Page last updated: 2024-10-18

hydrogen and Hyperplasia

hydrogen has been researched along with Hyperplasia in 5 studies

Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.

Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.

Research Excerpts

ExcerptRelevanceReference
"Hydrogen-rich saline has been reported to prevent neointimal hyperplasia induced by carotid balloon injury."7.79Hydrogen-rich saline attenuates vascular smooth muscle cell proliferation and neointimal hyperplasia by inhibiting reactive oxygen species production and inactivating the Ras-ERK1/2-MEK1/2 and Akt pathways. ( Chen, X; Chen, Y; Jiang, J; Li, Y; Miao, H; Sun, X, 2013)
"Drinking HW significantly reduced neointima formation after vein grafting in rats."5.38Oral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats. ( Bermudez, CA; Billiar, TR; Kawamura, T; Masutani, K; Nakao, A; Peng, X; Pribis, JP; Stolz, DB; Sun, Q; Sun, X; Toyoda, Y, 2012)
"Hydrogen-rich saline pretreatment attenuated CS-induced mucus accumulation in the bronchiolar lumen, goblet cell hyperplasia, muc5ac over-expression and abnormal cell apoptosis in the airway epithelium as well as malondialdehyde increase in the BALF."3.79Attenuation of cigarette smoke-induced airway mucus production by hydrogen-rich saline in rats. ( Dong, Y; Huang, H; Li, Q; Ning, Y; Shang, Y; Xu, W; Zhang, J, 2013)
"Hydrogen-rich saline has been reported to prevent neointimal hyperplasia induced by carotid balloon injury."3.79Hydrogen-rich saline attenuates vascular smooth muscle cell proliferation and neointimal hyperplasia by inhibiting reactive oxygen species production and inactivating the Ras-ERK1/2-MEK1/2 and Akt pathways. ( Chen, X; Chen, Y; Jiang, J; Li, Y; Miao, H; Sun, X, 2013)
"Drinking HW significantly reduced neointima formation after vein grafting in rats."1.38Oral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats. ( Bermudez, CA; Billiar, TR; Kawamura, T; Masutani, K; Nakao, A; Peng, X; Pribis, JP; Stolz, DB; Sun, Q; Sun, X; Toyoda, Y, 2012)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ning, Y1
Shang, Y1
Huang, H1
Zhang, J1
Dong, Y1
Xu, W1
Li, Q1
Joddar, B1
Shaffer, RJ1
Reen, RK1
Gooch, KJ1
Sun, Q2
Kawamura, T1
Masutani, K1
Peng, X1
Stolz, DB1
Pribis, JP1
Billiar, TR1
Sun, X2
Bermudez, CA1
Toyoda, Y1
Nakao, A1
Chen, Y1
Jiang, J1
Miao, H1
Chen, X1
Li, Y1
Mackinnon, WB1
Delbridge, L1
Russell, P1
Lean, CL1
May, GL1
Doran, S1
Dowd, S1
Mountford, CE1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy and Safety of Hydrogen Inhalation on Bronchiectasis (HYBRID): A Randomized, Multi-center, Double-blind, Parallel-group Study[NCT02765295]120 participants (Anticipated)Interventional2016-06-01Recruiting
Adjuvant Therapy for Severe COPD Patients in the Stable Phase by an Oxyhydrogen Generator With Nebulizer: A Multi-centric, Randomized, Parallel-control and Double-blinded Clinic Study[NCT02850185]170 participants (Anticipated)Interventional2016-07-15Recruiting
Adjuvant Therapy for Severe Asthma by an Oxyhydrogen Generator With Nebulizer: A Multi-centric, Randomized, Parallel-control and Double-blinded Clinic Study on Effectiveness and Safety[NCT02883582]150 participants (Anticipated)Interventional2016-08-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

5 other studies available for hydrogen and Hyperplasia

ArticleYear
Attenuation of cigarette smoke-induced airway mucus production by hydrogen-rich saline in rats.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Epithelial Cells; ErbB Receptors; Goblet Cells; Hy

2013
Attenuation of cigarette smoke-induced airway mucus production by hydrogen-rich saline in rats.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Epithelial Cells; ErbB Receptors; Goblet Cells; Hy

2013
Attenuation of cigarette smoke-induced airway mucus production by hydrogen-rich saline in rats.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Epithelial Cells; ErbB Receptors; Goblet Cells; Hy

2013
Attenuation of cigarette smoke-induced airway mucus production by hydrogen-rich saline in rats.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Epithelial Cells; ErbB Receptors; Goblet Cells; Hy

2013
Attenuation of cigarette smoke-induced airway mucus production by hydrogen-rich saline in rats.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Epithelial Cells; ErbB Receptors; Goblet Cells; Hy

2013
Attenuation of cigarette smoke-induced airway mucus production by hydrogen-rich saline in rats.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Epithelial Cells; ErbB Receptors; Goblet Cells; Hy

2013
Attenuation of cigarette smoke-induced airway mucus production by hydrogen-rich saline in rats.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Epithelial Cells; ErbB Receptors; Goblet Cells; Hy

2013
Attenuation of cigarette smoke-induced airway mucus production by hydrogen-rich saline in rats.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Epithelial Cells; ErbB Receptors; Goblet Cells; Hy

2013
Attenuation of cigarette smoke-induced airway mucus production by hydrogen-rich saline in rats.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Epithelial Cells; ErbB Receptors; Goblet Cells; Hy

2013
Arterial pO₂ stimulates intimal hyperplasia and serum stimulates inward eutrophic remodeling in porcine saphenous veins cultured ex vivo.
    Biomechanics and modeling in mechanobiology, 2011, Volume: 10, Issue:2

    Topics: Aldehydes; Animals; Arteries; Biomass; Biomechanical Phenomena; Carbon Dioxide; Cell Death; Cell Pro

2011
Oral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats.
    Cardiovascular research, 2012, Apr-01, Volume: 94, Issue:1

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Antioxidants; Aorta, Abdominal; Cardiovascu

2012
Hydrogen-rich saline attenuates vascular smooth muscle cell proliferation and neointimal hyperplasia by inhibiting reactive oxygen species production and inactivating the Ras-ERK1/2-MEK1/2 and Akt pathways.
    International journal of molecular medicine, 2013, Volume: 31, Issue:3

    Topics: Angioplasty, Balloon, Coronary; Animals; Apoptosis; Cell Cycle Checkpoints; Cell Movement; Cell Prol

2013
Two-dimensional proton magnetic resonance spectroscopy for tissue characterization of thyroid neoplasms.
    World journal of surgery, 1996, Volume: 20, Issue:7

    Topics: Adenoma; Amino Acids; Carcinoma; Cholesterol; Cholesterol Esters; Diglycerides; Fucose; Humans; Hydr

1996