Page last updated: 2024-10-18

hydrogen and Fibrosis

hydrogen has been researched along with Fibrosis in 12 studies

Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.

Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.

Research Excerpts

ExcerptRelevanceReference
" hepaticus hydrogenase promoted liver inflammation and fibrosis development mediated by oxidative stress in male BALB/c mice."8.31Helicobacter hepaticus promotes liver fibrosis through oxidative stress induced by hydrogenase in BALB/c mice. ( Bao, R; Cao, S; Wang, T; Zhang, Q; Zhang, Y; Zhu, L, 2023)
"Previous studies have shown that hydrogen can antagonize the fibrosis of various organs."8.12Attenuation of Myocardial Fibrosis Using Molecular Hydrogen by Inhibiting the TGF-β Signaling Pathway in Spontaneous Hypertensive Rats. ( Li, X; Li, Y; Liu, L; Liu, X; Shi, Q, 2022)
"Oral intake of hydrogen-rich water (HW) can reduce oxidative stress and suppress interstitial fibrosis in unilateral ureteral obstruction-induced renal injury in rats."8.12Hydrogen-rich water reduced oxidative stress and renal fibrosis in rats with unilateral ureteral obstruction. ( Endo, A; Fujinaga, S; Hara, T; Hirano, D; Mizutani, A; Murano, Y; Nakagawa, M; Nishizaki, N; Ohtomo, Y; Saito, M; Sakuraya, K; Shimizu, T, 2022)
"The current research was designed to study the role of hydrogen in renal fibrosis and the renal epithelial to mesenchymal transition (EMT) induced by transforming growth factor-β1 (TGF-β1)."7.85Hydrogen Rich Water Attenuates Renal Injury and Fibrosis by Regulation Transforming Growth Factor-β Induced Sirt1. ( Fan, M; He, X; Pan, W; Xing, Z; Xu, X; Zhang, J; Zhang, X, 2017)
" The present study investigated the effects of hydrogen-rich saline, a selective hydroxyl radical scavenger, on lipopolysaccharide (LPS)-induced pulmonary fibrosis."7.85Protective Effects of Hydrogen-Rich Saline Against Lipopolysaccharide-Induced Alveolar Epithelial-to-Mesenchymal Transition and Pulmonary Fibrosis. ( Dong, WW; Jiang, L; Liu, YJ; Mao, YF; Sun, XJ; Zhang, YQ; Zhu, XY, 2017)
"Hydrogen is a novel medical gas with several properties, including anti-oxidative, anti-inflammatory, anti-apoptotic, anti-allergic, and energy metabolism stimulating properties."5.72Co-administration of hydrogen and metformin exerts cardioprotective effects by inhibiting pyroptosis and fibrosis in diabetic cardiomyopathy. ( Bai, J; Hong, X; Liu, J; Nie, C; Pan, S; Wang, B; Xi, S; Yang, W; Yu, M; Zou, R, 2022)
"The cardiac hypertrophy was also manifested with increased expressions of atrial natriuretic peptide (ANP), brain natriuretic peptides (BNP) and fibrosis of cardiac tissues in AAC-model group, which could likewise be restrained in LHRS and HHRS groups."5.48Protective effect of hydrogen-rich saline on pressure overload-induced cardiac hypertrophyin rats: possible role of JAK-STAT signaling. ( Fan, Z; Fu, L; Gao, Y; Huang, Z; Wu, S; Xue, F; Yang, J; Zhu, L, 2018)
"Hydrogen has been demonstrated to have effective protection against tissue injuries caused by oxidative stress, inflammation, and apoptosis."5.39Hydrogen-rich saline ameliorates renal injury induced by unilateral ureteral obstruction in rats. ( Jiang, DP; Li, ZZ; Wang, S; Xu, B; Yang, MW; Zhang, YB, 2013)
" hepaticus hydrogenase promoted liver inflammation and fibrosis development mediated by oxidative stress in male BALB/c mice."4.31Helicobacter hepaticus promotes liver fibrosis through oxidative stress induced by hydrogenase in BALB/c mice. ( Bao, R; Cao, S; Wang, T; Zhang, Q; Zhang, Y; Zhu, L, 2023)
"Previous studies have shown that hydrogen can antagonize the fibrosis of various organs."4.12Attenuation of Myocardial Fibrosis Using Molecular Hydrogen by Inhibiting the TGF-β Signaling Pathway in Spontaneous Hypertensive Rats. ( Li, X; Li, Y; Liu, L; Liu, X; Shi, Q, 2022)
"Oral intake of hydrogen-rich water (HW) can reduce oxidative stress and suppress interstitial fibrosis in unilateral ureteral obstruction-induced renal injury in rats."4.12Hydrogen-rich water reduced oxidative stress and renal fibrosis in rats with unilateral ureteral obstruction. ( Endo, A; Fujinaga, S; Hara, T; Hirano, D; Mizutani, A; Murano, Y; Nakagawa, M; Nishizaki, N; Ohtomo, Y; Saito, M; Sakuraya, K; Shimizu, T, 2022)
"The current research was designed to study the role of hydrogen in renal fibrosis and the renal epithelial to mesenchymal transition (EMT) induced by transforming growth factor-β1 (TGF-β1)."3.85Hydrogen Rich Water Attenuates Renal Injury and Fibrosis by Regulation Transforming Growth Factor-β Induced Sirt1. ( Fan, M; He, X; Pan, W; Xing, Z; Xu, X; Zhang, J; Zhang, X, 2017)
" The present study investigated the effects of hydrogen-rich saline, a selective hydroxyl radical scavenger, on lipopolysaccharide (LPS)-induced pulmonary fibrosis."3.85Protective Effects of Hydrogen-Rich Saline Against Lipopolysaccharide-Induced Alveolar Epithelial-to-Mesenchymal Transition and Pulmonary Fibrosis. ( Dong, WW; Jiang, L; Liu, YJ; Mao, YF; Sun, XJ; Zhang, YQ; Zhu, XY, 2017)
"Hydrogen is a novel medical gas with several properties, including anti-oxidative, anti-inflammatory, anti-apoptotic, anti-allergic, and energy metabolism stimulating properties."1.72Co-administration of hydrogen and metformin exerts cardioprotective effects by inhibiting pyroptosis and fibrosis in diabetic cardiomyopathy. ( Bai, J; Hong, X; Liu, J; Nie, C; Pan, S; Wang, B; Xi, S; Yang, W; Yu, M; Zou, R, 2022)
"The cardiac hypertrophy was also manifested with increased expressions of atrial natriuretic peptide (ANP), brain natriuretic peptides (BNP) and fibrosis of cardiac tissues in AAC-model group, which could likewise be restrained in LHRS and HHRS groups."1.48Protective effect of hydrogen-rich saline on pressure overload-induced cardiac hypertrophyin rats: possible role of JAK-STAT signaling. ( Fan, Z; Fu, L; Gao, Y; Huang, Z; Wu, S; Xue, F; Yang, J; Zhu, L, 2018)
"Hydrogen has been demonstrated to have effective protection against tissue injuries caused by oxidative stress, inflammation, and apoptosis."1.39Hydrogen-rich saline ameliorates renal injury induced by unilateral ureteral obstruction in rats. ( Jiang, DP; Li, ZZ; Wang, S; Xu, B; Yang, MW; Zhang, YB, 2013)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's6 (50.00)24.3611
2020's4 (33.33)2.80

