hydrogen has been researched along with Acute Lung Injury in 37 studies
Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.
Acute Lung Injury: A condition of lung damage that is characterized by bilateral pulmonary infiltrates (PULMONARY EDEMA) rich in NEUTROPHILS, and in the absence of clinical HEART FAILURE. This can represent a spectrum of pulmonary lesions, endothelial and epithelial, due to numerous factors (physical, chemical, or biological).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although hydrogen has been proved to be a novel therapeutic medical gas in several lung injury animal models, to our knowledge, it has not been tested yet in acute lung injury (ALI) induced by cecal ligation and puncture (CLP)." | 8.91 | Hydrogen-rich saline ameliorates lung injury associated with cecal ligation and puncture-induced sepsis in rats. ( Dai, Q; Fan, Y; Huang, X; Zhai, Y; Zhou, X, 2015) |
| "The aim of this study was to investigate the efficacy and underlying mechanism of high concentration of hydrogen on lipopolysaccharide (LPS)-induced acute lung injury (ALI)." | 8.12 | High concentration of hydrogen ameliorates lipopolysaccharide-induced acute lung injury in a sirt1-dependent manner. ( Du, J; Li, J; Li, R; Yan, X, 2022) |
| "These results suggest that PINK1-mediated mitophagy plays a key role in the protective effects of hydrogen against cell injury in LPS-induced inflammation and CLP-induced acute lung injury." | 8.02 | Hydrogen alleviates cell damage and acute lung injury in sepsis via PINK1/Parkin-mediated mitophagy. ( Chen, H; Dong, B; Lin, H; Wang, Y; Xie, K; Yu, Y, 2021) |
| " The hypothesis of this study is that hydrogen-rich solution could attenuateacute lung injury and improve mortality via chemerin and NLRP3 after LI/R in rats." | 7.91 | Hydrogen-Rich Saline Attenuates Acute Lung Injury Induced by Limb Ischemia/Reperfusion via Down-Regulating Chemerin and NLRP3 in Rats. ( Chen, Y; Du, J; Fan, X; Liu, KX; Wang, MH; Wang, XB; Yang, B; Zhou, J; Zou, R, 2019) |
| "Purpose/Aim: Exposure to hyperoxia leads to lung injury both in vivo and in vitro, molecular hydrogen has been reported to protect against hyperoxia-induced lung injury; however, the underlying molecular mechanisms remain largely unknown." | 7.88 | Quantitative proteomics reveals the mechanisms of hydrogen-conferred protection against hyperoxia-induced injury in type II alveolar epithelial cells. ( Lu, X; Wang, C; Wu, D; Xiao, C; Xu, F; Zhang, C, 2018) |
| "Inhaled hydrogen gas (H2) provides protection in rat models of human acute lung injury (ALI)." | 7.85 | Protection by Inhaled Hydrogen Therapy in a Rat Model of Acute Lung Injury can be Tracked in vivo Using Molecular Imaging. ( Audi, SH; Camara, AKS; Clough, AV; Jacobs, ER; Medhora, MM; Rizzo, B; Zhang, X; Zhao, M, 2017) |
| "The purpose of the study is to investigate the role and mechanisms of hydrogen-saturated saline (HSS) in the acute lung injury (ALI) induced by oleic acid (OA) in rats." | 7.85 | Protective effect of hydrogen-saturated saline on acute lung injury induced by oleic acid in rats. ( Qin, Z; Xu, H; Yao, M; Ying, Y, 2017) |
| "To investigate the role of Rho/ROCK signaling pathway in the protective effects of hydrogen gas (H2) on acute lung injury (ALI) in a mouse model of sepsis." | 7.83 | [Role of Rho/ROCK signaling pathway in the protective effects of hydrogen against acute lung injury in septic mice]. ( Liang, Y; Liu, L; Sun, Z; Yu, Y; Zhang, H, 2016) |
| "To investigate the effect of hydrogen inhalation on acute lung injury after hemorrhagic shock in rats." | 7.79 | [The effect of hydrogen on hemorrhagic shock induced acute lung injury in rats]. ( Jia, YR; Liu, JF; Shi, HM; Wang, Y; Zhou, HC, 2013) |
