Page last updated: 2024-10-18

hydrogen and Colonic Diseases, Functional

hydrogen has been researched along with Colonic Diseases, Functional in 29 studies

Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.

Colonic Diseases, Functional: Chronic or recurrent colonic disorders without an identifiable structural or biochemical explanation. The widely recognized IRRITABLE BOWEL SYNDROME falls into this category.

Research Excerpts

ExcerptRelevanceReference
"Fifty-three adults (12 males, 41 females), who were identified as fructose malabsorbers according to their breath-H2 concentrations, filled out a Beck's depression inventory-questionnaire, and a questionnaire with arbitrary scales for measurement of meteorism, stool frequency and quality of life for a 4-week period before dietary intervention and 4 weeks after dietary change as for fructose- and sorbitol-reduced diet."5.09Fructose- and sorbitol-reduced diet improves mood and gastrointestinal disturbances in fructose malabsorbers. ( Bair, H; Fuchs, D; Ledochowski, M; Probst, T; Widner, B, 2000)
"Lactose malabsorption was diagnosed in 157 patients (68."2.68Lactose malabsorption and irritable bowel syndrome. Effect of a long-term lactose-free diet. ( Bilotta, T; Frandina, C; Frieri, G; Ricciardi, MR; Vernia, P, 1995)
"Lactose intolerance affects millions of people world-wide and should be suspected specially when evaluating gastrointestinal symptoms in ethnic populations in which it is prevalent."2.41[Lactose and gluten intolerance: which to suscept?]. ( Codden, T; Colonius, V; Mascart, F; Rickaert, F; Van Gossum, M, 2000)
"Lactose malabsorption was studied, by hydrogen breath test, in 72 adults suffering from irritable bowel syndrome, in 20 ulcerative colitis patients, and in 69 healthy subjects."1.27Hydrogen breath test quantification and clinical correlation of lactose malabsorption in adult irritable bowel syndrome and ulcerative colitis. ( Garuti, G; Giacobazzi, G; Malaguti, P; Sciarretta, G; Verri, A; Zanirato, P, 1984)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199012 (41.38)18.7374
1990's10 (34.48)18.2507
2000's6 (20.69)29.6817
2010's1 (3.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Madrid, AM1
Landskron, G1
Klapp, G1
Reyes, A1
Pizarro, C1
Defilippi, C1
Sen, S2
Dear, KL1
King, TS2
Elia, M2
Hunter, JO4
Cash, BD1
Schoenfeld, P1
Chey, WD1
Mullan, MM1
Parker, TJ1
Woolner, JT1
Tarry, SA1
Gaby, AR1
Newcomer, AD2
Park, HS1
O'Brien, PC1
McGill, DB2
Kneepkens, CM1
Vonk, RJ1
Fernandes, J1
Sciarretta, G1
Giacobazzi, G1
Verri, A1
Zanirato, P1
Garuti, G1
Malaguti, P1
Read, NW3
Corbett, CL1
Thomas, S1
Hobson, N1
Bergman, I1
Holdsworth, CD1
Vernia, P1
Ricciardi, MR1
Frandina, C1
Bilotta, T1
Frieri, G1
Casellas, F2
Malagelada, JR2
Schöfl, R1
Ferenci, P1
Vogelsang, H1
Gangl, A1
Chicharro, L1
Tuffnell, Q1
Lee, AJ1
Van Gossum, M1
Mascart, F1
Rickaert, F1
Codden, T1
Colonius, V1
Ledochowski, M1
Widner, B1
Bair, H1
Probst, T1
Fuchs, D1
Symons, P1
Jones, MP1
Kellow, JE1
Lembcke, B1
Bornholdt, C1
Kirchhoff, S1
Lankisch, PG1
Nelis, GF1
Vermeeren, MA1
Jansen, W1
Enck, P1
Kremer, A1
Kuhlbusch, R1
Niederau, C1
Erckenbrecht, JF1
Berges, W1
Haderstorfer, B1
Psycholgin, D1
Whitehead, WE1
Schuster, MM1
Littman, A1
Afdhal, NH1
Piggott, C1
Long, AA1
O'Donoghue, DP1
Filali, A1
Ben Amor, A1
Ouertani, J1
Ben Abdallah, M1
Garoui, H1
Al-Janabi, MN1
Bates, TE1
Holgate, AM1
Cann, PA1
Kinsman, RI1
McFarlane, A1
Brown, C1
Jain, NK1
Rosenberg, DB1
Ulahannan, MJ1
Glasser, MJ1
Pitchumoni, CS1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Role of Irritable Bowel Syndrome in Lactose Intolerance (LION Trial): Protocol of a Multicentre Randomized Controlled Clinical Trial[NCT05100719]200 participants (Anticipated)Interventional2022-09-30Not yet recruiting
Effect of an Enriched Butyrogenic Fibres Diet on Rectal Sensitivity in Healthy Control and IBS Patients.[NCT00314886]15 participants (Anticipated)Interventional2005-01-31Recruiting
The Use of VSL#3 in Irritable Bowel Syndrome in Children[NCT00932841]Phase 115 participants (Actual)Interventional2008-01-31Terminated (stopped due to PI has re-located. PI terminated FDA IND # and closed study.)
Fructose and Fructans and Irritable Bowel Syndrome: MRI Study of Underlying Mechanisms[NCT01776853]69 participants (Actual)Interventional2013-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for hydrogen and Colonic Diseases, Functional