Authors

AuthorsStudies
Liu, L1
Shi, Q1
Liu, X1
Li, Y1
Li, X1
Zou, R1
Nie, C1
Pan, S1
Wang, B1
Hong, X1
Xi, S1
Bai, J1
Yu, M1
Liu, J1
Yang, W1
Cao, S1
Zhang, Y1
Bao, R1
Wang, T1
Zhu, L3
Zhang, Q1
Mizutani, A1
Endo, A1
Saito, M1
Hara, T1
Nakagawa, M1
Sakuraya, K1
Murano, Y1
Nishizaki, N1
Hirano, D1
Fujinaga, S1
Ohtomo, Y1
Shimizu, T1
Xing, Z1
Pan, W1
Zhang, J1
Xu, X1
Zhang, X1
He, X1
Fan, M1
Dong, WW1
Zhang, YQ1
Zhu, XY1
Mao, YF1
Sun, XJ1
Liu, YJ1
Jiang, L1
Yang, J2
Wu, S2
Cai, J1
Fu, L2
Fan, Z1
Gao, Y1
Huang, Z1
Xue, F1
Xu, B1
Zhang, YB1
Li, ZZ1
Yang, MW1
Wang, S1
Jiang, DP1
Hayashi, T1
Yoshioka, T1
Hasegawa, K1
Miyamura, M1
Mori, T1
Ukimura, A1
Matsumura, Y1
Ishizaka, N1
Young, M1
Funder, J1
Dunlap, J1
Manske, PR1
McCarthy, JA1