| "To investigate the effect of hydrogen inhalation on lipopolysaccharide (LPS)-induced acute lung injury (ALI) and the underlying molecular mechanisms." | 7.78 | [Effect of hydrogen inhalation on p38 MAPK activation in rats with lipopolysaccharide- induced acute lung injury]. ( He, D; Liang, C; Liu, L; Liu, X, 2012) |
| "Exposure to paraquat leads to acute lung injury and oxidative stress is widely accepted as a contributor to paraquat-induced acute lung injury." | 7.77 | Consumption of hydrogen water reduces paraquat-induced acute lung injury in rats. ( Denoble, P; Liu, K; Liu, S; Liu, W; Sun, Q; Sun, X; Tao, H; Xu, W, 2011) |
| "Hydrogen could inhibit the upregulation of autophagy in the present rodent model." | 5.62 | Hydrogen alleviates acute lung injury induced by limb ischaemia/reperfusion in mice. ( Liu, B; Liu, L; Qi, X; Qiu, T; Shen, X; Song, G; Yang, C, 2021) |
| "Rats were subjected to hemorrhagic shock by withdrawing blood to lower blood pressure followed by resuscitation with shed blood and saline to restore blood pressure." | 5.42 | Hydrogen inhalation protects against acute lung injury induced by hemorrhagic shock and resuscitation. ( Aoyama-Ishikawa, M; Billiar, TR; Kohama, K; Kotani, J; Nakao, A; Nishimura, T; Takahashi, T; Yamashita, H, 2015) |
| "Hydrogen gas treatment inhibited LPS-induced pulmonary early and late NF-κB activation." | 5.38 | Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and apoptosis. ( Chen, H; Gong, G; Han, H; Hou, L; Huang, Y; Li, J; Wang, G; Xie, K; Yu, Y; Zheng, L, 2012) |
| "Although hydrogen has been proved to be a novel therapeutic medical gas in several lung injury animal models, to our knowledge, it has not been tested yet in acute lung injury (ALI) induced by cecal ligation and puncture (CLP)." | 4.91 | Hydrogen-rich saline ameliorates lung injury associated with cecal ligation and puncture-induced sepsis in rats. ( Dai, Q; Fan, Y; Huang, X; Zhai, Y; Zhou, X, 2015) |
| "The aim of this study was to investigate the efficacy and underlying mechanism of high concentration of hydrogen on lipopolysaccharide (LPS)-induced acute lung injury (ALI)." | 4.12 | High concentration of hydrogen ameliorates lipopolysaccharide-induced acute lung injury in a sirt1-dependent manner. ( Du, J; Li, J; Li, R; Yan, X, 2022) |
| " In the past 10 years, gas medical studies have found that both hydrogen molecules and oxygen molecules have protective effects on acute lung injury by improving inflammatory reactions and hypoxia, respectively." | 4.12 | Hydrogen-rich and hyperoxygenate saline inhibits lipopolysaccharide-induced lung injury through mediating NF-κB/NLRP3 signaling pathway in C57BL/6 mice. ( Cao, K; Fan, Y; Feng, Z; Liu, J; Wang, J; Xu, H, 2022) |
| "These results suggest that PINK1-mediated mitophagy plays a key role in the protective effects of hydrogen against cell injury in LPS-induced inflammation and CLP-induced acute lung injury." | 4.02 | Hydrogen alleviates cell damage and acute lung injury in sepsis via PINK1/Parkin-mediated mitophagy. ( Chen, H; Dong, B; Lin, H; Wang, Y; Xie, K; Yu, Y, 2021) |
| " The hypothesis of this study is that hydrogen-rich solution could attenuateacute lung injury and improve mortality via chemerin and NLRP3 after LI/R in rats." | 3.91 | Hydrogen-Rich Saline Attenuates Acute Lung Injury Induced by Limb Ischemia/Reperfusion via Down-Regulating Chemerin and NLRP3 in Rats. ( Chen, Y; Du, J; Fan, X; Liu, KX; Wang, MH; Wang, XB; Yang, B; Zhou, J; Zou, R, 2019) |
