Page last updated: 2024-10-18

hydrogen and Allodynia

hydrogen has been researched along with Allodynia in 6 studies

Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.

Research Excerpts

ExcerptRelevanceReference
"To investigate the role of autophagy in hydrogen-rich saline attenuating post-herpetic neuralgia( PHN) in rats."7.85[Hydrogen-rich saline attenuates hyperalgesia and reduces cytokines in rats with post-herpetic neuralgia via activating autophagy]. ( Bian, Y; Chen, H; Dong, A; Ma, H; Wang, Y; Xie, K, 2017)
"To investigate the role of autophagy in hydrogen-rich saline attenuating post-herpetic neuralgia( PHN) in rats."3.85[Hydrogen-rich saline attenuates hyperalgesia and reduces cytokines in rats with post-herpetic neuralgia via activating autophagy]. ( Bian, Y; Chen, H; Dong, A; Ma, H; Wang, Y; Xie, K, 2017)
"In a rat model of neuropathic pain induced by L5 spinal nerve ligation (L5 SNL), intrathecal injection of hydrogen-rich normal saline relieved L5 SNL-induced mechanical allodynia and thermal hyperalgesia."3.80Intrathecal infusion of hydrogen-rich normal saline attenuates neuropathic pain via inhibition of activation of spinal astrocytes and microglia in rats. ( Ge, Y; Huang, S; Lu, Z; Sun, X; Sun, Y; Wu, F; Xiang, Z; Yang, L; Yu, WF, 2014)
"Hydrogen treatment could alleviate hyperpathia by autophagy-mediated NLRP3 inactivation."1.51Hydrogen-rich Saline Alleviated the Hyperpathia and Microglia Activation via Autophagy Mediated Inflammasome Inactivation in Neuropathic Pain Rats. ( Chen, H; Meng, X; Wang, Y; Xie, K; Yu, Y; Zhou, C, 2019)
"When hydrogen was administered only for the maintenance phase (from day 4 to 21 after ligation), hyperalgesia but not allodynia was alleviated."1.40Molecular hydrogen attenuates neuropathic pain in mice. ( Kawaguchi, M; Kazama, T; Otsubo, Y; Satoh, Y, 2014)
"Mechanical and thermal hyperalgesia were evaluated by measuring PWT and PWL for 48 post-infusion hours, respectively."1.40Hydrogen-rich saline controls remifentanil-induced hypernociception and NMDA receptor NR1 subunit membrane trafficking through GSK-3β in the DRG in rats. ( Li, N; Shu, R; Wang, C; Wang, G; Wang, H; Zhang, L, 2014)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, H2
Zhou, C1
Xie, K2
Meng, X1
Wang, Y2
Yu, Y2
Ma, H1
Dong, A1
Bian, Y1
Ge, Y1
Wu, F1
Sun, X1
Xiang, Z1
Yang, L1
Huang, S1
Lu, Z1
Sun, Y1
Yu, WF1
Kawaguchi, M1
Satoh, Y1
Otsubo, Y1
Kazama, T1
Zhang, L2
Shu, R2
Wang, C2
Wang, H2
Li, N1
Wang, G2
Yang, M1
Wang, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Perioperative Hydrogen Inhalation on Post-operative Pain and Inflammation Cytokines[NCT05476575]32 participants (Anticipated)Interventional2021-10-28Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

6 other studies available for hydrogen and Allodynia

ArticleYear
Hydrogen-rich Saline Alleviated the Hyperpathia and Microglia Activation via Autophagy Mediated Inflammasome Inactivation in Neuropathic Pain Rats.
    Neuroscience, 2019, 11-21, Volume: 421

    Topics: Animals; Autophagy; Behavior Rating Scale; Calcium-Binding Proteins; CARD Signaling Adaptor Proteins

2019
[Hydrogen-rich saline attenuates hyperalgesia and reduces cytokines in rats with post-herpetic neuralgia via activating autophagy].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2017, Volume: 33, Issue:2

    Topics: Animals; Autophagy; Hydrogen; Hyperalgesia; Interleukin-1beta; Interleukin-6; Male; Microtubule-Asso

2017
Intrathecal infusion of hydrogen-rich normal saline attenuates neuropathic pain via inhibition of activation of spinal astrocytes and microglia in rats.
    PloS one, 2014, Volume: 9, Issue:5

    Topics: Animals; Astrocytes; Cytokines; Gene Expression Regulation, Enzymologic; Hydrogen; Hydroxides; Hyper

2014
Molecular hydrogen attenuates neuropathic pain in mice.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Analgesics; Animals; Antioxidants; Deoxyguanosine; Drinking

2014
Hydrogen-rich saline controls remifentanil-induced hypernociception and NMDA receptor NR1 subunit membrane trafficking through GSK-3β in the DRG in rats.
    Brain research bulletin, 2014, Volume: 106

    Topics: Analgesics, Opioid; Animals; Cell Membrane; Ganglia, Spinal; Glycogen Synthase Kinase 3; Glycogen Sy

2014
Hydrogen-rich saline prevents remifentanil-induced hyperalgesia and inhibits MnSOD nitration via regulation of NR2B-containing NMDA receptor in rats.
    Neuroscience, 2014, Nov-07, Volume: 280

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Excitatory Amino Acid Antagonists; Hot Temper

2014