Volume: 12, Issue:4

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Boswellia; Carrageenan; Cellulose; Chemistr

2015
Microcrystalline cellulose induces time-dependent lung functional and inflammatory changes.
    Respiratory physiology & neurobiology, 2008, Dec-31, Volume: 164, Issue:3

    Topics: Airway Resistance; Animals; Bronchoalveolar Lavage Fluid; Cellulose; Excipients; Inflammation; Linea

2008
High concentration of hydrogen ameliorates lipopolysaccharide-induced acute lung injury in a sirt1-dependent manner.
    Respiratory physiology & neurobiology, 2022, Volume: 296

    Topics: Acute Lung Injury; Administration, Inhalation; Animals; Disease Models, Animal; Endothelial Cells; H

2022
Hydrogen-rich water partially alleviate inflammation, oxidative stress and intestinal flora dysbiosis in DSS-induced chronic ulcerative colitis mice.
    Advances in medical sciences, 2022, Volume: 67, Issue:1

    Topics: Animals; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Dysbiosis; Gastrointestinal M

2022
Hydrogen Attenuated Inflammation Response and Oxidative in Hypoxic Ischemic Encephalopathy via Nrf2 Mediated the Inhibition of NLRP3 and NF-κB.
    Neuroscience, 2022, 03-01, Volume: 485

    Topics: Animals; Hydrogen; Hypoxia-Ischemia, Brain; Inflammation; Mice; NF-E2-Related Factor 2; NF-kappa B;

2022
Molecular hydrogen is a promising therapeutic agent for pulmonary disease.
    Journal of Zhejiang University. Science. B, 2022, Feb-15, Volume: 23, Issue:2

    Topics: Acute Lung Injury; Aging; Animals; Anti-Inflammatory Agents; Antioxidants; Asthma; Autophagy; COVID-

2022
Hydrogen-oxygen therapy alleviates clinical symptoms in twelve patients hospitalized with COVID-19: A retrospective study of medical records.
    Medicine, 2022, Mar-04, Volume: 101, Issue:9

    Topics: Adult; China; COVID-19; Female; Humans; Hydrogen; Inflammation; Male; Medical Records; Middle Aged;

2022
Nano-bubble hydrogen water: An effective therapeutic agent against inflammation related disease caused by viral infection in zebrafish model.
    Virologica Sinica, 2022, Volume: 37, Issue:2

    Topics: Animals; Carps; Fish Diseases; Hydrogen; Inflammation; Rhabdoviridae; Rhabdoviridae Infections; Wate

2022
Hydrogen-rich and hyperoxygenate saline inhibits lipopolysaccharide-induced lung injury through mediating NF-κB/NLRP3 signaling pathway in C57BL/6 mice.
    Environmental toxicology, 2022, Volume: 37, Issue:7

    Topics: Acute Lung Injury; Animals; Hydrogen; Hypoxia; Inflammation; Lipopolysaccharides; Lung; Mice; Mice,

2022
Hydrogen-generating Si-based agent protects against skin flap ischemia-reperfusion injury in rats.
    Scientific reports, 2022, 04-13, Volume: 12, Issue:1

    Topics: Animals; Disease Models, Animal; Hydrogen; Inflammation; Rats; Rats, Sprague-Dawley; Reperfusion Inj

2022
Molecular Hydrogen Mediates Neurorestorative Effects After Stroke in Diabetic Rats: the TLR4/NF-κB Inflammatory Pathway.
    Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2023, Volume: 18, Issue:1-2

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hydrogen; Infarction, Middle Cerebral Arter

2023
Narrative on Hydrogen Therapy and its Clinical Applications: Safety and Efficacy.
    Current pharmaceutical design, 2022, Volume: 28, Issue:31

    Topics: Apoptosis; Humans; Hydrogen; Inflammation; Neurodegenerative Diseases; Oxidative Stress

2022
Prophylactic Instillation of Hydrogen-Rich Water Decreases Corneal Inflammation and Promotes Wound Healing by Activating Antioxidant Activity in a Rat Alkali Burn Model.
    International journal of molecular sciences, 2022, Aug-29, Volume: 23, Issue:17

