Page last updated: 2024-10-28

hydrochlorothiazide and Stroke

hydrochlorothiazide has been researched along with Stroke in 29 studies

Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.

Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)

Research Excerpts

ExcerptRelevanceReference
" The aim of this study was to elucidate whether hydrochlorothiazide additionally exerts such effects in stroke patients under treatment with losartan."9.20Effects of hydrochlorothiazide on oxidative stress and pulse pressure in hypertensive patients with chronic stroke: the EMINENT study. ( Ago, T; Hata, J; Ibayashi, S; Kamouchi, M; Kitazono, T; Kusuda, K; Nagao, T; Nakane, H; Omae, T, 2015)
"The aim of this study was to test the hypothesis that the angiotensin II type 1 receptor blocker (ARB) candesartan can reduce the risk of stroke in elderly patients with isolated systolic hypertension (ISH)."9.11Stroke prevention with the angiotensin II type 1-receptor blocker candesartan in elderly patients with isolated systolic hypertension: the Study on Cognition and Prognosis in the Elderly (SCOPE). ( Elmfeldt, D; Farsang, C; Hofman, A; Lithell, H; Olofsson, B; Papademetriou, V; Skoog, I; Trenkwalder, P; Zanchetti, A, 2004)
"To test the hypothesis that losartan improves outcome better than atenolol in patients with isolated systolic hypertension and electrocardiographically documented left ventricular hypertrophy (ECG-LVH)."9.10Effects of losartan on cardiovascular morbidity and mortality in patients with isolated systolic hypertension and left ventricular hypertrophy: a Losartan Intervention for Endpoint Reduction (LIFE) substudy. ( Aurup, P; Beevers, G; Dahlöf, B; de Faire, U; Devereux, RB; Edelman, J; Fyhrquist, F; Ibsen, H; Julius, S; Kjeldsen, SE; Kristianson, K; Lederballe-Pedersen, O; Lindholm, LH; Nieminen, MS; Omvik, P; Oparil, S; Snapinn, S; Wedel, H, 2002)
"The vascular protective effects of placebo, candesartan (1 mg kg(-1) per day) monotherapy, candesartan (1 mg kg(-1) per day) and amlodipine (1 mg kg(-1) per day) combination therapy, and candesartan (1 mg kg(-1) per day) and hydrochlorothiazide (HCTZ) (10 mg kg(-1) per day) combination therapy for 2 weeks were compared in stroke-prone, spontaneously hypertensive rats."7.77Candesartan and amlodipine combination therapy provides powerful vascular protection in stroke-prone spontaneously hypertensive rats. ( Jin, D; Miyazaki, M; Sakonjo, H; Shimosato, T; Takai, S, 2011)
" Therefore, olmesartan, an angiotensin type 1 receptor blocker, might affect oxidative stress in the brains of stroke-prone spontaneously hypertensive rats (SHRSP)."7.75Olmesartan reduces oxidative stress in the brain of stroke-prone spontaneously hypertensive rats assessed by an in vivo ESR method. ( Araki, S; Hirooka, Y; Kishi, T; Sunagawa, K; Utsumi, H; Yasukawa, K, 2009)
"Compared with untreated controls, omapatrilat and I + H significantly attenuated hypertension [male control, 198."7.72Comparison of the effects of omapatrilat and irbesartan/hydrochlorothiazide on endothelial function and cardiac hypertrophy in the stroke-prone spontaneously hypertensive rat: sex differences. ( Beattie, E; Dominiczak, AF; Graham, D; Hamilton, C; Spiers, A, 2004)
"Treatment with losartan (+/- HCTZ) was well tolerated and led to a substantial decrease in blood pressure and associated stroke risk."6.73Impact of losartan on stroke risk in hypertensive patients in primary care. ( Bestehorn, K; Wahle, K, 2007)
"Losartan/HCTZ is an effective combination therapy, lowering blood pressure (BP) to a greater extent than losartan or HCTZ alone in patients with hypertension."6.45Losartan/Hydrochlorothiazide: a review of its use in the treatment of hypertension and for stroke risk reduction in patients with hypertension and left ventricular hypertrophy. ( Keating, GM, 2009)
