Page last updated: 2024-10-18

hydrogen and Cerebral Hemorrhage

hydrogen has been researched along with Cerebral Hemorrhage in 10 studies

Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.

Cerebral Hemorrhage: Bleeding into one or both CEREBRAL HEMISPHERES including the BASAL GANGLIA and the CEREBRAL CORTEX. It is often associated with HYPERTENSION and CRANIOCEREBRAL TRAUMA.

Research Excerpts

ExcerptRelevanceReference
"Hydrogen treatment significantly reduced the level of oxidative stress, neuroinflammation, neuronal damage, and apoptosis-related genes."5.48Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model. ( Choi, KS; Do, SH; Hwang, SJ; Kim, HJ; Yi, HJ, 2018)
"Hydrogen treatment was performed for 3 days."5.43Hydrogen does not Exert Neuroprotective Effects or Improve Functional Outcomes in Rats After Intracerebral Hemorrhage. ( Mori, K; Nagatani, K; Otani, N; Takeuchi, S; Wada, K, 2016)
"Hydrogen treatment diminished phosphorylation of Lyn kinase and release of tryptase, decreased accumulation and degranulation of mast cells, attenuated blood-brain barrier disruption, and improved neurobehavioral function."5.39Hydrogen inhalation ameliorated mast cell-mediated brain injury after intracerebral hemorrhage in mice. ( Lekic, T; Ma, Q; Manaenko, A; Tang, J; Zhang, JH, 2013)
"Hyperglycemia is one of the major factors for hemorrhagic transformation after ischemic stroke."5.36Hydrogen gas reduced acute hyperglycemia-enhanced hemorrhagic transformation in a focal ischemia rat model. ( Chen, CH; Liu, WW; Manaenko, A; Ostrowki, RP; Tang, J; Zhan, Y; Zhang, JH, 2010)
"Hydrogen treatment significantly reduced the level of oxidative stress, neuroinflammation, neuronal damage, and apoptosis-related genes."1.48Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model. ( Choi, KS; Do, SH; Hwang, SJ; Kim, HJ; Yi, HJ, 2018)
"Hydrogen treatment was performed for 3 days."1.43Hydrogen does not Exert Neuroprotective Effects or Improve Functional Outcomes in Rats After Intracerebral Hemorrhage. ( Mori, K; Nagatani, K; Otani, N; Takeuchi, S; Wada, K, 2016)
"Hydrogen treatment diminished phosphorylation of Lyn kinase and release of tryptase, decreased accumulation and degranulation of mast cells, attenuated blood-brain barrier disruption, and improved neurobehavioral function."1.39Hydrogen inhalation ameliorated mast cell-mediated brain injury after intracerebral hemorrhage in mice. ( Lekic, T; Ma, Q; Manaenko, A; Tang, J; Zhang, JH, 2013)
"Hydrogen (H2) is a potent antioxidant shown to selectively reverse cytotoxic oxygen-radical injury in the brain."1.37Protective effect of hydrogen gas therapy after germinal matrix hemorrhage in neonatal rats. ( Fathali, N; Lekic, T; Manaenko, A; Peterson, M; Rolland, W; Tang, J; Zhang, JH, 2011)
"Hyperglycemia is one of the major factors for hemorrhagic transformation after ischemic stroke."1.36Hydrogen gas reduced acute hyperglycemia-enhanced hemorrhagic transformation in a focal ischemia rat model. ( Chen, CH; Liu, WW; Manaenko, A; Ostrowki, RP; Tang, J; Zhan, Y; Zhang, JH, 2010)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's1 (10.00)18.2507
2000's1 (10.00)29.6817
2010's6 (60.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
An, P1
Zhao, XC1
Liu, MJ1
You, YQ1
Li, JY1
Choi, KS1
Kim, HJ1
Do, SH1
Hwang, SJ1
Yi, HJ1
Takeuchi, S1
Nagatani, K1
Otani, N1
Wada, K1
Mori, K1
Chen, CH1
Manaenko, A4
Zhan, Y1
Liu, WW1
Ostrowki, RP1
Tang, J4
Zhang, JH4
Lekic, T3
Ma, Q2
Ostrowski, RP1
Rolland, W1
Fathali, N1
Peterson, M1
COURVILLE, CB1
Richardson, BS1
Wakim, E1
daSilva, O1
Walton, J1
Burtscher, IM1
Ståhlberg, F1
Holtås, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of the Daily Intake of 0.5 L of Water Saturated With Molecular Hydrogen for 21 Days in COVID-19 Patients Treated in Ambulatory Care. Double-blind, Randomized, Comparative Study[NCT04716985]700 participants (Actual)Interventional2021-01-22Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

