hydrogen has been researched along with Disease Models, Animal in 233 studies
Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although hydrogen has been proved to be a novel therapeutic medical gas in several lung injury animal models, to our knowledge, it has not been tested yet in acute lung injury (ALI) induced by cecal ligation and puncture (CLP)." | 8.91 | Hydrogen-rich saline ameliorates lung injury associated with cecal ligation and puncture-induced sepsis in rats. ( Dai, Q; Fan, Y; Huang, X; Zhai, Y; Zhou, X, 2015) |
| "The aim of this study was to investigate the efficacy and underlying mechanism of high concentration of hydrogen on lipopolysaccharide (LPS)-induced acute lung injury (ALI)." | 8.12 | High concentration of hydrogen ameliorates lipopolysaccharide-induced acute lung injury in a sirt1-dependent manner. ( Du, J; Li, J; Li, R; Yan, X, 2022) |
| "Hydrogen-rich water partially alleviates inflammation, oxidative stress and intestinal flora dysbiosis in DSS-induced chronic UC mice." | 8.12 | Hydrogen-rich water partially alleviate inflammation, oxidative stress and intestinal flora dysbiosis in DSS-induced chronic ulcerative colitis mice. ( Ding, X; Song, L; Yan, H; Yang, L; Zhang, Y; Zhu, C, 2022) |
| "Many studies have demonstrated the therapeutic effects of hydrogen in pathological conditions such as inflammation; however, little is known about its prophylactic effects." | 8.12 | Prophylactic Instillation of Hydrogen-Rich Water Decreases Corneal Inflammation and Promotes Wound Healing by Activating Antioxidant Activity in a Rat Alkali Burn Model. ( Arima, T; Ikebukuro, T; Kasamatsu, M; Nakano, Y; Shimizu, A; Takahashi, H; Tobita, Y; Uchiyama, M, 2022) |
| "This experimental study aimed to assess the efficacy of hydrogen gas inhalation against spinal cord ischemia-reperfusion injury and reveal its mechanism by measuring glutamate concentration in the ventral horn using an in vivo microdialysis method." | 8.12 | Protective effects of hydrogen gas against spinal cord ischemia-reperfusion injury. ( Fujimoto, Y; Funao, T; Kimura, A; Mori, T; Mukai, A; Suehiro, K; Yamada, T, 2022) |
| "Hydrogen treatment could potentially be a future therapeutic strategy for ischemia and its derived neurodegenerative diseases by improving cognitive abilities and inducing antioxidative and antiapoptotic effects." | 8.02 | Hydrogen-Rich Water Improves Cognitive Ability and Induces Antioxidative, Antiapoptotic, and Anti-Inflammatory Effects in an Acute Ischemia-Reperfusion Injury Mouse Model. ( Choi, JI; Lee, D, 2021) |
| "Hydrogen provided protection from organ injury induced by sepsis via autophagy activation and endoplasmic reticulum stress pathway inactivation." | 7.96 | Hydrogen alleviated organ injury and dysfunction in sepsis: The role of cross-talk between autophagy and endoplasmic reticulum stress: Experimental research. ( Chen, HG; Han, HZ; Li, Y; Xie, KL; Yu, YH, 2020) |
| "BACKGROUND The aim of this study was to investigate the mechanisms underlying the potential effects of hydrogen-rich water (HW) on articular cartilage in a rat osteoarthritis (OA) model." | 7.96 | Protective Effects of Hydrogen-Rich Water Against Cartilage Damage in a Rat Model of Osteoarthritis by Inhibiting Oxidative Stress, Matrix Catabolism, and Apoptosis. ( Chen, W; Chen, Y; Cheng, S; Gu, Y; Peng, L; Xu, B, 2020) |
| "This study was designed to investigate the effects of low concentration hydrogen inhalation on asthma and sleep function in mice and the potential mechanism." | 7.96 | [Effects of Low Concentration Hydrogen Inhalation on Asthma and Sleep Function in Mice]. ( Du, JR; Wei, L; Zhang, XW; Zhao, Y; Zhu, L, 2020) |
| "To investigate if hydrogen-rich saline (HRS), which has been shown to have antioxidant and anti-inflammatory properties, could mitigate cardiac remodelling and reduce the incidence of atrial fibrillation (AF) in the rat model of cardiac hypertrophy." | 7.96 | Hydrogen-rich saline mitigates pressure overload-induced cardiac hypertrophy and atrial fibrillation in rats via the JAK-STAT signalling pathway. ( Pan, Z; Wang, C, 2020) |
| "Hydrogen gas (H2) inhalation during hemorrhage stabilizes post-resuscitation hemodynamics, improving short-term survival in a rat hemorrhagic shock and resuscitation (HS/R) model." | 7.96 | Hydrogen Gas Inhalation Attenuates Endothelial Glycocalyx Damage and Stabilizes Hemodynamics in a Rat Hemorrhagic Shock Model. ( Endo, J; Homma, K; Kajimura, M; Katsumata, Y; Kobayashi, E; Matsuoka, T; Sano, M; Sasaki, J; Suzuki, M; Tamura, T; Yamamoto, R; Yoshizawa, J, 2020) |
| "In this asphyxial CA rat model, the improved postresuscitation EEG characteristics for animals treated with hydrogen are correlated with the better 96 h neurological outcome and predicted survival." | 7.91 | Inhaling Hydrogen Ameliorates Early Postresuscitation EEG Characteristics in an Asphyxial Cardiac Arrest Rat Model. ( Chen, B; Chen, G; Li, J; Li, Y; Wang, J, 2019) |
| " Hydrogen gas provides potent anti-inflammatory and antioxidant effects against ischemia-reperfusion injury (IRI)." | 7.91 | Protective effects of hydrogen inhalation during the warm ischemia phase against lung ischemia-reperfusion injury in rat donors after cardiac death. ( Deng, L; Li, W; Liu, J; Meng, C; Zhang, J; Zhou, H, 2019) |
| "Forty-five adult male Sprague Dawley rats (body weight 220-250 g) were randomly divided into three groups: (1) Sham operation group (SH), (2) Ischemia-reperfusion injury group (IR), and (3) Ischemia-reperfusion injury with preconditioning hydrogen group (PRH)." | 7.91 | Preconditioning with one-time hydrogen gas does not attenuate skin flap ischemia-reperfusion injury in rat models. ( Dong, X; Hao, Y; Liu, H; Wang, Y, 2019) |
| " In this study, we focused on the key factors responsible for bacterial translocation including the intestinal microbiome and investigated the impact of molecular hydrogen therapy as a countermeasure against bacterial translocation in a murine model of sepsis." | 7.88 | Hydrogen-Rich Saline Regulates Intestinal Barrier Dysfunction, Dysbiosis, and Bacterial Translocation in a Murine Model of Sepsis. ( Hirano, SI; Ichimaru, N; Ikeda, M; Kurakawa, T; Motooka, D; Nakamura, S; Ogura, H; Shimazu, T; Shimizu, K; Takahara, S; Takeda, K; Umemoto, E, 2018) |
| " This study aims to investigate the potential effects of hydrogen-rich saline (HRS) administration on naloxone-precipitated withdrawal symptoms and morphine withdrawal-induced anxiety-like behaviors." | 7.85 | Hydrogen-rich saline attenuates anxiety-like behaviors in morphine-withdrawn mice. ( Cong, B; Gong, M; Guo, H; Hui, R; Ma, C; Shen, Q; Wang, J; Wen, D; Zhao, P, 2017) |
| "Inhaled hydrogen gas (H2) provides protection in rat models of human acute lung injury (ALI)." | 7.85 | Protection by Inhaled Hydrogen Therapy in a Rat Model of Acute Lung Injury can be Tracked in vivo Using Molecular Imaging. ( Audi, SH; Camara, AKS; Clough, AV; Jacobs, ER; Medhora, MM; Rizzo, B; Zhang, X; Zhao, M, 2017) |
| "By using an L-arginine induced chronic pancreatitis mouse model, we tested the therapeutic potential of hydrogen, a strong hydroxyl radicals scavenger, in the chronic pancreatitis model." | 7.85 | Hydrogen Treatment Protects Mice Against Chronic Pancreatitis by Restoring Regulatory T Cells Loss. ( Bian, Y; Chen, L; Li, J; Lu, J; Ma, C; Su, L; Wang, T, 2017) |
| "The objective of this study was to investigate the protective effects of molecular hydrogen, a novel and selective antioxidant, on steroid-induced osteonecrosis (ON) in a rabbit model." | 7.85 | Protective effects of molecular hydrogen on steroid-induced osteonecrosis in rabbits via reducing oxidative stress and apoptosis. ( Fan, L; Ge, Z; Li, J; Wang, K, 2017) |
| "To investigate the role of Rho/ROCK signaling pathway in the protective effects of hydrogen gas (H2) on acute lung injury (ALI) in a mouse model of sepsis." | 7.83 | [Role of Rho/ROCK signaling pathway in the protective effects of hydrogen against acute lung injury in septic mice]. ( Liang, Y; Liu, L; Sun, Z; Yu, Y; Zhang, H, 2016) |
| "A single intraperitoneal dose of hydrogen-rich saline ameliorates postoperative ileus by inhibiting the inflammatory response and suppressing nitric oxide production." | 7.83 | Intraperitoneally administered, hydrogen-rich physiologic solution protects against postoperative ileus and is associated with reduced nitric oxide production. ( Aoyama-Ishikawa, M; Fujisaki, N; Iida, A; Kohama, K; Kotani, J; Naito, H; Nakao, A; Nosaka, N; Okamoto, A; Sato, K; Tsukahara, K; Yamada, T; Yamashita, H; Yumoto, T, 2016) |
| " Therefore because oxidative stress plays a significant role in the pathophysiology of myocardial infarction (MI), the aim of our study was to investigate whether hydrogen-rich saline has cardioprotective effects against isoproterenol-induced MI in rats." | 7.81 | Cardioprotective Effect of Hydrogen-rich Saline on Isoproterenol-induced Myocardial Infarction in Rats. ( Han, JJ; Jing, L; Qin, SC; Sun, XJ; Wang, Y; Zhao, B; Zhao, XM, 2015) |
| "To investigate the effects of hydrogen-rich saline on cardiomyocyte autophagy during myocardial ischemia-reperfusion in aged rats." | 7.81 | [Effect of hydrogen-rich saline on cardiomyocyte autophagy during myocardial ischemia-reperfusion in aged rats]. ( Liu, D; Pan, Z; Xu, H; Yu, H; Zhao, Y, 2015) |
| "Pretreatment by HRS ameliorated renal dysfunction in glycerol-induced rhabdomyolysis by inhibiting oxidative stress and the inflammatory response." | 7.80 | Pretreatment with hydrogen-rich saline reduces the damage caused by glycerol-induced rhabdomyolysis and acute kidney injury in rats. ( Gao, X; Gu, H; Sun, X; Yang, M; Zhao, B; Zhao, X, 2014) |
| "To explore the mechanism of hydrogen on the intervention of abdominal aortic aneurysm (AAA)." | 7.80 | [Suppression of abdominal aortic aneurysm by hydrogen through chemokine-like factor1]. ( Chen, F; Guo, W; Jia, S; Liu, J; Pan, X; Shen, C; Song, Y; Xiong, J; Zhang, T, 2014) |
| "To study the effect of hydrogen-rich water (HRW) on acute peritonitis with three different rat models." | 7.80 | Effect of hydrogen-rich water on acute peritonitis of rat models. ( Liu, C; Song, S; Tai, M; Wan, Y; Wu, Q; Zhang, J; Zhang, R, 2014) |
| "To investigate the role of Nrf2 on hydrogen treatment for intestinal injury caused by severe sepsis." | 7.80 | [The role of Nrf2 in the hydrogen treatment for intestinal injury caused by severe sepsis]. ( Chen, H; Li, Y; Wang, G; Wang, W; Xie, K; Yu, Y, 2014) |
| "Asthma was induced by ovalbumin (OVA) sensitization and challenge." | 7.79 | Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma. ( Wang, T; Wen, FQ; Xiao, M; Zhu, T, 2013) |
| "To investigate the effect of hydrogen inhalation on acute lung injury after hemorrhagic shock in rats." | 7.79 | [The effect of hydrogen on hemorrhagic shock induced acute lung injury in rats]. ( Jia, YR; Liu, JF; Shi, HM; Wang, Y; Zhou, HC, 2013) |
| "To investigate the effects of saturated hydrogen saline on the prevention of abdominal aortic aneurysm (AAA) induced by calcium chloride in a rat model." | 7.79 | [Suppression of experimental abdominal aortic aneurysm by saturated hydrogen saline: a preliminary study with rats]. ( Chen, F; Guo, W; Jia, SH; Liu, J; Pan, XJ; Song, YX; Xiong, J; Zhang, T, 2013) |
| "To determine the effect of saturated hydrogen saline on lipopolysaccharide (LPS)-induced acute liver dysfunction, rats were divided into control, LPS, and LPS plus saturated hydrogen saline (LPS+H(2)) groups." | 7.79 | Saturated hydrogen saline attenuates endotoxin-induced acute liver dysfunction in rats. ( Xu, XF; Zhang, J, 2013) |
| "By observation of the diameter, progression rate, wall thickness, and the opening angle of the abnormal aortic of abdominal aortic aneurysm (AAA) in rats, to observe the effect of saturated hydrogen saline on residual strain of AAA rats, and to investigate its inhibition effect on AAA formation." | 7.79 | [A study on residual strain of abdominal aortic aneurysm after intraperitoneal administration of saturated hydrogen saline in rats]. ( Chen, F; Guo, W; Jia, S; Liu, J; Pan, X; Song, Y; Xiong, J, 2013) |
| "Hydrogen-rich saline effectively improved erectile function in a streptozotocin induced diabetic rat model of erectile dysfunction." | 7.79 | Protective effects of hydrogen-rich saline against erectile dysfunction in a streptozotocin induced diabetic rat model. ( Chao, Z; Chen, L; Fan, M; He, X; Liu, J; Qian, L; Qing, J; Sun, X; Xu, X, 2013) |
| "Hydrogen saline may be a potential treatment for hyperoxia-induced retinopathy that acts via the inhibition of oxidative stress and the reduction of VEGF expression." | 7.78 | Hydrogen saline treatment attenuates hyperoxia-induced retinopathy by inhibition of oxidative stress and reduction of VEGF expression. ( Huang, L; Sun, X; Zhang, JH; Zhao, S, 2012) |
| "This study evaluated whether 2% hydrogen (H(2)) gas therapy protects against testicular ischemia/reperfusion injury which results in increased formation of reactive oxygen species and/or reactive nitrogen species, leading to testicular apoptosis and impaired spermatogenesis." | 7.78 | Inhaled hydrogen gas therapy for prevention of testicular ischemia/reperfusion injury in rats. ( Cho, YJ; Han, JS; Kim, JI; Lee, DH; Lee, JW; Lee, YA; Song, CS, 2012) |
| " In contrast, the upregulated level of MDA, caspase-12/3 and brain edema was attenuated and the brain injury was substantially alleviated in the hydrogen treated rabbits, but the improvement of neurology outcome was not obvious." | 7.78 | Hydrogen-rich saline alleviates early brain injury via reducing oxidative stress and brain edema following experimental subarachnoid hemorrhage in rabbits. ( Ma, CY; Shi, JX; Sun, XJ; You, WC; Zhou, ML; Zhu, L; Zhuang, Z, 2012) |
| "To study the possible anti-inflammatory effect of hydrogen-rich saline (H(2) saline) on rat hearts with regional myocardial ischemia and reperfusion (I/R)." | 7.77 | Anti-inflammatory effect of hydrogen-rich saline in a rat model of regional myocardial ischemia and reperfusion. ( He, B; Sun, Q; Sun, X; Wang, Z; Xiao, J; Zhang, Y, 2011) |
| "This study is to examine if hydrogen-rich saline reduced amyloid-beta (Aβ) induced neural inflammation and oxidative stress in a rat model by attenuation of activation of JNK and NF-κB." | 7.77 | Hydrogen-rich saline reduces oxidative stress and inflammation by inhibit of JNK and NF-κB activation in a rat model of amyloid-beta-induced Alzheimer's disease. ( Cao, YP; Li, J; Liu, Q; Sun, XJ; Wang, C; Yang, R; Zhang, JH, 2011) |
| "A ligature was placed around the maxillary molars for 4 weeks to induce periodontitis, and the animals were given drinking water with or without hydrogen-rich water." | 7.77 | Hydrogen-rich water attenuates experimental periodontitis in a rat model. ( Azuma, T; Ekuni, D; Endo, Y; Irie, K; Kasuyama, K; Morita, M; Tamaki, N; Tomofuji, T, 2011) |
