Page last updated: 2024-10-18

hydrogen and Cardiovascular Stroke

hydrogen has been researched along with Cardiovascular Stroke in 21 studies

Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.

Research Excerpts

ExcerptRelevanceReference
" Therefore because oxidative stress plays a significant role in the pathophysiology of myocardial infarction (MI), the aim of our study was to investigate whether hydrogen-rich saline has cardioprotective effects against isoproterenol-induced MI in rats."7.81Cardioprotective Effect of Hydrogen-rich Saline on Isoproterenol-induced Myocardial Infarction in Rats. ( Han, JJ; Jing, L; Qin, SC; Sun, XJ; Wang, Y; Zhao, B; Zhao, XM, 2015)
" Therefore because oxidative stress plays a significant role in the pathophysiology of myocardial infarction (MI), the aim of our study was to investigate whether hydrogen-rich saline has cardioprotective effects against isoproterenol-induced MI in rats."3.81Cardioprotective Effect of Hydrogen-rich Saline on Isoproterenol-induced Myocardial Infarction in Rats. ( Han, JJ; Jing, L; Qin, SC; Sun, XJ; Wang, Y; Zhao, B; Zhao, XM, 2015)
"The inhibition of Na(+)-H+ exchange (NHE) with amiloride analogues in vitro has been shown to prevent reperfusion arrhythmias and additional cell necrosis."3.69Role of Na(+)-H+ exchange on reperfusion related myocardial injury and arrhythmias in an open-chest swine model. ( Fukuta, M; Iwa, T; Kobayashi, T; Uesugi, M; Wakida, Y, 1996)
"After acute myocardial infarction (produced by ligation in the dog), the authors marked the borders of infarction with disulphine blue or methylene blue and determined, by means of hydrogen clearance, the blood supply in the centre and at the margin of infarction as well as at different distances from the latter."3.65[Dye-marking and hydrogen clearance in demonstrating acute ischemic myocardial areas]. ( Bretschneider, G; Linke, PG; Neef, H; Pauer, D; Richter, RA, 1975)
"Acute myocardial infarction is associated with an accumulation of lipids."1.28Visualization of altered myocardial lipids by 1H NMR chemical-shift imaging following ischemic insult. ( Bouchard, A; Doyle, M; Evanochko, WT; Pohost, GM; Wilson, R; Wolkowicz, PE, 1991)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19905 (23.81)18.7374
1990's5 (23.81)18.2507
2000's3 (14.29)29.6817
2010's5 (23.81)24.3611
2020's3 (14.29)2.80

Authors

AuthorsStudies
Wang, C1
Li, J1
Kang, M1
Huang, X1
Liu, Y1
Zhou, N1
Zhang, Z1
Nie, C2
Ding, X1
A, R1
Zheng, M1
Li, Z1
Pan, S1
Yang, W2
Yang, H1
Liu, S1
Du, H1
Hong, Z1
Lv, Y1
Gao, Y1
Asanuma, H2
Kitakaze, M2
Shinbo, T1
Kokubo, K1
Sato, Y1
Hagiri, S1
Hataishi, R1
Hirose, M1
Kobayashi, H1
Jing, L1
Wang, Y1
Zhao, XM1
Zhao, B1
Han, JJ1
Qin, SC1
Sun, XJ1
Hayashida, K1
Sano, M2
Ohsawa, I1
Shinmura, K1
Tamaki, K1
Kimura, K1
Endo, J1
Katayama, T1
Kawamura, A1
Kohsaka, S1
Makino, S1
Ohta, S1
Ogawa, S1
Fukuda, K1
Sakai, K1
Cho, S1
Shibata, I1
Yoshitomi, O1
Maekawa, T1
Sumikawa, K1
Yoshida, A1
Sasaki, H1
Sanada, S1
Yamazaki, S1
Asano, Y1
Shinozaki, Y1
Mori, H1
Shimouchi, A1
Asakura, M1
Minamino, T1
Takashima, S1
Sugimachi, M1
Mochizuki, N1
Tiefenbacher, CP1
Kapitza, J1
Dietz, V1
Lee, CH1
Niroomand, F1
Barba, I1
Jaimez-Auguets, E1
Rodriguez-Sinovas, A1
Garcia-Dorado, D1
Scholz, TD1
Hoyt, RF1
DeLeonardis, JR1
Ceckler, TL1
Balaban, RS1
Fukuta, M1
Wakida, Y1
Iwa, T1
Uesugi, M1
Kobayashi, T1
Fluck, DS1
Etherington, PJ1
Sheridan, DJ1
Winlove, CP1
Takamatsu, T1
Toleikis, A1
Dzeja, P1
Praskevicius, A1
Jasaitis, A1
Neef, H1
Richter, RA1
Bretschneider, G1
Pauer, D1
Linke, PG1
Bouchard, A1
Doyle, M1
Wolkowicz, PE1
Wilson, R1
Evanochko, WT1
Pohost, GM1
Wittenberg, SM1
Klocke, FJ1
Greene, DG1
Bunnell, IL1
Falsetti, HL1
Zizzi, JA1
Jennings, RB1
Krug, A1
Krug, C1
Dharamadhach, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Metabolomic Profile of Patients Undergoing Myocardial Perfusion SPECT[NCT02968771]500 participants (Anticipated)Observational2016-11-30Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

