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hydrogen and Carbohydrate Metabolism, Inborn Error

hydrogen has been researched along with Carbohydrate Metabolism, Inborn Error in 22 studies

Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.

Research Excerpts

ExcerptRelevanceReference
"Breath hydrogen tests were carried out on 157 children either because they had chronic diarrhea or because they were on disaccharide-free diets."7.67Value of breath hydrogen analysis in management of diarrheal illness in childhood: comparison with duodenal biopsy. ( Davidson, GP; Robb, TA, 1985)
"The purpose of this study was to determine if sacrosidase, a liquid produced from Saccharomyces cerevisiae containing 6000 IU of sucrase activity per mg protein, prevented symptoms of diarrhea, abdominal cramps, gas, and bloating in patients with congenital sucrase-isomaltase deficiency (CSID) consuming a normal sucrose and carbohydrate-containing diet."5.09Sacrosidase therapy for congenital sucrase-isomaltase deficiency. ( Hyams, J; Justinich, C; Kastoff, G; McAdams, L; Stanford, L; Treem, WR, 1999)
"Breath hydrogen tests were carried out on 157 children either because they had chronic diarrhea or because they were on disaccharide-free diets."3.67Value of breath hydrogen analysis in management of diarrheal illness in childhood: comparison with duodenal biopsy. ( Davidson, GP; Robb, TA, 1985)
"The peak rise in breath hydrogen and the volume of excess pulmonary excretion of hydrogen in response to a 10 g dose of the non-abosorbable disaccharide, lactulose, was significantly lower in children with active gastroenteritis and diarrhea than in nondiarrheal controls."3.66H2 breath tests during diarrhea. ( García, R; Schneider, R; Solomons, NW; Viteri, FE; von Kaenel, VA, 1979)
"Hydrogen production was higher in patients with sucrase-isomaltase deficiency (mean, 96 ppm; range, 20 ppm to 432ppm) than in those with secondary sucrose malabsorption (mean, 21 ppm; range, 12ppm to 51ppm)."1.27Detection of primary and secondary sucrose malabsorption in children by means of the breath hydrogen technique. ( Davidson, GP; Robb, TA, 1983)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199013 (59.09)18.7374
1990's3 (13.64)18.2507
2000's3 (13.64)29.6817
2010's3 (13.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Däbritz, J1
Mühlbauer, M1
Domagk, D1
Voos, N1
Henneböhl, G1
Siemer, ML1
Foell, D1
Andalib, I1
Shah, H1
Bal, BS1
Shope, TR1
Finelli, FC1
Koch, TR1
Lembcke, B1
Hammer, HF1
Hammer, J1
Ford, RP1
Barnes, GL1
Barnes, G1
McKellar, W1
Lawrance, S1
Beró, T1
Past, T1
Tapsonyi, Z1
Mózsik, G1
Jávor, T1
Davidson, GP3
Robb, TA2
Gardiner, AJ1
Tarlow, MJ1
Symonds, J1
Hutchison, JG1
Sutherland, IT1
Douwes, AC1
Fernandes, J1
Bodánszky, H1
Soutter, V1
Leleiko, N1
Bartlett, K1
Dobson, JV1
Eastham, E1
Corazza, G1
Strocchi, A1
Sorge, M1
Bentai, G1
Gasbarrini, G1
Treem, WR2
Ahsan, N1
Sullivan, B1
Rossi, T1
Holmes, R1
Fitzgerald, J1
Proujansky, R1
Hyams, J2
McAdams, L1
Stanford, L1
Kastoff, G1
Justinich, C1
Lee, WS1
Moore, DJ1
Butler, RN1
Jouët, P1
Sabaté, JM1
Coffin, B1
Bouhnik, Y1
Lémann, M1
Jian, R1
Rambaud, JC1
Flourié, B1
Solomons, NW1
García, R1
Schneider, R1
Viteri, FE1
von Kaenel, VA1
Degli Esposti, A1
Ambrosioni, G1
Giardina, A1
Zaniboni, MG1
Sciarretta, G1
Payne-Bose, D1
Tsegaye, A1
Morrison, RD1
Waller, GR1
Harms, HK1
Bertele-Harms, RM1
Bruer-Kleis, D1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multicenter, Double-Blind, Placebo-Controlled Trial to Evaluate the Frequency of Genetic Sucrase-Isomaltase Deficiency Genotypes, and the Efficacy and Safety of Sucraid® (Sacrosidase) Oral Solution in Subjects With Chronic Diarrhea and Sucrase Deficienc[NCT02784067]Phase 40 participants (Actual)Interventional2016-05-31Withdrawn (stopped due to Clinical Trial Material)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for hydrogen and Carbohydrate Metabolism, Inborn Error

