Page last updated: 2024-10-18

hydrogen and Heart Disease, Ischemic

hydrogen has been researched along with Heart Disease, Ischemic in 25 studies

Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.

Research Excerpts

ExcerptRelevanceReference
"To explore the effects of hydrogen-rich saline on Akt/GSK3β signaling pathways and cardiac function during myocardial ischemia-reperfusion (I/R) in rats."7.81[Effects of hydrogen-rich saline on Akt/GSK3β signaling pathways and cardiac function during myocardial ischemia-reperfusion in rats]. ( Li, H; Li, J; Wang, B; Yue, L; Zhao, Y, 2015)
"To study the possible anti-inflammatory effect of hydrogen-rich saline (H(2) saline) on rat hearts with regional myocardial ischemia and reperfusion (I/R)."7.77Anti-inflammatory effect of hydrogen-rich saline in a rat model of regional myocardial ischemia and reperfusion. ( He, B; Sun, Q; Sun, X; Wang, Z; Xiao, J; Zhang, Y, 2011)
"To explore the effects of hydrogen-rich saline on Akt/GSK3β signaling pathways and cardiac function during myocardial ischemia-reperfusion (I/R) in rats."3.81[Effects of hydrogen-rich saline on Akt/GSK3β signaling pathways and cardiac function during myocardial ischemia-reperfusion in rats]. ( Li, H; Li, J; Wang, B; Yue, L; Zhao, Y, 2015)
"To study the possible anti-inflammatory effect of hydrogen-rich saline (H(2) saline) on rat hearts with regional myocardial ischemia and reperfusion (I/R)."3.77Anti-inflammatory effect of hydrogen-rich saline in a rat model of regional myocardial ischemia and reperfusion. ( He, B; Sun, Q; Sun, X; Wang, Z; Xiao, J; Zhang, Y, 2011)
"The inhibition of Na(+)-H+ exchange (NHE) with amiloride analogues in vitro has been shown to prevent reperfusion arrhythmias and additional cell necrosis."3.69Role of Na(+)-H+ exchange on reperfusion related myocardial injury and arrhythmias in an open-chest swine model. ( Fukuta, M; Iwa, T; Kobayashi, T; Uesugi, M; Wakida, Y, 1996)
"Myocardial ischemia is associated with an intracellular acidosis recovering after reperfusion."1.29[Stimulation of the alpha-1 adrenergic receptors during simulated reperfusion after myocardial acidosis. The evidence for an arrhythmogenic role of the Na+/H+ exchanger]. ( Gambassi, G, 1993)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's20 (80.00)18.2507
2000's1 (4.00)29.6817
2010's2 (8.00)24.3611
2020's2 (8.00)2.80

Authors

AuthorsStudies
Kiyoi, T1
Liu, S1
Takemasa, E1
Nakaoka, H1
Hato, N1
Mogi, M1
Nie, C1
Ding, X1
A, R1
Zheng, M1
Li, Z1
Pan, S1
Yang, W1
Yue, L1
Li, H1
Zhao, Y1
Li, J1
Wang, B1
Zhang, Y1
Sun, Q1
He, B1
Xiao, J1
Wang, Z1
Sun, X1
Mitani, A1
Yasui, H1
Tokunaga, K1
Navon, G1
Werrmann, JG1
Maron, R1
Cohen, SM1
Yamamoto, M1
Lee, JD1
Shimizu, H1
Kawasaki, N1
Hara, A1
Ishii, Y1
Nakamura, T1
De Bruyne, B1
Bronzwaer, JG1
Heyndrickx, GR1
Paulus, WJ1
Schussheim, AE1
Radda, GK2
Karmazyn, M1
Gambassi, G1
Xu, L1
Mann, G1
Meissner, G1
Fluck, DS2
Etherington, PJ2
O'Hare, D1
Winlove, CP2
Sheridan, DJ2
Fukuta, M1
Wakida, Y1
Iwa, T1
Uesugi, M1
Kobayashi, T1
Fliegel, L1
Wang, H1
Liu, H1
Cala, PM1
Anderson, SE1
Dyck, JR1
Lopaschuk, GD1
Bak, MI1
Ingwall, JS1
Stamper, JJ1
Pohost, GM1
Befroy, DE1
Powell, T1
Clarke, K1
Toda, H1
Noguchi, T1
Miyagishi, A1
Ito, N1
Umekawa, K1
Sato, Y1
Kitano, M1
Ohashi, N1
Bottomley, PA1
Lee, RF1
Constantinides, CD1
Ouwerkerk, R1
Weiss, RG1
Scholz, W1
Albus, U1
Linz, W1
Martorana, P1
Lang, HJ1
Schölkens, BA1
Matsuda, N1
Kuroda, H1
Ashida, Y1
Okada, M1
Mori, T1