    Topics: Alkalies; Animals; Antioxidants; Burns, Chemical; Corneal Injuries; Disease Models, Animal; Eye Burn

2022
Living Macrophage-Delivered Tetrapod PdH Nanoenzyme for Targeted Atherosclerosis Management by ROS Scavenging, Hydrogen Anti-inflammation, and Autophagy Activation.
    ACS nano, 2022, 10-25, Volume: 16, Issue:10

    Topics: Anti-Inflammatory Agents; Atherosclerosis; Autophagy; Humans; Hydrogen; Inflammation; Macrophages; R

2022
Electrolyzed Hydrogen Water Alleviates Abdominal Pain through Suppression of Colonic Tissue Inflammation in a Rat Model of Inflammatory Bowel Disease.
    Nutrients, 2022, Oct-22, Volume: 14, Issue:21

    Topics: Abdominal Pain; Animals; Colitis; Colon; Hydrogen; Inflammation; Inflammatory Bowel Diseases; Rats;

2022
Inflation using hydrogen improves donor lung quality by regulating mitochondrial function during cold ischemia phase.
    BMC pulmonary medicine, 2023, Jun-17, Volume: 23, Issue:1

    Topics: Apoptosis; Cold Ischemia; Heme Oxygenase-1; Humans; Hydrogen; Inflammation; Lung; NF-E2-Related Fact

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Journal of maxillofacial and oral surgery, 2023, Apr-09

    Topics: Acrylamides; Actins; Adult; African People; Air Pollutants; Alanine Transaminase; Androgens; Animals

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Journal of maxillofacial and oral surgery, 2023, Apr-09

    Topics: Acrylamides; Actins; Adult; African People; Air Pollutants; Alanine Transaminase; Androgens; Animals

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Journal of maxillofacial and oral surgery, 2023, Apr-09

    Topics: Acrylamides; Actins; Adult; African People; Air Pollutants; Alanine Transaminase; Androgens; Animals

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Journal of maxillofacial and oral surgery, 2023, Apr-09

    Topics: Acrylamides; Actins; Adult; African People; Air Pollutants; Alanine Transaminase; Androgens; Animals

2023
Attenuation of pulmonary damage in aged lipopolysaccharide-induced inflammation mice through continuous 2 % hydrogen gas inhalation: A potential therapeutic strategy for geriatric inflammation and survival.
    Experimental gerontology, 2023, Volume: 180

    Topics: Aged; Animals; Biomarkers; Humans; Hydrogen; Inflammation; Lipopolysaccharides; Lung; Male; Mice

2023
Hydrogen gas improves photothermal therapy of tumor and restrains the relapse of distant dormant tumor.
    Biomaterials, 2019, Volume: 223

    Topics: Ammonia; Animals; Biocompatible Materials; Boranes; Breast Neoplasms; Chlorocebus aethiops; COS Cell

2019
Comparative study on protective effect of hydrogen rich saline and adipose-derived stem cells on hepatic ischemia-reperfusion and hepatectomy injury in swine.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 120

    Topics: Adipocytes; Animals; Apoptosis; Hepatectomy; Hydrogen; Inflammation; Liver; Liver Function Tests; Li

2019
Hydrogen-rich Saline Alleviated the Hyperpathia and Microglia Activation via Autophagy Mediated Inflammasome Inactivation in Neuropathic Pain Rats.
    Neuroscience, 2019, 11-21, Volume: 421

    Topics: Animals; Autophagy; Behavior Rating Scale; Calcium-Binding Proteins; CARD Signaling Adaptor Proteins

2019
Hydrogen ameliorates lung injury in a rat model of subacute exposure to concentrated ambient PM2.5 via Aryl hydrocarbon receptor.
    International immunopharmacology, 2019, Volume: 77

    Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Cytokines; Disease Models, Animal; Hydrogen;