| " Here, we evaluated the protective effects of hydrogen-rich saline on the l-arginine (l-Arg)-induced acute pancreatitis (AP)." | 7.76 | Hydrogen-rich saline ameliorates the severity of l-arginine-induced acute pancreatitis in rats. ( Cai, JM; Chen, H; Fan, LY; Li, Y; Liu, WW; Ruan, CP; Su, N; Sun, Q; Sun, XJ; Sun, YP; Wang, Q; Xiang, HG; Xu, XY; Yan, RL, 2010) |
| "Regional cerebral blood flow (rCBF) was studied by means of electrolytic hydrogen clearance method in chronically prepared adult cats during development of limbic seizures induced by KA microinjection into the unilateral amygdala." | 7.67 | [Regional cerebral blood flow during development of limbic seizures induced by kainic acid (KA) microinjection into unilateral amygdala in chronic cats]. ( Tanaka, S; Tanaka, T; Yonemasu, Y, 1988) |
| "Phosphate binders are most used to treat hyperphosphatemia and it is significant to develop its alternatives with high specific and low cost in the clinic." | 5.62 | Adsorptivity of cationic cellulose nanocrystals for phosphate and its application in hyperphosphatemia therapy. ( Cha, R; He, C; Liu, Q; Mu, G; Ren, H; Wang, J; Wang, M; Xie, Q; Zhang, Q, 2021) |
| "Hydrogen gas is a new medical gas that exerts anti-inflammation, antioxidation, and anti-apoptotic effects and can effectively protect septic mice." | 5.62 | Hydrogen Gas Alleviates Sepsis-Induced Brain Injury by Improving Mitochondrial Biogenesis Through the Activation of PGC-α in Mice. ( Chen, H; Mao, X; Wang, G; Wang, Y; Xie, K; Yin, L, 2021) |
| "Acute peritonitis has remained a fatal disease despite of recent advances in care and treatment, including antibiotic and anticoagulant treatments." | 5.62 | Peritoneal lavage with hydrogen-rich saline can be an effective and practical procedure for acute peritonitis. ( Egi, H; Hattori, M; Ide, K; Ohdan, H; Oue, N; Sada, H; Sawada, H; Sentani, K; Sumi, Y; Yasui, W, 2021) |
| "Hydrogen has been confirmed to have a protective role in various organs during pathological conditions and inflammation." | 5.51 | Molecular hydrogen accelerates the reversal of acute obstructive cholangitis‑induced liver dysfunction by restoring gap and tight junctions. ( Lin, W; Lu, B; Tang, H; Yu, J; Zhang, W; Zhu, Z, 2019) |
| "Hydrogen treatment downregulated the expression of necroptosis-related proteins, such as MLKL, phosphorylated-MLKL, and RIPK3 in hippocampus, and further protected neurons and astrocytes from necroptosis which was here first verified to occur in status epilepticus." | 5.51 | Hydrogen Alleviates Necroptosis and Cognitive Deficits in Lithium-Pilocarpine Model of Status Epilepticus. ( Gao, F; Jia, N; Jia, R; Jiang, W; Jiang, Y; Li, R; Liu, Z; Wang, L; Wu, S; Yang, F; Zhang, H; Zhang, S; Zhang, Z; Zhao, J, 2019) |
| "The cardiac hypertrophy was also manifested with increased expressions of atrial natriuretic peptide (ANP), brain natriuretic peptides (BNP) and fibrosis of cardiac tissues in AAC-model group, which could likewise be restrained in LHRS and HHRS groups." | 5.48 | Protective effect of hydrogen-rich saline on pressure overload-induced cardiac hypertrophyin rats: possible role of JAK-STAT signaling. ( Fan, Z; Fu, L; Gao, Y; Huang, Z; Wu, S; Xue, F; Yang, J; Zhu, L, 2018) |
| "Hydrogen has antioxidant and anti-inflammatory properties that can reduce the effects of ischemic injury." | 5.48 | Hydrogen Gas Does Not Ameliorate Renal Ischemia Reperfusion Injury in a Preclinical Model. ( Adams, T; Hosgood, SA; Moore, T; Nicholson, ML; Qurashi, M, 2018) |
| "Hydrogen treatment significantly reduced the level of oxidative stress, neuroinflammation, neuronal damage, and apoptosis-related genes." | 5.48 | Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model. ( Choi, KS; Do, SH; Hwang, SJ; Kim, HJ; Yi, HJ, 2018) |
| "Hydrogen gas has a strong prospect for clinical use due to easy preparation, low-cost, and no side effects." | 5.48 | Molecular Hydrogen Prevents Social Deficits and Depression-Like Behaviors Induced by Low-Intensity Blast in Mice. ( Araki, Y; Fujita, M; Ishizuka, T; Kashitani, M; Kobayashi, Y; Morimoto, Y; Nishii, K; Saitoh, D; Satoh, Y; Suzuki, S; Tokuno, S; Tsumatori, G; Yamamoto, T, 2018) |
| "Ischemia-reperfusion injury is one of the leading causes of tissue damage and dysfunction, in particular, free tissue transfer, traumatically amputated extremity, and prolonged tourniquet application during extremity surgery." | 5.46 | Protective Effect of Hydrogen Gas Inhalation on Muscular Damage Using a Mouse Hindlimb Ischemia-Reperfusion Injury Model. ( Iuchi, K; Kamimura, N; Nishimaki, K; Ogawa, R; Ohta, S; Watanabe, M; Yokota, T, 2017) |
| "The role of hydrogenase in carcinogenesis is demonstrated in an animal model, whereby inflammation markers and cancer development were attenuated in the hydrogenase-null strain." | 5.43 | Hydrogen Metabolism in Helicobacter pylori Plays a Role in Gastric Carcinogenesis through Facilitating CagA Translocation. ( Benoit, SL; Dominguez, RL; Maier, RJ; Morgan, DR; Peek, RM; Piazuelo, MB; Romero-Gallo, J; Wang, G, 2016) |
| "Hydrogen treatment was performed for 3 days." | 5.43 | Hydrogen does not Exert Neuroprotective Effects or Improve Functional Outcomes in Rats After Intracerebral Hemorrhage. ( Mori, K; Nagatani, K; Otani, N; Takeuchi, S; Wada, K, 2016) |
| "Spinal cord ischemia was induced by infrarenal aortic occlusion for 20min in male New Zealand white rabbits." | 5.39 | Beneficial effects of hydrogen-rich saline against spinal cord ischemia-reperfusion injury in rabbits. ( Chen, H; Gong, G; Huang, Y; Wang, X; Xie, K; Xue, W; Zeng, Y; Zhou, L, 2013) |
| "Hydrogen treatment diminished phosphorylation of Lyn kinase and release of tryptase, decreased accumulation and degranulation of mast cells, attenuated blood-brain barrier disruption, and improved neurobehavioral function." | 5.39 | Hydrogen inhalation ameliorated mast cell-mediated brain injury after intracerebral hemorrhage in mice. ( Lekic, T; Ma, Q; Manaenko, A; Tang, J; Zhang, JH, 2013) |
| "Drinking HW significantly reduced neointima formation after vein grafting in rats." | 5.38 | Oral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats. ( Bermudez, CA; Billiar, TR; Kawamura, T; Masutani, K; Nakao, A; Peng, X; Pribis, JP; Stolz, DB; Sun, Q; Sun, X; Toyoda, Y, 2012) |
| "Sepsis is associated with high morbidity and mortality, and survivors can present with cognitive dysfunction." | 5.38 | Hydrogen-rich saline reverses oxidative stress, cognitive impairment, and mortality in rats submitted to sepsis by cecal ligation and puncture. ( Bai, YP; Chen, Y; Huang, GQ; Li, J; Liu, L; Wang, J; Wu, GM; Zhou, J, 2012) |
| "Periodontitis has been causally linked to atherosclerosis, which is mediated by the oxidative stress." | 5.38 | Hydrogen-rich water prevents lipid deposition in the descending aorta in a rat periodontitis model. ( Azuma, T; Ekuni, D; Endo, Y; Irie, K; Kasuyama, K; Kojima, A; Mizutani, S; Morita, M; Tamaki, N; Tomofuji, T, 2012) |
| "Sepsis is the most common cause of death in intensive care units." | 5.38 | Combination therapy with molecular hydrogen and hyperoxia in a murine model of polymicrobial sepsis. ( Chen, H; Fu, W; Han, H; Li, A; Wang, G; Xie, K; Xing, W; Yu, Y, 2012) |
| "Transient global cerebral ischemia (TGCI) occurs during acute severe hypotension depriving the brain of oxygen and glucose for a short period of time." | 5.37 | Hydrogen supplemented air inhalation reduces changes of prooxidant enzyme and gap junction protein levels after transient global cerebral ischemia in the rat hippocampus. ( Bari, F; Domoki, F; Farkas, E; Hertelendy, P; Hugyecz, M; Mracskó, E, 2011) |
| "Hydrogen has been reported as a novel antioxidant to selectively reduce levels of toxic reactive-oxygen species (ROS)." | 5.37 | Protective effects of hydrogen-rich saline in preeclampsia rat model. ( Chen, X; Guo, L; Sun, X; Tong, X; Yang, X, 2011) |
| "Although hydrogen has been proved to be a novel therapeutic medical gas in several lung injury animal models, to our knowledge, it has not been tested yet in acute lung injury (ALI) induced by cecal ligation and puncture (CLP)." | 4.91 | Hydrogen-rich saline ameliorates lung injury associated with cecal ligation and puncture-induced sepsis in rats. ( Dai, Q; Fan, Y; Huang, X; Zhai, Y; Zhou, X, 2015) |
| "Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy." | 4.40 | Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023) |
| "The aim of this study was to investigate the efficacy and underlying mechanism of high concentration of hydrogen on lipopolysaccharide (LPS)-induced acute lung injury (ALI)." | 4.12 | High concentration of hydrogen ameliorates lipopolysaccharide-induced acute lung injury in a sirt1-dependent manner. ( Du, J; Li, J; Li, R; Yan, X, 2022) |
| "Hydrogen-rich water partially alleviates inflammation, oxidative stress and intestinal flora dysbiosis in DSS-induced chronic UC mice." | 4.12 | Hydrogen-rich water partially alleviate inflammation, oxidative stress and intestinal flora dysbiosis in DSS-induced chronic ulcerative colitis mice. ( Ding, X; Song, L; Yan, H; Yang, L; Zhang, Y; Zhu, C, 2022) |
| "Many studies have demonstrated the therapeutic effects of hydrogen in pathological conditions such as inflammation; however, little is known about its prophylactic effects." | 4.12 | Prophylactic Instillation of Hydrogen-Rich Water Decreases Corneal Inflammation and Promotes Wound Healing by Activating Antioxidant Activity in a Rat Alkali Burn Model. ( Arima, T; Ikebukuro, T; Kasamatsu, M; Nakano, Y; Shimizu, A; Takahashi, H; Tobita, Y; Uchiyama, M, 2022) |
| "This experimental study aimed to assess the efficacy of hydrogen gas inhalation against spinal cord ischemia-reperfusion injury and reveal its mechanism by measuring glutamate concentration in the ventral horn using an in vivo microdialysis method." | 4.12 | Protective effects of hydrogen gas against spinal cord ischemia-reperfusion injury. ( Fujimoto, Y; Funao, T; Kimura, A; Mori, T; Mukai, A; Suehiro, K; Yamada, T, 2022) |
| "Hydrogen treatment could potentially be a future therapeutic strategy for ischemia and its derived neurodegenerative diseases by improving cognitive abilities and inducing antioxidative and antiapoptotic effects." | 4.02 | Hydrogen-Rich Water Improves Cognitive Ability and Induces Antioxidative, Antiapoptotic, and Anti-Inflammatory Effects in an Acute Ischemia-Reperfusion Injury Mouse Model. ( Choi, JI; Lee, D, 2021) |
| "Molecular hydrogen can reduce the oxidative stress of ischemia-reperfusion injury in various organs for transplantation and potentially improve survival rates in recipients." | 3.96 | Protective effects of a hydrogen-rich solution during cold ischemia in rat lung transplantation. ( Chen-Yoshikawa, TF; Date, H; Hirano, SI; Kayawake, H; Kurokawa, R; Saito, M; Takahashi, M; Yokoyama, Y, 2020) |
| "Hydrogen provided protection from organ injury induced by sepsis via autophagy activation and endoplasmic reticulum stress pathway inactivation." | 3.96 | Hydrogen alleviated organ injury and dysfunction in sepsis: The role of cross-talk between autophagy and endoplasmic reticulum stress: Experimental research. ( Chen, HG; Han, HZ; Li, Y; Xie, KL; Yu, YH, 2020) |
| "BACKGROUND The aim of this study was to investigate the mechanisms underlying the potential effects of hydrogen-rich water (HW) on articular cartilage in a rat osteoarthritis (OA) model." | 3.96 | Protective Effects of Hydrogen-Rich Water Against Cartilage Damage in a Rat Model of Osteoarthritis by Inhibiting Oxidative Stress, Matrix Catabolism, and Apoptosis. ( Chen, W; Chen, Y; Cheng, S; Gu, Y; Peng, L; Xu, B, 2020) |
| "This study was designed to investigate the effects of low concentration hydrogen inhalation on asthma and sleep function in mice and the potential mechanism." | 3.96 | [Effects of Low Concentration Hydrogen Inhalation on Asthma and Sleep Function in Mice]. ( Du, JR; Wei, L; Zhang, XW; Zhao, Y; Zhu, L, 2020) |
| "To investigate if hydrogen-rich saline (HRS), which has been shown to have antioxidant and anti-inflammatory properties, could mitigate cardiac remodelling and reduce the incidence of atrial fibrillation (AF) in the rat model of cardiac hypertrophy." | 3.96 | Hydrogen-rich saline mitigates pressure overload-induced cardiac hypertrophy and atrial fibrillation in rats via the JAK-STAT signalling pathway. ( Pan, Z; Wang, C, 2020) |
| "Hydrogen gas (H2) inhalation during hemorrhage stabilizes post-resuscitation hemodynamics, improving short-term survival in a rat hemorrhagic shock and resuscitation (HS/R) model." | 3.96 | Hydrogen Gas Inhalation Attenuates Endothelial Glycocalyx Damage and Stabilizes Hemodynamics in a Rat Hemorrhagic Shock Model. ( Endo, J; Homma, K; Kajimura, M; Katsumata, Y; Kobayashi, E; Matsuoka, T; Sano, M; Sasaki, J; Suzuki, M; Tamura, T; Yamamoto, R; Yoshizawa, J, 2020) |
| "High concentrations of hydrogen could ameliorate pulmonary dysfunction, airway mucus hypersecretion, oxidation damage, and inflammation response in rats exposed to concentrated ambient PM2." | 3.91 | Hydrogen ameliorates lung injury in a rat model of subacute exposure to concentrated ambient PM2.5 via Aryl hydrocarbon receptor. ( Chao, L; Duan, E; Feng, S; Li, H; Li, R; Shi, X; Yan, X; Zhang, H; Zhang, W; Zhao, Y; Zhong, X, 2019) |
| "In this asphyxial CA rat model, the improved postresuscitation EEG characteristics for animals treated with hydrogen are correlated with the better 96 h neurological outcome and predicted survival." | 3.91 | Inhaling Hydrogen Ameliorates Early Postresuscitation EEG Characteristics in an Asphyxial Cardiac Arrest Rat Model. ( Chen, B; Chen, G; Li, J; Li, Y; Wang, J, 2019) |
| " Hydrogen gas provides potent anti-inflammatory and antioxidant effects against ischemia-reperfusion injury (IRI)." | 3.91 | Protective effects of hydrogen inhalation during the warm ischemia phase against lung ischemia-reperfusion injury in rat donors after cardiac death. ( Deng, L; Li, W; Liu, J; Meng, C; Zhang, J; Zhou, H, 2019) |
| "Forty-five adult male Sprague Dawley rats (body weight 220-250 g) were randomly divided into three groups: (1) Sham operation group (SH), (2) Ischemia-reperfusion injury group (IR), and (3) Ischemia-reperfusion injury with preconditioning hydrogen group (PRH)." | 3.91 | Preconditioning with one-time hydrogen gas does not attenuate skin flap ischemia-reperfusion injury in rat models. ( Dong, X; Hao, Y; Liu, H; Wang, Y, 2019) |
| " In this study, we focused on the key factors responsible for bacterial translocation including the intestinal microbiome and investigated the impact of molecular hydrogen therapy as a countermeasure against bacterial translocation in a murine model of sepsis." | 3.88 | Hydrogen-Rich Saline Regulates Intestinal Barrier Dysfunction, Dysbiosis, and Bacterial Translocation in a Murine Model of Sepsis. ( Hirano, SI; Ichimaru, N; Ikeda, M; Kurakawa, T; Motooka, D; Nakamura, S; Ogura, H; Shimazu, T; Shimizu, K; Takahara, S; Takeda, K; Umemoto, E, 2018) |
