Page last updated: 2024-10-18

hydrogen and Degenerative Diseases, Central Nervous System

hydrogen has been researched along with Degenerative Diseases, Central Nervous System in 13 studies

Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.

Research Excerpts

ExcerptRelevanceReference
"Hydrogen-rich water has a significant protective effect on OGD/R-causing HT22 cell injury, and the mechanism may be related to the inhibition of autophagy."4.40Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. ( , 2023)
" First, no dose-response effect is observed."2.48Molecular hydrogen as an emerging therapeutic medical gas for neurodegenerative and other diseases. ( Ichihara, M; Ito, M; Ohno, K, 2012)
"Hydrogen Therapy (HT) has gained scientists' attention with the proven clinical ability to attenuate chronic inflammation, diminish oxidative stress, restrict apoptosis, minimize cellular injury, and refine tissue functioning."1.72Narrative on Hydrogen Therapy and its Clinical Applications: Safety and Efficacy. ( Ahmad, A; Ahmed, N; Baig, AA; Bilal, M; Chopra, H; Hassan, M; Hussain, M; Kamal, MA; Khaliq, M; Putnala, SK; Rachamalla, M; Saeed, MU; Tahir, Z, 2022)
" Here, we show that drinking H(2)-containing water significantly reduced the loss of dopaminergic neurons in PD model mice using both acute and chronic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)."1.35Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. ( Fujita, K; Katafuchi, T; Kido, MA; Nakabeppu, Y; Noda, M; Ohno, M; Sakumi, K; Seike, T; Takaki, A; Tanaka, Y; Yamada, H; Yamaguchi, H; Yamakawa, Y; Yutsudo, N, 2009)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's2 (15.38)29.6817
2010's4 (30.77)24.3611
2020's6 (46.15)2.80

Authors

AuthorsStudies
Fu, Z1
Zhang, J1
Zhang, Y1
Ahmad, A1
Baig, AA1
Hussain, M1
Saeed, MU1
Bilal, M1
Ahmed, N1
Chopra, H1
Hassan, M1
Rachamalla, M1
Putnala, SK1
Khaliq, M1
Tahir, Z1
Kamal, MA1
Qi, B1
Song, Y1
Chen, C1
Zhao, L1
Ma, W1
Meng, S1
Zhuang, X1
Lin, H1
Liang, J1
Cui, Y1
Xie, K1
Chow, V1
Wolf, E1
Lento, C1
Wilson, DJ1
Noda, M3
Liu, J1
Long, J1
Nishimaki, K1
Asada, T1
Ohsawa, I1
Nakajima, E1
Ikejima, C1
Yokota, T1
Kamimura, N1
Ohta, S2
Uemura, Y1
Yoshii, Y1
Horita, T1
Takemi, S1
Sakata, I1
Sakai, T1
Fujita, K1
Seike, T1
Yutsudo, N1
Ohno, M1
Yamada, H1
Yamaguchi, H1
Sakumi, K1
Yamakawa, Y1
Kido, MA1
Takaki, A1
Katafuchi, T1
Tanaka, Y1
Nakabeppu, Y1
Ohno, K1
Ito, M2
Ichihara, M1
Buck, HM1
Terakawa, H1
Abe, K1
Watanabe, Y1
Nakamura, M1
Fujita, N1
Hirabuki, N1
Yanagihara, T1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT02830854]Phase 313 participants (Actual)Interventional2016-07-31Completed
[NCT01759498]Phase 236 participants (Actual)Interventional2012-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for hydrogen and Degenerative Diseases, Central Nervous System

ArticleYear
Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Antioxidants; Cellular Senescence; Humans; Hydrogen; Neurodegenerative Diseases

2022
Developments in rapid hydrogen-deuterium exchange methods.
    Essays in biochemistry, 2023, 03-29, Volume: 67, Issue:2

    Topics: Deuterium; Deuterium Exchange Measurement; Humans; Hydrogen; Intrinsically Disordered Proteins; Neur

2023
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Circulating messenger for neuroprotection induced by molecular hydrogen.
    Canadian journal of physiology and pharmacology, 2019, Volume: 97, Issue:10