2019
Immune response of macrophages on super-hydrophilic TiO
    Journal of biomaterials applications, 2020, Volume: 34, Issue:9

    Topics: Animals; Biocompatible Materials; Cell Adhesion; Cell Proliferation; Cell Survival; Chemokines; Cyto

2020
Chronic molecular hydrogen inhalation mitigates short and long-term memory loss in polymicrobial sepsis.
    Brain research, 2020, 07-15, Volume: 1739

    Topics: Administration, Inhalation; Animals; Antioxidants; Apoptosis; Brain; Disease Models, Animal; Hippoca

2020
Hydrogen attenuates radiation-induced intestinal damage by reducing oxidative stress and inflammatory response.
    International immunopharmacology, 2020, Volume: 84

    Topics: Animals; Apoptosis; Cell Line; Cell Survival; Gamma Rays; Hydrogen; Inflammation; Intestines; Male;

2020
Hydrogen gas (XEN) inhalation ameliorates airway inflammation in asthma and COPD patients.
    QJM : monthly journal of the Association of Physicians, 2020, Dec-01, Volume: 113, Issue:12

    Topics: Administration, Inhalation; Adult; Aged; Asthma; Breath Tests; Cytokines; Female; Gases; Humans; Hyd

2020
Hydrogen inhalation inhibits microglia activation and neuroinflammation in a rat model of traumatic brain injury.
    Brain research, 2020, 12-01, Volume: 1748

    Topics: Animals; Brain; Brain Injuries, Traumatic; Disease Models, Animal; Hydrogen; Inflammation; Male; Mic

2020
Hydrogen Gas as an Exotic Performance-Enhancing Agent: Challenges and Opportunities.
    Current pharmaceutical design, 2021, Volume: 27, Issue:5

    Topics: Animals; Exercise; Humans; Hydrogen; Inflammation; Oxidative Stress

2021
Hydrogen therapy as an effective and novel adjuvant treatment against COVID-19.
    QJM : monthly journal of the Association of Physicians, 2021, 02-18, Volume: 114, Issue:1

    Topics: Asthma; COVID-19; Humans; Hydrogen; Inflammation; Pulmonary Disease, Chronic Obstructive; SARS-CoV-2

2021
Alleviation of the chronic stress response attributed to the antioxidant and anti-inflammatory effects of electrolyzed hydrogen water.
    Biochemical and biophysical research communications, 2021, 01-08, Volume: 535

    Topics: Adrenocorticotropic Hormone; Animals; Anti-Inflammatory Agents; Antioxidants; Electrodes; Electrolys

2021
The protective effect of hydrogen-rich water on rats with type 2 diabetes mellitus.
    Molecular and cellular biochemistry, 2021, Volume: 476, Issue:8

    Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; H

2021
Effects of hydrogen as adjuvant treatment for unstable angina.
    Experimental biology and medicine (Maywood, N.J.), 2021, Volume: 246, Issue:18

    Topics: Angina, Unstable; Anti-Inflammatory Agents; Antioxidants; Atherosclerosis; Cells, Cultured; Human Um

2021
Hydrogen alleviates cell damage and acute lung injury in sepsis via PINK1/Parkin-mediated mitophagy.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2021, Volume: 70, Issue:8

    Topics: Acute Lung Injury; Animals; Autophagy; Cell Line; Hydrogen; Inflammation; Lipopolysaccharides; Lung;

2021
A PdMo bimetallene with precise wavelength adjustment and catalysis for synergistic photothermal ablation and hydrogen therapy of cancer at different depths.
    Journal of materials chemistry. B, 2021, 08-28, Volume: 9, Issue:32

    Topics: Animals; Catalysis; Cell Line; Cytokines; Gene Expression Regulation; Humans; Hydrogen; Inflammation

2021
Molecular hydrogen inhalation attenuates postoperative cognitive impairment in rats.
    Neuroreport, 2017, Aug-02, Volume: 28, Issue:11

    Topics: Animals; Cognition; Cognitive Dysfunction; Cytokines; Hippocampus; Hydrogen; Inflammation; Male; Maz