| " This study aims to investigate the potential effects of hydrogen-rich saline (HRS) administration on naloxone-precipitated withdrawal symptoms and morphine withdrawal-induced anxiety-like behaviors." | 3.85 | Hydrogen-rich saline attenuates anxiety-like behaviors in morphine-withdrawn mice. ( Cong, B; Gong, M; Guo, H; Hui, R; Ma, C; Shen, Q; Wang, J; Wen, D; Zhao, P, 2017) |
| "Inhaled hydrogen gas (H2) provides protection in rat models of human acute lung injury (ALI)." | 3.85 | Protection by Inhaled Hydrogen Therapy in a Rat Model of Acute Lung Injury can be Tracked in vivo Using Molecular Imaging. ( Audi, SH; Camara, AKS; Clough, AV; Jacobs, ER; Medhora, MM; Rizzo, B; Zhang, X; Zhao, M, 2017) |
| "It is not known whether simultaneous delivery of hydrogen and oxygen can reduce injury caused by hemorrhagic shock and resuscitation (HSR)." | 3.85 | Hyperoxygenated hydrogen-rich solution suppresses shock- and resuscitation-induced liver injury. ( Dang, Y; Deng, B; Gou, X; Liu, T; Mei, X; Meng, X; Xu, H; Xu, L, 2017) |
| "By using an L-arginine induced chronic pancreatitis mouse model, we tested the therapeutic potential of hydrogen, a strong hydroxyl radicals scavenger, in the chronic pancreatitis model." | 3.85 | Hydrogen Treatment Protects Mice Against Chronic Pancreatitis by Restoring Regulatory T Cells Loss. ( Bian, Y; Chen, L; Li, J; Lu, J; Ma, C; Su, L; Wang, T, 2017) |
| "The objective of this study was to investigate the protective effects of molecular hydrogen, a novel and selective antioxidant, on steroid-induced osteonecrosis (ON) in a rabbit model." | 3.85 | Protective effects of molecular hydrogen on steroid-induced osteonecrosis in rabbits via reducing oxidative stress and apoptosis. ( Fan, L; Ge, Z; Li, J; Wang, K, 2017) |
| "To investigate the role of Rho/ROCK signaling pathway in the protective effects of hydrogen gas (H2) on acute lung injury (ALI) in a mouse model of sepsis." | 3.83 | [Role of Rho/ROCK signaling pathway in the protective effects of hydrogen against acute lung injury in septic mice]. ( Liang, Y; Liu, L; Sun, Z; Yu, Y; Zhang, H, 2016) |
| "A single intraperitoneal dose of hydrogen-rich saline ameliorates postoperative ileus by inhibiting the inflammatory response and suppressing nitric oxide production." | 3.83 | Intraperitoneally administered, hydrogen-rich physiologic solution protects against postoperative ileus and is associated with reduced nitric oxide production. ( Aoyama-Ishikawa, M; Fujisaki, N; Iida, A; Kohama, K; Kotani, J; Naito, H; Nakao, A; Nosaka, N; Okamoto, A; Sato, K; Tsukahara, K; Yamada, T; Yamashita, H; Yumoto, T, 2016) |
| " Therefore because oxidative stress plays a significant role in the pathophysiology of myocardial infarction (MI), the aim of our study was to investigate whether hydrogen-rich saline has cardioprotective effects against isoproterenol-induced MI in rats." | 3.81 | Cardioprotective Effect of Hydrogen-rich Saline on Isoproterenol-induced Myocardial Infarction in Rats. ( Han, JJ; Jing, L; Qin, SC; Sun, XJ; Wang, Y; Zhao, B; Zhao, XM, 2015) |
| "Hydrogen (H(2)) attenuates the development of atherosclerosis in mouse models." | 3.81 | Molecular hydrogen stabilizes atherosclerotic plaque in low-density lipoprotein receptor-knockout mice. ( Jiao, P; Qin, S; Song, G; Sun, X; Tian, H; Tian, S; Wu, Y; Yao, S; Yu, Y; Zhai, L; Zhang, X; Zhang, Z; Zhao, H; Zong, C, 2015) |
| "To investigate the effects of hydrogen-rich saline on cardiomyocyte autophagy during myocardial ischemia-reperfusion in aged rats." | 3.81 | [Effect of hydrogen-rich saline on cardiomyocyte autophagy during myocardial ischemia-reperfusion in aged rats]. ( Liu, D; Pan, Z; Xu, H; Yu, H; Zhao, Y, 2015) |
| "Pretreatment by HRS ameliorated renal dysfunction in glycerol-induced rhabdomyolysis by inhibiting oxidative stress and the inflammatory response." | 3.80 | Pretreatment with hydrogen-rich saline reduces the damage caused by glycerol-induced rhabdomyolysis and acute kidney injury in rats. ( Gao, X; Gu, H; Sun, X; Yang, M; Zhao, B; Zhao, X, 2014) |
| "To explore the mechanism of hydrogen on the intervention of abdominal aortic aneurysm (AAA)." | 3.80 | [Suppression of abdominal aortic aneurysm by hydrogen through chemokine-like factor1]. ( Chen, F; Guo, W; Jia, S; Liu, J; Pan, X; Shen, C; Song, Y; Xiong, J; Zhang, T, 2014) |
| "To study the effect of hydrogen-rich water (HRW) on acute peritonitis with three different rat models." | 3.80 | Effect of hydrogen-rich water on acute peritonitis of rat models. ( Liu, C; Song, S; Tai, M; Wan, Y; Wu, Q; Zhang, J; Zhang, R, 2014) |
| "To investigate the role of Nrf2 on hydrogen treatment for intestinal injury caused by severe sepsis." | 3.80 | [The role of Nrf2 in the hydrogen treatment for intestinal injury caused by severe sepsis]. ( Chen, H; Li, Y; Wang, G; Wang, W; Xie, K; Yu, Y, 2014) |
| "To investigate the role of nuclear factor erythroid 2-related factor 2 (Nrf2) in the protective effects of hydrogen against cerebral dysfunction in a mouse model of sepsis." | 3.80 | [Role of Nrf2 in the protective effects of hydrogen against cerebral dysfunction in septic mice]. ( Chen, H; Dong, X; Liu, L; Wang, G; Xie, K; Yu, Y, 2014) |
| "These results suggest that hydrogen has a positive effect on acute radiodermatitis." | 3.80 | Hydrogen protects rats from dermatitis caused by local radiation. ( Cai, J; Li, B; Mei, K; Ni, J; Qian, L; Zhao, S, 2014) |
| "Asthma was induced by ovalbumin (OVA) sensitization and challenge." | 3.79 | Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma. ( Wang, T; Wen, FQ; Xiao, M; Zhu, T, 2013) |
| "To investigate the effect of hydrogen inhalation on acute lung injury after hemorrhagic shock in rats." | 3.79 | [The effect of hydrogen on hemorrhagic shock induced acute lung injury in rats]. ( Jia, YR; Liu, JF; Shi, HM; Wang, Y; Zhou, HC, 2013) |
| "The administration of acetic acid induced acute rat UC, as indicated by diarrhea, weight loss, and colonic mucosal damage." | 3.79 | Protective effects of hydrogen-rich saline on ulcerative colitis rat model. ( He, J; Mei, X; Sun, A; Sun, X; Wang, J; Wang, Q; Xiong, S; Zhang, C; Zhang, J, 2013) |
| "To investigate the effects of saturated hydrogen saline on the prevention of abdominal aortic aneurysm (AAA) induced by calcium chloride in a rat model." | 3.79 | [Suppression of experimental abdominal aortic aneurysm by saturated hydrogen saline: a preliminary study with rats]. ( Chen, F; Guo, W; Jia, SH; Liu, J; Pan, XJ; Song, YX; Xiong, J; Zhang, T, 2013) |
| "To determine the effect of saturated hydrogen saline on lipopolysaccharide (LPS)-induced acute liver dysfunction, rats were divided into control, LPS, and LPS plus saturated hydrogen saline (LPS+H(2)) groups." | 3.79 | Saturated hydrogen saline attenuates endotoxin-induced acute liver dysfunction in rats. ( Xu, XF; Zhang, J, 2013) |
| "By observation of the diameter, progression rate, wall thickness, and the opening angle of the abnormal aortic of abdominal aortic aneurysm (AAA) in rats, to observe the effect of saturated hydrogen saline on residual strain of AAA rats, and to investigate its inhibition effect on AAA formation." | 3.79 | [A study on residual strain of abdominal aortic aneurysm after intraperitoneal administration of saturated hydrogen saline in rats]. ( Chen, F; Guo, W; Jia, S; Liu, J; Pan, X; Song, Y; Xiong, J, 2013) |
| "Hydrogen-rich saline effectively improved erectile function in a streptozotocin induced diabetic rat model of erectile dysfunction." | 3.79 | Protective effects of hydrogen-rich saline against erectile dysfunction in a streptozotocin induced diabetic rat model. ( Chao, Z; Chen, L; Fan, M; He, X; Liu, J; Qian, L; Qing, J; Sun, X; Xu, X, 2013) |
| "Hydrogen saline may be a potential treatment for hyperoxia-induced retinopathy that acts via the inhibition of oxidative stress and the reduction of VEGF expression." | 3.78 | Hydrogen saline treatment attenuates hyperoxia-induced retinopathy by inhibition of oxidative stress and reduction of VEGF expression. ( Huang, L; Sun, X; Zhang, JH; Zhao, S, 2012) |
| "These results reveal that administration of hydrogen-saturated saline decreases athero-susceptibility in apoB-containing lipoprotein and aortic atherosclerosis in apoE-/- mice and improves HDL functionality in C57BL/6J mice." | 3.78 | Hydrogen decreases athero-susceptibility in apolipoprotein B-containing lipoproteins and aorta of apolipoprotein E knockout mice. ( Liu, J; Luo, Y; Qin, S; Sang, H; Song, G; Sun, X; Tian, H; Wang, X; Yao, S; Yu, Y; Zong, C, 2012) |
| "This study evaluated whether 2% hydrogen (H(2)) gas therapy protects against testicular ischemia/reperfusion injury which results in increased formation of reactive oxygen species and/or reactive nitrogen species, leading to testicular apoptosis and impaired spermatogenesis." | 3.78 | Inhaled hydrogen gas therapy for prevention of testicular ischemia/reperfusion injury in rats. ( Cho, YJ; Han, JS; Kim, JI; Lee, DH; Lee, JW; Lee, YA; Song, CS, 2012) |
| " In contrast, the upregulated level of MDA, caspase-12/3 and brain edema was attenuated and the brain injury was substantially alleviated in the hydrogen treated rabbits, but the improvement of neurology outcome was not obvious." | 3.78 | Hydrogen-rich saline alleviates early brain injury via reducing oxidative stress and brain edema following experimental subarachnoid hemorrhage in rabbits. ( Ma, CY; Shi, JX; Sun, XJ; You, WC; Zhou, ML; Zhu, L; Zhuang, Z, 2012) |
| "To study the possible anti-inflammatory effect of hydrogen-rich saline (H(2) saline) on rat hearts with regional myocardial ischemia and reperfusion (I/R)." | 3.77 | Anti-inflammatory effect of hydrogen-rich saline in a rat model of regional myocardial ischemia and reperfusion. ( He, B; Sun, Q; Sun, X; Wang, Z; Xiao, J; Zhang, Y, 2011) |
| "This study is to examine if hydrogen-rich saline reduced amyloid-beta (Aβ) induced neural inflammation and oxidative stress in a rat model by attenuation of activation of JNK and NF-κB." | 3.77 | Hydrogen-rich saline reduces oxidative stress and inflammation by inhibit of JNK and NF-κB activation in a rat model of amyloid-beta-induced Alzheimer's disease. ( Cao, YP; Li, J; Liu, Q; Sun, XJ; Wang, C; Yang, R; Zhang, JH, 2011) |
| "A ligature was placed around the maxillary molars for 4 weeks to induce periodontitis, and the animals were given drinking water with or without hydrogen-rich water." | 3.77 | Hydrogen-rich water attenuates experimental periodontitis in a rat model. ( Azuma, T; Ekuni, D; Endo, Y; Irie, K; Kasuyama, K; Morita, M; Tamaki, N; Tomofuji, T, 2011) |
| " Here, we evaluated the protective effects of hydrogen-rich saline on the l-arginine (l-Arg)-induced acute pancreatitis (AP)." | 3.76 | Hydrogen-rich saline ameliorates the severity of l-arginine-induced acute pancreatitis in rats. ( Cai, JM; Chen, H; Fan, LY; Li, Y; Liu, WW; Ruan, CP; Su, N; Sun, Q; Sun, XJ; Sun, YP; Wang, Q; Xiang, HG; Xu, XY; Yan, RL, 2010) |
| " Hydrogen gas treatment increased the 7-d survival rate of severe CLP mice to 60 % (Compared with severe sepsis group, P <0." | 3.76 | [Effects of hydrogen gas inhalation on serum high mobility group box 1 levels in severe septic mice]. ( Hou, LC; Wang, GL; Xie, KL; Xiong, LZ, 2010) |
| "The inhibition of Na(+)-H+ exchange (NHE) with amiloride analogues in vitro has been shown to prevent reperfusion arrhythmias and additional cell necrosis." | 3.69 | Role of Na(+)-H+ exchange on reperfusion related myocardial injury and arrhythmias in an open-chest swine model. ( Fukuta, M; Iwa, T; Kobayashi, T; Uesugi, M; Wakida, Y, 1996) |
| "Regional cerebral blood flow (rCBF) was studied by means of electrolytic hydrogen clearance method in chronically prepared adult cats during development of limbic seizures induced by KA microinjection into the unilateral amygdala." | 3.67 | [Regional cerebral blood flow during development of limbic seizures induced by kainic acid (KA) microinjection into unilateral amygdala in chronic cats]. ( Tanaka, S; Tanaka, T; Yonemasu, Y, 1988) |
| "Hydrogen gas has been reported to have medical efficacy since the 1880s." | 2.61 | Medical Application of Hydrogen in Hematological Diseases. ( Cen, J; Pasca, S; Qian, L; Tomuleasa, C; Wu, Z, 2019) |
| " First, no dose-response effect is observed." | 2.48 | Molecular hydrogen as an emerging therapeutic medical gas for neurodegenerative and other diseases. ( Ichihara, M; Ito, M; Ohno, K, 2012) |
| "Human hepatic encephalopathy (HE) is identified by a new noninvasive test, proton magnetic resonance spectroscopy (1H MRS) applied to the brain in a few minutes." | 2.39 | Proton magnetic resonance spectroscopy: the new gold standard for diagnosis of clinical and subclinical hepatic encephalopathy? ( Blüml, S; Danielsen, ER; Ross, BD, 1996) |
| "Phosphate binders are most used to treat hyperphosphatemia and it is significant to develop its alternatives with high specific and low cost in the clinic." | 1.62 | Adsorptivity of cationic cellulose nanocrystals for phosphate and its application in hyperphosphatemia therapy. ( Cha, R; He, C; Liu, Q; Mu, G; Ren, H; Wang, J; Wang, M; Xie, Q; Zhang, Q, 2021) |
| "Hydrogen gas is a new medical gas that exerts anti-inflammation, antioxidation, and anti-apoptotic effects and can effectively protect septic mice." | 1.62 | Hydrogen Gas Alleviates Sepsis-Induced Brain Injury by Improving Mitochondrial Biogenesis Through the Activation of PGC-α in Mice. ( Chen, H; Mao, X; Wang, G; Wang, Y; Xie, K; Yin, L, 2021) |
| "Hydrogen inhalation has recently been shown to be an effective treatment for inflammatory lung injury, but the underlying mechanism is unknown." | 1.62 | Hydrogen Attenuates Endotoxin-Induced Lung Injury by Activating Thioredoxin 1 and Decreasing Tissue Factor Expression. ( Cheng, H; Duan, M; Hu, F; Hu, L; Jiang, L; Li, J; Li, Q; Liu, WT; Long, Y; Shi, Y; Wan, B; Xu, M; Yu, P; Yu, W, 2021) |
| "Acute peritonitis has remained a fatal disease despite of recent advances in care and treatment, including antibiotic and anticoagulant treatments." | 1.62 | Peritoneal lavage with hydrogen-rich saline can be an effective and practical procedure for acute peritonitis. ( Egi, H; Hattori, M; Ide, K; Ohdan, H; Oue, N; Sada, H; Sawada, H; Sentani, K; Sumi, Y; Yasui, W, 2021) |
| "Hydrogen pretreatment upregulated ROS and the expression of pyroptosis-related proteins, and increased the number of PI- and TUNEL-positive cells, as well as the release of LDH and IL-1β, however, GSDMD depletion reduced their release." | 1.56 | Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway. ( Bao, W; Chen, SJ; Liu, PY; Wu, FS; Yang, Y; Zhu, PY, 2020) |
| "Rheumatoid arthritis (RA)-associated interstitial lung disease (ILD), a primary cause of mortality in patients with RA, has limited treatment options." | 1.51 | Effect of H ( Akimoto, T; Igarashi, T; Kajimoto, Y; Kanazawa, S; Kokuho, N; Kunugi, S; Maruyama, M; Miura, Y; Ohsawa, I; Shimizu, A; Terasaki, M; Terasaki, Y; Urushiyama, H, 2019) |