"Losartan was frequently administered with hydrochlorothiazide in the Losartan Intervention For Endpoint reduction in hypertension (LIFE) study, in which there was a 25% risk reduction for stroke in the losartan-based compared with the atenolol-based treatment group."6.44Fixed combination of losartan and hydrochlorothiazide and reduction of risk of stroke. ( Høieggen, A; Kizer, JR; Kjeldsen, SE; Lyle, PA; Oparil, S; Os, I, 2007)
" The Avoiding Cardiovascular Events Through Combination Therapy in Patients Living With Systolic Hypertension (ACCOMPLISH) trial showed that the combination of benazepril+amlodipine (B+A) is superior to benazepril+hydrochlorothiazide (B+H) in reducing CV events."5.20Amlodipine+benazepril is superior to hydrochlorothiazide+benazepril irrespective of baseline pulse pressure: subanalysis of the ACCOMPLISH trial. ( Asp, J; Dahlöf, B; Jamerson, KA; Jia, Y; Kjeldsen, SE; Östergren, J; Skoglund, PH; Svensson, P; Weber, MA; Zappe, DH, 2015)
" The aim of this study was to elucidate whether hydrochlorothiazide additionally exerts such effects in stroke patients under treatment with losartan."5.20Effects of hydrochlorothiazide on oxidative stress and pulse pressure in hypertensive patients with chronic stroke: the EMINENT study. ( Ago, T; Hata, J; Ibayashi, S; Kamouchi, M; Kitazono, T; Kusuda, K; Nagao, T; Nakane, H; Omae, T, 2015)
"The aim of this study was to test the hypothesis that the angiotensin II type 1 receptor blocker (ARB) candesartan can reduce the risk of stroke in elderly patients with isolated systolic hypertension (ISH)."5.11Stroke prevention with the angiotensin II type 1-receptor blocker candesartan in elderly patients with isolated systolic hypertension: the Study on Cognition and Prognosis in the Elderly (SCOPE). ( Elmfeldt, D; Farsang, C; Hofman, A; Lithell, H; Olofsson, B; Papademetriou, V; Skoog, I; Trenkwalder, P; Zanchetti, A, 2004)
"To test the hypothesis that losartan improves outcome better than atenolol in patients with isolated systolic hypertension and electrocardiographically documented left ventricular hypertrophy (ECG-LVH)."5.10Effects of losartan on cardiovascular morbidity and mortality in patients with isolated systolic hypertension and left ventricular hypertrophy: a Losartan Intervention for Endpoint Reduction (LIFE) substudy. ( Aurup, P; Beevers, G; Dahlöf, B; de Faire, U; Devereux, RB; Edelman, J; Fyhrquist, F; Ibsen, H; Julius, S; Kjeldsen, SE; Kristianson, K; Lederballe-Pedersen, O; Lindholm, LH; Nieminen, MS; Omvik, P; Oparil, S; Snapinn, S; Wedel, H, 2002)
"To evaluate the efficacy and safety of the polypill for prevention of cardiovascular disease (CVD) and stroke and to present literature related to the polypill components (statin, aspirin, antihypertensive) for primary prevention of CVD and stroke."4.88A polypill for all? Critical review of the polypill literature for primary prevention of cardiovascular disease and stroke. ( Carey, KM; Comee, MR; Donovan, JL; Kanaan, AO, 2012)
"The vascular protective effects of placebo, candesartan (1 mg kg(-1) per day) monotherapy, candesartan (1 mg kg(-1) per day) and amlodipine (1 mg kg(-1) per day) combination therapy, and candesartan (1 mg kg(-1) per day) and hydrochlorothiazide (HCTZ) (10 mg kg(-1) per day) combination therapy for 2 weeks were compared in stroke-prone, spontaneously hypertensive rats."3.77Candesartan and amlodipine combination therapy provides powerful vascular protection in stroke-prone spontaneously hypertensive rats. ( Jin, D; Miyazaki, M; Sakonjo, H; Shimosato, T; Takai, S, 2011)