ArticleYear
The utility of diagnostic tests in irritable bowel syndrome patients: a systematic review.
    The American journal of gastroenterology, 2002, Volume: 97, Issue:11

    Topics: Autoantibodies; Blood Cell Count; Breath Tests; Colonic Diseases, Functional; Databases, Bibliograph

2002
[Lactose and gluten intolerance: which to suscept?].
    Revue medicale de Bruxelles, 2000, Volume: 21, Issue:4

    Topics: Barium Sulfate; Biopsy; Breath Tests; Celiac Disease; Colonic Diseases, Functional; Contrast Media;

2000

Trials

6 trials available for hydrogen and Colonic Diseases, Functional

ArticleYear
Effect of Lactobacillus plantarum 299v on colonic fermentation and symptoms of irritable bowel syndrome.
    Digestive diseases and sciences, 2002, Volume: 47, Issue:11

    Topics: Adult; Avena; Breath Tests; Calorimetry, Indirect; Colon; Colonic Diseases, Functional; Cross-Over S

2002
Response of patients with irritable bowel syndrome and lactase deficiency using unfermented acidophilus milk.
    The American journal of clinical nutrition, 1983, Volume: 38, Issue:2

    Topics: Adolescent; Adult; Aged; Animals; Breath Tests; Clinical Trials as Topic; Colonic Diseases, Function

1983
Lactose malabsorption and irritable bowel syndrome. Effect of a long-term lactose-free diet.
    The Italian journal of gastroenterology, 1995, Volume: 27, Issue:3

    Topics: Adult; Breath Tests; Chi-Square Distribution; Colonic Diseases, Functional; Diet; Female; Humans; Hy

1995
Abnormal colonic fermentation in irritable bowel syndrome.
    Lancet (London, England), 1998, Oct-10, Volume: 352, Issue:9135

    Topics: Adult; Breath Tests; Colon; Colonic Diseases, Functional; Cross-Over Studies; Feces; Female; Ferment

1998
Abnormal colonic fermentation in irritable bowel syndrome.
    Lancet (London, England), 1998, Oct-10, Volume: 352, Issue:9135

    Topics: Adult; Breath Tests; Colon; Colonic Diseases, Functional; Cross-Over Studies; Feces; Female; Ferment

1998
Abnormal colonic fermentation in irritable bowel syndrome.
    Lancet (London, England), 1998, Oct-10, Volume: 352, Issue:9135

    Topics: Adult; Breath Tests; Colon; Colonic Diseases, Functional; Cross-Over Studies; Feces; Female; Ferment

1998
Abnormal colonic fermentation in irritable bowel syndrome.
    Lancet (London, England), 1998, Oct-10, Volume: 352, Issue:9135

    Topics: Adult; Breath Tests; Colon; Colonic Diseases, Functional; Cross-Over Studies; Feces; Female; Ferment

1998
Controlled trial of oligofructose in the management of irritable bowel syndrome.
    The Journal of nutrition, 1999, Volume: 129, Issue:7 Suppl

    Topics: Adolescent; Adult; Aged; Breath Tests; Colonic Diseases, Functional; Cross-Over Studies; Double-Blin

1999
Fructose- and sorbitol-reduced diet improves mood and gastrointestinal disturbances in fructose malabsorbers.
    Scandinavian journal of gastroenterology, 2000, Volume: 35, Issue:10

    Topics: Adolescent; Adult; Affect; Aged; Breath Tests; Colonic Diseases, Functional; Depression; Digestive S

2000

Other Studies

21 other studies available for hydrogen and Colonic Diseases, Functional

ArticleYear
Lactulose hydrogen breath test and functional symptoms in pediatric patients.
    Digestive diseases and sciences, 2012, Volume: 57, Issue:5

    Topics: Abdominal Pain; Adolescent; Breath Tests; Child; Child, Preschool; Colonic Diseases, Functional; Fem

2012
Evaluation of hydrogen excretion after lactulose administration as a screening test for causes of irritable bowel syndrome.
    European journal of gastroenterology & hepatology, 2002, Volume: 14, Issue:7

    Topics: Adult; Aged; Breath Tests; Colonic Diseases, Functional; Female; Humans; Hydrogen; Lactulose; Male;

2002
Treatment with enteric-coated peppermint oil reduced small-intestinal bacterial overgrowth in a patient with irritable bowel syndrome.
    Alternative medicine review : a journal of clinical therapeutic, 2003, Volume: 8, Issue:1

    Topics: Anti-Bacterial Agents; Breath Tests; Colonic Diseases, Functional; Humans; Hydrogen; Intestine, Smal

2003
Incomplete intestinal absorption of fructose.
    Archives of disease in childhood, 1984, Volume: 59, Issue:8

    Topics: Adolescent; Biological Transport, Active; Breath Tests; Child; Child, Preschool; Colonic Diseases, F

