Page last updated: 2024-10-18

hydrogen and Acute Disease

hydrogen has been researched along with Acute Disease in 40 studies

Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.
dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.

Acute Disease: Disease having a short and relatively severe course.

Research Excerpts

ExcerptRelevanceReference
"To study the effect of hydrogen-rich water (HRW) on acute peritonitis with three different rat models."7.80Effect of hydrogen-rich water on acute peritonitis of rat models. ( Liu, C; Song, S; Tai, M; Wan, Y; Wu, Q; Zhang, J; Zhang, R, 2014)
" Ammonium and glucose productions from glutamine were inversely related to pHe and pHi in tubules from both control and acidotic animals and were higher in acidosis."7.68Regulation of glutamine metabolism in dog kidney cortex: effect of pH and chronic acidosis. ( Drewnowska, K; Schoolwerth, AC; Smith, BC, 1992)
"This study was designed to determine the effect of acute hyperventilation on distal nephron hydrogen ion secretion."7.65The effect of hyperventilation on distal nephron hydrogen ion secretion. ( Giammarco, RA; Goldstein, MB; Halperin, ML; Stinebaugh, BJ, 1976)
"Acute peritonitis has remained a fatal disease despite of recent advances in care and treatment, including antibiotic and anticoagulant treatments."5.62Peritoneal lavage with hydrogen-rich saline can be an effective and practical procedure for acute peritonitis. ( Egi, H; Hattori, M; Ide, K; Ohdan, H; Oue, N; Sada, H; Sawada, H; Sentani, K; Sumi, Y; Yasui, W, 2021)
"Hydrogen has been confirmed to have a protective role in various organs during pathological conditions and inflammation."5.51Molecular hydrogen accelerates the reversal of acute obstructive cholangitis‑induced liver dysfunction by restoring gap and tight junctions. ( Lin, W; Lu, B; Tang, H; Yu, J; Zhang, W; Zhu, Z, 2019)
"Hydrogen has been reported to have the ability to inhibit levels of cytokines such as TNF, IL-6 in vivo."5.39Hydrogen therapy may be an effective and specific novel treatment for acute graft-versus-host disease (GVHD). ( Qian, L; Shen, J, 2013)
"To study the effect of hydrogen-rich water (HRW) on acute peritonitis with three different rat models."3.80Effect of hydrogen-rich water on acute peritonitis of rat models. ( Liu, C; Song, S; Tai, M; Wan, Y; Wu, Q; Zhang, J; Zhang, R, 2014)
" Ammonium and glucose productions from glutamine were inversely related to pHe and pHi in tubules from both control and acidotic animals and were higher in acidosis."3.68Regulation of glutamine metabolism in dog kidney cortex: effect of pH and chronic acidosis. ( Drewnowska, K; Schoolwerth, AC; Smith, BC, 1992)
"This study was designed to determine the effect of acute hyperventilation on distal nephron hydrogen ion secretion."3.65The effect of hyperventilation on distal nephron hydrogen ion secretion. ( Giammarco, RA; Goldstein, MB; Halperin, ML; Stinebaugh, BJ, 1976)
"Hydrogen sulfide displays a dual role in the mechanism of AP according to its concentration in the system."2.50From nitric oxide to hyperbaric oxygen: invisible and subtle but nonnegligible gaseous signaling molecules in acute pancreatitis. ( Dong, DL; Iv, JC; Li, L; Sun, B; Wang, G; Wu, LF, 2014)
"Nine patients were affected by tetraplegia and 15 by paraplegia."1.62Small intestinal bacterial overgrowth in spinal cord injury patients. ( Antuori, A; Mearin, F; Serra, J; Vallès, M, 2021)
"Acute peritonitis has remained a fatal disease despite of recent advances in care and treatment, including antibiotic and anticoagulant treatments."1.62Peritoneal lavage with hydrogen-rich saline can be an effective and practical procedure for acute peritonitis. ( Egi, H; Hattori, M; Ide, K; Ohdan, H; Oue, N; Sada, H; Sawada, H; Sentani, K; Sumi, Y; Yasui, W, 2021)
"Hydrogen has been confirmed to have a protective role in various organs during pathological conditions and inflammation."1.51Molecular hydrogen accelerates the reversal of acute obstructive cholangitis‑induced liver dysfunction by restoring gap and tight junctions. ( Lin, W; Lu, B; Tang, H; Yu, J; Zhang, W; Zhu, Z, 2019)
"On univariate analysis, only the MPD stenosis was extracted as an independent factor (P = 0."1.48Increase in breath hydrogen concentration was correlated with the main pancreatic duct stenosis. ( Funasaka, K; Furukawa, K; Goto, H; Hirooka, Y; Iida, T; Ishigami, M; Ishikawa, T; Kawashima, H; Koya, T; Matsushita, M; Miyahara, R; Nakamura, M; Nishio, R; Ohno, E; Sakai, D; Shin, W; Suhara, H; Suzuki, H; Takeyama, T; Tanaka, H; Tsuruta, A; Uetsuki, K; Watanabe, O; Yamamura, T, 2018)
"Hydrogen has been reported to have the ability to inhibit levels of cytokines such as TNF, IL-6 in vivo."1.39Hydrogen therapy may be an effective and specific novel treatment for acute graft-versus-host disease (GVHD). ( Qian, L; Shen, J, 2013)
"In the surgical treatment of acute aortic dissection, intractable hemorrhage often occurs."1.30Application of AdvaSeal for acute aortic dissection: experimental study. ( Kawauchi, M; Kotsuka, Y; Ohtsuka, T; Takamoto, S; Tanaka, K, 1999)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199017 (42.50)18.7374
1990's8 (20.00)18.2507
2000's2 (5.00)29.6817
2010's11 (27.50)24.3611
2020's2 (5.00)2.80

