Page last updated: 2024-10-18

hydrogen and Fatty Liver, Nonalcoholic

hydrogen has been researched along with Fatty Liver, Nonalcoholic in 14 studies

Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.

Research Excerpts

ExcerptRelevanceReference
"This study was aimed to investigate the potential regulatory mechanism of high-content hydrogen water (HHW) in non-alcoholic fatty liver disease (NAFLD)."7.88High-content hydrogen water-induced downregulation of miR-136 alleviates non-alcoholic fatty liver disease by regulating Nrf2 via targeting MEG3. ( Wang, J; Wang, X, 2018)
"Twelve overweight outpatients with NAFLD (age 56."6.90Hydrogen-rich water reduces liver fat accumulation and improves liver enzyme profiles in patients with non-alcoholic fatty liver disease: a randomized controlled pilot trial. ( Korovljev, D; LeBaron, TW; Ostojic, J; Ostojic, SM; Stajer, V, 2019)
"Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy."4.40Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023)
"This study was aimed to investigate the potential regulatory mechanism of high-content hydrogen water (HHW) in non-alcoholic fatty liver disease (NAFLD)."3.88High-content hydrogen water-induced downregulation of miR-136 alleviates non-alcoholic fatty liver disease by regulating Nrf2 via targeting MEG3. ( Wang, J; Wang, X, 2018)
"Twelve overweight outpatients with NAFLD (age 56."2.90Hydrogen-rich water reduces liver fat accumulation and improves liver enzyme profiles in patients with non-alcoholic fatty liver disease: a randomized controlled pilot trial. ( Korovljev, D; LeBaron, TW; Ostojic, J; Ostojic, SM; Stajer, V, 2019)
"Hydrogen therapy is a very promising treatment against several diseases due to its mild attributes, high affinity and inherent biosafety."2.72Hydrogen treatment: a novel option in liver diseases. ( Duncan, B; Kuang, X; Shi, J, 2021)
"Fifty four patients with NAFLD at the stage of steatosis and steatohepatitis at the age of 1860 years were examined."1.72[The study of abdominal and parietal enteric microbiota in patients with non-alcoholic fatty liver disease]. ( Lukashevich, AP; Lyapina, MV; Vakhrushev, YM, 2022)
"Non-alcoholic fatty liver disease (NAFLD) comprises a range of liver diseases, between steatosis and non‑alcoholic steatohepatitis and liver cirrhosis, which are closely associated with diabetes mellitus."1.46Hydrogen-rich saline improves non‑alcoholic fatty liver disease by alleviating oxidative stress and activating hepatic PPARα and PPARγ. ( Chen, X; Huang, Q; Lu, J; Sun, X; Wang, Q; Zhai, X; Zhang, Y, 2017)
"Diet-induced nonalcoholic fatty liver disease (NAFLD) is characterized by profound lipid accumulation and associated with an inflammatory response, oxidative stress and hepatic mitochondrial dysfunction."1.43Coral calcium hydride prevents hepatic steatosis in high fat diet-induced obese rats: A potent mitochondrial nutrient and phase II enzyme inducer. ( Feng, Z; Hou, C; Liu, J; Long, J; Qiu, Y; Shen, H; Sun, X; Wang, X; Wang, Y; Yan, C; Zhao, L; Zhu, E, 2016)
"Children with histologically proven NAFLD, and obese and lean controls received oral fructose (1 g kg(-1) ideal body weight)."1.42Oral fructose absorption in obese children with non-alcoholic fatty liver disease. ( Johnson, RJ; Le, MT; Love-Osborne, K; Pan, Z; Rivard, C; Robbins, K; Sokol, RJ; Sullivan, JS; Sundaram, SS, 2015)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (50.00)24.3611
2020's7 (50.00)2.80

Authors

AuthorsStudies
Kim, H1
Bartley, GE1
Young, SA1
Seo, KH1
Yokoyama, W1
Tao, G1
Zhang, G1
Chen, W1
Yang, C1
Xue, Y1
Song, G1
Qin, S3
Vakhrushev, YM1
Lukashevich, AP1
Lyapina, MV1
Zhao, M2
Jin, Z1
Xia, C1
Chen, S1
Zeng, L1
He, Q1
Sicchieri, JMF1
Junqueira, G1
Manca, CS1
Navarro, AM1
de Oliveira, RB1
Liu, B1
Xue, J1
Zhang, M1
Wang, M1
Ma, T1
Gu, Q1
Shi, J1
Duncan, B1
Kuang, X1
Wang, X2
Wang, J1
Korovljev, D1
Stajer, V1
Ostojic, J1
LeBaron, TW1
Ostojic, SM1
Sullivan, JS1
Le, MT1
Pan, Z1
Rivard, C1
Love-Osborne, K1
Robbins, K1
Johnson, RJ1
Sokol, RJ1
Sundaram, SS1
Hou, C1
Wang, Y1
Zhu, E1
Yan, C1
Zhao, L1
Qiu, Y1
Shen, H1
Sun, X2
Feng, Z1
Liu, J1
Long, J1
Zhai, X1
Chen, X1
Lu, J1
Zhang, Y1
Huang, Q1
Wang, Q1
Kawai, D1
Takaki, A1
Nakatsuka, A1
Wada, J1
Tamaki, N1
Yasunaka, T1
Koike, K1
Tsuzaki, R1
Matsumoto, K1
Miyake, Y1
Shiraha, H1
Morita, M1
Makino, H1
Yamamoto, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Hydrogen-rich Water on Liver Fat Accumulation, Blood Lipids and Body Fatness in Patients With Non-alchoholic Fatty Liver Disease[NCT03625362]10 participants (Actual)Interventional2018-09-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for hydrogen and Fatty Liver, Nonalcoholic

