Page last updated: 2024-10-18

hydrogen and Gastroesophageal Reflux

hydrogen has been researched along with Gastroesophageal Reflux in 11 studies

Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.

Gastroesophageal Reflux: Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER.

Research Excerpts

ExcerptRelevanceReference
"The aim of the study is to investigate the frequency of pathological hydrogen breath tests (HBT) in patients with clinical features of functional dyspepsia (FD) meeting the Rome criteria and normal testing of upper endoscopy and abdominal sonography."7.91High Prevalence of Pathological Hydrogen Breath Tests in Patients with Functional Dyspepsia. ( Amanzada, A; Ellenrieder, V; Gress, TM; Kunsch, S; Neesse, A; Petzold, G, 2019)
"Gastroesophageal reflux disease (GERD), a clinical condition characterized by reflux of gastroduodenal contents in the oesophagus, has proved to demonstrate a strong link between oxidative stress and the development of GERD."6.87Modulation of the oxidative plasmatic state in gastroesophageal reflux disease with the addition of rich water molecular hydrogen: A new biological vision. ( De Lutiis, MA; Di Martino, G; Di Nicola, M; Felaco, M; Ferrone, A; Franceschelli, S; Gatta, DMP; Grilli, A; Patruno, A; Pesce, M; Speranza, L; Vitacolonna, E, 2018)
" This study investigated the effects of colonic fermentation induced by oral administration of fructooligosaccharides (FOS) in patients with gastroesophageal reflux disease (GERD)."5.10Colonic fermentation influences lower esophageal sphincter function in gastroesophageal reflux disease. ( Cuber, JC; des Varannes, SB; Galmiche, JP; Holst, JJ; Piche, T; Sacher-Huvelin, S, 2003)
"The aim of the study is to investigate the frequency of pathological hydrogen breath tests (HBT) in patients with clinical features of functional dyspepsia (FD) meeting the Rome criteria and normal testing of upper endoscopy and abdominal sonography."3.91High Prevalence of Pathological Hydrogen Breath Tests in Patients with Functional Dyspepsia. ( Amanzada, A; Ellenrieder, V; Gress, TM; Kunsch, S; Neesse, A; Petzold, G, 2019)
"We found no relationship between gastroesophageal reflux, age of patients, duration of disease, and Raynaud's phenomenon."1.31Twenty-four hour intraesophageal pH monitoring in children and adolescents with scleroderma and mixed connective tissue disease. ( Frosch, M; Ganser, G; Hülskamp, G; Roth, J; Weber, P; Zimmer, KP, 2000)
"Gastro-oesophageal reflux was assessed performing an ambulatory pH metering of the distal oesophagus over a period of 10 h with and without ortheses on two separate study days."1.29[The effect of lumbar relief orthoses with abdominal compression on esophago-gastrointestinal motility]. ( Adamek, RJ; Grifka, J; Pfaffenbach, B; Schleyer, S; Wegener, M, 1996)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's3 (27.27)18.2507
2000's3 (27.27)29.6817
2010's4 (36.36)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Franceschelli, S1
Gatta, DMP1
Pesce, M1
Ferrone, A1
Di Martino, G1
Di Nicola, M1
De Lutiis, MA1
Vitacolonna, E1
Patruno, A1
Grilli, A1
Felaco, M1
Speranza, L1
Petzold, G1
Amanzada, A1
Gress, TM1
Ellenrieder, V1
Neesse, A1
Kunsch, S1
Lombardo, L1
Foti, M1
Ruggia, O1
Chiecchio, A1
Okamoto, N1
Nambu, T1
Matsuda, Y1
Matsuo, K1
Osaki, K1
Kanai, Y1
Ogawa, Y1
Yonemitsu, S1
Kita, R1
Muro, S1
Sugawara, A1
Oki, S1
Piche, T1
des Varannes, SB1
Sacher-Huvelin, S1
Holst, JJ1
Cuber, JC1
Galmiche, JP1
Tolia, V1
Wuerth, A1
Thomas, R1
Freund, PR1
Radke, HM1
Kahrilas, PJ1
Quigley, EM1
Pfaffenbach, B1
Adamek, RJ1
Schleyer, S1
Grifka, J1
Wegener, M1
Weber, P1
Ganser, G1
Frosch, M1
Roth, J1
Hülskamp, G1
Zimmer, KP1
Mela, GS1
Savarino, V1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Retrospective Analysis of Treatment Outcomes in Patients With Bacterial Overgrowth Syndrome Diagnosed by D-Xylose Breath Testing[NCT01324895]944 participants (Actual)Observational2010-08-31Completed
Study on Dietary Nutrition Intervention Techniques for Children Obesity[NCT02539836]90 participants (Actual)Interventional2015-09-01Completed
Diagnosis of Acid Reflux Disease Using Novel Imaging: A Prospective Study[NCT02081404]98 participants (Actual)Interventional2009-03-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for hydrogen and Gastroesophageal Reflux

