hydrochlorothiazide has been researched along with Syndrome in 24 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
Syndrome: A characteristic symptom complex.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors made an open-comparative trial of fosinopril (Fosinorm) efficacy and tolerability in 20 patients (9 males and 11 females) with stage II mild and moderate essential hypertension accompanied with disturbed glucose tolerance and dyslipidemia." | 5.08 | [Fosinorm in the treatment of essential hypertension with a metabolic syndrome]. ( Drozdov, VN; Ivleva, AIa; Kobalava, ZhD; Kotovskaia, IuV; Moiseev, VS; Moryleva, ON, 1997) |
| "Thiazide doses equivalent to 1 to 2 mg/kg/d of hydrochlorothiazide (HCTZ) have been proposed to correct hypercalciuria and prevent kidney failure in patients with Dent disease." | 3.74 | Effect of hydrochlorothiazide on urinary calcium excretion in dent disease: an uncontrolled trial. ( Azizi, M; Baudouin, V; Blanchard, A; Boudailliez, B; Charbit, M; Deschesnes, G; Ezzhair, N; Loirat, C; Macher, MA; Mogenet, A; Niaudet, P; Peyrard, S; Vargas-Poussou, R, 2008) |
| "Eleven patients with Gitelman's syndrome and 23 controls underwent acute administration of the thiazide diuretic hydrochlorothiazide and/or the loop diuretic furosemide (FUR) in order to indirectly evaluate the activity of the two electroneutral Na+/Cl(-)-reabsorptive systems of the distal nephron, namely the thiazide-sensitive Na+-Cl- symporter of the distal convoluted tubule and the FUR-sensitive Na+-K+-2Cl- symporter of the loop of Henle." | 3.69 | Abnormal reabsorption of Na+/CI- by the thiazide-inhibitable transporter of the distal convoluted tubule in Gitelman's syndrome. ( Brunati, C; Colussi, G; De Ferrari, ME; Rombolà, G, 1997) |
| "The differential diagnosis of pulmonary disease should include drug toxicity, progression of the primary illness, and opportunistic infection." | 2.42 | Infiltrative lung disease due to noncytotoxic agents. ( Cooper, JA; Eggert, M; Lock, BJ, 2004) |
| "We describe a patient with diabetic nephropathy and proteinuria who developed a remarkable hyperkalaemia on treatment with an angiotensin-receptor blocker." | 1.34 | Treating proteinuria in a diabetic patient despite hyperkalaemia due to hyporeninaemic hypoaldosteronism. ( Bolk, JH; Ijpelaar, DH; van Nieuwkoop, C, 2007) |
| "Gitelman's syndrome is an important differential diagnosis in the evaluation of the normotensive patient with hypokalemia." | 1.32 | [Gitelman's syndrome: an important differential diagnosis of hypokalemia]. ( Grabensee, B; Heering, P; Kurschat, C, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (54.17) | 18.7374 |
| 1990's | 3 (12.50) | 18.2507 |
| 2000's | 7 (29.17) | 29.6817 |
| 2010's | 1 (4.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blanchard, A | 1 |
| Vargas-Poussou, R | 1 |
| Peyrard, S | 1 |
| Mogenet, A | 1 |
| Baudouin, V | 1 |
| Boudailliez, B | 1 |
| Charbit, M | 1 |
| Deschesnes, G | 1 |
| Ezzhair, N | 1 |
| Loirat, C | 1 |
| Macher, MA | 1 |
| Niaudet, P | 1 |
| Azizi, M | 1 |
| Paulais, M | 1 |
| Bloch-Faure, M | 1 |
| Picard, N | 1 |
| Jacques, T | 1 |
| Ramakrishnan, SK | 1 |
| Keck, M | 1 |
| Sohet, F | 1 |
| Eladari, D | 1 |