Authors

AuthorsStudies
Vallès, M1
Antuori, A1
Mearin, F1
Serra, J1
Sada, H1
Egi, H1
Ide, K1
Sawada, H1
Sumi, Y1
Hattori, M1
Sentani, K1
Oue, N1
Yasui, W1
Ohdan, H1
Sakai, D1
Hirooka, Y1
Kawashima, H1
Ohno, E1
Ishikawa, T1
Suhara, H1
Takeyama, T1
Koya, T1
Tanaka, H1
Iida, T1
Nishio, R1
Suzuki, H1
Uetsuki, K1
Matsushita, M1
Yamamura, T1
Furukawa, K1
Funasaka, K1
Nakamura, M1
Miyahara, R1
Watanabe, O1
Ishigami, M1
Tsuruta, A1
Shin, W1
Goto, H1
Zhu, Z1
Yu, J2
Lin, W1
Tang, H1
Zhang, W1
Lu, B1
Qian, L2
Mei, K1
Shen, J2
Cai, J1
Shen, MH1
Cai, JM1
Sun, Q1
Zhang, DW1
Huo, ZL1
He, J1
Sun, XJ1
Wang, G2
Iv, JC1
Wu, LF1
Li, L1
Dong, DL1
Sun, B2
Zhang, J1
Wu, Q1
Song, S1
Wan, Y1
Zhang, R1
Tai, M1
Liu, C1
Shi, Q1
Liao, KS1
Zhao, KL1
Wang, WX1
Zuo, T1
Deng, WH1
Chen, C1
Guo, WY1
He, XB1
Abliz, A1
Wang, P1
Zhao, L1
Han, B1
Zhou, H1
Jia, G1
Wang, Y1
Song, Z1
Pan, S1
Bai, X1
Lv, J1
Ohta, S1
Wang, W1
Li, Y1
Ren, J1
Xia, F1
Li, J1
Zhang, Z1
Imbenotte, M1
Azaroual, N1
Cartigny, B1
Vermeersch, G1
Lhermitte, M1
Bondarenko, A1
Svichar, N1
Chesler, M1
Itoh, K1
Matsubara, T1
Nanki, M1
Nishimura, K1
Kambe, T1
Sugiyama, S1
Ozawa, T1
Sakamoto, N1
Schick, F1
Machens, HG1
Senninger, N1
Runkel, N1
Frank, G1
von Kummer, R1
Herfarth, C1
Paulson, WD1
Liu, X1
Nakano, I1
Ito, T1
Goto, M1
Migita, Y1
Furukawa, M1
Nawata, H1
Debnam, ES1
Denholm, EE1
Grimble, GK1
Tanaka, K1
Takamoto, S1
Ohtsuka, T1
Kotsuka, Y1
Kawauchi, M1
Giammarco, RA1
Goldstein, MB1
Halperin, ML1
Stinebaugh, BJ1
Nagata, K1
Watanabe, Y1
Adachi, J1
Watanabe, M1
Nohara, A1
Ritchie, WP1
Cherry, KJ1
Gibb, A1
Schoolwerth, AC1
Smith, BC1
Drewnowska, K1
Murphy, VA1
Johanson, CE1
Bates, TE1
Williams, SR2
Kauppinen, RA1
Gadian, DG2
Auffermann, W1
Camacho, SA1
Wu, S1
Litt, L1
Parmley, WW1
Higgins, CB1
Wikman-Coffelt, J1
Frackowiak, RS1
Crockard, HA1
Proctor, E1
Allen, K1
Russell, RW1
Gana, TJ1
Huhlewych, R1
Koo, J1
Stephensen, CB1
Sack, RB1
Sack, DA1
Juhler, M1
Himal, HS1
Boutros, M1
Weiser, M1
Ivey, KJ1
Smirnova, NA1
Granik, NP1
Schmitz, W1
Jennings, RB1
Skillman, JJ1
Gould, SA1
Chung, RS1
Silen, W1
Chertok, OM1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Hydrogen-Rich Celsior Solution Improve the Quality of Aging DBD Grafts in Liver/Kidney Transplantation: Prospective, Randomized Clinical Trial[NCT02613195]Phase 320 participants (Anticipated)Interventional2016-01-31Not yet recruiting
Assessment of the Clinical Importance of Insulin Resistance & Steroid-Associated Hyperglycemia in Relapsing Multiple Sclerosis[NCT03004079]160 participants (Anticipated)Observational2016-10-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for hydrogen and Acute Disease