ArticleYear
Diarrhea caused by carbohydrate malabsorption.
    Gastroenterology clinics of North America, 2012, Volume: 41, Issue:3

    Topics: Anti-Bacterial Agents; Bacteria; Breath Tests; Carbohydrate Metabolism, Inborn Errors; Diarrhea; Die

2012

Trials

3 trials available for hydrogen and Carbohydrate Metabolism, Inborn Error

ArticleYear
Evaluation of liquid yeast-derived sucrase enzyme replacement in patients with sucrase-isomaltase deficiency.
    Gastroenterology, 1993, Volume: 105, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Analysis of Variance; Carbohydrate Metabolism, Inborn Error

1993
Sacrosidase therapy for congenital sucrase-isomaltase deficiency.
    Journal of pediatric gastroenterology and nutrition, 1999, Volume: 28, Issue:2

    Topics: Animals; Breath Tests; Carbohydrate Metabolism, Inborn Errors; Child; Child, Preschool; Diarrhea; Do

1999
Sugar intolerance: origin and mechanisms of symptoms?
    Digestive diseases and sciences, 2002, Volume: 47, Issue:4

    Topics: Adult; Breath Tests; Carbohydrate Metabolism, Inborn Errors; Colon; Female; Gastrointestinal Agents;

2002

Other Studies

18 other studies available for hydrogen and Carbohydrate Metabolism, Inborn Error

ArticleYear
Significance of hydrogen breath tests in children with suspected carbohydrate malabsorption.
    BMC pediatrics, 2014, Feb-27, Volume: 14

    Topics: Adolescent; Breath Tests; Carbohydrate Metabolism, Inborn Errors; Child; Child, Preschool; Female; F

2014
Breath Hydrogen as a Biomarker for Glucose Malabsorption after Roux-en-Y Gastric Bypass Surgery.
    Disease markers, 2015, Volume: 2015

    Topics: Adult; Biomarkers; Breath Tests; Carbohydrate Metabolism, Inborn Errors; Female; Gastric Bypass; Hum

2015
[Irritable bowel disease with flatulence: is the breath test for carbohydrate malabsorption obligatory? Contra].
    Deutsche medizinische Wochenschrift (1946), 2009, Volume: 134, Issue:37

    Topics: Breath Tests; Carbohydrate Metabolism, Inborn Errors; Diagnosis, Differential; False Positive Reacti

2009
Breath hydrogen test and sucrase isomaltase deficiency.
    Archives of disease in childhood, 1983, Volume: 58, Issue:8

    Topics: Breath Tests; Carbohydrate Metabolism, Inborn Errors; Child; Child, Preschool; Chromatography, Gas;

1983
Detection of fructose malabsorption by breath hydrogen test in a child with diarrhea.
    The Journal of pediatrics, 1983, Volume: 103, Issue:4

    Topics: Breath Tests; Carbohydrate Metabolism, Inborn Errors; Child; Diarrhea; Female; Fructose Intolerance;

1983
[Clinical significance of H2 determination in breath. A new method for the detection of carbohydrate malabsorption (preliminary report)].
    Orvosi hetilap, 1983, Jan-09, Volume: 124, Issue:2

    Topics: Breath Tests; Carbohydrate Metabolism, Inborn Errors; Humans; Hydrogen; Intestinal Absorption; Malab