| Houillier, P | 1 |
| Lourdel, S | 1 |
| Teulon, J | 1 |
| Tucker, SJ | 1 |
| Kurschat, C | 1 |
| Heering, P | 1 |
| Grabensee, B | 1 |
| AMERIO, A | 1 |
| LEONDEFF, I | 1 |
| CORATELLI, P | 1 |
| CURATOLI, L | 1 |
| GOMEZ, RE | 1 |
| PRIETO, ME | 1 |
| BRADFORD, I | 1 |
| GENERINI, G | 1 |
| GROSSI, F | 1 |
| GILBERT-DREYFUS, M | 1 |
| BRONZINI, A | 1 |
| GATTI, A | 1 |
| SCOTTI, G | 1 |
| Lock, BJ | 1 |
| Eggert, M | 1 |
| Cooper, JA | 1 |
| Leonova, MV | 1 |
| Demidova, MA | 1 |
| Tarasov, AV | 1 |
| Belousov, IuB | 1 |
| van Nieuwkoop, C | 1 |
| Ijpelaar, DH | 1 |
| Bolk, JH | 1 |
| Colussi, G | 1 |
| Rombolà, G | 1 |
| Brunati, C | 1 |
| De Ferrari, ME | 1 |
| Kobalava, ZhD | 1 |
| Kotovskaia, IuV | 1 |
| Moryleva, ON | 1 |
| Drozdov, VN | 1 |
| Ivleva, AIa | 1 |
| Moiseev, VS | 1 |
| Burgess, HK | 1 |
| Jayawardene, SA | 1 |
| Velasco, N | 1 |
| Bald, M | 1 |
| Vester, U | 1 |
| Wingen, AM | 1 |
| Ramenghi, M | 1 |
| Forti, M | 1 |
| Teodori, G | 1 |
| Isenring, P | 1 |
| Lebel, M | 1 |
| Grose, JH | 1 |
| Martínez Agulló, E | 1 |
| Gallego Gómez, J | 1 |
| Jiménez Cruz, FJ | 1 |
| Pasman, JW | 1 |
| Gabreëls, FJ | 1 |
| Semmekrot, B | 1 |
| Renier, WO | 1 |
| Monnens, LA | 1 |
| Rodríguez-Soriano, J | 1 |
| Vallo, A | 1 |
| Domínguez, MJ | 1 |
| Ford, SM | 1 |
| Lumpkin, HL | 1 |
| Margolis, BL | 1 |
| Lifschitz, MD | 1 |
| Mohr, JP | 1 |
| Sridhar, CB | 1 |
| Calvert, GD | 1 |
| Ibbertson, HK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacodynamic Evaluation of the ANTICALCIURIC Effect of Hydrochlorothiazide in Dent's Disease[NCT00638482] | Phase 2/Phase 3 | 10 participants (Actual) | Interventional | 2003-07-31 | Terminated (stopped due to terminated) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for hydrochlorothiazide and Syndrome
| Article | Year |
|---|---|
[2 IMPORTANT SIDE-EFFECTS OF SALURETIC DRUGS: HYPERURICEMIC AND HYPERGLYCEMIC SYNDROMES].
Topics: Acetazolamide; Blood Chemical Analysis; Chlorothiazide; Chlorthalidone; Diuretics; Humans; Hydrochlo | 1963 |
Infiltrative lung disease due to noncytotoxic agents.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Aspirin; Humans; Hydrochlorothiazide; | 2004 |
2 trials available for hydrochlorothiazide and Syndrome
| Article | Year |
|---|---|
[Fosinorm in the treatment of essential hypertension with a metabolic syndrome].
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Chronic Disease; Diuretics; Drug | 1997 |
[Medical treatment of the prostatism syndrome. Comparative study].
Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Drug Evaluation; Humans; Hyd | 1987 |
20 other studies available for hydrochlorothiazide and Syndrome
| Article | Year |
|---|---|
Effect of hydrochlorothiazide on urinary calcium excretion in dent disease: an uncontrolled trial.
Topics: Adolescent; Calcium; Child; Diuretics; Humans; Hydrochlorothiazide; Hypercalciuria; Hypophosphatemia | 2008 |
Renal phenotype in mice lacking the Kir5.1 (Kcnj16) K+ channel subunit contrasts with that observed in SeSAME/EAST syndrome.
Topics: Acidosis; Amiloride; Animals; Diuretics; Furosemide; Humans; Hydrochlorothiazide; Hypokalemia; Kidne | 2011 |
[Gitelman's syndrome: an important differential diagnosis of hypokalemia].