| "Purpose/Aim: Exposure to hyperoxia leads to lung injury both in vivo and in vitro, molecular hydrogen has been reported to protect against hyperoxia-induced lung injury; however, the underlying molecular mechanisms remain largely unknown." | 3.88 | Quantitative proteomics reveals the mechanisms of hydrogen-conferred protection against hyperoxia-induced injury in type II alveolar epithelial cells. ( Lu, X; Wang, C; Wu, D; Xiao, C; Xu, F; Zhang, C, 2018) |
| "The purpose of the study is to investigate the role and mechanisms of hydrogen-saturated saline (HSS) in the acute lung injury (ALI) induced by oleic acid (OA) in rats." | 3.85 | Protective effect of hydrogen-saturated saline on acute lung injury induced by oleic acid in rats. ( Qin, Z; Xu, H; Yao, M; Ying, Y, 2017) |
| "Inhaled hydrogen gas (H2) provides protection in rat models of human acute lung injury (ALI)." | 3.85 | Protection by Inhaled Hydrogen Therapy in a Rat Model of Acute Lung Injury can be Tracked in vivo Using Molecular Imaging. ( Audi, SH; Camara, AKS; Clough, AV; Jacobs, ER; Medhora, MM; Rizzo, B; Zhang, X; Zhao, M, 2017) |
| "To investigate the role of Rho/ROCK signaling pathway in the protective effects of hydrogen gas (H2) on acute lung injury (ALI) in a mouse model of sepsis." | 3.83 | [Role of Rho/ROCK signaling pathway in the protective effects of hydrogen against acute lung injury in septic mice]. ( Liang, Y; Liu, L; Sun, Z; Yu, Y; Zhang, H, 2016) |
| "To investigate the effect of hydrogen inhalation on acute lung injury after hemorrhagic shock in rats." | 3.79 | [The effect of hydrogen on hemorrhagic shock induced acute lung injury in rats]. ( Jia, YR; Liu, JF; Shi, HM; Wang, Y; Zhou, HC, 2013) |
| "To investigate the effect of hydrogen inhalation on lipopolysaccharide (LPS)-induced acute lung injury (ALI) and the underlying molecular mechanisms." | 3.78 | [Effect of hydrogen inhalation on p38 MAPK activation in rats with lipopolysaccharide- induced acute lung injury]. ( He, D; Liang, C; Liu, L; Liu, X, 2012) |
| "Exposure to paraquat leads to acute lung injury and oxidative stress is widely accepted as a contributor to paraquat-induced acute lung injury." | 3.77 | Consumption of hydrogen water reduces paraquat-induced acute lung injury in rats. ( Denoble, P; Liu, K; Liu, S; Liu, W; Sun, Q; Sun, X; Tao, H; Xu, W, 2011) |
| "Because inhaled hydrogen provides potent anti-inflammatory and antiapoptotic effects against acute lung injury, we hypothesized that treatment of organ donors with inhaled hydrogen during mechanical ventilation would decrease graft injury after lung transplantation." | 3.77 | The effect of donor treatment with hydrogen on lung allograft function in rats. ( Billiar, TR; Huang, CS; Kawamura, T; Masutani, K; Nakao, A; Okumura, M; Peng, X; Shigemura, N; Toyoda, Y, 2011) |
| "For example, coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global pandemic." | 1.72 | Molecular hydrogen is a promising therapeutic agent for pulmonary disease. ( Fu, Z; Zhang, J, 2022) |
| "Hydrogen could inhibit the upregulation of autophagy in the present rodent model." | 1.62 | Hydrogen alleviates acute lung injury induced by limb ischaemia/reperfusion in mice. ( Liu, B; Liu, L; Qi, X; Qiu, T; Shen, X; Song, G; Yang, C, 2021) |
| "Hydrogen inhalation has recently been shown to be an effective treatment for inflammatory lung injury, but the underlying mechanism is unknown." | 1.62 | Hydrogen Attenuates Endotoxin-Induced Lung Injury by Activating Thioredoxin 1 and Decreasing Tissue Factor Expression. ( Cheng, H; Duan, M; Hu, F; Hu, L; Jiang, L; Li, J; Li, Q; Liu, WT; Long, Y; Shi, Y; Wan, B; Xu, M; Yu, P; Yu, W, 2021) |