ArticleYear
From nitric oxide to hyperbaric oxygen: invisible and subtle but nonnegligible gaseous signaling molecules in acute pancreatitis.
    Pancreas, 2014, Volume: 43, Issue:4

    Topics: Acute Disease; Animals; Carbon Monoxide; Gases; Humans; Hydrogen; Hydrogen Sulfide; Hyperbaric Oxyge

2014
Recent progress toward hydrogen medicine: potential of molecular hydrogen for preventive and therapeutic applications.
    Current pharmaceutical design, 2011, Volume: 17, Issue:22

    Topics: Acute Disease; Animals; Chronic Disease; Humans; Hydrogen; Oxidative Stress; Preventive Medicine; Re

2011
Acute haemorrhagic gastritis: modern concepts based on pathogenesis.
    Gut, 1971, Volume: 12, Issue:9

    Topics: Acute Disease; Aspirin; Blood Transfusion; Cell Membrane Permeability; Endoscopy; Gastrectomy; Gastr

1971

Other Studies

37 other studies available for hydrogen and Acute Disease

ArticleYear
Small intestinal bacterial overgrowth in spinal cord injury patients.
    Gastroenterologia y hepatologia, 2021, Volume: 44, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Aged; Blind Loop Syndrome; Breath Tests; Chronic Disease; Cross-Se

2021
Peritoneal lavage with hydrogen-rich saline can be an effective and practical procedure for acute peritonitis.
    Surgery today, 2021, Volume: 51, Issue:11

    Topics: Acute Disease; Animals; Antioxidants; Disease Models, Animal; Free Radical Scavengers; Hydrogen; Mal

2021
Increase in breath hydrogen concentration was correlated with the main pancreatic duct stenosis.
    Journal of breath research, 2018, 03-12, Volume: 12, Issue:3

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Breath Tests; Chronic Disease; Constriction, Patholog

2018
Molecular hydrogen accelerates the reversal of acute obstructive cholangitis‑induced liver dysfunction by restoring gap and tight junctions.
    Molecular medicine reports, 2019, Volume: 19, Issue:6

    Topics: Acute Disease; Alanine Transaminase; Animals; Aspartate Aminotransferases; Cholangitis; Connexins; D

2019
Administration of hydrogen-rich saline protects mice from lethal acute graft-versus-host disease (aGVHD).
    Transplantation, 2013, Mar-15, Volume: 95, Issue:5

    Topics: Acute Disease; Animals; Bone Marrow Transplantation; Cytokines; Female; Graft vs Host Disease; Hydro

2013
Neuroprotective effect of hydrogen-rich saline in acute carbon monoxide poisoning.
    CNS neuroscience & therapeutics, 2013, Volume: 19, Issue:5

    Topics: Acute Disease; Animals; Apoptosis; Carbon Monoxide Poisoning; Hydrogen; Neuroprotective Agents; Rats

2013
Hydrogen therapy may be an effective and specific novel treatment for acute graft-versus-host disease (GVHD).
    Journal of cellular and molecular medicine, 2013, Volume: 17, Issue:8

    Topics: Acute Disease; Animals; Cell Death; Down-Regulation; Graft vs Host Disease; Hydrogen; Mice; Models,

2013
Effect of hydrogen-rich water on acute peritonitis of rat models.
    International immunopharmacology, 2014, Volume: 21, Issue:1