| "Hydrogen‑rich saline was administered twice through intraperitoneal injection at a daily dose of 10 ml/kg following the operation in the in vivo model, and hydrogen‑rich medium culture was used for cells instead of normal medium in vitro." | 1.51 | Hydrogen-rich saline alleviates inflammation and apoptosis in myocardial I/R injury via PINK-mediated autophagy. ( Chen, H; Wu, Q; Xie, K; Yao, L, 2019) |
| "When hydrogen gas was infused into a bag containing cold ETK organ preservation solution at a pressure of 0." | 1.51 | Organ preservation solution containing dissolved hydrogen gas from a hydrogen-absorbing alloy canister improves function of transplanted ischemic kidneys in miniature pigs. ( Kobayashi, E; Sano, M, 2019) |
| "Hydrogen has been shown to exert a bioactive effect on the myocardium." | 1.51 | Attenuation of Cardiac Ischaemia-reperfusion Injury by Treatment with Hydrogen-rich Water. ( Geng, YJ; Li, L; Li, X; Li, Z; Liu, F; Liu, X; Sun, X; Wu, J; Zhou, Y, 2019) |
| "Hydrogen has been confirmed to have a protective role in various organs during pathological conditions and inflammation." | 1.51 | Molecular hydrogen accelerates the reversal of acute obstructive cholangitis‑induced liver dysfunction by restoring gap and tight junctions. ( Lin, W; Lu, B; Tang, H; Yu, J; Zhang, W; Zhu, Z, 2019) |
| "Hydrogen treatment downregulated the expression of necroptosis-related proteins, such as MLKL, phosphorylated-MLKL, and RIPK3 in hippocampus, and further protected neurons and astrocytes from necroptosis which was here first verified to occur in status epilepticus." | 1.51 | Hydrogen Alleviates Necroptosis and Cognitive Deficits in Lithium-Pilocarpine Model of Status Epilepticus. ( Gao, F; Jia, N; Jia, R; Jiang, W; Jiang, Y; Li, R; Liu, Z; Wang, L; Wu, S; Yang, F; Zhang, H; Zhang, S; Zhang, Z; Zhao, J, 2019) |
| "Hydrogen inhaling was superior to mild hypothermia for improving neurological outcome and survival in cardiac arrest and resuscitation model of systemic hypertension rats." | 1.48 | Hydrogen Inhalation is Superior to Mild Hypothermia for Improving Neurological Outcome and Survival in a Cardiac Arrest Model of Spontaneously Hypertensive Rat. ( Chen, B; Chen, G; Dai, C; Huang, Y; Li, Y; Wang, J, 2018) |
| "The cardiac hypertrophy was also manifested with increased expressions of atrial natriuretic peptide (ANP), brain natriuretic peptides (BNP) and fibrosis of cardiac tissues in AAC-model group, which could likewise be restrained in LHRS and HHRS groups." | 1.48 | Protective effect of hydrogen-rich saline on pressure overload-induced cardiac hypertrophyin rats: possible role of JAK-STAT signaling. ( Fan, Z; Fu, L; Gao, Y; Huang, Z; Wu, S; Xue, F; Yang, J; Zhu, L, 2018) |
| "Hydrogen has antioxidant and anti-inflammatory properties that can reduce the effects of ischemic injury." | 1.48 | Hydrogen Gas Does Not Ameliorate Renal Ischemia Reperfusion Injury in a Preclinical Model. ( Adams, T; Hosgood, SA; Moore, T; Nicholson, ML; Qurashi, M, 2018) |
| "Neuropathic pain is a chronic and intractable pain, with very few effective analgesics." | 1.48 | Hydrogen-Rich Saline Activated Autophagy via HIF-1 ( Chen, H; Huo, X; Li, B; Liu, J; Ma, W; Shi, K; Wang, H; Wang, X; Xie, K; Yu, Y, 2018) |
| "Hydrogen-rich water was recently shown to exert neuroprotective effects in various neurological diseases through its antioxidant properties." | 1.48 | Hydrogen-rich water attenuates oxidative stress in rats with traumatic brain injury via Nrf2 pathway. ( Chen, X; Fu, J; Liu, X; Liu, Y; Shen, F; Wang, D; Yuan, J; Zhang, H, 2018) |
| "Hydrogen treatment significantly reduced the level of oxidative stress, neuroinflammation, neuronal damage, and apoptosis-related genes." | 1.48 | Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model. ( Choi, KS; Do, SH; Hwang, SJ; Kim, HJ; Yi, HJ, 2018) |
| "Hydrogen gas has a strong prospect for clinical use due to easy preparation, low-cost, and no side effects." | 1.48 | Molecular Hydrogen Prevents Social Deficits and Depression-Like Behaviors Induced by Low-Intensity Blast in Mice. ( Araki, Y; Fujita, M; Ishizuka, T; Kashitani, M; Kobayashi, Y; Morimoto, Y; Nishii, K; Saitoh, D; Satoh, Y; Suzuki, S; Tokuno, S; Tsumatori, G; Yamamoto, T, 2018) |
| "Chronic obstructive pulmonary disease (COPD) is a progressive pulmonary disease caused by harmful gases or particles." | 1.46 | Hydrogen coadministration slows the development of COPD-like lung disease in a cigarette smoke-induced rat model. ( Li, Z; Liu, X; Ma, C; Sun, W; Wang, P; Wang, W; Wang, X; Xue, B, 2017) |
| "Mortality of hemorrhagic shock primarily depends on whether or not the patients can endure the loss of circulating volume until radical treatment is applied." | 1.46 | Hydrogen gas inhalation inhibits progression to the "irreversible" stage of shock after severe hemorrhage in rats. ( Fukuda, K; Hayashida, K; Homma, K; Matsuoka, T; Sano, M; Sasaki, J; Suzuki, M; Tamura, T, 2017) |
| "Sprague-Dawley rats were made chronic obstructive pulmonary disease models via tobacco smoke exposure for 12 weeks and the rats were treated with 10 ml/kg hydrogen-rich saline intraperitoneally during the last 4 weeks." | 1.46 | Hydrogen-rich saline inhibits tobacco smoke-induced chronic obstructive pulmonary disease by alleviating airway inflammation and mucus hypersecretion in rats. ( Geng, W; Jiang, C; Li, C; Liu, Y; Liu, Z; Qin, S; Si, Y; Zhang, X; Zhang, Y; Zhao, S, 2017) |
| "Ischemia-reperfusion injury is one of the leading causes of tissue damage and dysfunction, in particular, free tissue transfer, traumatically amputated extremity, and prolonged tourniquet application during extremity surgery." | 1.46 | Protective Effect of Hydrogen Gas Inhalation on Muscular Damage Using a Mouse Hindlimb Ischemia-Reperfusion Injury Model. ( Iuchi, K; Kamimura, N; Nishimaki, K; Ogawa, R; Ohta, S; Watanabe, M; Yokota, T, 2017) |
| "The role of hydrogenase in carcinogenesis is demonstrated in an animal model, whereby inflammation markers and cancer development were attenuated in the hydrogenase-null strain." | 1.43 | Hydrogen Metabolism in Helicobacter pylori Plays a Role in Gastric Carcinogenesis through Facilitating CagA Translocation. ( Benoit, SL; Dominguez, RL; Maier, RJ; Morgan, DR; Peek, RM; Piazuelo, MB; Romero-Gallo, J; Wang, G, 2016) |
| "Hydrogen treatment was performed for 3 days." | 1.43 | Hydrogen does not Exert Neuroprotective Effects or Improve Functional Outcomes in Rats After Intracerebral Hemorrhage. ( Mori, K; Nagatani, K; Otani, N; Takeuchi, S; Wada, K, 2016) |
| "Hydrogen (H2) has anti-inflammation, anti-apoptosis, and anti-oxidative stress effects." | 1.42 | H2 Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain. ( Chen, H; Chen, Y; Li, Y; Liu, L; Wang, G; Xie, K; Yu, Y, 2015) |
| "The rat model of ulcerative colitis was used to evaluate the efficiency of our loaded pellets as a drug carrier." | 1.40 | Preparation and evaluation of colon adhesive pellets of 5-aminosalicylic acid. ( Elamin, ES; Ping, Q; Qiao, H; Sun, M; Xu, M, 2014) |
| "Hydrogen-rich saline treatment dose dependently improved survival and neurological function after cardiac arrest/resuscitation." | 1.40 | Hydrogen-rich saline improves survival and neurological outcome after cardiac arrest and cardiopulmonary resuscitation in rats. ( Chen, HG; Dong, HL; Han, HZ; Huang, Y; Huo, TT; Liu, XN; Lu, ZH; Nie, H; Sun, L; Xie, KL; Xiong, LZ; Zeng, Y, 2014) |
| "Five minutes after achieving ROSC, post-cardiac arrest rats were randomized into 4 groups: mechanically ventilated with 26% O2 and normothermia (control); mechanically ventilated with 26% O2, 1." | 1.40 | Hydrogen inhalation during normoxic resuscitation improves neurological outcome in a rat model of cardiac arrest independently of targeted temperature management. ( Fukuda, K; Hayashida, K; Hori, S; Kamimura, N; Ohta, S; Sano, M; Suzuki, M; Yokota, T, 2014) |
| "The hydrogen gas treatment had no significant effect on vital signs or CBF values." | 1.39 | The effect of hydrogen gas on a mouse bilateral common carotid artery occlusion. ( Fujita, M; Kobayashi, H; Nagatani, K; Nawashiro, H; Otani, N; Shima, K; Tachibana, S; Takeuchi, S; Wada, K, 2013) |
| "Spinal cord ischemia was induced by infrarenal aortic occlusion for 20min in male New Zealand white rabbits." | 1.39 | Beneficial effects of hydrogen-rich saline against spinal cord ischemia-reperfusion injury in rabbits. ( Chen, H; Gong, G; Huang, Y; Wang, X; Xie, K; Xue, W; Zeng, Y; Zhou, L, 2013) |
| "Hydrogen-rich solution was reported to inhibit the levels of cytokines including INF-γ, TNF-α and IL-6 in vivo in recent studies." | 1.39 | Therapeutic effects of hydrogen-rich solution on aplastic anemia in vivo. ( Cai, J; Gao, F; Huang, Y; Li, B; Liu, C; Liu, W; Mei, K; Ni, J; Qian, L; Sun, X; Yang, Y; Zhang, C; Zhao, S, 2013) |
| "Hydrogen (H(2)) acts as a therapeutic antioxidant." | 1.39 | Hydrogen improves glycemic control in type1 diabetic animal model by promoting glucose uptake into skeletal muscle. ( Amitani, H; Amitani, M; Asakawa, A; Chaolu, H; Cheng, K; Inui, A; Kaimoto, K; Kamimura, R; Li, JB; Li, Y; Nakano, M; Terashi, M; Tsai, M; Ushikai, M, 2013) |
| "Hydrogen treatment diminished phosphorylation of Lyn kinase and release of tryptase, decreased accumulation and degranulation of mast cells, attenuated blood-brain barrier disruption, and improved neurobehavioral function." | 1.39 | Hydrogen inhalation ameliorated mast cell-mediated brain injury after intracerebral hemorrhage in mice. ( Lekic, T; Ma, Q; Manaenko, A; Tang, J; Zhang, JH, 2013) |
| "Drinking HW significantly reduced neointima formation after vein grafting in rats." | 1.38 | Oral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats. ( Bermudez, CA; Billiar, TR; Kawamura, T; Masutani, K; Nakao, A; Peng, X; Pribis, JP; Stolz, DB; Sun, Q; Sun, X; Toyoda, Y, 2012) |
| "Hydrogen-rich saline was administered twice daily for 6 days (2." | 1.38 | Hydrogen-rich saline alleviates experimental noise-induced hearing loss in guinea pigs. ( Chen, X; Kang, M; Ruan, F; Sun, X; Zhang, Q; Zheng, G; Zheng, H; Zhou, Y, 2012) |
| "Hydrogen gas (H(2)) has been considered as a novel antioxidant to selectively reduce the toxic reactive oxygen species (ROS) such as hydroxyl radical (•OH) without affecting the other signal ROS." | 1.38 | Protective effects of hydrogen-rich saline in a rat model of traumatic brain injury via reducing oxidative stress. ( Fei, Z; Ji, X; Liu, W; Qu, Y; Tian, Y; Xie, K, 2012) |
| "Sepsis is associated with high morbidity and mortality, and survivors can present with cognitive dysfunction." | 1.38 | Hydrogen-rich saline reverses oxidative stress, cognitive impairment, and mortality in rats submitted to sepsis by cecal ligation and puncture. ( Bai, YP; Chen, Y; Huang, GQ; Li, J; Liu, L; Wang, J; Wu, GM; Zhou, J, 2012) |
| "Periodontitis has been causally linked to atherosclerosis, which is mediated by the oxidative stress." | 1.38 | Hydrogen-rich water prevents lipid deposition in the descending aorta in a rat periodontitis model. ( Azuma, T; Ekuni, D; Endo, Y; Irie, K; Kasuyama, K; Kojima, A; Mizutani, S; Morita, M; Tamaki, N; Tomofuji, T, 2012) |
| "Sepsis is the most common cause of death in intensive care units." | 1.38 | Combination therapy with molecular hydrogen and hyperoxia in a murine model of polymicrobial sepsis. ( Chen, H; Fu, W; Han, H; Li, A; Wang, G; Xie, K; Xing, W; Yu, Y, 2012) |
| "Transient global cerebral ischemia (TGCI) occurs during acute severe hypotension depriving the brain of oxygen and glucose for a short period of time." | 1.37 | Hydrogen supplemented air inhalation reduces changes of prooxidant enzyme and gap junction protein levels after transient global cerebral ischemia in the rat hippocampus. ( Bari, F; Domoki, F; Farkas, E; Hertelendy, P; Hugyecz, M; Mracskó, E, 2011) |
| "Hydrogen (H2) is a potent antioxidant shown to selectively reverse cytotoxic oxygen-radical injury in the brain." | 1.37 | Protective effect of hydrogen gas therapy after germinal matrix hemorrhage in neonatal rats. ( Fathali, N; Lekic, T; Manaenko, A; Peterson, M; Rolland, W; Tang, J; Zhang, JH, 2011) |
| "Hydrogen has been reported as a novel antioxidant to selectively reduce levels of toxic reactive-oxygen species (ROS)." | 1.37 | Protective effects of hydrogen-rich saline in preeclampsia rat model. ( Chen, X; Guo, L; Sun, X; Tong, X; Yang, X, 2011) |
| "Hydrogen-rich saline treatment improved Morris Water Maze and enhanced LTP in hippocampus blocked by Abeta1-42." | 1.36 | Hydrogen-rich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer's disease by reduction of oxidative stress. ( Cai, JM; Cao, YP; Li, J; Sun, XJ; Wang, C; Zhang, JH, 2010) |
| "Hydrogen (H2) has been reported to neutralize toxic reactive oxygen species." | 1.36 | Hydrogen is neuroprotective and preserves cerebrovascular reactivity in asphyxiated newborn pigs. ( Bari, F; Domoki, F; Hugyecz, M; Németh, I; Oláh, O; Temesvári, P; Tóth-Szuki, V; Zimmermann, A, 2010) |
| "The hydrogen-rich saline was prepared (hydrogen-saturated normal saline with hydrogen concentration of 0." | 1.36 | [Effect of hydrogen-rich saline on blood pressure and antioxidant ability of lung tissue in scalded rats following delayed resuscitation]. ( Chen, B; Fu, JF; Jin, YC; Luo, PF; Qiu, XC; Sun, Y; Xia, ZF, 2010) |
| "Hydrogen gas (H(2)) has been shown to ameliorate brain injury in experimental adult rat focal ischemia and in a mild neonatal hypoxia-ischemia (HI, 90 min hypoxia) rat model." | 1.35 | Hydrogen gas is ineffective in moderate and severe neonatal hypoxia-ischemia rat models. ( Dorotta, IR; Fathali, N; Hasegawa, Y; Jadhav, V; Martin, RD; Matchett, GA; Ostrowski, RP; Sun, X; Zhang, JH, 2009) |
| " Here, we show that drinking H(2)-containing water significantly reduced the loss of dopaminergic neurons in PD model mice using both acute and chronic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)." | 1.35 | Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. ( Fujita, K; Katafuchi, T; Kido, MA; Nakabeppu, Y; Noda, M; Ohno, M; Sakumi, K; Seike, T; Takaki, A; Tanaka, Y; Yamada, H; Yamaguchi, H; Yamakawa, Y; Yutsudo, N, 2009) |
| "Enalapril treatment significantly improved water maze performance (P<0." | 1.32 | Angiotensin converting enzyme inhibition partially prevents deficits in water maze performance, hippocampal synaptic plasticity and cerebral blood flow in streptozotocin-diabetic rats. ( Biessels, GJ; Cameron, NE; Cotter, MA; Gispen, WH; Kamal, A; Kappelle, LJ; Manschot, SM, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (2.15) | 18.7374 |
| 1990's | 4 (1.72) | 18.2507 |
| 2000's | 21 (9.01) | 29.6817 |
| 2010's | 156 (66.95) | 24.3611 |
| 2020's | 47 (20.17) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, Q | 7 |