1984
Hydrogen breath test quantification and clinical correlation of lactose malabsorption in adult irritable bowel syndrome and ulcerative colitis.
    Digestive diseases and sciences, 1984, Volume: 29, Issue:12

    Topics: Adolescent; Adult; Aged; Animals; Breath Tests; Child; Colitis, Ulcerative; Colonic Diseases, Functi

1984
Small bowel transit time of food in man: measurement, regulation and possible importance.
    Scandinavian journal of gastroenterology. Supplement, 1984, Volume: 96

    Topics: Biological Transport, Active; Breath Tests; Carbohydrate Metabolism; Colon; Colonic Diseases, Functi

1984
Irritable bowel syndrome. Role of lactase deficiency.
    Mayo Clinic proceedings, 1983, Volume: 58, Issue:5

    Topics: Adult; Aged; Breath Tests; Colonic Diseases, Functional; Europe; Female; Humans; Hydrogen; Lactose I

1983
Electrochemical detector for breath hydrogen determination: measurement of small bowel transit time in normal subjects and patients with the irritable bowel syndrome.
    Gut, 1981, Volume: 22, Issue:10

    Topics: Adolescent; Adult; Aged; Breath Tests; Colonic Diseases, Functional; Female; Gastrointestinal Motili

1981
Clinical applicability of shortened D-xylose breath test for diagnosis of intestinal malabsorption.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:11

    Topics: Adolescent; Adult; Aged; Breath Tests; Colonic Diseases, Functional; Female; Humans; Hydrogen; Intes

1994
[Effect of a lactose-free diet on irritable bowel syndrome].
    Wiener klinische Wochenschrift, 1993, Volume: 105, Issue:12

    Topics: Adult; Aged; Breath Tests; Colonic Diseases, Functional; Female; Humans; Hydrogen; Lactose; Lactose

1993
Potential usefulness of hydrogen breath test with D-xylose in clinical management of intestinal malabsorption.
    Digestive diseases and sciences, 1993, Volume: 38, Issue:2

    Topics: Adult; Analysis of Variance; Breath Tests; Colonic Diseases, Functional; Female; Humans; Hydrogen; I

1993
Symptom provocation in irritable bowel syndrome. Effects of differing doses of fructose-sorbitol.
    Scandinavian journal of gastroenterology, 1992, Volume: 27, Issue:11

    Topics: Administration, Oral; Adult; Breath Tests; Colonic Diseases, Functional; Dose-Response Relationship,

1992
Clinical evaluation of a 25 g D-xylose hydrogen (H2) breath test.
    Zeitschrift fur Gastroenterologie, 1990, Volume: 28, Issue:10

    Topics: Adult; Aged; Breath Tests; Celiac Disease; Chronic Disease; Colonic Diseases, Functional; Digestive

1990
Role of fructose-sorbitol malabsorption in the irritable bowel syndrome.
    Gastroenterology, 1990, Volume: 99, Issue:4

    Topics: Adult; Breath Tests; Colonic Diseases, Functional; Female; Fructose; Humans; Hydrogen; Intestinal Ab

1990
Prevalence of lactose malabsorption among patients with functional bowel disorders.
    Zeitschrift fur Gastroenterologie, 1990, Volume: 28, Issue:5

    Topics: Breath Tests; Colonic Diseases, Functional; Cross-Sectional Studies; Diagnosis, Differential; Follow

1990
Intestinal gas production from bacterial fermentation of undigested carbohydrate in irritable bowel syndrome.
    The American journal of gastroenterology, 1989, Volume: 84, Issue:4

    Topics: Adult; Breath Tests; Colonic Diseases, Functional; Dietary Carbohydrates; Digestion; Enterobacteriac

1989
Lactase deficiency. Diagnosis and management.
    Hospital practice (Office ed.), 1987, Jan-30, Volume: 22, Issue:1A

    Topics: Adult; beta-Galactosidase; Blood Glucose; Breath Tests; Celiac Disease; Colonic Diseases, Functional

1987
Carbohydrate handling by colonic flora--is it pathogenic in the irritable bowel syndrome?
    Irish journal of medical science, 1986, Volume: 155, Issue:6

    Topics: Adult; Anti-Bacterial Agents; Breath Tests; Carbohydrate Metabolism; Colon; Colonic Diseases, Functi

1986
[The H2-lactulose breath test in the study of functional colonopathies].
    La Tunisie medicale, 1986, Volume: 64, Issue:4

    Topics: Adult; Aged; Breath Tests; Colonic Diseases, Functional; Disaccharides; Evaluation Studies as Topic;

1986
Interpretation of the breath hydrogen profile obtained after ingesting a solid meal containing unabsorbable carbohydrate.
    Gut, 1985, Volume: 26, Issue:8

    Topics: Absorption; Adult; Aged; Breath Tests; Colon; Colonic Diseases, Functional; Dietary Carbohydrates; F

1985
Sorbitol intolerance in adults.
    The American journal of gastroenterology, 1985, Volume: 80, Issue:9

    Topics: Abdomen; Adult; Black People; Breath Tests; Colonic Diseases, Functional; Diagnosis, Differential; D

1985