1983
Detection of primary and secondary sucrose malabsorption in children by means of the breath hydrogen technique.
    The Medical journal of Australia, 1983, Jul-09, Volume: 2, Issue:1

    Topics: Breath Tests; Carbohydrate Metabolism, Inborn Errors; Child; Humans; Hydrogen; Malabsorption Syndrom

1983
Failure of the hydrogen breath test to detect pulmonary sugar malabsorption.
    Archives of disease in childhood, 1981, Volume: 56, Issue:5

    Topics: Adolescent; Breath Tests; Carbohydrate Metabolism, Inborn Errors; Child; Child, Preschool; False Neg

1981
[Diagnosis of carbohydrate malabsorption].
    Tijdschrift voor kindergeneeskunde, 1981, Volume: 49, Issue:1

    Topics: Biopsy; Blood Glucose; Breath Tests; Carbohydrate Metabolism, Inborn Errors; Carbohydrates; Child; F

1981
[Determination of hydrogen in the exhaled air as a diagnostic method in carbohydrate metabolism disorders].
    Orvosi hetilap, 1981, Aug-16, Volume: 122, Issue:33

    Topics: Breath Tests; Carbohydrate Metabolism, Inborn Errors; Humans; Hydrogen

1981
A new method for the detection of hydrogen in breath and its application to acquired and inborn sugar malabsorption.
    Clinica chimica acta; international journal of clinical chemistry, 1980, Dec-08, Volume: 108, Issue:2

    Topics: Aged; Breath Tests; Carbohydrate Metabolism, Inborn Errors; Child; Child, Preschool; Female; Gastroi

1980
Prevalence and consistency of low breath H2 excretion following lactulose ingestion. Possible implications for the clinical use of the H2 breath test.
    Digestive diseases and sciences, 1993, Volume: 38, Issue:11

    Topics: Adult; Breath Tests; Carbohydrate Metabolism, Inborn Errors; Female; Humans; Hydrogen; Lactulose; Ma

1993
Analysis of the breath hydrogen test for carbohydrate malabsorption: validation of a pocket-sized breath test analyser.
    Journal of paediatrics and child health, 2000, Volume: 36, Issue:4

    Topics: Adolescent; Adult; Breath Tests; Carbohydrate Metabolism, Inborn Errors; Child; Child, Preschool; Fe

2000
H2 breath tests during diarrhea.
    Acta paediatrica Scandinavica, 1979, Volume: 68, Issue:2

    Topics: Breath Tests; Carbohydrate Metabolism, Inborn Errors; Child, Preschool; Diarrhea, Infantile; Gastroe

1979
[Evaluation of sugar intolerance by means of the hydrogen (H2) breath test in a preliminary pediatric case study. Use of an original apparatus for breath collection].
    Minerva pediatrica, 1979, May-31, Volume: 31, Issue:10

    Topics: Breath Tests; Carbohydrate Metabolism, Inborn Errors; Child; Child, Preschool; Female; Humans; Hydro

1979
An improved method for determining breath H2 as an indicator of carbohydrate malabsorption.
    Analytical biochemistry, 1978, Aug-01, Volume: 88, Issue:2

    Topics: Adult; Breath Tests; Carbohydrate Metabolism, Inborn Errors; Chromatography, Gas; Female; Humans; Hy

1978
Enzyme-substitution therapy with the yeast Saccharomyces cerevisiae in congenital sucrase-isomaltase deficiency.
    The New England journal of medicine, 1987, May-21, Volume: 316, Issue:21

    Topics: Adolescent; Adult; Breath Tests; Carbohydrate Metabolism, Inborn Errors; Child; Child, Preschool; Fe

1987
Value of breath hydrogen analysis in management of diarrheal illness in childhood: comparison with duodenal biopsy.
    Journal of pediatric gastroenterology and nutrition, 1985, Volume: 4, Issue:3

    Topics: Biopsy; Breath Tests; Carbohydrate Metabolism, Inborn Errors; Child, Preschool; Diarrhea; Duodenum;

1985