ArticleYear
Clinical esophageal pH recording: a technical review for practice guideline development.
    Gastroenterology, 1996, Volume: 110, Issue:6

    Topics: Ambulatory Care; Esophagus; Gastroesophageal Reflux; Humans; Hydrogen; Hydrogen-Ion Concentration; P

1996

Trials

2 trials available for hydrogen and Gastroesophageal Reflux

ArticleYear
Modulation of the oxidative plasmatic state in gastroesophageal reflux disease with the addition of rich water molecular hydrogen: A new biological vision.
    Journal of cellular and molecular medicine, 2018, Volume: 22, Issue:5

    Topics: Adult; Aged; Antioxidants; Gastroesophageal Reflux; Humans; Hydrogen; Middle Aged; Oxidation-Reducti

2018
Colonic fermentation influences lower esophageal sphincter function in gastroesophageal reflux disease.
    Gastroenterology, 2003, Volume: 124, Issue:4

    Topics: Administration, Oral; Adult; Breath Tests; Cholecystokinin; Colon; Cross-Over Studies; Diet; Esophag

2003

Other Studies

8 other studies available for hydrogen and Gastroesophageal Reflux

ArticleYear
High Prevalence of Pathological Hydrogen Breath Tests in Patients with Functional Dyspepsia.
    Digestion, 2019, Volume: 100, Issue:3

    Topics: Administration, Oral; Adult; Breath Tests; Crohn Disease; Diagnosis, Differential; Dyspepsia; Feasib

2019
Increased incidence of small intestinal bacterial overgrowth during proton pump inhibitor therapy.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2010, Volume: 8, Issue:6

    Topics: Adult; Anti-Bacterial Agents; Bacteria; Blind Loop Syndrome; Breath Tests; Female; Gastroesophageal

2010
Distal renal tubular acidosis that became exacerbated by proton pump inhibitor use.
    Internal medicine (Tokyo, Japan), 2012, Volume: 51, Issue:18

    Topics: Acidosis, Renal Tubular; Female; Gastroesophageal Reflux; H(+)-K(+)-Exchanging ATPase; Homeostasis;

2012
Diagnostic interpretation of extended pH monitoring: is there a single best method?
    Digestive diseases and sciences, 2005, Volume: 50, Issue:1

    Topics: Area Under Curve; Female; Gastroesophageal Reflux; Humans; Hydrogen; Hydrogen-Ion Concentration; Inf

2005
Intraoperative explosion: methane gas and diet.
    Anesthesiology, 1981, Volume: 55, Issue:6

    Topics: Dietary Carbohydrates; Dietary Proteins; Electrosurgery; Explosions; Gastroesophageal Reflux; Humans

1981
[The effect of lumbar relief orthoses with abdominal compression on esophago-gastrointestinal motility].
    Deutsche medizinische Wochenschrift (1946), 1996, Dec-20, Volume: 121, Issue:51-52

    Topics: Adult; Aged; Aged, 80 and over; Breath Tests; Coloring Agents; Esophagus; Female; Gastroesophageal R

1996
Twenty-four hour intraesophageal pH monitoring in children and adolescents with scleroderma and mixed connective tissue disease.
    The Journal of rheumatology, 2000, Volume: 27, Issue:11

    Topics: Adolescent; Child; Child, Preschool; Esophagus; Female; Gastroesophageal Reflux; Humans; Hydrogen; H

2000
Doubt on pH-metry as an absolute gold standard for measuring acid gastroesophageal reflux.
    Digestive diseases and sciences, 1990, Volume: 35, Issue:2

    Topics: Gastroesophageal Reflux; Humans; Hydrogen; Monitoring, Physiologic; Reproducibility of Results

1990