| Wang, M | 2 |
| Mu, G | 1 |
| Ren, H | 2 |
| He, C | 3 |
| Xie, Q | 1 |
| Liu, Q | 8 |
| Wang, J | 16 |
| Cha, R | 1 |
| Xu, M | 2 |
| Sun, M | 2 |
| Qiao, H | 1 |
| Ping, Q | 1 |
| Elamin, ES | 1 |
| Mostafa, DM | 1 |
| Ammar, NM | 1 |
| Abd El-Alim, SH | 1 |
| Kassem, AA | 1 |
| Hussein, RA | 1 |
| Awad, G | 1 |
| El-Awdan, SA | 1 |
| Miura, M | 1 |
| Imai, K | 2 |
| Tsuda, H | 2 |
| Miki, R | 2 |
| Tano, S | 1 |
| Ito, Y | 2 |
| Hirako-Takamura, S | 1 |
| Moriyama, Y | 1 |
| Ushida, T | 2 |
| Iitani, Y | 1 |
| Nakano-Kobayashi, T | 1 |
| Toyokuni, S | 2 |
| Kajiyama, H | 2 |
| Kotani, T | 2 |
| Qian, L | 6 |
| Liu, J | 14 |
| Ma, W | 2 |
| Liu, Y | 10 |
| Wang, X | 14 |
| Liu, D | 3 |
| Lee, D | 1 |
| Choi, JI | 1 |
| Du, J | 1 |
| Li, J | 18 |
| Li, R | 6 |
| Yan, X | 3 |
| Liang, IC | 1 |
| Ko, WC | 1 |
| Hsu, YJ | 1 |
| Lin, YR | 1 |
| Chang, YH | 1 |
| Zong, XH | 1 |
| Lai, PC | 1 |
| Chang, DC | 1 |
| Hung, CF | 1 |
| Song, L | 1 |
| Zhang, Y | 13 |
| Zhu, C | 1 |
| Ding, X | 1 |
| Yang, L | 1 |
| Yan, H | 1 |
| An, P | 1 |
| Zhao, XC | 1 |
| Liu, MJ | 1 |
| You, YQ | 1 |
| Li, JY | 1 |
| Otani, N | 3 |
| Tomita, K | 1 |
| Kobayashi, Y | 5 |
| Kuroda, K | 1 |
| Koyama, Y | 3 |
| Kobayashi, H | 6 |
| Kubo, T | 1 |
| Hirota, I | 1 |
| Sun, Y | 8 |
| Ohtsu, I | 1 |
| Imai, H | 1 |
| Yoshioka, Y | 1 |
| Yanagawa, H | 1 |
| Sumi, T | 1 |
| Shimada, S | 2 |
| Kasamatsu, M | 1 |
| Arima, T | 1 |
| Ikebukuro, T | 1 |
| Nakano, Y | 1 |
| Tobita, Y | 1 |
| Uchiyama, M | 1 |
| Shimizu, A | 2 |
| Takahashi, H | 2 |
| Terasaki, Y | 1 |
| Terasaki, M | 1 |
| Kanazawa, S | 1 |
| Kokuho, N | 1 |
| Urushiyama, H | 1 |
| Kajimoto, Y | 1 |
| Kunugi, S | 1 |
| Maruyama, M | 1 |
| Akimoto, T | 1 |
| Miura, Y | 1 |
| Igarashi, T | 2 |
| Ohsawa, I | 8 |
| Ozeki, N | 1 |
| Yamawaki-Ogata, A | 1 |
| Narita, Y | 1 |
| Mii, S | 1 |
| Ushida, K | 1 |
| Ito, M | 8 |
| Hirano, SI | 4 |
| Kurokawa, R | 2 |
| Ohno, K | 7 |
| Usui, A | 1 |
| Yao, L | 4 |
| Chen, H | 13 |
| Wu, Q | 2 |
| Xie, K | 17 |
| Kobayashi, E | 2 |
| Sano, M | 5 |
| Feng, S | 1 |
| Duan, E | 1 |
| Shi, X | 2 |
| Zhang, H | 6 |
| Li, H | 6 |
| Zhao, Y | 6 |
| Chao, L | 1 |
| Zhong, X | 1 |
| Zhang, W | 3 |
| Chen, G | 2 |
| Chen, B | 4 |
| Li, Y | 16 |
| Jiao, Y | 1 |
| Yu, Y | 18 |
| Li, B | 4 |
| Gu, X | 1 |
| Wang, G | 9 |
| Li, L | 8 |
| Liu, T | 4 |
| Liu, L | 9 |
| Li, S | 4 |
| Zhang, Z | 11 |
| Zhang, R | 2 |
| Zhou, Y | 6 |
| Liu, F | 2 |
| Saito, M | 1 |
| Chen-Yoshikawa, TF | 1 |
| Takahashi, M | 2 |
| Kayawake, H | 1 |
| Yokoyama, Y | 1 |
| Date, H | 1 |
| Chen, HG | 2 |
| Han, HZ | 2 |
| Yu, YH | 1 |
| Xie, KL | 3 |
| Wu, Z | 1 |
| Cen, J | 1 |
| Pasca, S | 1 |
| Tomuleasa, C | 1 |
| Yang, Y | 5 |
| Liu, PY | 1 |
| Bao, W | 1 |
| Chen, SJ | 1 |
| Wu, FS | 1 |
| Zhu, PY | 1 |
| Cheng, S | 3 |
| Peng, L | 1 |
| Xu, B | 1 |
| Chen, W | 4 |
| Chen, Y | 4 |
| Gu, Y | 1 |
| Wu, S | 4 |
| Fang, Z | 2 |
| Zhou, S | 1 |
| Niu, Y | 1 |
| Nie, Q | 1 |
| Dong, L | 1 |
| Zhang, J | 10 |
| Liu, SF | 2 |
| Song, W | 1 |
| Wu, G | 3 |
| Song, D | 1 |
| Fu, Z | 1 |
| Wu, X | 3 |
| Dong, A | 1 |
| Yilmaz-Oral, D | 1 |
| Kaya-Sezginer, E | 1 |
| Oztekin, CV | 1 |
| Bayatli, N | 1 |
| Lokman, U | 1 |
| Gur, S | 1 |
| Wei, L | 1 |
| Zhang, XW | 1 |
| Zhu, L | 5 |
| Du, JR | 1 |
| Imamura, R | 2 |
| Kondo, M | 1 |
| Nonomura, N | 2 |
| Halim, AA | 1 |
| Alsayed, B | 1 |
| Embarak, S | 1 |
| Yaseen, T | 1 |
| Dabbous, S | 1 |
| Fontaine, O | 1 |
| Dueluzeau, R | 1 |
| Raibaud, P | 1 |
| Chabanet, C | 1 |
| Popoff, MR | 1 |
| Badoual, J | 1 |
| Gabilan, JC | 1 |
| Andremont, A | 1 |
| Gómez, L | 1 |
| Andrés, S | 1 |
| Sánchez, J | 1 |
| Alonso, JM | 1 |
| Rey, J | 1 |
| López, F | 1 |
| Jiménez, A | 1 |
| Yan, Z | 1 |
| Zhou, L | 2 |
| Huang, L | 4 |
| Hu, K | 1 |
| Liu, H | 6 |
| Wang, H | 6 |
| Guo, Z | 2 |
| Song, Y | 3 |
| Huang, H | 4 |
| Yang, R | 2 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Cheng, T | 1 |
| Zhou, X | 2 |
| Wang, B | 5 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Hashimoto, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 3 |
| Gai, QY | 3 |
| Wang, W | 5 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Aleksic Sabo, V | 1 |
| Knezevic, P | 1 |
| Borges-Argáez, R | 1 |
| Chan-Balan, R | 1 |
| Cetina-Montejo, L | 1 |
| Ayora-Talavera, G | 1 |
| Sansores-Peraza, P | 1 |
| Gómez-Carballo, J | 1 |
| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
| Yu, Z | 1 |
| Zhu, J | 2 |
| Jiang, H | 2 |
| Xiao, Z | 1 |
| Xu, J | 4 |
| Sun, Q | 6 |
| Han, D | 1 |
| Lei, H | 1 |
| Zhao, K | 2 |
| Li, X | 8 |
| Fu, H | 2 |
| Wilson, BK | 1 |
| Step, DL | 1 |
| Maxwell, CL | 1 |
| Gifford, CA | 1 |
| Richards, CJ | 1 |
| Krehbiel, CR | 1 |
| Warner, JM | 1 |
| Doerr, AJ | 1 |
| Erickson, GE | 1 |
| Guretzky, JA | 1 |
| Rasby, RJ | 1 |
| Watson, AK | 1 |
| Klopfenstein, TJ | 1 |
| Liu, Z | 7 |
| Pham, TD | 1 |
| Lee, BK | 1 |
| Yang, FC | 1 |
| Wu, KH | 1 |
| Lin, WP | 1 |
| Hu, MK | 1 |
| Lin, L | 3 |
| Shao, J | 1 |
| Xu, G | 1 |
| Zhang, X | 11 |
| Xu, N | 1 |
| Wang, R | 2 |
| Liu, S | 4 |
| He, H | 1 |
| Dong, X | 5 |
| Yang, M | 4 |
| Yang, Q | 2 |
| Duan, S | 1 |
| Han, J | 2 |
| Zhang, C | 5 |
| Chen, L | 6 |
| Yang, X | 2 |
| Li, W | 5 |
| Wang, T | 4 |
| Campbell, DA | 1 |
| Gao, K | 1 |
| Zager, RA | 1 |
| Johnson, ACM | 1 |
| Guillem, A | 1 |
| Keyser, J | 1 |
| Singh, B | 1 |
| Steubl, D | 1 |
| Schneider, MP | 1 |
| Meiselbach, H | 1 |
| Nadal, J | 1 |
| Schmid, MC | 1 |
| Saritas, T | 1 |
| Krane, V | 1 |
| Sommerer, C | 1 |
| Baid-Agrawal, S | 1 |
| Voelkl, J | 1 |
| Kotsis, F | 1 |
| Köttgen, A | 1 |
| Eckardt, KU | 1 |
| Scherberich, JE | 1 |
| Sun, L | 4 |
| Zhu, Z | 2 |
| Naren, N | 1 |
| Zhang, XX | 2 |
| Gentile, GL | 1 |
| Rupert, AS | 1 |
| Carrasco, LI | 1 |
| Garcia, EM | 1 |
| Kumar, NG | 1 |
| Walsh, SW | 1 |
| Jefferson, KK | 1 |
| Guest, RL | 1 |
| Samé Guerra, D | 1 |
| Wissler, M | 1 |
| Grimm, J | 1 |
| Silhavy, TJ | 1 |
| Lee, JH | 2 |
| Yoo, JS | 1 |
| Kim, Y | 1 |
| Kim, JS | 2 |
| Lee, EJ | 1 |
| Roe, JH | 1 |
| Delorme, M | 1 |
| Bouchard, PA | 1 |
| Simon, M | 1 |
| Simard, S | 1 |
| Lellouche, F | 1 |
| D'Urzo, KA | 1 |
| Mok, F | 1 |
| D'Urzo, AD | 1 |
| Koneru, B | 1 |
| Lopez, G | 1 |
| Farooqi, A | 1 |
| Conkrite, KL | 1 |
| Nguyen, TH | 1 |
| Macha, SJ | 1 |
| Modi, A | 1 |
| Rokita, JL | 1 |
| Urias, E | 1 |
| Hindle, A | 1 |
| Davidson, H | 1 |
| Mccoy, K | 1 |
| Nance, J | 1 |
| Yazdani, V | 1 |
| Irwin, MS | 1 |
| Yang, S | 2 |
| Wheeler, DA | 1 |
| Maris, JM | 1 |
| Diskin, SJ | 1 |
| Reynolds, CP | 1 |
| Abhilash, L | 1 |
| Kalliyil, A | 1 |
| Sheeba, V | 1 |
| Hartley, AM | 2 |
| Meunier, B | 2 |
| Pinotsis, N | 1 |
| Maréchal, A | 2 |
| Xu, JY | 1 |
| Genko, N | 1 |
| Haraux, F | 1 |
| Rich, PR | 1 |
| Kamalanathan, M | 1 |
| Doyle, SM | 1 |
| Xu, C | 1 |
| Achberger, AM | 1 |
| Wade, TL | 1 |
| Schwehr, K | 1 |
| Santschi, PH | 1 |
| Sylvan, JB | 1 |
| Quigg, A | 1 |
| Leong, W | 1 |
| Xu, W | 3 |
| Gao, S | 3 |
| Zhai, X | 1 |
| Wang, C | 6 |
| Gilson, E | 1 |
| Ye, J | 1 |
| Lu, Y | 2 |
| Yan, R | 1 |
| Hu, Z | 1 |
| You, Q | 1 |
| Cai, Q | 1 |
| Yang, D | 1 |
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| Starenki, D | 1 |
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| Wang, Y | 13 |
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| de Carvalho, PA | 1 |
| Prudente, DO | 1 |
| de Souza, LB | 1 |
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| Paiva, R | 1 |
| Marchiori, PER | 1 |
| Lu, M | 2 |
| An, Z | 1 |
| Jiang, J | 2 |
| Du, S | 1 |
| Zhou, H | 3 |
| Cui, J | 1 |
| Wu, W | 2 |
| Song, J | 1 |
| Lian, Q | 1 |
| Uddin Ahmad, Z | 1 |
| Gang, DD | 1 |
| Konggidinata, MI | 1 |
| Gallo, AA | 1 |
| Zappi, ME | 1 |
| Yang, TWW | 1 |
| Johari, Y | 1 |
| Burton, PR | 1 |
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| Shaw, K | 1 |
| Hare, JL | 1 |
| Brown, WA | 1 |
| Kim, GA | 1 |
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| Choi, GH | 1 |
| Choi, J | 1 |
| Lim, YS | 1 |
| Gallo, A | 1 |
| Cancelli, C | 1 |
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| Covino, M | 1 |
| Capoluongo, E | 1 |
| Pocino, K | 1 |
| Ianiro, G | 1 |
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| Gasbarrini, A | 1 |
| Montalto, M | 1 |
| Somasundar, Y | 1 |
| Lu, IC | 1 |
| Mills, MR | 1 |
| Qian, LY | 1 |
| Olivares, X | 1 |
| Ryabov, AD | 1 |
| Collins, TJ | 1 |
| Zhao, L | 1 |
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| Thomas, AM | 1 |
| Nikolayev, AA | 1 |
| Galimova, GR | 1 |
| Azyazov, VN | 1 |
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| Guo, S | 2 |
| Yang, P | 1 |
| Yu, X | 2 |
| Wu, Y | 3 |
| Yu, B | 2 |
| Han, B | 3 |
| George, MW | 1 |
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| Hanke, I | 1 |
| Ganschow, S | 1 |
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| Schlom, DG | 1 |
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| Hayton, TW | 1 |
| Becker, B | 1 |
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| Gross, AJ | 1 |
| Laukhtina, E | 1 |
| Glybochko, P | 1 |
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| Shi, J | 2 |
| Carreno, J | 1 |
| Kloner, RA | 1 |
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| Kim, EH | 1 |
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| Fan, Y | 3 |
| Sun, YB | 1 |
| Wang, AL | 1 |
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| Guo, SW | 1 |
| Wáng, YXJ | 1 |
| Sun, J | 3 |
| Chu, S | 1 |
| Pan, Q | 1 |
| Li, D | 2 |
| Zheng, S | 2 |
| Ma, L | 1 |
| Wang, L | 6 |
| Hu, T | 1 |
| Wang, F | 2 |
| Han, Z | 1 |
| Yin, Z | 1 |
| Ge, X | 1 |
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| Hao, P | 1 |
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| Zhao, S | 5 |
| Luo, XM | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety of Hydrogen Inhalation on Bronchiectasis (HYBRID): A Randomized, Multi-center, Double-blind, Parallel-group Study[NCT02765295] | 120 participants (Anticipated) | Interventional | 2016-06-01 | Recruiting | |||
| Adjuvant Therapy for Severe COPD Patients in the Stable Phase by an Oxyhydrogen Generator With Nebulizer: A Multi-centric, Randomized, Parallel-control and Double-blinded Clinic Study[NCT02850185] | 170 participants (Anticipated) | Interventional | 2016-07-15 | Recruiting | |||
| Adjuvant Therapy for Severe Asthma by an Oxyhydrogen Generator With Nebulizer: A Multi-centric, Randomized, Parallel-control and Double-blinded Clinic Study on Effectiveness and Safety[NCT02883582] | 150 participants (Anticipated) | Interventional | 2016-08-31 | Recruiting | |||
| Medium-term Effects of Molecular Hydrogen on Metabolic Fitness in Obesity[NCT02832219] | Phase 3 | 12 participants (Actual) | Interventional | 2016-01-31 | Completed | ||
| [NCT02830854] | Phase 3 | 13 participants (Actual) | Interventional | 2016-07-31 | Completed | ||
| [NCT01759498] | Phase 2 | 36 participants (Actual) | Interventional | 2012-12-31 | Completed | ||
| Evaluation of the Daily Intake of 0.5 L of Water Saturated With Molecular Hydrogen for 21 Days in COVID-19 Patients Treated in Ambulatory Care. Double-blind, Randomized, Comparative Study[NCT04716985] | 700 participants (Actual) | Interventional | 2021-01-22 | Active, not recruiting | |||
| The Effect of Perioperative Hydrogen Inhalation on Post-operative Pain and Inflammation Cytokines[NCT05476575] | 32 participants (Anticipated) | Interventional | 2021-10-28 | Recruiting | |||
| Metabolomic Profile of Patients Undergoing Myocardial Perfusion SPECT[NCT02968771] | 500 participants (Anticipated) | Observational | 2016-11-30 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 reviews available for hydrogen and Disease Models, Animal
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Medical Application of Hydrogen in Hematological Diseases.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Disease Models, Animal; Humans; Hydrogen | 2019 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
To solve our new emergency care crisis, let's start with the old one.
Topics: Animals; Argon; Carbon Monoxide; Disease Models, Animal; Emergency Medical Services; Helium; Humans; | 2020 |
Circulating messenger for neuroprotection induced by molecular hydrogen.
Topics: Animals; Blood-Brain Barrier; Disease Models, Animal; Drinking; Gastric Mucosa; Ghrelin; Humans; Hyd | 2019 |
Hydrogen-rich saline ameliorates lung injury associated with cecal ligation and puncture-induced sepsis in rats.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Cecum; Disease Models, Animal; D | 2015 |
Recent advances in hydrogen research as a therapeutic medical gas.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomedical Research; Chemical Industry; Chemopreven | 2010 |
Molecular hydrogen as an emerging therapeutic medical gas for neurodegenerative and other diseases.
Topics: Animals; Brain Diseases; Disease Models, Animal; Gases; Humans; Hydrogen; Metabolic Diseases; Neurod | 2012 |
Molecular hydrogen as an emerging therapeutic medical gas for neurodegenerative and other diseases.
Topics: Animals; Brain Diseases; Disease Models, Animal; Gases; Humans; Hydrogen; Metabolic Diseases; Neurod | 2012 |
Molecular hydrogen as an emerging therapeutic medical gas for neurodegenerative and other diseases.
Topics: Animals; Brain Diseases; Disease Models, Animal; Gases; Humans; Hydrogen; Metabolic Diseases; Neurod | 2012 |
Molecular hydrogen as an emerging therapeutic medical gas for neurodegenerative and other diseases.
Topics: Animals; Brain Diseases; Disease Models, Animal; Gases; Humans; Hydrogen; Metabolic Diseases; Neurod | 2012 |
Magnetic resonance spectroscopy in animal models of epilepsy.
Topics: Animals; Aspartic Acid; Brain; Carbon Isotopes; Choline; Creatine; Disease Models, Animal; Epilepsy; | 2007 |
Proton magnetic resonance spectroscopy: the new gold standard for diagnosis of clinical and subclinical hepatic encephalopathy?
Topics: Animals; Astrocytes; Brain; Choline; Cognition Disorders; Disease Models, Animal; Glutamine; Hepatic | 1996 |
The pharmacology of anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Biotransformation; Brain; Disease Models, Animal; Electric Stimulation; En | 1978 |
[An experimental model of renal tubular acidosis--with special reference to distal renal tubular acidosis].
Topics: Acidosis, Renal Tubular; Aldosterone; Amiloride; Amphotericin B; Animals; Carbon Dioxide; Disease Mo | 1985 |
3 trials available for hydrogen and Disease Models, Animal
| Article | Year |
|---|---|
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp | 2023 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment.
Topics: Administration, Oral; Aged; Aldehyde Dehydrogenase, Mitochondrial; Animals; Antioxidants; Apolipopro | 2018 |
220 other studies available for hydrogen and Disease Models, Animal
| Article | Year |
|---|---|
Adsorptivity of cationic cellulose nanocrystals for phosphate and its application in hyperphosphatemia therapy.