2017
In Situ Nanoreactor for Photosynthesizing H
    Journal of the American Chemical Society, 2017, 09-20, Volume: 139, Issue:37

    Topics: Animals; Gold; Hydrogen; Inflammation; Lipopolysaccharides; Metal Nanoparticles; Mice; Molecular Con

2017
[Effects of hydrogen on the lung damage of mice at early stage of severe burn].
    Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns, 2017, Nov-20, Volume: 33, Issue:11

    Topics: Acute Lung Injury; Animals; Body Surface Area; Burns; Enzyme-Linked Immunosorbent Assay; HMGB1 Prote

2017
The Anti-inflammatory Effect of Hydrogen on Lung Transplantation Model of Pulmonary Microvascular Endothelial Cells During Cold Storage Period.
    Transplantation, 2018, Volume: 102, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cold Temperature; Endothelial Cells; Hydrogen; Hydroge

2018
[Role of Rho/ROCK signaling pathway in the protective effects of hydrogen against acute lung injury in septic mice].
    Zhonghua wei zhong bing ji jiu yi xue, 2016, Volume: 28, Issue:5

    Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Hydrogen; Inflamma

2016
Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model.
    Brain research bulletin, 2018, Volume: 142

    Topics: Administration, Inhalation; Animals; Apoptosis; Brain; Cerebral Hemorrhage; Disease Models, Animal;

2018
Evaluation of the effects of chlorpyrifos combined with lipopolysaccharide stress on neuroinflammation and spatial memory in neonatal rats.
    Toxicology, 2018, 12-01, Volume: 410

    Topics: Animals; Animals, Newborn; Astrocytes; Chlorpyrifos; Female; Gene Expression; HMGB1 Protein; Hydroge

2018
Hydrogen-Rich Saline Ameliorates Experimental Autoimmune Encephalomyelitis in C57BL/6 Mice Via the Nrf2-ARE Signaling Pathway.
    Inflammation, 2019, Volume: 42, Issue:2

    Topics: Animals; Demyelinating Diseases; Encephalomyelitis, Autoimmune, Experimental; Hydrogen; Inflammation

2019
Hydrogen-rich solution attenuates cold ischemia-reperfusion injury in rat liver transplantation.
    BMC gastroenterology, 2019, Feb-08, Volume: 19, Issue:1

    Topics: Adenosine; Allopurinol; Animals; Apoptosis; Cold Temperature; Glutathione; Hepatocytes; Hydrogen; Hy

2019
Hydrogen Alleviates Necroptosis and Cognitive Deficits in Lithium-Pilocarpine Model of Status Epilepticus.
    Cellular and molecular neurobiology, 2019, Volume: 39, Issue:6

    Topics: Animals; Apoptosis; CA1 Region, Hippocampal; Cognition Disorders; Disease Models, Animal; Hydrogen;

2019
Hydrogen inhalation protects hypoxic-ischemic brain damage by attenuating inflammation and apoptosis in neonatal rats.
    Experimental biology and medicine (Maywood, N.J.), 2019, Volume: 244, Issue:12

    Topics: Administration, Inhalation; Animals; Apoptosis; Brain Injuries; Female; Gene Expression Regulation;

2019
Hydrogen Gas from Inflammation Treatment to Cancer Therapy.
    ACS nano, 2019, 08-27, Volume: 13, Issue:8

    Topics: Drug Delivery Systems; Humans; Hydrogen; Inflammation; Nanostructures; Neoplasms

2019
Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo.
    American journal of physiology. Lung cellular and molecular physiology, 2013, May-15, Volume: 304, Issue:10

    Topics: Animals; Apoptosis; Cytokines; Epithelial Cells; Gases; Heme Oxygenase-1; Hydrogen; Hyperoxia; Infla

2013
Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo.
    American journal of physiology. Lung cellular and molecular physiology, 2013, May-15, Volume: 304, Issue:10

    Topics: Animals; Apoptosis; Cytokines; Epithelial Cells; Gases; Heme Oxygenase-1; Hydrogen; Hyperoxia; Infla