Reviews

2 reviews available for hydrogen and Heart Disease, Ischemic

ArticleYear
Regulation of the Na+/H+ exchanger in the mammalian myocardium.
    Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:8

    Topics: Adrenergic alpha-Agonists; Animals; Catecholamines; Cell Differentiation; Gene Expression Regulation

1997
Assessing myocardial ischemic insult using nuclear magnetic resonance spectroscopy.
    American journal of cardiac imaging, 1992, Volume: 6, Issue:3

    Topics: Animals; Calcium; Fluorine; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Myocardial Ischemia;

1992

Other Studies

23 other studies available for hydrogen and Heart Disease, Ischemic

ArticleYear
Constitutive hydrogen inhalation prevents vascular remodeling via reduction of oxidative stress.
    PloS one, 2020, Volume: 15, Issue:4

    Topics: Administration, Inhalation; Animals; Disease Models, Animal; DNA Damage; Down-Regulation; Gases; Hum

2020
Hydrogen gas inhalation alleviates myocardial ischemia-reperfusion injury by the inhibition of oxidative stress and NLRP3-mediated pyroptosis in rats.
    Life sciences, 2021, May-01, Volume: 272

    Topics: Administration, Inhalation; Animals; Cell Survival; Hydrogen; Inflammasomes; Male; Myocardial Infarc

2021
[Effects of hydrogen-rich saline on Akt/GSK3β signaling pathways and cardiac function during myocardial ischemia-reperfusion in rats].
    Zhonghua yi xue za zhi, 2015, May-19, Volume: 95, Issue:19

    Topics: Animals; Cardiovascular Physiological Phenomena; Coronary Artery Disease; Glycogen Synthase Kinase 3

2015
Anti-inflammatory effect of hydrogen-rich saline in a rat model of regional myocardial ischemia and reperfusion.
    International journal of cardiology, 2011, Apr-01, Volume: 148, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiotonic Agents; Disease Models, Animal; Hydrog

2011
Effect of ischemic preconditioning on ischemia-induced contractile failure and accumulation of extracellular H+ and K+.
    Japanese circulation journal, 1994, Volume: 58, Issue:12

    Topics: Adaptation, Physiological; Animals; Energy Metabolism; Hydrogen; Male; Myocardial Contraction; Myoca

1994
31P NMR and triple quantum filtered 23Na NMR studies of the effects of inhibition of Na+/H+ exchange on intracellular sodium and pH in working and ischemic hearts.
    Magnetic resonance in medicine, 1994, Volume: 32, Issue:5

    Topics: Acidosis; Amiloride; Animals; Biological Transport, Active; Cardiac Output; Coronary Circulation; En

1994
Evaluation of post-ischemic myocardial metabolism by 1H-magnetic resonance spectroscopy in the rabbit heart.
    Japanese circulation journal, 1994, Volume: 58, Issue:9

    Topics: Alanine; Animals; Carnitine; Hydrogen; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Myoca

1994
Comparative effects of ischemia and hypoxemia on left ventricular systolic and diastolic function in humans.
    Circulation, 1993, Volume: 88, Issue:2

    Topics: Adult; Aged; Coronary Circulation; Diastole; Female; Humans; Hydrogen; Hypoxia; Lactates; Lactic Aci

1993
Study of ischemic myocardial buffering capacity in perfused rat heart through rapidly interleaved 1H and 31P MRS measurements.
    Magnetic resonance in medicine, 1993, Volume: 30, Issue:1

    Topics: Animals; Buffers; Hydrogen; Hydrogen-Ion Concentration; Lactates; Magnetic Resonance Spectroscopy; M

1993
Na+/H+ exchange inhibitors reverse lactate-induced depression in postischaemic ventricular recovery.
    British journal of pharmacology, 1993, Volume: 108, Issue:1

    Topics: Amiloride; Animals; Carrier Proteins; Heart; Hydrogen; In Vitro Techniques; Lactates; Lactic Acid; M