| "Rats were subjected to hemorrhagic shock by withdrawing blood to lower blood pressure followed by resuscitation with shed blood and saline to restore blood pressure." | 1.42 | Hydrogen inhalation protects against acute lung injury induced by hemorrhagic shock and resuscitation. ( Aoyama-Ishikawa, M; Billiar, TR; Kohama, K; Kotani, J; Nakao, A; Nishimura, T; Takahashi, T; Yamashita, H, 2015) |
| "Hydrogen-saline may increase expression of HO-1 and alleviate oxidative stress damage in lung." | 1.42 | [Effect of hydrogen-saline on lung injury and heme oxygenase-1 expression in the lung tissue of acute paraquat-intoxicated mice]. ( Ge, Y; Jiang, Y; Liu, G; Song, D, 2015) |
| "The process of brain death induces acute lung injury in donors and aggravates ischemia-reperfusion injury (IRI) in grafts." | 1.39 | Hydrogen inhalation decreases lung graft injury in brain-dead donor rats. ( Cui, X; Ding, W; Fu, Z; Li, W; Liu, J; Pan, P; Wei, Y; Yang, W; Zhou, H, 2013) |
| "Hydrogen gas treatment inhibited LPS-induced pulmonary early and late NF-κB activation." | 1.38 | Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and apoptosis. ( Chen, H; Gong, G; Han, H; Hou, L; Huang, Y; Li, J; Wang, G; Xie, K; Yu, Y; Zheng, L, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 27 (72.97) | 24.3611 |
| 2020's | 10 (27.03) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, R | 1 |
| Zhao, N | 1 |
| Wang, Y | 12 |
| Su, Y | 1 |
| Zhang, J | 10 |
| Yu, Y | 7 |
| Wang, G | 2 |
| Wang, Z | 3 |
| Xie, K | 5 |
| Du, J | 2 |
| Li, J | 11 |
| Li, R | 1 |
| Yan, X | 2 |
| Fu, Z | 4 |
| Zhang, Y | 9 |
| Fan, Y | 4 |
| Wang, J | 7 |
| Feng, Z | 1 |
| Cao, K | 1 |
| Liu, J | 7 |
| Xu, H | 4 |
| Ageta, K | 1 |
| Hirayama, T | 1 |
| Aokage, T | 1 |
| Seya, M | 1 |
| Meng, Y | 1 |
| Nojima, T | 1 |
| Yamamoto, H | 1 |
| Obara, T | 1 |
| Nakao, A | 3 |
| Yumoto, T | 1 |
| Tsukahara, K | 1 |
| Naito, H | 1 |
| Zhang, Z | 3 |
| Wu, X | 3 |
| Halim, AA | 1 |
| Alsayed, B | 1 |
| Embarak, S | 1 |
| Yaseen, T | 1 |
| Dabbous, S | 1 |
| Fontaine, O | 1 |
| Dueluzeau, R | 1 |
| Raibaud, P | 1 |
| Chabanet, C | 1 |
| Popoff, MR | 1 |
| Badoual, J | 1 |
| Gabilan, JC | 1 |
| Andremont, A | 1 |
| Gómez, L | 1 |
| Andrés, S | 1 |
| Sánchez, J | 1 |
| Alonso, JM | 1 |
| Rey, J | 1 |
| López, F | 1 |
| Jiménez, A | 1 |
| Yan, Z | 1 |
| Zhou, L | 1 |
| Zhao, Y | 3 |
| Huang, L | 2 |
| Hu, K | 1 |
| Liu, H | 5 |
| Wang, H | 3 |
| Guo, Z | 1 |
| Song, Y | 1 |
| Huang, H | 4 |
| Yang, R | 1 |
| Owen, TW | 1 |
| Al-Kaysi, RO | 1 |
| Bardeen, CJ | 1 |
| Cheng, Q | 1 |
| Wu, S | 1 |
| Cheng, T | 1 |
| Zhou, X | 2 |
| Wang, B | 4 |
| Zhang, Q | 4 |
| Yao, Y | 3 |
| Ochiai, T | 1 |
| Ishiguro, H | 2 |
| Nakano, R | 2 |
| Kubota, Y | 2 |
| Hara, M | 1 |
| Sunada, K | 1 |
| Hashimoto, K | 1 |
| Kajioka, J | 1 |
| Fujishima, A | 1 |
| Jiao, J | 3 |
| Gai, QY | 3 |
| Wang, W | 2 |
| Zang, YP | 2 |
| Niu, LL | 2 |
| Fu, YJ | 3 |
| Wang, X | 5 |
| Yao, LP | 1 |
| Qin, QP | 1 |
| Wang, ZY | 1 |
| Aleksic Sabo, V | 1 |
| Knezevic, P | 1 |
| Borges-Argáez, R | 1 |
| Chan-Balan, R | 1 |
| Cetina-Montejo, L | 1 |
| Ayora-Talavera, G | 1 |
| Sansores-Peraza, P | 1 |
| Gómez-Carballo, J | 1 |
| Cáceres-Farfán, M | 1 |
| Jang, J | 1 |
| Akin, D | 1 |
| Bashir, R | 1 |
| Yu, Z | 1 |
| Zhu, J | 3 |
| Jiang, H | 1 |
| He, C | 2 |
| Xiao, Z | 1 |
| Xu, J | 2 |
| Sun, Q | 3 |
| Han, D | 1 |
| Lei, H | 1 |
| Zhao, K | 2 |
| Zhu, L | 1 |
| Li, X | 4 |
| Fu, H | 2 |
| Wilson, BK | 1 |
| Step, DL | 1 |
| Maxwell, CL | 1 |
| Gifford, CA | 1 |
| Richards, CJ | 1 |
| Krehbiel, CR | 1 |
| Warner, JM | 1 |
| Doerr, AJ | 1 |
| Erickson, GE | 1 |
| Guretzky, JA | 1 |
| Rasby, RJ | 1 |
| Watson, AK | 1 |
| Klopfenstein, TJ | 1 |