    Topics: Acute Disease; Animals; Cecum; Disease Models, Animal; Endotoxins; Feces; Humans; Hydrogen; Interleu

2014
Hydrogen-rich saline attenuates acute renal injury in sodium taurocholate-induced severe acute pancreatitis by inhibiting ROS and NF-κB pathway.
    Mediators of inflammation, 2015, Volume: 2015

    Topics: Acute Disease; Acute Kidney Injury; Amylases; Animals; Cytokines; Hydrogen; Kidney; Male; Neutrophil

2015
MAPKs and Hsc70 are critical to the protective effect of molecular hydrogen during the early phase of acute pancreatitis.
    The FEBS journal, 2016, Volume: 283, Issue:4

    Topics: Acute Disease; Animals; Cell Line; Disease Models, Animal; HSC70 Heat-Shock Proteins; Hydrogen; Mice

2016
Hydrogen rich saline reduces immune-mediated brain injury in rats with acute carbon monoxide poisoning.
    Neurological research, 2012, Volume: 34, Issue:10

    Topics: Acute Disease; Animals; Brain Injuries; Carbon Monoxide Poisoning; Hydrogen; Male; Neuroprotective A

2012
Detection and quantitation of xenobiotics in biological fluids by 1H NMR spectroscopy.
    Journal of toxicology. Clinical toxicology, 2003, Volume: 41, Issue:7

    Topics: Acute Disease; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Paraquat; Poisoning; Salicylates;

2003
Role of Na+-H+ and Na+-Ca2+ exchange in hypoxia-related acute astrocyte death.
    Glia, 2005, Jan-01, Volume: 49, Issue:1

    Topics: Acute Disease; Animals; Astrocytes; Brain; Calcium; Calcium Signaling; Cell Death; Cell Hypoxia; Cel

2005
Relationship between regional myocardial blood flow and tissue ATP content in acute ischemia.
    Japanese heart journal, 1984, Volume: 25, Issue:4

    Topics: Acute Disease; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Disease; Dogs; Electr

1984
The distribution of the magnetic field in the spine depends on the composition of bone marrow.
    Journal of magnetic resonance. Series B, 1995, Volume: 108, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Body Water; Bone Marrow; Bone Marrow Transplantation; Electron Spi

1995
Is the hydrogen clearance technique a useful tool for measurements of pancreatic blood flow during acute experimental pancreatitis?
    Pancreas, 1993, Volume: 8, Issue:1

    Topics: Acute Disease; Animals; Blood Flow Velocity; Dogs; Evaluation Studies as Topic; Hemodynamics; Hydrog

1993
Effect of acute pH change on serum anion gap.
    Journal of the American Society of Nephrology : JASN, 1996, Volume: 7, Issue:2

    Topics: Acid-Base Imbalance; Acute Disease; Animals; Anions; Bicarbonates; Carbon Dioxide; Dogs; Hydrogen; H

1996
Measurement of pancreatic blood flow with the intraductal electrode method of the hydrogen clearance technique in acute pancreatitis in rats.
    Pancreas, 1996, Volume: 13, Issue:3

    Topics: Acute Disease; Amylases; Animals; Blood Flow Velocity; Blood Pressure; Ceruletide; Electrodes; Hemat

1996
Acute and chronic exposure of rat intestinal mucosa to dextran promotes SGLTI-mediated glucose transport.
    European journal of clinical investigation, 1998, Volume: 28, Issue:8

    Topics: Acute Disease; Animals; Anticoagulants; Biological Transport; Body Weight; Chromatography, High Pres

1998
Application of AdvaSeal for acute aortic dissection: experimental study.
    The Annals of thoracic surgery, 1999, Volume: 68, Issue:4

    Topics: Acute Disease; Animals; Aorta, Thoracic; Aortic Aneurysm, Thoracic; Aortic Dissection; Dogs; Hydroge

1999
The effect of hyperventilation on distal nephron hydrogen ion secretion.
    The Journal of clinical investigation, 1976, Volume: 58, Issue:1

    Topics: Acute Disease; Animals; Carbon Dioxide; Carbonic Anhydrases; Hydrogen; Hydrogen-Ion Concentration; H

1976
[Pancreatic local blood flow in experimental acute pancreatitis (author's transl)].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1979, Volume: 76, Issue:10

    Topics: Acute Disease; Animals; Hydrogen; Male; Pancreas; Pancreatitis; Plethysmography; Rats; Regional Bloo

1979
Influence of methylprednisolone sodium succinate on bile-acid-induced acute gastric mucosal damage.
    Surgery, 1978, Volume: 84, Issue:2