21 other studies available for hydrogen and Cardiovascular Stroke

ArticleYear
Nanodiamonds and hydrogen-substituted graphdiyne heteronanostructure for the sensitive impedimetric aptasensing of myocardial infarction and cardiac troponin I.
    Analytica chimica acta, 2021, Jan-02, Volume: 1141

    Topics: Aptamers, Nucleotide; Biosensing Techniques; Electrochemical Techniques; Graphite; Humans; Hydrogen;

2021
Hydrogen gas inhalation alleviates myocardial ischemia-reperfusion injury by the inhibition of oxidative stress and NLRP3-mediated pyroptosis in rats.
    Life sciences, 2021, May-01, Volume: 272

    Topics: Administration, Inhalation; Animals; Cell Survival; Hydrogen; Inflammasomes; Male; Myocardial Infarc

2021
Hydrogen Attenuates Myocardial Injury in Rats by Regulating Oxidative Stress and NLRP3 Inflammasome Mediated Pyroptosis.
    International journal of medical sciences, 2021, Volume: 18, Issue:14

    Topics: Administration, Inhalation; Animals; Antioxidants; Disease Models, Animal; Echocardiography; Humans;

2021
Translational Study of Hydrogen Gas Inhalation as Adjuncts to Reperfusion Therapy for Acute Myocardial Infarction.
    Circulation journal : official journal of the Japanese Circulation Society, 2017, Jun-23, Volume: 81, Issue:7

    Topics: Humans; Hydrogen; Myocardial Infarction; Myocardial Reperfusion; Translational Research, Biomedical

2017
Breathing nitric oxide plus hydrogen gas reduces ischemia-reperfusion injury and nitrotyrosine production in murine heart.
    American journal of physiology. Heart and circulatory physiology, 2013, Aug-15, Volume: 305, Issue:4

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Inhalation; Aldehydes; Animals; Antioxidants; Cardioton

2013
Cardioprotective Effect of Hydrogen-rich Saline on Isoproterenol-induced Myocardial Infarction in Rats.
    Heart, lung & circulation, 2015, Volume: 24, Issue:6

    Topics: Analysis of Variance; Animals; Biomarkers; Biopsy, Needle; Cardiotonic Agents; Cytokines; Disease Mo

2015
Inhalation of hydrogen gas reduces infarct size in the rat model of myocardial ischemia-reperfusion injury.
    Biochemical and biophysical research communications, 2008, Aug-15, Volume: 373, Issue:1

    Topics: Animals; Cardiotonic Agents; Disease Models, Animal; Hydrogen; Inhalation; Male; Myocardial Infarcti

2008
Inhalation of hydrogen gas protects against myocardial stunning and infarction in swine.
    Scandinavian cardiovascular journal : SCJ, 2012, Volume: 46, Issue:3

    Topics: Administration, Inhalation; Animals; Cardiotonic Agents; Disease Models, Animal; Female; Gases; Hydr