| Sun, Y | 4 |
| Liu, Z | 4 |
| Pham, TD | 1 |
| Lee, BK | 1 |
| Yang, FC | 1 |
| Wu, KH | 1 |
| Lin, WP | 1 |
| Hu, MK | 1 |
| Lin, L | 3 |
| Shao, J | 1 |
| Sun, M | 1 |
| Xu, G | 1 |
| Zhang, X | 7 |
| Xu, N | 1 |
| Wang, R | 1 |
| Liu, S | 2 |
| He, H | 1 |
| Dong, X | 2 |
| Yang, M | 2 |
| Yang, Q | 1 |
| Duan, S | 1 |
| Han, J | 2 |
| Zhang, C | 4 |
| Chen, L | 2 |
| Yang, X | 1 |
| Li, W | 5 |
| Wang, T | 2 |
| Campbell, DA | 1 |
| Gao, K | 1 |
| Zager, RA | 1 |
| Johnson, ACM | 1 |
| Guillem, A | 1 |
| Keyser, J | 1 |
| Singh, B | 1 |
| Steubl, D | 1 |
| Schneider, MP | 1 |
| Meiselbach, H | 1 |
| Nadal, J | 1 |
| Schmid, MC | 1 |
| Saritas, T | 1 |
| Krane, V | 1 |
| Sommerer, C | 1 |
| Baid-Agrawal, S | 1 |
| Voelkl, J | 1 |
| Kotsis, F | 1 |
| Köttgen, A | 1 |
| Eckardt, KU | 1 |
| Scherberich, JE | 1 |
| Li, H | 5 |
| Yao, L | 2 |
| Sun, L | 3 |
| Zhu, Z | 1 |
| Naren, N | 1 |
| Zhang, XX | 2 |
| Gentile, GL | 1 |
| Rupert, AS | 1 |
| Carrasco, LI | 1 |
| Garcia, EM | 1 |
| Kumar, NG | 1 |
| Walsh, SW | 1 |
| Jefferson, KK | 1 |
| Guest, RL | 1 |
| Samé Guerra, D | 1 |
| Wissler, M | 1 |
| Grimm, J | 1 |
| Silhavy, TJ | 1 |
| Lee, JH | 2 |
| Yoo, JS | 1 |
| Kim, Y | 1 |
| Kim, JS | 2 |
| Lee, EJ | 1 |
| Roe, JH | 1 |
| Delorme, M | 1 |
| Bouchard, PA | 1 |
| Simon, M | 1 |
| Simard, S | 1 |
| Lellouche, F | 1 |
| D'Urzo, KA | 1 |
| Mok, F | 1 |
| D'Urzo, AD | 1 |
| Koneru, B | 1 |
| Lopez, G | 1 |
| Farooqi, A | 1 |
| Conkrite, KL | 1 |
| Nguyen, TH | 1 |
| Macha, SJ | 1 |
| Modi, A | 1 |
| Rokita, JL | 1 |
| Urias, E | 1 |
| Hindle, A | 1 |
| Davidson, H | 1 |
| Mccoy, K | 1 |
| Nance, J | 1 |
| Yazdani, V | 1 |
| Irwin, MS | 1 |
| Yang, S | 1 |
| Wheeler, DA | 1 |
| Maris, JM | 1 |
| Diskin, SJ | 1 |
| Reynolds, CP | 1 |
| Abhilash, L | 1 |
| Kalliyil, A | 1 |
| Sheeba, V | 1 |
| Hartley, AM | 2 |
| Meunier, B | 2 |
| Pinotsis, N | 1 |
| Maréchal, A | 2 |
| Xu, JY | 1 |
| Genko, N | 1 |
| Haraux, F | 1 |
| Rich, PR | 1 |
| Kamalanathan, M | 1 |
| Doyle, SM | 1 |
| Xu, C | 1 |
| Achberger, AM | 1 |
| Wade, TL | 1 |
| Schwehr, K | 1 |
| Santschi, PH | 1 |
| Sylvan, JB | 1 |
| Quigg, A | 1 |
| Leong, W | 1 |
| Xu, W | 4 |
| Gao, S | 1 |
| Zhai, X | 1 |
| Wang, C | 3 |
| Gilson, E | 1 |
| Ye, J | 1 |
| Lu, Y | 1 |
| Yan, R | 1 |
| Hu, Z | 1 |
| You, Q | 1 |
| Cai, Q | 1 |
| Yang, D | 1 |
| Gu, S | 1 |
| Dai, H | 1 |
| Zhao, X | 2 |
| Gui, C | 1 |
| Gui, J | 1 |
| Wu, PK | 1 |
| Hong, SK | 1 |
| Starenki, D | 1 |
| Oshima, K | 1 |
| Shao, H | 1 |
| Gestwicki, JE | 1 |
| Tsai, S | 1 |
| Park, JI | 1 |
| Zhao, R | 1 |
| Gu, Z | 1 |
| Dong, C | 2 |
| Guo, G | 1 |
| Li, L | 4 |
| Barrett, HE | 1 |
| Meester, EJ | 1 |
| van Gaalen, K | 1 |
| van der Heiden, K | 1 |
| Krenning, BJ | 1 |
| Beekman, FJ | 1 |
| de Blois, E | 1 |
| de Swart, J | 1 |
| Verhagen, HJ | 1 |
| Maina, T | 1 |
| Nock, BA | 1 |
| Norenberg, JP | 1 |
| de Jong, M | 1 |
| Gijsen, FJH | 1 |
| Bernsen, MR | 1 |
| Martínez-Milla, J | 1 |
| Galán-Arriola, C | 1 |
| Carnero, M | 1 |
| Cobiella, J | 1 |
| Pérez-Camargo, D | 1 |
| Bautista-Hernández, V | 1 |
| Rigol, M | 1 |
| Solanes, N | 1 |
| Villena-Gutierrez, R | 1 |
| Lobo, M | 1 |
| Mateo, J | 1 |
| Vilchez-Tschischke, JP | 1 |
| Salinas, B | 1 |
| Cussó, L | 1 |
| López, GJ | 1 |
| Fuster, V | 1 |
| Desco, M | 1 |
| Sanchez-González, J | 1 |
| Ibanez, B | 1 |
| van den Berg, P | 1 |
| Schweitzer, DH | 1 |
| van Haard, PMM | 1 |
| Geusens, PP | 1 |
| van den Bergh, JP | 1 |
| Zhu, X | 1 |
| Huang, X | 3 |
| Yang, G | 2 |
| Lin, Z | 2 |
| Salem, HF | 1 |
| Nafady, MM | 1 |
| Kharshoum, RM | 1 |
| Abd El-Ghafar, OA | 1 |
| Farouk, HO | 1 |
| Domiciano, D | 1 |
| Nery, FC | 1 |