Topics: Adenine; Adsorption; Animals; Biomarkers; Cellulose; Chelating Agents; Cholesterol, HDL; Cholesterol | 2021 |
Preparation and evaluation of colon adhesive pellets of 5-aminosalicylic acid.
Topics: Acrylic Resins; Adhesiveness; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal | 2014 |
Boswellia carterii liquisolid systems with promoted anti-inflammatory activity.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Boswellia; Carrageenan; Cellulose; Chemistr | 2015 |
Prenatal Molecular Hydrogen Administration Ameliorates Several Findings in Nitrofen-Induced Congenital Diaphragmatic Hernia.
Topics: Animals; Animals, Newborn; Antioxidants; Deuterium Oxide; Disease Models, Animal; Female; Hernias, D | 2021 |
Hydrogen-Rich Water Ameliorates Murine Chronic Graft-versus-Host Disease through Antioxidation.
Topics: Animals; Antioxidants; Disease Models, Animal; Graft vs Host Disease; Hydrogen; Male; Mice; Water | 2021 |
Hydrogen-Rich Water Improves Cognitive Ability and Induces Antioxidative, Antiapoptotic, and Anti-Inflammatory Effects in an Acute Ischemia-Reperfusion Injury Mouse Model.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Brain Ischemia; Cognition; Deuterium Oxi | 2021 |
High concentration of hydrogen ameliorates lipopolysaccharide-induced acute lung injury in a sirt1-dependent manner.
Topics: Acute Lung Injury; Administration, Inhalation; Animals; Disease Models, Animal; Endothelial Cells; H | 2022 |
The Anti-Inflammatory Effect of Hydrogen Gas Inhalation and Its Influence on Laser-Induced Choroidal Neovascularization in a Mouse Model of Neovascular Age-Related Macular Degeneration.
Topics: Administration, Inhalation; Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Choroidal Ne | 2021 |
Hydrogen-rich water partially alleviate inflammation, oxidative stress and intestinal flora dysbiosis in DSS-induced chronic ulcerative colitis mice.
Topics: Animals; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Dysbiosis; Gastrointestinal M | 2022 |
Gender-based differences in neuroprotective effects of hydrogen gas against intracerebral hemorrhage-induced depression.
Topics: Animals; Cerebral Hemorrhage; Depression; Disease Models, Animal; Female; Humans; Hydrogen; Male; Mi | 2022 |
Hydrogen-generating Si-based agent protects against skin flap ischemia-reperfusion injury in rats.
Topics: Animals; Disease Models, Animal; Hydrogen; Inflammation; Rats; Rats, Sprague-Dawley; Reperfusion Inj | 2022 |
A new therapy against ulcerative colitis via the intestine and brain using the Si-based agent.
Topics: Animals; Antioxidants; Brain; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; H | 2022 |
Prophylactic Instillation of Hydrogen-Rich Water Decreases Corneal Inflammation and Promotes Wound Healing by Activating Antioxidant Activity in a Rat Alkali Burn Model.
Topics: Alkalies; Animals; Antioxidants; Burns, Chemical; Corneal Injuries; Disease Models, Animal; Eye Burn | 2022 |
Effect of H
Topics: Animals; Arthritis, Rheumatoid; bcl-2-Associated X Protein; Cattle; Collagen Type II; Cytokines; Dis | 2019 |
Hydrogen water alleviates obliterative airway disease in mice.
Topics: Airway Obstruction; Allografts; Animals; Bronchiolitis Obliterans; Disease Models, Animal; Enzyme-Li | 2020 |
Hydrogen-rich saline alleviates inflammation and apoptosis in myocardial I/R injury via PINK-mediated autophagy.
Topics: Animals; Apoptosis; Autophagy; Biomarkers; Cytokines; Disease Models, Animal; Gene Silencing; Hydrog | 2019 |
Organ preservation solution containing dissolved hydrogen gas from a hydrogen-absorbing alloy canister improves function of transplanted ischemic kidneys in miniature pigs.
Topics: Alloys; Animals; Disease Models, Animal; Gases; Graft Survival; Humans; Hydrogen; Ischemia; Kidney; | 2019 |
Hydrogen ameliorates lung injury in a rat model of subacute exposure to concentrated ambient PM2.5 via Aryl hydrocarbon receptor.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Cytokines; Disease Models, Animal; Hydrogen; | 2019 |
Inhaling Hydrogen Ameliorates Early Postresuscitation EEG Characteristics in an Asphyxial Cardiac Arrest Rat Model.
Topics: Animals; Asphyxia; Cardiopulmonary Resuscitation; Coma; Disease Models, Animal; Electroencephalograp | 2019 |
Protective effects of hydrogen‑rich saline against experimental diabetic peripheral neuropathy via activation of the mitochondrial ATP‑sensitive potassium channel channels in rats.
Topics: Adenosine Triphosphate; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Mod | 2020 |
Effect of hydrogen-rich water on the Nrf2/ARE signaling pathway in rats with myocardial ischemia-reperfusion injury.
Topics: Animals; Disease Models, Animal; Humans; Hydrogen; Male; Myocardial Reperfusion Injury; NF-E2-Relate | 2019 |
Protective effects of a hydrogen-rich solution during cold ischemia in rat lung transplantation.
Topics: Animals; Cold Ischemia; Cytokines; Disease Models, Animal; Hydrogen; Lung; Lung Transplantation; Mal | 2020 |
Hydrogen alleviated organ injury and dysfunction in sepsis: The role of cross-talk between autophagy and endoplasmic reticulum stress: Experimental research.
Topics: Animals; Autophagy; Disease Models, Animal; Drug Evaluation, Preclinical; Endoplasmic Reticulum Stre | 2020 |
Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway.
Topics: Animals; Caspase 1; Cell Line; Disease Models, Animal; Endometrial Neoplasms; Female; Heterografts; | 2020 |
Protective Effects of Hydrogen-Rich Water Against Cartilage Damage in a Rat Model of Osteoarthritis by Inhibiting Oxidative Stress, Matrix Catabolism, and Apoptosis.
Topics: ADAM Proteins; Aggrecans; Animals; Apoptosis; bcl-2-Associated X Protein; Cartilage, Articular; Casp | 2020 |
Saturated hydrogen alleviates CCl
Topics: Acute Kidney Injury; Animals; Carbon Tetrachloride Poisoning; Disease Models, Animal; Hydrogen; Infl | 2020 |
Hydrogen Attenuates Allergic Inflammation by Reversing Energy Metabolic Pathway Switch.
Topics: Animals; Asthma; Bronchoconstrictor Agents; Cells, Cultured; Disease Models, Animal; Female; Glycoly | 2020 |
Hydrogen-Rich Saline Inhibits Lipopolysaccharide-Induced Acute Lung Injury and Endothelial Dysfunction by Regulating Autophagy through mTOR/TFEB Signaling Pathway.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Apoptosis; Autophagy; Basic Helix-Loop-Helix L | 2020 |
Protective Effects of Hydrogen on Myocardial Mitochondrial Functions in Septic Mice.
Topics: Animals; Disease Models, Animal; Heme Oxygenase-1; Hydrogen; Male; Membrane Proteins; Mice; Mice, Kn | 2020 |
Evaluation of combined therapeutic effects of hydrogen sulfide donor sodium hydrogen sulfide and phosphodiesterase type-5 inhibitor tadalafil on erectile dysfunction in a partially bladder outlet obstructed rat model.
Topics: Animals; Disease Models, Animal; Erectile Dysfunction; Hydrogen; Hydrogen Sulfide; Male; Muscle, Smo | 2020 |
[Effects of Low Concentration Hydrogen Inhalation on Asthma and Sleep Function in Mice].
Topics: Administration, Inhalation; Animals; Asthma; Bronchoalveolar Lavage Fluid; Disease Models, Animal; H | 2020 |
Renoprotective and neuroprotective effects of enteric hydrogen generation from Si-based agent.
Topics: Animals; Disease Models, Animal; Hydrogen; Kidney; Male; Mice; Neuroprotective Agents; Oxidative Str | 2020 |
Constitutive hydrogen inhalation prevents vascular remodeling via reduction of oxidative stress.
Topics: Administration, Inhalation; Animals; Disease Models, Animal; DNA Damage; Down-Regulation; Gases; Hum | 2020 |
Chronic molecular hydrogen inhalation mitigates short and long-term memory loss in polymicrobial sepsis.
Topics: Administration, Inhalation; Animals; Antioxidants; Apoptosis; Brain; Disease Models, Animal; Hippoca | 2020 |
Hydrogen Gas Alleviates Sepsis-Induced Brain Injury by Improving Mitochondrial Biogenesis Through the Activation of PGC-α in Mice.
Topics: Animals; Brain Injuries; Disease Models, Animal; DNA-Binding Proteins; High Mobility Group Proteins; | 2021 |
An Immunohistochemical Study of the Increase in Antioxidant Capacity of Corneal Epithelial Cells by Molecular Hydrogen, Leading to the Suppression of Alkali-Induced Oxidative Stress.
Topics: Alkalies; Animals; Antioxidants; Burns, Chemical; Cornea; Corneal Neovascularization; Disease Models | 2020 |
Hydrogen-rich saline mitigates pressure overload-induced cardiac hypertrophy and atrial fibrillation in rats via the JAK-STAT signalling pathway.
Topics: Animals; Atrial Fibrillation; Cardiomegaly; Disease Models, Animal; Hydrogen; Myocytes, Cardiac; Rat | 2020 |
Hydrogen Gas Inhalation Attenuates Endothelial Glycocalyx Damage and Stabilizes Hemodynamics in a Rat Hemorrhagic Shock Model.
Topics: Animals; Arterial Pressure; Disease Models, Animal; Glycocalyx; Hemodynamics; Hydrogen; Rats; Shock, | 2020 |
Hydrogen inhalation inhibits microglia activation and neuroinflammation in a rat model of traumatic brain injury.
Topics: Animals; Brain; Brain Injuries, Traumatic; Disease Models, Animal; Hydrogen; Inflammation; Male; Mic | 2020 |
Longitudinal multiparametric MRI study of hydrogen-enriched water with minocycline combination therapy in experimental ischemic stroke in rats.
Topics: Animals; Brain; Disease Models, Animal; Hydrogen; Ischemic Stroke; Male; Minocycline; Multiparametri | 2020 |
Hydrogen inhalation alleviates nonalcoholic fatty liver disease in metabolic syndrome rats.
Topics: Administration, Inhalation; Animals; Body Mass Index; Diet, Carbohydrate Loading; Diet, High-Fat; Di | 2020 |
Inhaled H
Topics: Acidosis; Administration, Inhalation; Animals; Animals, Newborn; Apoptosis Inducing Factor; Asphyxia | 2020 |
Hydrogen-Rich Saline Regulates Microglial Phagocytosis and Restores Behavioral Deficits Following Hypoxia-Ischemia Injury in Neonatal Mice via the Akt Pathway.
Topics: Animals; Animals, Newborn; Apoptosis; Disease Models, Animal; Female; Hydrogen; Hypoxia-Ischemia, Br | 2020 |
Effects of long-term hydrogen intervention on the physiological function of rats.
Topics: Animals; Blood Glucose; Body Weight; China; Disease Models, Animal; Heart; Hydrogen; Liver; Male; My | 2020 |
Efficacy of a Si-based agent against developing renal failure in a rat remnant kidney model.
Topics: Administration, Oral; Animals; Antioxidants; Caspase 3; Cell Hypoxia; Creatinine; Disease Models, An | 2020 |
Hydrogen Gas Therapy Attenuates Inflammatory Pathway Signaling in Septic Mice.
Topics: Administration, Inhalation; Animals; Disease Models, Animal; Humans; Hydrogen; Male; Mice; RNA-Seq; | 2021 |
Hydrogen Attenuates Endotoxin-Induced Lung Injury by Activating Thioredoxin 1 and Decreasing Tissue Factor Expression.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Coculture Techniques; Disease Models, Animal; | 2021 |
Peritoneal lavage with hydrogen-rich saline can be an effective and practical procedure for acute peritonitis.
Topics: Acute Disease; Animals; Antioxidants; Disease Models, Animal; Free Radical Scavengers; Hydrogen; Mal | 2021 |
Pre-inhalation of hydrogen-rich gases protect against caerulein-induced mouse acute pancreatitis while enhance the pancreatic Hsp60 protein expression.
Topics: Administration, Inhalation; Animals; Ceruletide; Chaperonin 60; Disease Models, Animal; Female; Gase | 2021 |
Reshaping of bacterial molecular hydrogen metabolism contributes to the outgrowth of commensal
Topics: Animals; Cecum; Colitis; Colon; Databases, Genetic; Dextran Sulfate; Disease Models, Animal; Dysbios | 2021 |
Protective effects of hydrogen gas against spinal cord ischemia-reperfusion injury.
Topics: Amino Acid Transport System X-AG; Animals; Disease Models, Animal; Glutamates; Hydrogen; Ischemia; M | 2022 |
Molecular Hydrogen Attenuated N-methyl-N-Nitrosourea Induced Corneal Endothelial Injury by Upregulating Anti-Apoptotic Pathway.
Topics: Animals; Apoptosis; Cell Count; Cells, Cultured; Corneal Injuries; Disease Models, Animal; Endotheli | 2021 |
Hydrogen Attenuates Myocardial Injury in Rats by Regulating Oxidative Stress and NLRP3 Inflammasome Mediated Pyroptosis.
Topics: Administration, Inhalation; Animals; Antioxidants; Disease Models, Animal; Echocardiography; Humans; | 2021 |
Hydrogen-rich saline attenuates anxiety-like behaviors in morphine-withdrawn mice.
Topics: Adaptation, Ocular; Animals; Anti-Anxiety Agents; Anxiety; Corticosterone; Disease Models, Animal; D | 2017 |
Therapeutic effects of hydrogen on chronic graft-versus-host disease.
Topics: Animals; Bone Marrow Transplantation; Chronic Disease; Disease Models, Animal; Graft vs Host Disease | 2017 |
Molecular Hydrogen Effectively Heals Alkali-Injured Cornea via Suppression of Oxidative Stress.
Topics: Actins; Animals; Cornea; Corneal Injuries; Cytokines; Disease Models, Animal; Female; Gene Expressio | 2017 |
Hydrogen-rich saline attenuates spinal cord hemisection-induced testicular injury in rats.
Topics: Animals; Apoptosis; Biomarkers; Disease Models, Animal; Gene Expression; Germ Cells; GTP Phosphohydr | 2017 |
[The protection of hydrogen-rich saline on a rat dry eye model induced by scopolamine hydrobromide].
Topics: Animals; Conjunctiva; Cornea; Disease Models, Animal; Dry Eye Syndromes; Epithelium; Female; Hydroge | 2017 |
Hydrogen coadministration slows the development of COPD-like lung disease in a cigarette smoke-induced rat model.
Topics: Administration, Inhalation; Animals; Anti-Inflammatory Agents; Apoptosis Regulatory Proteins; Cigare | 2017 |
Molecular mechanisms underlying the protective effects of hydrogen-saturated saline on noise-induced hearing loss.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cochlea; Cytokines; Deoxyguanosine; Disease Models, Animal; Ev | 2017 |
Hydrogen gas inhalation inhibits progression to the "irreversible" stage of shock after severe hemorrhage in rats.
Topics: Administration, Inhalation; Animals; Disease Models, Animal; Disease Progression; Hydrogen; Male; Ra | 2017 |
Anti-oxidant and anti-inflammatory effects of hydrogen-rich water alleviate ethanol-induced fatty liver in mice.
Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Cytokines; Disease Models, | 2017 |
Hydrogen-rich saline inhibits tobacco smoke-induced chronic obstructive pulmonary disease by alleviating airway inflammation and mucus hypersecretion in rats.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Bronchoalveolar Lavage Fluid; Cytokines; Disea | 2017 |
Protection by Inhaled Hydrogen Therapy in a Rat Model of Acute Lung Injury can be Tracked in vivo Using Molecular Imaging.
Topics: Acute Lung Injury; Administration, Inhalation; Animals; Bacteriocins; Disease Models, Animal; Hydrog | 2017 |
Effect of Hydrogen-Rich Saline on Postoperative Intra-Abdominal Adhesion Bands Formation in Mice.
Topics: Abdominal Cavity; Animals; Cecum; Cytokines; Disease Models, Animal; Hydrogen; Interleukin-6; Male; | 2017 |
Hyperoxygenated hydrogen-rich solution suppresses shock- and resuscitation-induced liver injury.
Topics: Animals; Cytokines; Disease Models, Animal; Hepatic Insufficiency; Hydrogen; Liver; Male; Oxygen; Ra | 2017 |
Hydrogen Treatment Protects Mice Against Chronic Pancreatitis by Restoring Regulatory T Cells Loss.
Topics: Adoptive Transfer; Amylases; Animals; Antibodies, Neutralizing; Arginine; Cell Survival; Disease Mod | 2017 |
Hydrogen Inhalation is Superior to Mild Hypothermia for Improving Neurological Outcome and Survival in a Cardiac Arrest Model of Spontaneously Hypertensive Rat.
Topics: Administration, Inhalation; Animals; Cardiopulmonary Resuscitation; Disease Models, Animal; Heart Ar | 2018 |
Hydrogen-Rich Saline Regulates Intestinal Barrier Dysfunction, Dysbiosis, and Bacterial Translocation in a Murine Model of Sepsis.
Topics: Animals; Bacterial Translocation; Disease Models, Animal; Dysbiosis; Enterobacteriaceae; Hydrogen; I | 2018 |
Protective effect of hydrogen-rich saline on pressure overload-induced cardiac hypertrophyin rats: possible role of JAK-STAT signaling.