2012
H(2) mediates cardioprotection via involvements of K(ATP) channels and permeability transition pores of mitochondria in dogs.
    Cardiovascular drugs and therapy, 2012, Volume: 26, Issue:3

    Topics: Animals; Apoptosis; Cardiotonic Agents; Decanoic Acids; Dogs; Hydrogen; Hydroxy Acids; In Situ Nick-

2012
Reduction of myocardial infarct size by fluvastatin.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:1

    Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Vessels; Cyclic GMP; Echocardiography, Doppl

2003
1H NMR-based metabolomic identification of at-risk areas after myocardial infarction in swine.
    Magma (New York, N.Y.), 2007, Volume: 20, Issue:5-6

    Topics: Animals; Disease Models, Animal; Hydrogen; Lipid Metabolism; Magnetic Resonance Spectroscopy; Metabo

2007
Water-macromolecular proton magnetization transfer in infarcted myocardium: a method to enhance magnetic resonance image contrast.
    Magnetic resonance in medicine, 1995, Volume: 33, Issue:2

    Topics: Animals; Body Water; Body Weight; Chronic Disease; Heart Ventricles; Hydrogen; Image Enhancement; Ma

1995
Role of Na(+)-H+ exchange on reperfusion related myocardial injury and arrhythmias in an open-chest swine model.
    Pacing and clinical electrophysiology : PACE, 1996, Volume: 19, Issue:11 Pt 2

    Topics: Action Potentials; Amiloride; Animals; Arrhythmias, Cardiac; Calcium; Cardiac Pacing, Artificial; Co

1996
Solute exchange in the rabbit myocardium: ischaemia, reflow, and myocardial necrosis.
    Basic research in cardiology, 1998, Volume: 93, Issue:5

    Topics: Animals; Arterial Occlusive Diseases; Capillary Permeability; Coronary Circulation; Coronary Disease

1998
Confocal microscopy. Applications in research and practice of pathology.
    Analytical and quantitative cytology and histology, 1998, Volume: 20, Issue:6

    Topics: Calcium; Humans; Hydrogen; Ions; Magnesium; Microscopy, Confocal; Myocardial Infarction; Myocardium;

1998
Mitochondrial functions in ischemic myocardium. I. Proton electrochemical gradient, inner membrane permeability, calcium transport and oxidative phosphorylation in isolated mitochondria.
    Journal of molecular and cellular cardiology, 1979, Volume: 11, Issue:1

    Topics: Animals; Calcium; Coronary Disease; Humans; Hydrogen; Mitochondria, Heart; Myocardial Infarction; Ox

1979
[Dye-marking and hydrogen clearance in demonstrating acute ischemic myocardial areas].
    Zeitschrift fur experimentelle Chirurgie, 1975, Volume: 8, Issue:4

    Topics: Animals; Blood Flow Velocity; Dogs; Female; Hydrogen; Male; Methylene Blue; Myocardial Infarction; M

1975
Visualization of altered myocardial lipids by 1H NMR chemical-shift imaging following ischemic insult.
    Magnetic resonance in medicine, 1991, Volume: 17, Issue:2

    Topics: Animals; Coronary Circulation; Dogs; Fourier Analysis; Hydrogen; In Vitro Techniques; Lipids; Magnet

1991
Measurement of cardiac output in man with a nonrecirculating indicator.
    The Journal of clinical investigation, 1971, Volume: 50, Issue:7

    Topics: Arteriosclerosis; Cardiac Catheterization; Cardiac Output; Chromatography, Gas; Coronary Disease; Dy

1971
Early phase of myocardial ischemic injury and infarction.
    The American journal of cardiology, 1969, Volume: 24, Issue:6

    Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Dogs; Glycogen; Histocytochemistry; Humans; Hydrogen;

1969
[Infarct size and enzyme histochemical changes in the rat heart following long term treatment with dipyridamol (Persantin) and occlusion of the coronary arteries].
    Zeitschrift fur Kreislaufforschung, 1970, Volume: 59, Issue:6

    Topics: Aminosalicylic Acids; Animals; Coronary Vessels; Dipyridamole; Heart; Hydrogen; Hydrogen-Ion Concent

1970