| de Carvalho, PA | 1 |
| Prudente, DO | 1 |
| de Souza, LB | 1 |
| Chalfun-Júnior, A | 1 |
| Paiva, R | 1 |
| Marchiori, PER | 1 |
| Lu, M | 2 |
| An, Z | 1 |
| Jiang, J | 2 |
| Du, S | 1 |
| Zhou, H | 2 |
| Cui, J | 1 |
| Wu, W | 1 |
| Liu, Y | 8 |
| Song, J | 1 |
| Lian, Q | 1 |
| Uddin Ahmad, Z | 1 |
| Gang, DD | 1 |
| Konggidinata, MI | 1 |
| Gallo, AA | 1 |
| Zappi, ME | 1 |
| Yang, TWW | 1 |
| Johari, Y | 1 |
| Burton, PR | 1 |
| Earnest, A | 1 |
| Shaw, K | 1 |
| Hare, JL | 1 |
| Brown, WA | 1 |
| Kim, GA | 1 |
| Han, S | 1 |
| Choi, GH | 1 |
| Choi, J | 1 |
| Lim, YS | 1 |
| Gallo, A | 1 |
| Cancelli, C | 1 |
| Ceron, E | 1 |
| Covino, M | 1 |
| Capoluongo, E | 1 |
| Pocino, K | 1 |
| Ianiro, G | 1 |
| Cammarota, G | 1 |
| Gasbarrini, A | 1 |
| Montalto, M | 1 |
| Somasundar, Y | 1 |
| Lu, IC | 1 |
| Mills, MR | 1 |
| Qian, LY | 1 |
| Olivares, X | 1 |
| Ryabov, AD | 1 |
| Collins, TJ | 1 |
| Zhao, L | 1 |
| Doddipatla, S | 1 |
| Thomas, AM | 1 |
| Nikolayev, AA | 1 |
| Galimova, GR | 1 |
| Azyazov, VN | 1 |
| Mebel, AM | 1 |
| Kaiser, RI | 1 |
| Guo, S | 1 |
| Yang, P | 1 |
| Yu, X | 2 |
| Wu, Y | 2 |
| Zhang, H | 3 |
| Yu, B | 2 |
| Han, B | 1 |
| George, MW | 1 |
| Moor, MB | 1 |
| Bonny, O | 1 |
| Langenberg, E | 1 |
| Paik, H | 1 |
| Smith, EH | 1 |
| Nair, HP | 1 |
| Hanke, I | 1 |
| Ganschow, S | 1 |
| Catalan, G | 1 |
| Domingo, N | 1 |
| Schlom, DG | 1 |
| Assefa, MK | 1 |
| Wu, G | 2 |
| Hayton, TW | 1 |
| Becker, B | 1 |
| Enikeev, D | 1 |
| Netsch, C | 1 |
| Gross, AJ | 1 |
| Laukhtina, E | 1 |
| Glybochko, P | 1 |
| Rapoport, L | 1 |
| Herrmann, TRW | 1 |
| Taratkin, M | 1 |
| Dai, W | 1 |
| Shi, J | 3 |
| Carreno, J | 1 |
| Kloner, RA | 1 |
| Pickersgill, NA | 1 |
| Vetter, JM | 1 |
| Kim, EH | 1 |
| Cope, SJ | 1 |
| Du, K | 1 |
| Venkatesh, R | 1 |
| Giardina, JD | 1 |
| Saad, NES | 1 |
| Bhayani, SB | 1 |
| Figenshau, RS | 1 |
| Eriksson, J | 1 |
| Landfeldt, E | 1 |
| Ireland, S | 1 |
| Jackson, C | 1 |
| Wyatt, E | 1 |
| Gaudig, M | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Adjuvant Therapy for Severe COPD Patients in the Stable Phase by an Oxyhydrogen Generator With Nebulizer: A Multi-centric, Randomized, Parallel-control and Double-blinded Clinic Study[NCT02850185] | 170 participants (Anticipated) | Interventional | 2016-07-15 | Recruiting | |||
| Evaluation of the Daily Intake of 0.5 L of Water Saturated With Molecular Hydrogen for 21 Days in COVID-19 Patients Treated in Ambulatory Care. Double-blind, Randomized, Comparative Study[NCT04716985] | 700 participants (Actual) | Interventional | 2021-01-22 | Active, not recruiting | |||
| The Effect of Perioperative Hydrogen Inhalation on Post-operative Pain and Inflammation Cytokines[NCT05476575] | 32 participants (Anticipated) | Interventional | 2021-10-28 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for hydrogen and Acute Lung Injury
| Article | Year |
|---|---|
Molecular hydrogen is a potential protective agent in the management of acute lung injury.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; COVID-19 Drug Treatment; Humans | 2022 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor P | 2016 |
Hydrogen-rich saline ameliorates lung injury associated with cecal ligation and puncture-induced sepsis in rats.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Cecum; Disease Models, Animal; D | 2015 |
1 trial available for hydrogen and Acute Lung Injury
34 other studies available for hydrogen and Acute Lung Injury
| Article | Year |
|---|---|
High concentration of hydrogen gas alleviates Lipopolysaccharide-induced lung injury via activating Nrf2 signaling pathway in mice.