2013
Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo.
    American journal of physiology. Lung cellular and molecular physiology, 2013, May-15, Volume: 304, Issue:10

    Topics: Animals; Apoptosis; Cytokines; Epithelial Cells; Gases; Heme Oxygenase-1; Hydrogen; Hyperoxia; Infla

2013
Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo.
    American journal of physiology. Lung cellular and molecular physiology, 2013, May-15, Volume: 304, Issue:10

    Topics: Animals; Apoptosis; Cytokines; Epithelial Cells; Gases; Heme Oxygenase-1; Hydrogen; Hyperoxia; Infla

2013
Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo.
    American journal of physiology. Lung cellular and molecular physiology, 2013, May-15, Volume: 304, Issue:10

    Topics: Animals; Apoptosis; Cytokines; Epithelial Cells; Gases; Heme Oxygenase-1; Hydrogen; Hyperoxia; Infla

2013
Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo.
    American journal of physiology. Lung cellular and molecular physiology, 2013, May-15, Volume: 304, Issue:10

    Topics: Animals; Apoptosis; Cytokines; Epithelial Cells; Gases; Heme Oxygenase-1; Hydrogen; Hyperoxia; Infla

2013
Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo.
    American journal of physiology. Lung cellular and molecular physiology, 2013, May-15, Volume: 304, Issue:10

    Topics: Animals; Apoptosis; Cytokines; Epithelial Cells; Gases; Heme Oxygenase-1; Hydrogen; Hyperoxia; Infla

2013
Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo.
    American journal of physiology. Lung cellular and molecular physiology, 2013, May-15, Volume: 304, Issue:10

    Topics: Animals; Apoptosis; Cytokines; Epithelial Cells; Gases; Heme Oxygenase-1; Hydrogen; Hyperoxia; Infla

2013
Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo.
    American journal of physiology. Lung cellular and molecular physiology, 2013, May-15, Volume: 304, Issue:10

    Topics: Animals; Apoptosis; Cytokines; Epithelial Cells; Gases; Heme Oxygenase-1; Hydrogen; Hyperoxia; Infla

2013
Non-invasive panel tests for gastrointestinal motility monitoring within the MARS-500 Project.
    World journal of gastroenterology, 2013, Volume: 19, Issue:14

    Topics: Acetates; Adult; Astronauts; Breath Tests; Caprylates; Carbon Dioxide; Carbon Isotopes; Feces; Gastr

2013
Protective role of hydrogen-rich water on aspirin-induced gastric mucosal damage in rats.
    World journal of gastroenterology, 2014, Feb-14, Volume: 20, Issue:6

    Topics: Animals; Aspirin; Cyclooxygenase 2; Gastric Mucosa; Hydrogen; Inflammation; Interleukin-1beta; Inter

2014
Hydrogen in lung reconditioning--more than just inflation.
    Transplantation, 2014, Sep-15, Volume: 98, Issue:5

    Topics: Animals; Hydrogen; Inflammation; Lung; Lung Transplantation; Male; Perfusion; Protective Agents

2014
Hydrogen preconditioning during ex vivo lung perfusion improves the quality of lung grafts in rats.
    Transplantation, 2014, Sep-15, Volume: 98, Issue:5

    Topics: Animals; Biomarkers; Cytokines; Heme Oxygenase-1; Hydrogen; Inflammation; Lactic Acid; Lung; Lung Tr

2014
Luminal injection of hydrogen-rich solution attenuates intestinal ischemia-reperfusion injury in rats.
    Transplantation, 2015, Volume: 99, Issue:3

    Topics: Administration, Inhalation; Administration, Oral; Animals; Antioxidants; Apoptosis; Cytokines; Gluco

2015
Beneficial effects of hydrogen-rich saline on early burn-wound progression in rats.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Animals; Burns; Disease Progression; Hydrogen; Inflammation; Male; Oxidative Stress; Rats; Rats, Spr