Topics: Animals; Aorta, Abdominal; Apoptosis; Arterial Pressure; Atrial Natriuretic Factor; Cardiomegaly; Co | 2018 |
Hydrogen Gas Does Not Ameliorate Renal Ischemia Reperfusion Injury in a Preclinical Model.
Topics: Animals; Cold Ischemia; Disease Models, Animal; Hydrogen; Kidney; Kidney Transplantation; Oxidative | 2018 |
Kidney Response to the Spectrum of Diet-Induced Acid Stress.
Topics: Acid-Base Equilibrium; Acidosis; Animals; Diet; Dietary Proteins; Disease Models, Animal; Glomerular | 2018 |
Effects of Post-Treatment Hydrogen Gas Inhalation on Uveitis Induced by Endotoxin in Rats.
Topics: Animals; Aqueous Humor; Calcium-Binding Proteins; Ciliary Body; Disease Models, Animal; Endotoxins; | 2018 |
FoxO1-mediated autophagy plays an important role in the neuroprotective effects of hydrogen in a rat model of vascular dementia.
Topics: Animals; Apoptosis; Autophagy; Beclin-1; Brain Ischemia; CA1 Region, Hippocampal; Caspase 3; Cogniti | 2019 |
Hydrogen-Rich Saline Activated Autophagy via HIF-1
Topics: Animals; Autophagy; Disease Models, Animal; Hydrogen; Hypoxia-Inducible Factor 1, alpha Subunit; Mal | 2018 |
Hydrogen-rich water attenuates oxidative stress in rats with traumatic brain injury via Nrf2 pathway.
Topics: Animals; Brain Injuries, Traumatic; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Hy | 2018 |
[Role of Rho/ROCK signaling pathway in the protective effects of hydrogen against acute lung injury in septic mice].
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Hydrogen; Inflamma | 2016 |
Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model.
Topics: Administration, Inhalation; Animals; Apoptosis; Brain; Cerebral Hemorrhage; Disease Models, Animal; | 2018 |
Molecular Hydrogen Prevents Social Deficits and Depression-Like Behaviors Induced by Low-Intensity Blast in Mice.
Topics: Analysis of Variance; Animals; Blast Injuries; Depression; Disease Models, Animal; Exploratory Behav | 2018 |
The healing effect of hydrogen-rich water on acute radiation-induced skin injury in rats.
Topics: Animals; Disease Models, Animal; Down-Regulation; Electrons; Epidermal Growth Factor; Hydrogen; Inte | 2019 |
Hydrogen ventilation combined with mild hypothermia improves short-term neurological outcomes in a 5-day neonatal hypoxia-ischaemia piglet model.
Topics: Animals; Animals, Newborn; Antioxidants; Asphyxia Neonatorum; Brain; Disease Models, Animal; Humans; | 2019 |
Attenuation of Cardiac Ischaemia-reperfusion Injury by Treatment with Hydrogen-rich Water.
Topics: Animals; Apoptosis; Biomarkers; Cell Membrane; Computational Biology; Disease Models, Animal; Gene E | 2019 |
Hydrogen Gas Alleviates Chronic Intermittent Hypoxia-Induced Renal Injury through Reducing Iron Overload.
Topics: Acute Kidney Injury; Animals; Apoptosis; Cation Transport Proteins; Cell Hypoxia; Ceruloplasmin; Dis | 2019 |
Protective Effect of Hydrogen Gas Inhalation on Muscular Damage Using a Mouse Hindlimb Ischemia-Reperfusion Injury Model.
Topics: Administration, Inhalation; Animals; Disease Models, Animal; Hindlimb; Humans; Hydrogen; Male; Mice; | 2017 |
Effects of hydrogen-rich water in a rat model of polycystic kidney disease.
Topics: Administration, Oral; Animals; Disease Models, Animal; Drinking; Humans; Hydrogen; Kidney; Mutation; | 2019 |
Molecular hydrogen accelerates the reversal of acute obstructive cholangitis‑induced liver dysfunction by restoring gap and tight junctions.
Topics: Acute Disease; Alanine Transaminase; Animals; Aspartate Aminotransferases; Cholangitis; Connexins; D | 2019 |
Hydrogen Alleviates Necroptosis and Cognitive Deficits in Lithium-Pilocarpine Model of Status Epilepticus.
Topics: Animals; Apoptosis; CA1 Region, Hippocampal; Cognition Disorders; Disease Models, Animal; Hydrogen; | 2019 |
Protective effects of hydrogen gas in a rat model of branch retinal vein occlusion via decreasing VEGF-α expression.
Topics: Animals; Disease Models, Animal; Electroretinography; Hydrogen; Male; Oxidative Stress; Rats; Rats, | 2019 |
Molecular hydrogen suppresses glioblastoma growth via inducing the glioma stem-like cell differentiation.
Topics: Animals; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Self Renewa | 2019 |
Protective effects of hydrogen inhalation during the warm ischemia phase against lung ischemia-reperfusion injury in rat donors after cardiac death.
Topics: Administration, Inhalation; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Disease Mode | 2019 |
Preconditioning with one-time hydrogen gas does not attenuate skin flap ischemia-reperfusion injury in rat models.
Topics: Analysis of Variance; Animals; Biopsy, Needle; Disease Models, Animal; Epigastric Arteries; Graft Re | 2019 |
The effect of hydrogen gas on a mouse bilateral common carotid artery occlusion.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Analysis of Variance; Animals; Arterial Occlusive Diseases; Brain Edema | 2013 |
Beneficial effects of hydrogen-rich saline against spinal cord ischemia-reperfusion injury in rabbits.
Topics: Acyl Coenzyme A; Animals; Caspase 3; Catalase; Cytokines; Dinoprost; Disease Models, Animal; Dose-Re | 2013 |
Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma.
Topics: Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; | 2013 |
Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma.
Topics: Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; | 2013 |
Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma.
Topics: Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; | 2013 |
Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma.
Topics: Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; | 2013 |
Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma.
Topics: Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; | 2013 |
Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma.
Topics: Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; | 2013 |
Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma.
Topics: Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; | 2013 |
Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma.
Topics: Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; | 2013 |
Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma.
Topics: Airway Remodeling; Animals; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; | 2013 |
[The effect of hydrogen on hemorrhagic shock induced acute lung injury in rats].
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Hydrogen; Interleukin-6; Lung; Male; Malondialde | 2013 |
Breathing nitric oxide plus hydrogen gas reduces ischemia-reperfusion injury and nitrotyrosine production in murine heart.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Inhalation; Aldehydes; Animals; Antioxidants; Cardioton | 2013 |
Protective effects of hydrogen-rich saline on ulcerative colitis rat model.
Topics: Acetic Acid; Animals; Antioxidants; Colitis, Ulcerative; Disease Models, Animal; Hydrogen; Injection | 2013 |
Delayed neurovascular dysfunction is alleviated by hydrogen in asphyxiated newborn pigs.
Topics: Animals; Animals, Newborn; Arterioles; Asphyxia Neonatorum; Blood Gas Analysis; Brain Waves; Disease | 2013 |
[Suppression of experimental abdominal aortic aneurysm by saturated hydrogen saline: a preliminary study with rats].
Topics: Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Disease Models, Animal; Hydrogen; Interleukin | 2013 |
Saturated hydrogen saline attenuates endotoxin-induced acute liver dysfunction in rats.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Biomarkers; Carrier Proteins; Disease Models, Ani | 2013 |
Therapeutic effects of hydrogen-rich solution on aplastic anemia in vivo.
Topics: Anemia, Aplastic; Animals; Blood Cells; Body Weight; Bone Marrow; Bone Marrow Cells; CD4-Positive T- | 2013 |
[A study on residual strain of abdominal aortic aneurysm after intraperitoneal administration of saturated hydrogen saline in rats].
Topics: Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Biomechanical Phenomena; Disease Models, Anim | 2013 |
Nuclear factor-κB/Bcl-XL pathway is involved in the protective effect of hydrogen-rich saline on the brain following experimental subarachnoid hemorrhage in rabbits.
Topics: Animals; Apoptosis; bcl-X Protein; Blotting, Western; Disease Models, Animal; Electrophoretic Mobili | 2013 |
Microbiota-derived hydrogen fuels Salmonella typhimurium invasion of the gut ecosystem.
Topics: Animals; Disease Models, Animal; DNA Transposable Elements; Gastrointestinal Tract; Hydrogen; Hydrog | 2013 |
Pretreatment with hydrogen-rich saline reduces the damage caused by glycerol-induced rhabdomyolysis and acute kidney injury in rats.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Creatine Kinase; Disease Model | 2014 |
[Suppression of abdominal aortic aneurysm by hydrogen through chemokine-like factor1].
Topics: Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Chemokines; Disease Models, Animal; Hydrogen; | 2014 |
Effect of hydrogen-rich water on acute peritonitis of rat models.
Topics: Acute Disease; Animals; Cecum; Disease Models, Animal; Endotoxins; Feces; Humans; Hydrogen; Interleu | 2014 |
Beneficial effects of hydrogen gas on porcine liver reperfusion injury with use of total vascular exclusion and active venous bypass.
Topics: Animals; Antioxidants; Aspartate Aminotransferases; Biomarkers; Disease Models, Animal; Female; Gase | 2014 |
[The role of Nrf2 in the hydrogen treatment for intestinal injury caused by severe sepsis].
Topics: Animals; Disease Models, Animal; HMGB1 Protein; Hydrogen; Intestinal Mucosa; Intestines; Male; Mice; | 2014 |
Hydrogen-rich saline promotes survival of retinal ganglion cells in a rat model of optic nerve crush.
Topics: Animals; Cell Count; Cell Survival; Disease Models, Animal; Evoked Potentials, Visual; gamma-Synucle | 2014 |
HV1 acts as a sodium sensor and promotes superoxide production in medullary thick ascending limb of Dahl salt-sensitive rats.
Topics: Animals; Disease Models, Animal; Hydrogen; Hydrogen-Ion Concentration; Hypertension; Ion Channels; K | 2014 |
Hydrogen-rich saline improves survival and neurological outcome after cardiac arrest and cardiopulmonary resuscitation in rats.
Topics: Administration, Intravenous; Animals; Antioxidants; Apoptosis; Biomarkers; Blood-Brain Barrier; Brai | 2014 |
[Role of Nrf2 in the protective effects of hydrogen against cerebral dysfunction in septic mice].
Topics: Animals; Brain; Dinoprost; Disease Models, Animal; Hydrogen; Male; Malondialdehyde; Mice; Mice, Inbr | 2014 |
Hydrogen inhalation during normoxic resuscitation improves neurological outcome in a rat model of cardiac arrest independently of targeted temperature management.
Topics: Administration, Inhalation; Animals; Blood Circulation; Body Temperature; Cerebral Cortex; Disease M | 2014 |
Laser speckle and hydrogen gas clearance measurements of optic nerve circulation in albino and pigmented rabbits with or without optic disc atrophy.
Topics: Analysis of Variance; Animals; Blood Flow Velocity; Capillaries; Disease Models, Animal; Endothelin- | 2014 |
Cardioprotective Effect of Hydrogen-rich Saline on Isoproterenol-induced Myocardial Infarction in Rats.
Topics: Analysis of Variance; Animals; Biomarkers; Biopsy, Needle; Cardiotonic Agents; Cytokines; Disease Mo | 2015 |
[Protective effects of inhaled hydrogen gas on cognitive function in mice with sepsis-associated encephalopathy].
Topics: Animals; Cognition; Cognition Disorders; Dinoprost; Disease Models, Animal; Hippocampus; Hydrogen; M | 2014 |
Combination therapy with nitric oxide and molecular hydrogen in a murine model of acute lung injury.
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Disease Models, An | 2015 |
The effects of hydrogen gas inhalation during ex vivo lung perfusion on donor lungs obtained after cardiac death.
Topics: Animals; Cytokines; Death; Disease Models, Animal; Extracorporeal Circulation; Female; Graft Surviva | 2015 |
H2 Treatment Attenuated Pain Behavior and Cytokine Release Through the HO-1/CO Pathway in a Rat Model of Neuropathic Pain.
Topics: Animals; Carbon Monoxide; Cytokines; Disease Models, Animal; Heme Oxygenase-1; Hydrogen; Male; Neura | 2015 |
Hydrogen-rich water protects against acetaminophen-induced hepatotoxicity in mice.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Chemical and Drug Induce | 2015 |
Pharmacological postconditioning with lactic acid and hydrogen rich saline alleviates myocardial reperfusion injury in rats.
Topics: Animals; Apoptosis; Caspase 8; Disease Models, Animal; Female; Hydrogen; Ischemic Postconditioning; | 2015 |
Inhalation of hydrogen gas ameliorates glyoxylate-induced calcium oxalate deposition and renal oxidative stress in mice.
Topics: Administration, Inhalation; Animals; Apoptosis; Disease Models, Animal; Glyoxylates; Hydrogen; Immun | 2015 |
Hydrogen ameliorates pulmonary hypertension in rats by anti-inflammatory and antioxidant effects.
Topics: Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Antioxidants; Cell Proliferation; Diseas | 2015 |
Molecular hydrogen stabilizes atherosclerotic plaque in low-density lipoprotein receptor-knockout mice.
Topics: Animals; Apoptosis; Atherosclerosis; Disease Models, Animal; Endoplasmic Reticulum Stress; Humans; H | 2015 |
Molecular hydrogen protects mice against polymicrobial sepsis by ameliorating endothelial dysfunction via an Nrf2/HO-1 signaling pathway.
Topics: Animals; Apoptosis; Blotting, Western; Cell Survival; Disease Models, Animal; Dose-Response Relation | 2015 |
Effects of intraperitoneal hydrogen injection on nitric oxide synthase mRNA and malondialdehyde following limb ischemia-reperfusion in rabbits.
Topics: Animals; Disease Models, Animal; Extremities; Hydrogen; Injections, Intraperitoneal; Male; Malondial | 2015 |
Preventive Effect of Hydrogen Water on the Development of Detrusor Overactivity in a Rat Model of Bladder Outlet Obstruction.
Topics: Animals; Disease Models, Animal; Hydrogen; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Urina | 2016 |
MAPKs and Hsc70 are critical to the protective effect of molecular hydrogen during the early phase of acute pancreatitis.
Topics: Acute Disease; Animals; Cell Line; Disease Models, Animal; HSC70 Heat-Shock Proteins; Hydrogen; Mice | 2016 |
Postconditioning with inhaled hydrogen promotes survival of retinal ganglion cells in a rat model of retinal ischemia/reperfusion injury.
Topics: Animals; Cell Survival; Disease Models, Animal; Hydrogen; Ischemic Postconditioning; Male; Rats; Rat | 2016 |
[Effect of hydrogen-rich saline on cardiomyocyte autophagy during myocardial ischemia-reperfusion in aged rats].
Topics: Aging; Animals; Autophagy; Disease Models, Animal; Hydrogen; Ischemia; Male; Myocardial Reperfusion | 2015 |
Hydrogen-Rich Saline Attenuates Acute Kidney Injury After Liver Transplantation via Activating p53-Mediated Autophagy.
Topics: Acute Kidney Injury; Animals; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Biomarkers; Cytop | 2016 |
Sirtuin Type 1 Mediates the Retinal Protective Effect of Hydrogen-Rich Saline Against Light-Induced Damage in Rats.
Topics: Animals; Apoptosis; Blotting, Western; Disease Models, Animal; Gene Expression Regulation; Hydrogen; | 2015 |
Hydrogen-Rich Water Intake Accelerates Oral Palatal Wound Healing via Activation of the Nrf2/Antioxidant Defense Pathways in a Rat Model.
Topics: Animals; Antioxidants; Biomarkers; Chemokines; Disease Models, Animal; Drinking Behavior; Gene Expre | 2016 |
Hydrogen-rich water attenuates brain damage and inflammation after traumatic brain injury in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Blood-Brain Barrier; Brain Injuries; Bra | 2016 |
Hydrogen-rich water ameliorates bronchopulmonary dysplasia (BPD) in newborn rats.
Topics: Animals; Animals, Newborn; Bronchopulmonary Dysplasia; Disease Models, Animal; Drinking Water; Human | 2016 |
Hydrogen Inhalation is Superior to Mild Hypothermia in Improving Cardiac Function and Neurological Outcome in an Asphyxial Cardiac Arrest Model of Rats.
Topics: Administration, Inhalation; Animals; Cardiopulmonary Resuscitation; Disease Models, Animal; Female; | 2016 |
Colonic Fermentation Promotes Decompression sickness in Rats.
Topics: Animal Feed; Animals; Decompression Sickness; Disease Models, Animal; Fasting; Fermentation; Hydroge | 2016 |
Molecular hydrogen alleviates motor deficits and muscle degeneration in mdx mice.
Topics: Animals; Blotting, Western; Disease Models, Animal; Dystrophin; Female; Hydrogen; Mice; Mice, Inbred | 2017 |
Hydrogen-rich saline protects against mitochondrial dysfunction and apoptosis in mice with obstructive jaundice.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Blotting, West | 2016 |
Protective Effects of Hydrogen Gas on Experimental Acute Pancreatitis.
Topics: Amylases; Animals; Cell Line; Cell Survival; Ceruletide; Cytokines; Disease Models, Animal; Gene Exp | 2016 |
Hydrogen-rich water improves neurological functional recovery in experimental autoimmune encephalomyelitis mice.
Topics: Analysis of Variance; Animals; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; | 2016 |
Protective effects of hydrogen-rich saline against N-methyl-N-nitrosourea-induced photoreceptor degeneration.
Topics: Analysis of Variance; Animals; Apoptosis; Disease Models, Animal; Electroretinography; Hydrogen; Hyp | 2016 |
Intraperitoneally administered, hydrogen-rich physiologic solution protects against postoperative ileus and is associated with reduced nitric oxide production.
