Page last updated: 2024-10-18

hydrogen and Graft-Versus-Host Disease

hydrogen has been researched along with Graft-Versus-Host Disease in 8 studies

Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.

Research Excerpts

ExcerptRelevanceReference
"Hydrogen has been reported to have the ability to inhibit levels of cytokines such as TNF, IL-6 in vivo."5.39Hydrogen therapy may be an effective and specific novel treatment for acute graft-versus-host disease (GVHD). ( Qian, L; Shen, J, 2013)
" Hydrogen showed great efficacy on cGVHD patients and long-term administration of hydrogen was not associated with significant toxic effects."1.56Hydrogen in Patients With Corticosteroid-Refractory/Dependent Chronic Graft-Versus-Host-Disease: A Single-Arm, Multicenter, Open-Label, Phase 2 Trial. ( Cen, J; Liu, M; Qian, L; Shen, J; Zhao, D, 2020)
"Hydrogen has potential as an effective and safe therapeutic agent in aGVHD."1.42Administration of hydrogen-rich saline in mice with allogeneic hematopoietic stem-cell transplantation. ( Cai, J; Chen, X; Qian, L; Shen, J; Yuan, L, 2015)
"Hydrogen has been reported to have the ability to inhibit levels of cytokines such as TNF, IL-6 in vivo."1.39Hydrogen therapy may be an effective and specific novel treatment for acute graft-versus-host disease (GVHD). ( Qian, L; Shen, J, 2013)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (62.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Qian, L6
Liu, J1
Ma, W1
Liu, Y1
Wang, X1
Liu, D1
Liu, M1
Shen, J6
Cen, J1
Zhao, D2
Liu, X1
Yin, W1
Mei, K1
Cai, J2
Yuan, L2
Chen, X1
Oehme, J1
Hundeshagen, H1
Eschenbach, C1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Therapeutic Effects of Hydrogen on Steroid-refractory/or Steroid-dependent Chronic Graft-versus-host-disease[NCT02918188]Phase 221 participants (Anticipated)Interventional2016-01-31Recruiting
Hydrogen-Rich Celsior Solution Improve the Quality of Aging DBD Grafts in Liver/Kidney Transplantation: Prospective, Randomized Clinical Trial[NCT02613195]Phase 320 participants (Anticipated)Interventional2016-01-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for hydrogen and Graft-Versus-Host Disease

ArticleYear
Hydrogen, a potential safeguard for graft-versus-host disease and graft ischemia-reperfusion injury?
    Clinics (Sao Paulo, Brazil), 2016, Volume: 71, Issue:9

    Topics: Animals; Antioxidants; Cytokines; Graft vs Host Disease; Hydrogen; Organ Transplantation; Oxidative

2016

Other Studies

7 other studies available for hydrogen and Graft-Versus-Host Disease

ArticleYear
Hydrogen-Rich Water Ameliorates Murine Chronic Graft-versus-Host Disease through Antioxidation.
    Oxidative medicine and cellular longevity, 2021, Volume: 2021

    Topics: Animals; Antioxidants; Disease Models, Animal; Graft vs Host Disease; Hydrogen; Male; Mice; Water

2021
Hydrogen in Patients With Corticosteroid-Refractory/Dependent Chronic Graft-Versus-Host-Disease: A Single-Arm, Multicenter, Open-Label, Phase 2 Trial.
    Frontiers in immunology, 2020, Volume: 11

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Child; Chronic Disease; Drug Resistance; Female; Graft v

2020
Therapeutic effects of hydrogen on chronic graft-versus-host disease.
    Journal of cellular and molecular medicine, 2017, Volume: 21, Issue:10

    Topics: Animals; Bone Marrow Transplantation; Chronic Disease; Disease Models, Animal; Graft vs Host Disease

2017
Administration of hydrogen-rich saline protects mice from lethal acute graft-versus-host disease (aGVHD).
    Transplantation, 2013, Mar-15, Volume: 95, Issue:5

    Topics: Acute Disease; Animals; Bone Marrow Transplantation; Cytokines; Female; Graft vs Host Disease; Hydro

2013
Hydrogen therapy may be an effective and specific novel treatment for acute graft-versus-host disease (GVHD).
    Journal of cellular and molecular medicine, 2013, Volume: 17, Issue:8

    Topics: Acute Disease; Animals; Cell Death; Down-Regulation; Graft vs Host Disease; Hydrogen; Mice; Models,

2013
Administration of hydrogen-rich saline in mice with allogeneic hematopoietic stem-cell transplantation.
    Medical science monitor : international medical journal of experimental and clinical research, 2015, Mar-12, Volume: 21

    Topics: Animals; Cytokines; Gastrointestinal Tract; Graft vs Host Disease; Hematopoietic Stem Cell Transplan

2015
[On the passage of labelled leukocytes from the pregnant animal to the fetus--with a contribution on runt disease].
    Klinische Wochenschrift, 1966, Apr-15, Volume: 44, Issue:8

    Topics: Animals; Autoradiography; Female; Graft vs Host Disease; Hydrogen; Leukocytes; Liver; Lung; Maternal

1966