1993
[Stimulation of the alpha-1 adrenergic receptors during simulated reperfusion after myocardial acidosis. The evidence for an arrhythmogenic role of the Na+/H+ exchanger].
    Cardiologia (Rome, Italy), 1993, Volume: 38, Issue:1

    Topics: Acidosis; Animals; Arrhythmias, Cardiac; Calcium; Fluorescent Dyes; Heart; Hydrogen; Hydrogen-Ion Co

1993
Regulation of cardiac Ca2+ release channel (ryanodine receptor) by Ca2+, H+, Mg2+, and adenine nucleotides under normal and simulated ischemic conditions.
    Circulation research, 1996, Volume: 79, Issue:6

    Topics: Animals; Calcium; Calcium Channels; Dogs; Hydrogen; Hydrogen-Ion Concentration; Ion Transport; Magne

1996
Myocardial tissue perfusion determined by particulate and diffusible tracers during ischaemia: what is measured?
    Cardiovascular research, 1996, Volume: 32, Issue:5

    Topics: Animals; Biological Transport; Heart; Hydrogen; Male; Microscopy, Fluorescence; Microspheres; Myocar

1996
Role of Na(+)-H+ exchange on reperfusion related myocardial injury and arrhythmias in an open-chest swine model.
    Pacing and clinical electrophysiology : PACE, 1996, Volume: 19, Issue:11 Pt 2

    Topics: Action Potentials; Amiloride; Animals; Arrhythmias, Cardiac; Calcium; Cardiac Pacing, Artificial; Co

1996
Ethylisopropylamiloride diminishes changes in intracellular Na, Ca and pH in ischemic newborn myocardium.
    Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:8

    Topics: Adenosine Triphosphate; Age Factors; Amiloride; Animals; Animals, Newborn; Anti-Arrhythmia Agents; C

1997
Glucose metabolism, H+ production and Na+/H+-exchanger mRNA levels in ischemic hearts from diabetic rats.
    Molecular and cellular biochemistry, 1998, Volume: 180, Issue:1-2

    Topics: Animals; Diabetes Mellitus, Experimental; Glucose; Glycolysis; Hydrogen; Islets of Langerhans Transp

1998
Regulation of cardiac AMP-specific 5'-nucleotidase during ischemia mediates ATP resynthesis on reflow.
    The American journal of physiology, 1998, Volume: 274, Issue:4

    Topics: 5'-Nucleotidase; Adenosine Triphosphate; Animals; Hydrogen; Hydrogen-Ion Concentration; In Vitro Tec

1998
Solute exchange in the rabbit myocardium: ischaemia, reflow, and myocardial necrosis.
    Basic research in cardiology, 1998, Volume: 93, Issue:5

    Topics: Animals; Arterial Occlusive Diseases; Capillary Permeability; Coronary Circulation; Coronary Disease

1998
Osmotic shock: modulation of contractile function, pHi, and ischemic damage in perfused guinea pig heart.
    The American journal of physiology, 1999, Volume: 276, Issue:4

    Topics: Animals; Bicarbonates; Buffers; Carrier Proteins; Female; Guinea Pigs; Hydrogen; Hydrogen-Ion Concen

1999
Cardioprotection of SM-15681, an Na+/H+ exchange inhibitor in ischemic and hypoxic isolated perfused rat hearts.
    International journal of tissue reactions, 1999, Volume: 21, Issue:3

    Topics: Amides; Amiloride; Animals; Anti-Arrhythmia Agents; Hydrogen; Indoles; Ion Transport; Myocardial Isc

1999
Quantification and imaging of myocardial sodium and creatine kinase metabolites.
    Magma (New York, N.Y.), 2000, Volume: 11, Issue:1-2

    Topics: Adenosine Triphosphate; Creatine Kinase; Humans; Hydrogen; Magnetic Resonance Imaging; Magnetic Reso

2000
Effects of Na+/H+ exchange inhibitors in cardiac ischemia.
    Journal of molecular and cellular cardiology, 1992, Volume: 24, Issue:7

    Topics: Amiloride; Animals; Carrier Proteins; Erythrocytes; Hydrogen; In Vitro Techniques; Ion Transport; Ma

1992
Possible involvement of Na(+)-H+ exchange in the early phase of reperfusion in myocardial stunning.
    The Journal of surgical research, 1992, Volume: 53, Issue:5

    Topics: Amiloride; Animals; Calcium; Cardiac Output; Carrier Proteins; Coronary Circulation; Creatine Kinase

1992