Page last updated: 2024-10-18

hydrogen and Cerebral Infarction

hydrogen has been researched along with Cerebral Infarction in 11 studies

Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.

Cerebral Infarction: The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study was to test the hypothesis that the efficacy of 7-nitroindazole (7-NI), a selective neuronal nitric oxide (NO) synthase (NOS) inhibitor, is pH dependent in vivo during focal cerebral ischemia."3.72Is neuroprotective efficacy of nNOS inhibitor 7-NI dependent on ischemic intracellular pH? ( Anderson, RE; Coert, BA; Meyer, FB, 2003)
" First, in patients with cerebral infarctions, increased concentrations of lactate were found in the majority of patients, and N-acetyl aspartate (NAA) was reduced to a significantly greater extent than choline (Cho) or creatine (Cre)."3.68Proton magnetic resonance spectroscopy of human brain: applications to normal white matter, chronic infarction, and MRI white matter signal hyperintensities. ( Calabrese, G; Deicken, R; Fein, G; Fisher, SN; Hetherington, HP; Sappey-Marinier, D; Van Dyke, C; Weiner, MW, 1992)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (54.55)18.2507
2000's4 (36.36)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ono, H1
Nishijima, Y1
Ohta, S3
Sakamoto, M1
Kinone, K1
Horikosi, T1
Tamaki, M1
Takeshita, H1
Futatuki, T1
Ohishi, W1
Ishiguro, T1
Okamoto, S1
Ishii, S1
Takanami, H1
Anderson, RE2
Meyer, FB2
Coert, BA1
Ohsawa, I1
Ishikawa, M1
Takahashi, K1
Watanabe, M1
Nishimaki, K1
Yamagata, K1
Katsura, K1
Katayama, Y2
Asoh, S1
Yamamuro, M1
Igarashi, H1
Terashi, A1
Sick, TJ1
Tang, R1
Pérez-Pinzón, MA1
Wang, Z1
Bogdan, AR1
Zimmerman, RA1
Gusnard, DA1
Leigh, JS1
Ohene-Frempong, K1
Hugg, JW1
Duijn, JH1
Matson, GB1
Maudsley, AA1
Tsuruda, JS1
Gelinas, DF1
Weiner, MW2
Sappey-Marinier, D1
Calabrese, G1
Hetherington, HP1
Fisher, SN1
Deicken, R1
Van Dyke, C1
Fein, G1
Houkin, K1
Matsuzawa, H1
Miyasaka, K1
Kamiyama, H1
Iwasaki, Y1
Abe, H1
Hida, K1
Koiwa, M1
Kashiwaba, T1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Perioperative Hydrogen Inhalation on Post-operative Pain and Inflammation Cytokines[NCT05476575]32 participants (Anticipated)Interventional2021-10-28Recruiting
Efficacy and Safety of Hydrogen Inhalation on Bronchiectasis (HYBRID): A Randomized, Multi-center, Double-blind, Parallel-group Study[NCT02765295]120 participants (Anticipated)Interventional2016-06-01Recruiting
Evaluation of the Daily Intake of 0.5 L of Water Saturated With Molecular Hydrogen for 21 Days in COVID-19 Patients Treated in Ambulatory Care. Double-blind, Randomized, Comparative Study[NCT04716985]700 participants (Actual)Interventional2021-01-22Active, not recruiting
Adjuvant Therapy for Severe COPD Patients in the Stable Phase by an Oxyhydrogen Generator With Nebulizer: A Multi-centric, Randomized, Parallel-control and Double-blinded Clinic Study[NCT02850185]170 participants (Anticipated)Interventional2016-07-15Recruiting
Adjuvant Therapy for Severe Asthma by an Oxyhydrogen Generator With Nebulizer: A Multi-centric, Randomized, Parallel-control and Double-blinded Clinic Study on Effectiveness and Safety[NCT02883582]150 participants (Anticipated)Interventional2016-08-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for hydrogen and Cerebral Infarction

ArticleYear
[Hydrogen gas and hydrogen water act as a therapeutic and preventive antioxidant with a novel concept].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 2008, Volume: 45, Issue:4

    Topics: Animals; Antioxidants; Cells, Cultured; Cerebral Infarction; Gases; Hydrogen; Rats; Water

2008

Trials

1 trial available for hydrogen and Cerebral Infarction

ArticleYear
Hydrogen Gas Inhalation Treatment in Acute Cerebral Infarction: A Randomized Controlled Clinical Study on Safety and Neuroprotection.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2017, Volume: 26, Issue:11

    Topics: Administration, Inhalation; Aged; Aged, 80 and over; Blood Pressure; Cerebral Infarction; Diffusion

2017

Other Studies

9 other studies available for hydrogen and Cerebral Infarction

ArticleYear
Protection of focal cerebral ischemia by alkalinization of systemic pH.
    Neurosurgery, 2002, Volume: 51, Issue:5

    Topics: Alkalies; Animals; Brain; Brain Ischemia; Carbonates; Cerebral Cortex; Cerebral Infarction; Cerebrov

2002
Is neuroprotective efficacy of nNOS inhibitor 7-NI dependent on ischemic intracellular pH?
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 284, Issue:1

    Topics: Animals; Brain; Brain Ischemia; Cerebral Infarction; Cerebrovascular Circulation; Enzyme Inhibitors;

2003
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals.
    Nature medicine, 2007, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Antioxidants; Cerebral Infarction; Disease Models, Animal; Huma

2007
[1H and 31P-magnetic resonance spectroscopy of cerebral infarction in rats].
    Nihon Ika Daigaku zasshi, 1997, Volume: 64, Issue:2

    Topics: Animals; Brain; Brain Chemistry; Cerebral Infarction; Hydrogen; Magnetic Resonance Spectroscopy; Mal

1997
Cerebral blood flow does not mediate the effect of brain temperature on recovery of extracellular potassium ion activity after transient focal ischemia in the rat.
    Brain research, 1999, Mar-13, Volume: 821, Issue:2

    Topics: Animals; Body Temperature; Brain; Cerebral Infarction; Cerebrovascular Circulation; Cerebrovascular

1999
Investigation of stroke in sickle cell disease by 1H nuclear magnetic resonance spectroscopy.
    Neuroradiology, 1992, Volume: 35, Issue:1

    Topics: Adolescent; Adult; Anemia, Sickle Cell; Aspartic Acid; Atrophy; Brain; Brain Ischemia; Cerebral Infa

1992
Elevated lactate and alkalosis in chronic human brain infarction observed by 1H and 31P MR spectroscopic imaging.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1992, Volume: 12, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Alkalosis; Cerebral Infarction; Female; Humans; Hydrogen; Lactates;

1992
Proton magnetic resonance spectroscopy of human brain: applications to normal white matter, chronic infarction, and MRI white matter signal hyperintensities.
    Magnetic resonance in medicine, 1992, Volume: 26, Issue:2

    Topics: Aged; Aged, 80 and over; Aspartic Acid; Brain; Brain Chemistry; Brain Ischemia; Cerebral Infarction;

1992
[Longitudinal change of H-1 spectroscopy in cerebral infarction].
    No to shinkei = Brain and nerve, 1991, Volume: 43, Issue:6

    Topics: Aged; Aspartic Acid; Brain; Cerebral Infarction; Female; Humans; Hydrogen; Lactates; Lactic Acid; Ma

1991