Other Studies

12 other studies available for hydrogen and Fibrosis

ArticleYear
Attenuation of Myocardial Fibrosis Using Molecular Hydrogen by Inhibiting the TGF-β Signaling Pathway in Spontaneous Hypertensive Rats.
    American journal of hypertension, 2022, 02-01, Volume: 35, Issue:2

    Topics: Angiotensin II; Animals; Cardiomyopathies; Collagen Type I; Fibrosis; Hydrogen; Myocardium; Procolla

2022
Co-administration of hydrogen and metformin exerts cardioprotective effects by inhibiting pyroptosis and fibrosis in diabetic cardiomyopathy.
    Free radical biology & medicine, 2022, Volume: 183

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Fibrosis; Hydrogen; Metformin;

2022
Helicobacter hepaticus promotes liver fibrosis through oxidative stress induced by hydrogenase in BALB/c mice.
    Helicobacter, 2023, Volume: 28, Issue:5

    Topics: Animals; Fibrosis; Helicobacter hepaticus; Helicobacter Infections; Helicobacter pylori; Hydrogen; H

2023
Hydrogen-rich water reduced oxidative stress and renal fibrosis in rats with unilateral ureteral obstruction.
    Pediatric research, 2022, Volume: 91, Issue:7

    Topics: Adolescent; Animals; Fibrosis; Humans; Hydrogen; Kidney; Kidney Diseases; Male; Oxidative Stress; Ra

2022
Hydrogen Rich Water Attenuates Renal Injury and Fibrosis by Regulation Transforming Growth Factor-β Induced Sirt1.
    Biological & pharmaceutical bulletin, 2017, Volume: 40, Issue:5

    Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Cell Line; Creatinine; Fibrosis; Humans; Hydrogen

2017
Protective Effects of Hydrogen-Rich Saline Against Lipopolysaccharide-Induced Alveolar Epithelial-to-Mesenchymal Transition and Pulmonary Fibrosis.
    Medical science monitor : international medical journal of experimental and clinical research, 2017, May-19, Volume: 23

    Topics: Animals; Cadherins; Collagen; Collagen Type I; Epithelial Cells; Epithelial-Mesenchymal Transition;

2017
Hydrogen-containing saline alleviates pressure overload-induced interstitial fibrosis and cardiac dysfunction in rats.
    Molecular medicine reports, 2017, Volume: 16, Issue:2

    Topics: Animals; Electrocardiography; Enzyme Activation; Fibrosis; Gene Expression Regulation; Heart; Heart

2017
Protective effect of hydrogen-rich saline on pressure overload-induced cardiac hypertrophyin rats: possible role of JAK-STAT signaling.
    BMC cardiovascular disorders, 2018, 02-13, Volume: 18, Issue:1

    Topics: Animals; Aorta, Abdominal; Apoptosis; Arterial Pressure; Atrial Natriuretic Factor; Cardiomegaly; Co

2018
Hydrogen-rich saline ameliorates renal injury induced by unilateral ureteral obstruction in rats.
    International immunopharmacology, 2013, Volume: 17, Issue:2

    Topics: Acute Kidney Injury; Animals; Apoptosis; Cells, Cultured; Fibrosis; Humans; Hydrogen; Kidney; Macrop

2013
Inhalation of hydrogen gas attenuates left ventricular remodeling induced by intermittent hypoxia in mice.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 301, Issue:3

    Topics: Administration, Inhalation; Aldehydes; Analysis of Variance; Animals; Cholesterol, LDL; Cholesterol,

2011
Mineralocorticoid action and sodium-hydrogen exchange: studies in experimental cardiac fibrosis.
    Endocrinology, 2003, Volume: 144, Issue:9

    Topics: Animals; Anti-Arrhythmia Agents; Canrenoic Acid; Desoxycorticosterone; Fibrosis; Guanidines; Heart D

2003
Perfusion of the abductor digiti quinti after transfer on a neurovascular pedicle.
    The Journal of hand surgery, 1989, Volume: 14, Issue:6

    Topics: Animals; Fibrosis; Hydrogen; Ischemia; Macaca nemestrina; Muscles; Regional Blood Flow; Surgical Fla

1989