Topics: Acute Lung Injury; Animals; Gene Expression Regulation; Hydrogen; Lipopolysaccharides; Lung; Mice; M | 2021 |
High concentration of hydrogen ameliorates lipopolysaccharide-induced acute lung injury in a sirt1-dependent manner.
Topics: Acute Lung Injury; Administration, Inhalation; Animals; Disease Models, Animal; Endothelial Cells; H | 2022 |
Molecular hydrogen is a promising therapeutic agent for pulmonary disease.
Topics: Acute Lung Injury; Aging; Animals; Anti-Inflammatory Agents; Antioxidants; Asthma; Autophagy; COVID- | 2022 |
Hydrogen-rich and hyperoxygenate saline inhibits lipopolysaccharide-induced lung injury through mediating NF-κB/NLRP3 signaling pathway in C57BL/6 mice.
Topics: Acute Lung Injury; Animals; Hydrogen; Hypoxia; Inflammation; Lipopolysaccharides; Lung; Mice; Mice, | 2022 |
Hydrogen inhalation attenuates lung contusion after blunt chest trauma in mice.
Topics: Acute Lung Injury; Animals; Contusions; Hydrogen; Lung; Lung Injury; Male; Mice; Mice, Inbred C57BL; | 2023 |
Hydrogen-Rich Saline Inhibits Lipopolysaccharide-Induced Acute Lung Injury and Endothelial Dysfunction by Regulating Autophagy through mTOR/TFEB Signaling Pathway.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Apoptosis; Autophagy; Basic Helix-Loop-Helix L | 2020 |
Hydrogen Attenuates Endotoxin-Induced Lung Injury by Activating Thioredoxin 1 and Decreasing Tissue Factor Expression.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Coculture Techniques; Disease Models, Animal; | 2021 |
Hydrogen alleviates acute lung injury induced by limb ischaemia/reperfusion in mice.
Topics: Acute Lung Injury; Animals; Extremities; Heme Oxygenase-1; Hydrogen; Male; Malondialdehyde; Mice; Mi | 2021 |
Hydrogen alleviates cell damage and acute lung injury in sepsis via PINK1/Parkin-mediated mitophagy.
Topics: Acute Lung Injury; Animals; Autophagy; Cell Line; Hydrogen; Inflammation; Lipopolysaccharides; Lung; | 2021 |
Hydrogen alleviates hyperoxic acute lung injury related endoplasmic reticulum stress in rats through upregulation of SIRT1.
Topics: Acute Lung Injury; Animals; Apoptosis; Carbazoles; Endoplasmic Reticulum Stress; Enzyme Activation; | 2017 |
Protection by Inhaled Hydrogen Therapy in a Rat Model of Acute Lung Injury can be Tracked in vivo Using Molecular Imaging.
Topics: Acute Lung Injury; Administration, Inhalation; Animals; Bacteriocins; Disease Models, Animal; Hydrog | 2017 |
Protective effect of hydrogen-saturated saline on acute lung injury induced by oleic acid in rats.
Topics: Acute Lung Injury; Animals; Bicarbonates; Carbon Dioxide; Hydrogen; Inflammation Mediators; Infusion | 2017 |
[Effects of hydrogen on the lung damage of mice at early stage of severe burn].
Topics: Acute Lung Injury; Animals; Body Surface Area; Burns; Enzyme-Linked Immunosorbent Assay; HMGB1 Prote | 2017 |
Hydrogen protects against hyperoxia-induced apoptosis in type II alveolar epithelial cells via activation of PI3K/Akt/Foxo3a signaling pathway.
Topics: Acute Lung Injury; Alveolar Epithelial Cells; Animals; Apoptosis; bcl-2-Associated X Protein; Bcl-2- | 2018 |
Hydrogen-Rich Saline Attenuates Acute Lung Injury Induced by Limb Ischemia/Reperfusion via Down-Regulating Chemerin and NLRP3 in Rats.
Topics: Acute Lung Injury; Animals; Blood Gas Analysis; Chemokines; Enzyme-Linked Immunosorbent Assay; Hydro | 2019 |
[Role of Rho/ROCK signaling pathway in the protective effects of hydrogen against acute lung injury in septic mice].
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Hydrogen; Inflamma | 2016 |
Quantitative proteomics reveals the mechanisms of hydrogen-conferred protection against hyperoxia-induced injury in type II alveolar epithelial cells.