    Topics: Animals; Blood-Brain Barrier; Disease Models, Animal; Drinking; Gastric Mucosa; Ghrelin; Humans; Hyd

2019
[Initiation, development and potential of hydrogen medicine: Toward therapeutic and preventive applications of molecular hydrogen against a variety of diseases].
    Seikagaku. The Journal of Japanese Biochemical Society, 2015, Volume: 87, Issue:1

    Topics: Animals; Antioxidants; Gene Expression; Humans; Hydrogen; Neurodegenerative Diseases; Oxidative Stre

2015
Molecular hydrogen as an emerging therapeutic medical gas for neurodegenerative and other diseases.
    Oxidative medicine and cellular longevity, 2012, Volume: 2012

    Topics: Animals; Brain Diseases; Disease Models, Animal; Gases; Humans; Hydrogen; Metabolic Diseases; Neurod

2012
Molecular hydrogen as an emerging therapeutic medical gas for neurodegenerative and other diseases.
    Oxidative medicine and cellular longevity, 2012, Volume: 2012

    Topics: Animals; Brain Diseases; Disease Models, Animal; Gases; Humans; Hydrogen; Metabolic Diseases; Neurod

2012
Molecular hydrogen as an emerging therapeutic medical gas for neurodegenerative and other diseases.
    Oxidative medicine and cellular longevity, 2012, Volume: 2012

    Topics: Animals; Brain Diseases; Disease Models, Animal; Gases; Humans; Hydrogen; Metabolic Diseases; Neurod

2012
Molecular hydrogen as an emerging therapeutic medical gas for neurodegenerative and other diseases.
    Oxidative medicine and cellular longevity, 2012, Volume: 2012

    Topics: Animals; Brain Diseases; Disease Models, Animal; Gases; Humans; Hydrogen; Metabolic Diseases; Neurod

2012

Trials

2 trials available for hydrogen and Degenerative Diseases, Central Nervous System

ArticleYear
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19.
    Science & sports, 2023, Apr-04

    Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosp

2023
Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment.
    Current Alzheimer research, 2018, 03-14, Volume: 15, Issue:5

    Topics: Administration, Oral; Aged; Aldehyde Dehydrogenase, Mitochondrial; Animals; Antioxidants; Apolipopro

2018

Other Studies

6 other studies available for hydrogen and Degenerative Diseases, Central Nervous System

ArticleYear
Narrative on Hydrogen Therapy and its Clinical Applications: Safety and Efficacy.
    Current pharmaceutical design, 2022, Volume: 28, Issue:31

    Topics: Apoptosis; Humans; Hydrogen; Inflammation; Neurodegenerative Diseases; Oxidative Stress

2022
Molecular hydrogen attenuates sepsis-induced cognitive dysfunction through regulation of tau phosphorylation.
    International immunopharmacology, 2023, Volume: 114

    Topics: Animals; Cognitive Dysfunction; Hippocampus; Hydrogen; Male; Mice; Mice, Inbred C57BL; Neurodegenera

2023
Neuroprotective and Preventative Effects of Molecular Hydrogen.
    Current pharmaceutical design, 2021, Volume: 27, Issue:5

    Topics: Animals; Female; Hydrogen; Mice; Neurodegenerative Diseases; Neuroprotection; Neuroprotective Agents

2021
Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.
    PloS one, 2009, Sep-30, Volume: 4, Issue:9

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Disease Models, Animal; Dopamine; Hydrogen; L

2009
The role of the carboxamide group in nicotinamide adenine dinucleotide in relation to hydride transfer: the reduced form of the dinucleotide as remedy in the modulation of neurotransmission.
    Nucleosides, nucleotides & nucleic acids, 2005, Volume: 24, Issue:5-7

    Topics: Adenine Nucleotides; Amides; Animals; Carbon; Dinucleoside Phosphates; Humans; Hydrogen; Kinetics; M

2005
Proton magnetic resonance spectroscopy (1H MRS) in patients with sporadic cerebellar degeneration.
    Journal of neuroimaging : official journal of the American Society of Neuroimaging, 1999, Volume: 9, Issue:2

    Topics: Adult; Aged; Aspartic Acid; Atrophy; Cerebellar Diseases; Cerebellum; Choline; Creatine; Disease Pro

1999