Topics: Animals; Digestive System Surgical Procedures; Disease Models, Animal; Hydrogen; Ileus; Infusions, P | 2016 |
Hydrogen Metabolism in Helicobacter pylori Plays a Role in Gastric Carcinogenesis through Facilitating CagA Translocation.
Topics: Animals; Antigens, Bacterial; Bacterial Proteins; Carcinogenesis; Cell Line; Cell Transformation, Ne | 2016 |
Molecular hydrogen ameliorates several characteristics of preeclampsia in the Reduced Uterine Perfusion Pressure (RUPP) rat model.
Topics: Animals; Blood Pressure; Disease Models, Animal; Female; Fetus; Gene Expression Regulation; Gestatio | 2016 |
Hydrogen does not Exert Neuroprotective Effects or Improve Functional Outcomes in Rats After Intracerebral Hemorrhage.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cerebral Hemorrhage; Deoxyguanosine; Disease Models, Animal; H | 2016 |
Preadministration of Hydrogen-Rich Water Protects Against Lipopolysaccharide-Induced Sepsis and Attenuates Liver Injury.
Topics: Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Hydrogen; In Situ Nick-End | 2017 |
Protective effects of molecular hydrogen on steroid-induced osteonecrosis in rabbits via reducing oxidative stress and apoptosis.
Topics: Angiography; Animals; Antioxidants; Apoptosis; Cholesterol; Disease Models, Animal; Glucocorticoids; | 2017 |
Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia-reperfusion injury.
Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Hydrogen; Inhalation; Male; Myocardial Infarcti | 2008 |
Hydrogen therapy reduces apoptosis in neonatal hypoxia-ischemia rat model.
Topics: Animals; Animals, Newborn; Apoptosis; Caspase 12; Caspase 3; Cell Count; Cerebral Cortex; Disease Mo | 2008 |
Consumption of hydrogen water prevents atherosclerosis in apolipoprotein E knockout mice.
Topics: Animals; Antioxidants; Aorta; Apolipoproteins E; Atherosclerosis; Disease Models, Animal; Drinking; | 2008 |
Chlamydomonas: a sexually active, light-harvesting, carbon-reducing, hydrogen-belching 'planimal'. Conference on the Cell & Molecular Biology of Chlamydomonas.
Topics: Animals; Bioelectric Energy Sources; Carbon; Chlamydomonas; Chloroplasts; Disease Models, Animal; Ge | 2008 |
Neuroprotective effects of hydrogen saline in neonatal hypoxia-ischemia rat model.
Topics: Animals; Animals, Newborn; Body Weight; Brain; Calcium-Binding Proteins; Caspase 3; Cell Death; Dise | 2009 |
Hydrogen gas is ineffective in moderate and severe neonatal hypoxia-ischemia rat models.
Topics: Analysis of Variance; Animals; Animals, Newborn; Body Weight; Brain; Disease Models, Animal; Hydroge | 2009 |
Molecular hydrogen is protective against 6-hydroxydopamine-induced nigrostriatal degeneration in a rat model of Parkinson's disease.
Topics: Administration, Oral; Adrenergic Agents; Animals; Corpus Striatum; Disease Models, Animal; Dopamine; | 2009 |
Hydrogen mediates suppression of colon inflammation induced by dextran sodium sulfate.
Topics: Administration, Inhalation; Animals; Antioxidants; Colitis; Colon; Cytokines; Dextran Sulfate; Disea | 2009 |
Hydrogen from intestinal bacteria is protective for Concanavalin A-induced hepatitis.
Topics: Animals; Biomarkers; Chemical and Drug Induced Liver Injury; Concanavalin A; Disease Models, Animal; | 2009 |
Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Disease Models, Animal; Dopamine; Hydrogen; L | 2009 |
Protection of the retina by rapid diffusion of hydrogen: administration of hydrogen-loaded eye drops in retinal ischemia-reperfusion injury.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Animals; Apoptosis; Biomarkers; Deoxyguanosine; Diffusion; D | 2010 |
Hydrogen-rich saline ameliorates the severity of l-arginine-induced acute pancreatitis in rats.
Topics: Animals; Apoptosis; Arginine; Cell Proliferation; Disease Models, Animal; Hydrogen; Pancreas; Pancre | 2010 |
Hydrogen-rich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer's disease by reduction of oxidative stress.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Disease Models, Animal; Encephalitis; Free | 2010 |
Hydrogen-rich saline protects against liver injury in rats with obstructive jaundice.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; | 2010 |
Experimental verification of protective effect of hydrogen-rich water against cisplatin-induced nephrotoxicity in rats using dynamic contrast-enhanced CT.
Topics: Animals; Antineoplastic Agents; Case-Control Studies; Cisplatin; Contrast Media; Creatinine; Disease | 2010 |
Evaluation of cerebral metabolism by ¹H-magnetic resonance spectroscopy for 4°C saline-induced therapeutic hypothermia in pig model of cardiac arrest.
Topics: Animals; Brain; Cardiac Output; Disease Models, Animal; Female; Heart Arrest; Heart Rate; Hemodynami | 2011 |
Hydrogen is neuroprotective and preserves cerebrovascular reactivity in asphyxiated newborn pigs.
Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Blood Chemical Analysis; Brain; Cerebrovascular Circ | 2010 |
Anti-inflammatory effect of hydrogen-rich saline in a rat model of regional myocardial ischemia and reperfusion.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cardiotonic Agents; Disease Models, Animal; Hydrog | 2011 |
[Effects of hydrogen gas inhalation on serum high mobility group box 1 levels in severe septic mice].
Topics: Administration, Inhalation; Animals; Disease Models, Animal; HMGB1 Protein; Hydrogen; Male; Mice; Mi | 2010 |
The protective role of hydrogen-rich saline in experimental liver injury in mice.
Topics: Animals; Antioxidants; Apoptosis; Cell Proliferation; Chemical and Drug Induced Liver Injury; Diseas | 2011 |
[Effect of hydrogen-rich saline on blood pressure and antioxidant ability of lung tissue in scalded rats following delayed resuscitation].
Topics: Animals; Antioxidants; Blood Pressure; Burns; Disease Models, Animal; Hydrogen; Lung; Male; Rats; Ra | 2010 |
Hydrogen-rich saline reduces oxidative stress and inflammation by inhibit of JNK and NF-κB activation in a rat model of amyloid-beta-induced Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Disease Models, Animal; Enzyme Activation; | 2011 |
Hydrogen-rich saline protects against renal ischemia/reperfusion injury in rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cytokines; Deoxyguanosine; Disease Models, Animal; Hydrogen; K | 2011 |
Inhalation of hydrogen gas attenuates left ventricular remodeling induced by intermittent hypoxia in mice.
Topics: Administration, Inhalation; Aldehydes; Analysis of Variance; Animals; Cholesterol, LDL; Cholesterol, | 2011 |
Hydrogen supplemented air inhalation reduces changes of prooxidant enzyme and gap junction protein levels after transient global cerebral ischemia in the rat hippocampus.
Topics: Administration, Inhalation; Analysis of Variance; Animals; Blood Pressure; Brain Ischemia; Connexins | 2011 |
Hydrogen inhalation is neuroprotective and improves functional outcomes in mice after intracerebral hemorrhage.
Topics: Administration, Inhalation; Analysis of Variance; Animals; Brain; Brain Edema; Cerebral Hemorrhage; | 2011 |
Protective effect of hydrogen gas therapy after germinal matrix hemorrhage in neonatal rats.
Topics: Analysis of Variance; Animals; Animals, Newborn; Cerebral Hemorrhage; Cognition Disorders; Collagena | 2011 |
Protective effects of hydrogen-rich saline in preeclampsia rat model.
Topics: Animals; Antioxidants; Disease Models, Animal; Female; Fetal Resorption; Hydrogen; Interleukin-1beta | 2011 |
Inhalation of hydrogen gas attenuates cisplatin-induced ototoxicity via reducing oxidative stress.
Topics: Administration, Inhalation; Analysis of Variance; Animals; Cisplatin; Disease Models, Animal; Evoked | 2012 |
Hydrogen-rich water attenuates experimental periodontitis in a rat model.
Topics: Animals; Disease Models, Animal; Free Radical Scavengers; Gingiva; Hydrogen; Male; Oxidative Stress; | 2011 |
Hydrogen-rich saline prevents neointima formation after carotid balloon injury by suppressing ROS and the TNF-α/NF-κB pathway.
Topics: Angioplasty, Balloon; Animals; Antioxidants; Becaplermin; Carotid Arteries; Carotid Artery Injuries; | 2012 |
Hydrogen saline treatment attenuates hyperoxia-induced retinopathy by inhibition of oxidative stress and reduction of VEGF expression.
Topics: Animals; Antioxidants; Disease Models, Animal; Hydrogen; Hyperoxia; Malondialdehyde; Mice; Oxidative | 2012 |
Hydrogen decreases athero-susceptibility in apolipoprotein B-containing lipoproteins and aorta of apolipoprotein E knockout mice.
Topics: Animals; Antioxidants; Aorta; Aortic Diseases; Apolipoprotein B-100; Apolipoproteins B; Apolipoprote | 2012 |
Inhalation of hydrogen gas protects against myocardial stunning and infarction in swine.
Topics: Administration, Inhalation; Animals; Cardiotonic Agents; Disease Models, Animal; Female; Gases; Hydr | 2012 |
Oral intake of hydrogen-rich water inhibits intimal hyperplasia in arterialized vein grafts in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Antioxidants; Aorta, Abdominal; Cardiovascu | 2012 |
Inhalation of hydrogen gas attenuates cognitive impairment in transient cerebral ischemia via inhibition of oxidative stress.
Topics: Animals; Antioxidants; CA1 Region, Hippocampal; Cognition Disorders; Disease Models, Animal; Hydroge | 2012 |
Hydrogen-rich saline alleviates experimental noise-induced hearing loss in guinea pigs.
Topics: Animals; Antioxidants; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Female; Guin | 2012 |
Protective effects of hydrogen-rich saline in a rat model of traumatic brain injury via reducing oxidative stress.
Topics: Animals; Antioxidants; Blood-Brain Barrier; Brain Edema; Brain Injuries; Disease Models, Animal; Hyd | 2012 |
Hydrogen-rich saline reverses oxidative stress, cognitive impairment, and mortality in rats submitted to sepsis by cecal ligation and puncture.
Topics: Animals; Caspase 3; Cecum; Cognition Disorders; Disease Models, Animal; Hippocampus; Hydrogen; Ligat | 2012 |
Inhaled hydrogen gas therapy for prevention of testicular ischemia/reperfusion injury in rats.
Topics: Administration, Inhalation; Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Biomarkers | 2012 |
Hydrogen-rich saline alleviates early brain injury via reducing oxidative stress and brain edema following experimental subarachnoid hemorrhage in rabbits.
Topics: Analysis of Variance; Animals; Brain Edema; Brain Injuries; Caspase 12; Caspase 3; Cell Death; Cereb | 2012 |
Beneficial effect of hydrogen-rich saline on cerebral vasospasm after experimental subarachnoid hemorrhage in rats.
Topics: Animals; Antioxidants; Disease Models, Animal; Electrophoretic Mobility Shift Assay; Enzyme-Linked I | 2012 |
Hydrogen-rich water prevents lipid deposition in the descending aorta in a rat periodontitis model.
Topics: Animals; Aorta, Thoracic; Aortic Diseases; Atherosclerosis; Disease Models, Animal; Enzyme-Linked Im | 2012 |
Treatment of hydrogen molecule abates oxidative stress and alleviates bone loss induced by modeled microgravity in rats.
Topics: Animals; Antioxidants; Bone Density; Bone Density Conservation Agents; Cell Differentiation; Cells, | 2013 |
Hydrogen-rich saline reduces the oxidative stress and relieves the severity of trauma-induced acute pancreatitis in rats.
Topics: Amylases; Animals; Chi-Square Distribution; Cytokines; Disease Models, Animal; Hydrogen; Injections, | 2012 |
Effects of hydrogen-rich saline on rats with acute carbon monoxide poisoning.
Topics: Animals; Antioxidants; Brain Chemistry; Brain Injuries; Carbon Monoxide Poisoning; Cognition; Copper | 2013 |
Protective effects of hydrogen-rich saline in a rat model of permanent focal cerebral ischemia via reducing oxidative stress and inflammatory cytokines.
Topics: Animals; Brain Ischemia; Cytokines; Disease Models, Animal; Hydrogen; Inflammation Mediators; Male; | 2012 |
Insufflation of hydrogen gas restrains the inflammatory response of cardiopulmonary bypass in a rat model.
Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Cardiopulmonary Bypass; Cytokines; Disease Models, An | 2013 |
Combination therapy with molecular hydrogen and hyperoxia in a murine model of polymicrobial sepsis.
Topics: Alanine Transaminase; Animals; Catalase; Coinfection; Cytokines; Dinoprost; Disease Models, Animal; | 2012 |
Protective effects of hydrogen-rich saline against erectile dysfunction in a streptozotocin induced diabetic rat model.
Topics: Analysis of Variance; Animals; Blood Glucose; Blotting, Western; Diabetes Mellitus, Experimental; Di | 2013 |
Coadministration of hydrogen gas as part of the carrier gas mixture suppresses neuronal apoptosis and subsequent behavioral deficits caused by neonatal exposure to sevoflurane in mice.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Behavior, Animal; Blotting, Western; | 2013 |
Hydrogen protects rats from dermatitis caused by local radiation.
Topics: Animals; Apoptosis; Cell Survival; Cells, Cultured; Disease Models, Animal; Head; Humans; Hydrogen; | 2014 |
Hydrogen improves glycemic control in type1 diabetic animal model by promoting glucose uptake into skeletal muscle.
Topics: AMP-Activated Protein Kinase Kinases; Animals; Blood Glucose; Cricetinae; Diabetes Mellitus, Experim | 2013 |
Combined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury.
Topics: Acute Lung Injury; Administration, Inhalation; Amine Oxidase (Copper-Containing); Animals; Combined | 2013 |
Hydrogen inhalation ameliorated mast cell-mediated brain injury after intracerebral hemorrhage in mice.
Topics: Administration, Inhalation; Analysis of Variance; Animals; Blood-Brain Barrier; Blotting, Western; B | 2013 |
NOS and COX isoforms and abnormal microvessel responses to CO2 and H+ in hyperoxia-injured lungs.
Topics: Acidosis, Respiratory; Animals; Carbon Dioxide; Disease Models, Animal; Hydrogen; Hypercapnia; Hyper | 2002 |
Angiotensin converting enzyme inhibition partially prevents deficits in water maze performance, hippocampal synaptic plasticity and cerebral blood flow in streptozotocin-diabetic rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Behavior, Animal; Blood Glucose; Cerebral Cortex; | 2003 |
A newborn piglet study of moderate hypoxic-ischemic brain injury by 1H-MRS and MRI.
Topics: Animals; Animals, Newborn; Aspartic Acid; Basal Ganglia; Cerebral Cortex; Cerebrovascular Circulatio | 2004 |
Relationships between astrogliosis and 1H MR spectroscopic measures of brain choline/creatine and myo-inositol/creatine in a primate model.
Topics: Animals; Choline; Creatine; Disease Models, Animal; Glial Fibrillary Acidic Protein; Gliosis; Hydrog | 2005 |
Tissue plasminogen activator promotes matrix metalloproteinase-9 upregulation after focal cerebral ischemia.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Infarction; Brain Ischemia; Disease Models, Animal; Edema | 2005 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma | 2007 |
The hydrogen highway to reperfusion therapy.
Topics: Animals; Antioxidants; Cells, Cultured; Disease Models, Animal; Humans; Hydrogen; Membrane Potential | 2007 |
Recently published papers: more about EGDT, experimental therapies and some inconvenient truths.
Topics: Animals; Critical Care; Cytochromes c; Disease Models, Animal; Education, Medical; Humans; Hydrogen; | 2007 |
1H NMR-based metabolomic identification of at-risk areas after myocardial infarction in swine.
Topics: Animals; Disease Models, Animal; Hydrogen; Lipid Metabolism; Magnetic Resonance Spectroscopy; Metabo | 2007 |
Role of Na(+)-H+ exchange on reperfusion related myocardial injury and arrhythmias in an open-chest swine model.
Topics: Action Potentials; Amiloride; Animals; Arrhythmias, Cardiac; Calcium; Cardiac Pacing, Artificial; Co | 1996 |
Clostridial pathogenicity in experimental necrotising enterocolitis in gnotobiotic quails and protective role of bifidobacteria.
Topics: Animals; Bifidobacterium; Butyric Acid; Cecum; Clostridioides difficile; Clostridium; Clostridium pe | 1998 |
In vivo image-guided (1)H-magnetic resonance spectroscopy of the serial development of hepatocarcinogenesis in an experimental animal model.
Topics: Animals; Disease Models, Animal; Hydrogen; Lipids; Liver; Liver Neoplasms; Magnetic Resonance Imagin | 2001 |
Myocardial blood flow, metabolism, and function with repeated brief coronary occlusions in conscious ponies.
Topics: Animals; Consciousness; Coronary Circulation; Coronary Disease; Disease Models, Animal; Hemodynamics | 1991 |
[Regional cerebral blood flow during development of limbic seizures induced by kainic acid (KA) microinjection into unilateral amygdala in chronic cats].
Topics: Amygdala; Animals; Astrocytes; Cats; Cell Division; Cerebrovascular Circulation; Chronic Disease; Di | 1988 |
Metabolic studies using localized magnetic resonance spectroscopy.
Topics: Animals; Cerebrovascular Disorders; Disease Models, Animal; Energy Metabolism; Humans; Hydrogen; Mag | 1988 |
The role of intraluminal tension and pH in the development of necrotizing enterocolitis: an animal model.
Topics: Animals; Carbohydrate Metabolism; Colon; Disease Models, Animal; Enterocolitis, Pseudomembranous; Hy | 1987 |