2015
Improvement of psoriasis-associated arthritis and skin lesions by treatment with molecular hydrogen: A report of three cases.
    Molecular medicine reports, 2015, Volume: 12, Issue:2

    Topics: Aged; Aged, 80 and over; Arthritis, Psoriatic; Female; Free Radical Scavengers; Humans; Hydrogen; Hy

2015
Effects of hydrogen-rich saline on early acute kidney injury in severely burned rats by suppressing oxidative stress induced apoptosis and inflammation.
    Journal of translational medicine, 2015, Jun-06, Volume: 13

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Apoptosis; Blotting, Western; Burns; Creatinine;

2015
Hydrogen-Rich Saline Attenuated Subarachnoid Hemorrhage-Induced Early Brain Injury in Rats by Suppressing Inflammatory Response: Possible Involvement of NF-κB Pathway and NLRP3 Inflammasome.
    Molecular neurobiology, 2016, Volume: 53, Issue:5

    Topics: Animals; Antioxidants; Apoptosis; Brain; Brain Edema; Brain Injuries; Cerebral Cortex; Cytokines; Do

2016
Hydrogen-Rich Saline Attenuates Lipopolysaccharide-Induced Heart Dysfunction by Restoring Fatty Acid Oxidation in Rats by Mitigating C-Jun N-Terminal Kinase Activation.
    Shock (Augusta, Ga.), 2015, Volume: 44, Issue:6

    Topics: Adenosine Triphosphate; Animals; Echocardiography; Fatty Acids; Heart; Heart Diseases; Heart Ventric

2015
Hydrogen-Rich Saline Attenuates Acute Hepatic Injury in Acute Necrotizing Pancreatitis by Inhibiting Inflammation and Apoptosis, Involving JNK and p38 Mitogen-Activated Protein Kinase-dependent Reactive Oxygen Species.
    Pancreas, 2016, Volume: 45, Issue:10

    Topics: Animals; Apoptosis; Hydrogen; Inflammation; p38 Mitogen-Activated Protein Kinases; Pancreatitis, Acu

2016
Hydrogen-Rich Saline Attenuates Cardiac and Hepatic Injury in Doxorubicin Rat Model by Inhibiting Inflammation and Apoptosis.
    Mediators of inflammation, 2016, Volume: 2016

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Aspartate Aminotransferases; Chemical an

2016
Hydrogen inhalation ameliorates oxidative stress in transplantation induced intestinal graft injury.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2008, Volume: 8, Issue:10

    Topics: Administration, Inhalation; Animals; Antioxidants; Gases; Hydrogen; Inflammation; Intestines; Male;

2008
Intestinal bacterial overgrowth in CAPD patients with hypokalaemia.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2009, Volume: 24, Issue:4

    Topics: Adult; Bacterial Infections; Breath Tests; Diabetes Complications; Female; Humans; Hydrogen; Hypokal

2009
Neuroprotective effects of hydrogen saline in neonatal hypoxia-ischemia rat model.
    Brain research, 2009, Feb-23, Volume: 1256

    Topics: Animals; Animals, Newborn; Body Weight; Brain; Calcium-Binding Proteins; Caspase 3; Cell Death; Dise

2009
Hydrogen-rich saline protects against intestinal ischemia/reperfusion injury in rats.
    Free radical research, 2009, Volume: 43, Issue:5

    Topics: Animals; Cytokines; Hydrogen; Inflammation; Inflammation Mediators; Infusions, Intravenous; Intestin

2009
Factors related to colonic fermentation of nondigestible carbohydrates of a previous evening meal increase tissue glucose uptake and moderate glucose-associated inflammation.
    The American journal of clinical nutrition, 2010, Volume: 91, Issue:1

    Topics: Blood Glucose; Bread; Breath Tests; Carbon Isotopes; Colon; Cross-Over Studies; Dietary Carbohydrate

2010
Oral hydrogen water prevents chronic allograft nephropathy in rats.
    Kidney international, 2010, Volume: 77, Issue:2