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Hydrogen treatment: a novel option in liver diseases.
    Clinical medicine (London, England), 2021, Volume: 21, Issue:2

    Topics: Apoptosis; Humans; Hydrogen; Liver; Liver Neoplasms; Non-alcoholic Fatty Liver Disease

2021

Trials

3 trials available for hydrogen and Fatty Liver, Nonalcoholic

ArticleYear
A randomized, placebo-controlled clinical trial of hydrogen/oxygen inhalation for non-alcoholic fatty liver disease.
    Journal of cellular and molecular medicine, 2022, Volume: 26, Issue:14

    Topics: Animals; Anti-Inflammatory Agents; Diabetes Mellitus, Type 2; Humans; Hydrogen; Liver; Mice; Mice, I

2022
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Hydrogen-rich water reduces liver fat accumulation and improves liver enzyme profiles in patients with non-alcoholic fatty liver disease: a randomized controlled pilot trial.
    Clinics and research in hepatology and gastroenterology, 2019, Volume: 43, Issue:6

    Topics: Adipose Tissue; Aged; Body Composition; Cross-Over Studies; Double-Blind Method; Female; Humans; Hyd

2019

Other Studies

10 other studies available for hydrogen and Fatty Liver, Nonalcoholic

ArticleYear
Altered hepatic gene expression profiles associated with improved fatty liver, insulin resistance, and intestinal permeability after hydroxypropyl methylcellulose (HPMC) supplementation in diet-induced obese mice.
    Journal of agricultural and food chemistry, 2013, Jul-03, Volume: 61, Issue:26

    Topics: Animals; Cellulose; Diet, High-Fat; Fatty Liver; Gene Expression Profiling; Gene Expression Regulati

2013
[The study of abdominal and parietal enteric microbiota in patients with non-alcoholic fatty liver disease].
    Terapevticheskii arkhiv, 2022, Feb-15, Volume: 94, Issue:2

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Bacteria; Humans; Hydrogen; Intestine, Small; Lac

2022
Inhibition of free heme-catalyzed Fenton-like reaction prevents non-alcoholic fatty liver disease by hepatocyte-targeted hydrogen delivery.
    Biomaterials, 2023, Volume: 301

    Topics: Animals; Hepatocytes; Hydrogen; Hydrogen Peroxide; Iron; Liver; Mice; Non-alcoholic Fatty Liver Dise

2023
High intestinal hydrogen production in runners after intake of fructose solution.
    Journal of breath research, 2020, 08-14, Volume: 14, Issue:4

    Topics: Adult; Female; Fructose; Humans; Hydrogen; Intestines; Male; Non-alcoholic Fatty Liver Disease; Runn

2020
Hydrogen inhalation alleviates nonalcoholic fatty liver disease in metabolic syndrome rats.
    Molecular medicine reports, 2020, Volume: 22, Issue:4

    Topics: Administration, Inhalation; Animals; Body Mass Index; Diet, Carbohydrate Loading; Diet, High-Fat; Di

2020
High-content hydrogen water-induced downregulation of miR-136 alleviates non-alcoholic fatty liver disease by regulating Nrf2 via targeting MEG3.
    Biological chemistry, 2018, 03-28, Volume: 399, Issue:4

    Topics: Animals; Cell Line; Cell Survival; Down-Regulation; Hydrogen; Male; Mice; Mice, Inbred C57BL; MicroR

2018
Oral fructose absorption in obese children with non-alcoholic fatty liver disease.
    Pediatric obesity, 2015, Volume: 10, Issue:3

    Topics: Adolescent; Biomarkers; Blood Glucose; Body Mass Index; Breath Tests; Child; Eating; Female; Fructos

2015
Coral calcium hydride prevents hepatic steatosis in high fat diet-induced obese rats: A potent mitochondrial nutrient and phase II enzyme inducer.
    Biochemical pharmacology, 2016, Mar-01, Volume: 103

    Topics: Animals; Anthozoa; Body Weight; Calcium Compounds; Dietary Fats; Eating; Enzyme Induction; Glucose;

2016
Hydrogen-rich saline improves non‑alcoholic fatty liver disease by alleviating oxidative stress and activating hepatic PPARα and PPARγ.
    Molecular medicine reports, 2017, Volume: 15, Issue:3

    Topics: Animals; Biomarkers; Caspase 3; Glucose Tolerance Test; Hydrogen; Insulin Resistance; Male; Non-alco

2017
Hydrogen-rich water prevents progression of nonalcoholic steatohepatitis and accompanying hepatocarcinogenesis in mice.
    Hepatology (Baltimore, Md.), 2012, Volume: 56, Issue:3

    Topics: Animals; Disease Progression; Fatty Liver; Hydrogen; Hypoglycemic Agents; Liver Neoplasms; Male; Mic

2012