    Topics: Acute Disease; Administration, Topical; Aminopyrine; Animals; Bile Acids and Salts; Dogs; Gastric Mu

1978
Regulation of glutamine metabolism in dog kidney cortex: effect of pH and chronic acidosis.
    The American journal of physiology, 1992, Volume: 262, Issue:6 Pt 2

    Topics: Acidosis; Acute Disease; Ammonia; Animals; Chronic Disease; Dogs; Glucose; Glutamine; Hydrogen; Hydr

1992
Na(+)-H+ exchange in choroid plexus and CSF in acute metabolic acidosis or alkalosis.
    The American journal of physiology, 1990, Volume: 258, Issue:6 Pt 2

    Topics: Acid-Base Equilibrium; Acidosis; Acute Disease; Alkalosis; Amiloride; Animals; Antipyrine; Arteries;

1990
Observation of cerebral metabolites in an animal model of acute liver failure in vivo: a 1H and 31P nuclear magnetic resonance study.
    Journal of neurochemistry, 1989, Volume: 53, Issue:1

    Topics: Acute Disease; Animals; Biomarkers; Brain; Glutamates; Glutamic Acid; Glutamine; Hydrogen; Lactates;

1989
31P and 1H magnetic resonance spectroscopy of acute alcohol cardiac depression in rats.
    Magnetic resonance in medicine, 1988, Volume: 8, Issue:1

    Topics: Acute Disease; Animals; Chromatography, High Pressure Liquid; Coronary Circulation; Depression, Chem

1988
Acute cerebral ischaemia: concurrent changes in cerebral blood flow, energy metabolites, pH, and lactate measured with hydrogen clearance and 31P and 1H nuclear magnetic resonance spectroscopy. I. Methodology.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1987, Volume: 7, Issue:2

    Topics: Acute Disease; Animals; Brain Ischemia; Cerebrovascular Circulation; Energy Metabolism; Gerbillinae;

1987
Focal gastric mucosal blood flow in aspirin-induced ulceration.
    Annals of surgery, 1987, Volume: 205, Issue:4

    Topics: Acute Disease; Animals; Aspirin; Dogs; Electrodes; Female; Gastric Mucosa; Hydrogen; Ischemia; Male;

1987
Comparison of noninvasive breath hydrogen test for gastric acid secretion to standard intubation test in infants and young children.
    Digestive diseases and sciences, 1987, Volume: 32, Issue:9

    Topics: Acute Disease; Betazole; Breath Tests; Child, Preschool; Diarrhea; Evaluation Studies as Topic; Fema

1987
Simultaneous determination of regional cerebral blood flow, glucose metabolism, and pH in acute experimental allergic encephalomyelitis.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1987, Volume: 7, Issue:5

    Topics: Acute Disease; Animals; Autoradiography; Cerebrovascular Circulation; Encephalomyelitis; Glucose; Gu

1987
The relationship between bile and hydrochloric acid in the pathogenesis of acute gastric erosions.
    The American journal of gastroenterology, 1974, Volume: 62, Issue:5

    Topics: Acid Phosphatase; Acute Disease; Animals; Bile; Cathepsins; Chlorides; Dogs; Female; Fucose; Gastric

1974
[Remote after-effects of acute occupational lesions of the respiratory tract caused by irritating gases].
    Gigiena truda i professional'nye zabolevaniia, 1971, Volume: 15, Issue:11

    Topics: Acute Disease; Adult; Ammonia; Chlorine; Environmental Exposure; Female; Follow-Up Studies; Formalde

1971
[Triggering and manifestation of psychomotor seizures in a previously brain-damaged boy through acute poisoning of liquid manure gases].
    Zeitschrift fur die gesamte Hygiene und ihre Grenzgebiete, 1971, Volume: 17, Issue:8

    Topics: Accidents; Acute Disease; Adolescent; Agricultural Workers' Diseases; Electroencephalography; Enviro

1971
Early phase of myocardial ischemic injury and infarction.
    The American journal of cardiology, 1969, Volume: 24, Issue:6

    Topics: Acute Disease; Animals; Arrhythmias, Cardiac; Dogs; Glycogen; Histocytochemistry; Humans; Hydrogen;

1969
The gastric mucosal barrier: clinical and experimental studies in critically ill and normal man, and in the rabbit.
    Annals of surgery, 1970, Volume: 172, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Aged; Animals; Biological Transport; Blood Transfusion; Female; Ga

1970
[Acute hydrogen sulfide poisoning].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1968, Volume: 68, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Autonomic Nervous System; Body Temperature; Chemical Industry; Ele

1968