Topics: Acute Lung Injury; Animals; Apoptosis; Cell Transdifferentiation; Chromatography, Liquid; Epithelial | 2018 |
Hydrogen-rich saline ameliorated LPS-induced acute lung injury via autophagy inhibition through the ROS/AMPK/mTOR pathway in mice.
Topics: Acute Lung Injury; AMP-Activated Protein Kinases; Animals; Autophagy; Blotting, Western; Bronchoalve | 2019 |
[The effect of hydrogen on hemorrhagic shock induced acute lung injury in rats].
Topics: Acute Lung Injury; Animals; Disease Models, Animal; Hydrogen; Interleukin-6; Lung; Male; Malondialde | 2013 |
Effects of three hydrogen-rich liquids on hemorrhagic shock in rats.
Topics: Acute Lung Injury; Animals; Hydrogen; Hydroxyethyl Starch Derivatives; Interleukin-10; Interleukin-6 | 2015 |
Combination therapy with nitric oxide and molecular hydrogen in a murine model of acute lung injury.
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Disease Models, An | 2015 |
Hydrogen inhalation protects against acute lung injury induced by hemorrhagic shock and resuscitation.
Topics: Acute Lung Injury; Administration, Inhalation; Animals; Fluid Therapy; Hydrogen; Male; Protective Ag | 2015 |
Saturated hydrogen saline attenuates endotoxin-induced lung dysfunction.
Topics: Acute Lung Injury; Animals; Apoptosis; Autophagy; Hydrogen; Lipid Peroxidation; Lipopolysaccharides; | 2015 |
[Effect of hydrogen-saline on lung injury and heme oxygenase-1 expression in the lung tissue of acute paraquat-intoxicated mice].
Topics: Acute Lung Injury; Animals; Heme Oxygenase-1; Hydrogen; Lung; Male; Malondialdehyde; Membrane Protei | 2015 |
Protective effect and mechanism of hydrogen treatment on lung epithelial barrier dysfunction in rats with sepsis.
Topics: Acute Lung Injury; Animals; Aquaporin 1; Epithelial Cells; Gene Expression Regulation; Hydrogen; Mal | 2016 |
Hydrogen Gas Inhalation Attenuates Seawater Instillation-Induced Acute Lung Injury via the Nrf2 Pathway in Rabbits.
Topics: Acute Lung Injury; Animals; Apoptosis; Cell Membrane Permeability; Epithelial Cells; Heme Oxygenase- | 2016 |
Consumption of hydrogen water reduces paraquat-induced acute lung injury in rats.
Topics: Acute Lung Injury; Animals; Apoptosis; Bronchoalveolar Lavage Fluid; Hydrogen; L-Lactate Dehydrogena | 2011 |
The effect of donor treatment with hydrogen on lung allograft function in rats.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Heme Oxygenase-1; Hydrogen; Lung; Lung Transpl | 2011 |
Hydrogen inhalation ameliorates lipopolysaccharide-induced acute lung injury in mice.
Topics: Acute Lung Injury; Administration, Inhalation; Animals; Antioxidants; Apoptosis; bcl-2-Associated X | 2011 |
Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and apoptosis.
Topics: Acute Lung Injury; Animals; Apoptosis; Cytokines; Hydrogen; Inflammation; Lipopolysaccharides; Lung; | 2012 |
Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and apoptosis.
Topics: Acute Lung Injury; Animals; Apoptosis; Cytokines; Hydrogen; Inflammation; Lipopolysaccharides; Lung; | 2012 |
Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and apoptosis.
Topics: Acute Lung Injury; Animals; Apoptosis; Cytokines; Hydrogen; Inflammation; Lipopolysaccharides; Lung; | 2012 |
Molecular hydrogen ameliorates lipopolysaccharide-induced acute lung injury in mice through reducing inflammation and apoptosis.
Topics: Acute Lung Injury; Animals; Apoptosis; Cytokines; Hydrogen; Inflammation; Lipopolysaccharides; Lung; | 2012 |
Hydrogen saline is protective for acute lung ischaemia/reperfusion injuries in rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acute Lung Injury; Animals; Biomarkers; Deoxyguanosine; Hydrogen; Male; | 2012 |
[Effect of hydrogen inhalation on p38 MAPK activation in rats with lipopolysaccharide- induced acute lung injury].
Topics: Acute Lung Injury; Administration, Inhalation; Animals; Hydrogen; Lipopolysaccharides; Lung; Male; p | 2012 |
Hydrogen inhalation decreases lung graft injury in brain-dead donor rats.
Topics: Acute Lung Injury; Animals; Antioxidants; Apoptosis; Brain Death; Caspase 1; Hydrogen; In Situ Nick- | 2013 |
Combined early fluid resuscitation and hydrogen inhalation attenuates lung and intestine injury.
Topics: Acute Lung Injury; Administration, Inhalation; Amine Oxidase (Copper-Containing); Animals; Combined | 2013 |