10 other studies available for hydrogen and Cerebral Hemorrhage

ArticleYear
Gender-based differences in neuroprotective effects of hydrogen gas against intracerebral hemorrhage-induced depression.
    Neurochemistry international, 2022, Volume: 153

    Topics: Animals; Cerebral Hemorrhage; Depression; Disease Models, Animal; Female; Humans; Hydrogen; Male; Mi

2022
Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model.
    Brain research bulletin, 2018, Volume: 142

    Topics: Administration, Inhalation; Animals; Apoptosis; Brain; Cerebral Hemorrhage; Disease Models, Animal;

2018
Hydrogen does not Exert Neuroprotective Effects or Improve Functional Outcomes in Rats After Intracerebral Hemorrhage.
    Turkish neurosurgery, 2016, Volume: 26, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cerebral Hemorrhage; Deoxyguanosine; Disease Models, Animal; H

2016
Hydrogen gas reduced acute hyperglycemia-enhanced hemorrhagic transformation in a focal ischemia rat model.
    Neuroscience, 2010, Aug-11, Volume: 169, Issue:1

    Topics: Administration, Inhalation; Aldehydes; Animals; Antioxidants; Aquaporin 4; Brain Damage, Chronic; Ce

2010
Hydrogen inhalation is neuroprotective and improves functional outcomes in mice after intracerebral hemorrhage.
    Acta neurochirurgica. Supplement, 2011, Volume: 111

    Topics: Administration, Inhalation; Analysis of Variance; Animals; Brain; Brain Edema; Cerebral Hemorrhage;

2011
Protective effect of hydrogen gas therapy after germinal matrix hemorrhage in neonatal rats.
    Acta neurochirurgica. Supplement, 2011, Volume: 111

    Topics: Analysis of Variance; Animals; Animals, Newborn; Cerebral Hemorrhage; Cognition Disorders; Collagena

2011
Hydrogen inhalation ameliorated mast cell-mediated brain injury after intracerebral hemorrhage in mice.
    Critical care medicine, 2013, Volume: 41, Issue:5

    Topics: Administration, Inhalation; Analysis of Variance; Animals; Blood-Brain Barrier; Blotting, Western; B

2013
CONFUSION OF PRESUMED TOXIC GAS POISONING FOR FATAL GRANULOMATOUS MENINGO-ENCIPHALITIS RESULTING IN A SEVERE PROGRESSIVE ARTERITIS AND GROSS CEREBRAL HEMORRHAGES. REPORT OF FATAL CASE ASSESSED AS HYDROGEN PHOSPHIDE (PHOSPHINE) POISONING.
    Bulletin of the Los Angeles Neurological Society, 1964, Volume: 29

    Topics: Arteritis; Autopsy; Brain; Cerebral Hemorrhage; Confusion; Gas Poisoning; Granulomatosis with Polyan

1964
Preterm histologic chorioamnionitis: impact on cord gas and pH values and neonatal outcome.
    American journal of obstetrics and gynecology, 2006, Volume: 195, Issue:5

    Topics: Acidosis; Cerebral Hemorrhage; Cerebral Ventricles; Chorioamnionitis; Female; Fetal Blood; Humans; H

2006
Proton (1H) MR spectroscopy for routine diagnostic evaluation of brain lesions.
    Acta radiologica (Stockholm, Sweden : 1987), 1997, Volume: 38, Issue:6

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Brain Diseases; Brain Neo

1997