Topics: Adult; Alkalosis; Calcium; Carrier Proteins; Diagnosis, Differential; Diuretics; Fatigue; Female; Fu | 2003 |
[RESEARCH ON THE DIURETIC AND SALURETIC ACTIVITY OF TRIAMTERENE IN THE THERAPY OF EDEMATIGENOUS SYNDROMES].
Topics: Diuretics; Edema; Glomerulonephritis; Heart Diseases; Heart Failure; Hydrochlorothiazide; Liver Cirr | 1963 |
[A TEST FOR DIFFERENTIAL DIAGNOSIS OF POLYURIC SYNDROME. ITS SPECIFICITY IN DIABETES INSIPIDUS].
Topics: Diabetes Insipidus; Diagnosis, Differential; Genetics, Medical; Glycosuria; Humans; Hydrochlorothiaz | 1963 |
[POLYURODIPSIC SYNDROMES].
Topics: Chlorothiazide; Diabetes Insipidus; Diabetes Insipidus, Neurogenic; Diagnosis; Diagnosis, Differenti | 1964 |
[COMBINATION OF TRIAMINOPTERIDINE AND HYDROCHLOROTHIAZIDE IN THE THERAPY OF EDEMA SYNDROMES IN THE AGED].
Topics: Aged; Drug Therapy; Edema; Geriatrics; Humans; Hydrochlorothiazide; Syndrome; Triamterene | 1964 |
[Hypotensive, organoprotective, and metabolic effects of Angiotensin converting enzyme inhibitor moexipril in women with postmenopausal syndrome].
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Delayed-Action Preparations; | 2006 |
Treating proteinuria in a diabetic patient despite hyperkalaemia due to hyporeninaemic hypoaldosteronism.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Diabetes Mellitus, Type 2; Diabet | 2007 |
Abnormal reabsorption of Na+/CI- by the thiazide-inhibitable transporter of the distal convoluted tubule in Gitelman's syndrome.
Topics: Adolescent; Adult; Bartter Syndrome; Carrier Proteins; Case-Control Studies; Diuretics; Female; Furo | 1997 |
Dent's disease: can we slow its progression?
Topics: Adolescent; Calcium; Disease Progression; Female; Humans; Hydrochlorothiazide; Hypophosphatemia; Kid | 2001 |
Dent's disease.
Topics: Calcium; Diuretics; Humans; Hydrochlorothiazide; Hypokalemia; Kidney Diseases; Kidney Failure, Chron | 2002 |
[Renal idiopathic acidosis (type Albright) in 2 sisters with familial nephro-malformations. Studies on administration of hydrochlorothiazide].
Topics: Acidosis, Renal Tubular; Child; Child, Preschool; Female; Humans; Hydrochlorothiazide; Kidney; Syndr | 1976 |
Endocrine sodium and volume regulation in familial hyperkalemia with hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Family; Female; Humans; Hydrochloroth | 1992 |
Hyperkalemic periodic paralysis in Gordon's syndrome: a possible defect in atrial natriuretic peptide function.
Topics: Adolescent; Atrial Natriuretic Factor; Humans; Hydrochlorothiazide; Hyperkalemia; Hypertension; Male | 1989 |
"Chloride-shunt" syndrome: an overlooked cause of renal hypercalciuria.
Topics: Atrial Natriuretic Factor; Calcium; Chlorides; Humans; Hydrochlorothiazide; Infant; Kidney; Kidney D | 1989 |
Transient vasopressin-resistant diabetes insipidus of pregnancy.
Topics: Adult; Deamino Arginine Vasopressin; Diabetes Insipidus; Drug Resistance; Female; Humans; Hydrochlor | 1986 |
The Spitzer-Weinstein syndrome: one form of type IV renal tubular acidosis and its response to hydrochlorothiazide.
Topics: Acidosis, Renal Tubular; Child; Electrolytes; Female; Growth Disorders; Humans; Hydrochlorothiazide; | 1986 |
Lacunar stroke.
Topics: Adult; Blood Pressure; Brain; Cerebrovascular Disorders; Diagnosis, Differential; Hemiplegia; Humans | 1986 |
Syndrome of hypernatremia, hypodipsia and partial diabetes insipidus: a new interpretation.
Topics: Adolescent; Chlorpropamide; Diabetes Insipidus; Drinking; Female; Humans; Hydrochlorothiazide; Hyper | 1974 |