    Topics: Administration, Oral; Animals; Antioxidants; Biomarkers; Graft Survival; Hydrogen; Inflammation; Kid

2010
Hydrogen gas improves survival rate and organ damage in zymosan-induced generalized inflammation model.
    Shock (Augusta, Ga.), 2010, Volume: 34, Issue:5

    Topics: Administration, Inhalation; Animals; Antioxidants; Biomarkers; Cytokines; Dinoprost; Drug Evaluation

2010
Beneficial effects of hydrogen gas against spinal cord ischemia-reperfusion injury in rabbits.
    Brain research, 2011, Mar-10, Volume: 1378

    Topics: Animals; Antioxidants; Apoptosis; Cytokines; Hydrogen; In Situ Nick-End Labeling; Inflammation; Male

2011
Hydrogen-rich saline reduces delayed neurologic sequelae in experimental carbon monoxide toxicity.
    Critical care medicine, 2011, Volume: 39, Issue:4

    Topics: Animals; Brain; Brain Chemistry; Calcium-Binding Proteins; Carbon Monoxide Poisoning; Cerebral Corte

2011
Hydrogen-rich saline reduces oxidative stress and inflammation by inhibit of JNK and NF-κB activation in a rat model of amyloid-beta-induced Alzheimer's disease.
    Neuroscience letters, 2011, Mar-17, Volume: 491, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Disease Models, Animal; Enzyme Activation;

2011
Hydrogen-rich saline is cerebroprotective in a rat model of deep hypothermic circulatory arrest.
    Neurochemical research, 2011, Volume: 36, Issue:8

    Topics: Animals; Apoptosis; Brain Injuries; Caspase 3; Circulatory Arrest, Deep Hypothermia Induced; Hydroge

2011
Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and apoptosis.
    Shock (Augusta, Ga.), 2012, Volume: 37, Issue:5

    Topics: Acute Lung Injury; Animals; Apoptosis; Cytokines; Hydrogen; Inflammation; Lipopolysaccharides; Lung;

2012
Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and apoptosis.
    Shock (Augusta, Ga.), 2012, Volume: 37, Issue:5

    Topics: Acute Lung Injury; Animals; Apoptosis; Cytokines; Hydrogen; Inflammation; Lipopolysaccharides; Lung;

2012
Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and apoptosis.
    Shock (Augusta, Ga.), 2012, Volume: 37, Issue:5

    Topics: Acute Lung Injury; Animals; Apoptosis; Cytokines; Hydrogen; Inflammation; Lipopolysaccharides; Lung;

2012
Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and apoptosis.
    Shock (Augusta, Ga.), 2012, Volume: 37, Issue:5

    Topics: Acute Lung Injury; Animals; Apoptosis; Cytokines; Hydrogen; Inflammation; Lipopolysaccharides; Lung;

2012
Molecular hydrogen reduces LPS-induced neuroinflammation and promotes recovery from sickness behaviour in mice.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Animals; Behavior, Animal; Central Nervous System Diseases; Culture Media; Cytokines; Hydrogen; Infl

2012
Hydrogen-supplemented drinking water protects cardiac allografts from inflammation-associated deterioration.
    Transplant international : official journal of the European Society for Organ Transplantation, 2012, Volume: 25, Issue:12

    Topics: Adenosine Triphosphate; Animals; Drinking; Graft Rejection; Heart Transplantation; Hydrogen; Inflamm

2012
Oxidative cross-linking of tryptophan to glycine restrains matrix metalloproteinase activity: specific structural motifs control protein oxidation.
    The Journal of biological chemistry, 2004, Feb-20, Volume: 279, Issue:8

    Topics: Amino Acid Motifs; Catalytic Domain; Chromatography, High Pressure Liquid; Cross-Linking Reagents; D

2004
Recently published papers: more about EGDT, experimental therapies and some inconvenient truths.
    Critical care (London, England), 2007, Volume: 11, Issue:5

    Topics: Animals; Critical Care; Cytochromes c; Disease Models, Animal; Education, Medical; Humans; Hydrogen;

2007