"There is significant controversy around whether chlorthalidone (CTD) is superior to hydrochlorothiazide (HCTZ) in hypertension management."3.77Chlorthalidone reduces cardiovascular events compared with hydrochlorothiazide: a retrospective cohort analysis. ( Bleske, BE; Dorsch, MP; Erickson, SR; Gillespie, BW; Weder, AB, 2011)
" Therefore, olmesartan, an angiotensin type 1 receptor blocker, might affect oxidative stress in the brains of stroke-prone spontaneously hypertensive rats (SHRSP)."3.75Olmesartan reduces oxidative stress in the brain of stroke-prone spontaneously hypertensive rats assessed by an in vivo ESR method. ( Araki, S; Hirooka, Y; Kishi, T; Sunagawa, K; Utsumi, H; Yasukawa, K, 2009)
"A total of 500 outpatients with primary AH and risk factors including the risk of stroke received Hyzaar (losartan 50/100 mg and hydrochlorthiaside 12."3.75[Treatment of patients with arterial hypertension and other stroke risk factors in clinical practice. The PROGNOS program]. ( Bubnova, MG; Oganov, RG, 2009)
"Compared with untreated controls, omapatrilat and I + H significantly attenuated hypertension [male control, 198."3.72Comparison of the effects of omapatrilat and irbesartan/hydrochlorothiazide on endothelial function and cardiac hypertrophy in the stroke-prone spontaneously hypertensive rat: sex differences. ( Beattie, E; Dominiczak, AF; Graham, D; Hamilton, C; Spiers, A, 2004)
"Treatment with losartan (+/- HCTZ) was well tolerated and led to a substantial decrease in blood pressure and associated stroke risk."2.73Impact of losartan on stroke risk in hypertensive patients in primary care. ( Bestehorn, K; Wahle, K, 2007)
"Losartan/HCTZ is an effective combination therapy, lowering blood pressure (BP) to a greater extent than losartan or HCTZ alone in patients with hypertension."2.45Losartan/Hydrochlorothiazide: a review of its use in the treatment of hypertension and for stroke risk reduction in patients with hypertension and left ventricular hypertrophy. ( Keating, GM, 2009)
"Losartan was frequently administered with hydrochlorothiazide in the Losartan Intervention For Endpoint reduction in hypertension (LIFE) study, in which there was a 25% risk reduction for stroke in the losartan-based compared with the atenolol-based treatment group."2.44Fixed combination of losartan and hydrochlorothiazide and reduction of risk of stroke. ( Høieggen, A; Kizer, JR; Kjeldsen, SE; Lyle, PA; Oparil, S; Os, I, 2007)
" The drug's effect as well as adverse effects should be actively sought, and dosage alterations made in order to enhance the drug's effect."1.32Introduction to monitoring. What is what you prescribed actually doing? ( George, A; Shakib, S, 2003)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's20 (68.97)29.6817
2010's9 (31.03)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Skoglund, PH1
Svensson, P1
Asp, J1
Dahlöf, B3
Kjeldsen, SE4
Jamerson, KA1
Weber, MA3
Jia, Y2
Zappe, DH2
Östergren, J1
Nakane, H1
Kamouchi, M1
Hata, J1
Ibayashi, S1
Kusuda, K1
Omae, T1
Nagao, T1
Ago, T1
Kitazono, T1
Wald, NJ2
Luteijn, JM2
Morris, JK2
Taylor, D1
Oppenheimer, P1
Keating, GM1
Araki, S1
Hirooka, Y1
Kishi, T1
Yasukawa, K1
Utsumi, H1
Sunagawa, K1
Bubnova, MG1
Oganov, RG1
Takai, S1
Jin, D1
Shimosato, T1
Sakonjo, H1
Miyazaki, M1
Dorsch, MP1
Gillespie, BW1
Erickson, SR1
Bleske, BE1
Weder, AB1
Carey, KM1
Comee, MR1
Donovan, JL1
Kanaan, AO1
Julius, S2
Brunner, HR1
Hua, TA1
McInnes, GT1
Schork, A1
Mancia, G1
Zanchetti, A4
Devereux, RB1
Aurup, P1
Edelman, J1
Beevers, G1
de Faire, U1
Fyhrquist, F1
Ibsen, H1
Kristianson, K1
Lederballe-Pedersen, O1
Lindholm, LH1
Nieminen, MS1
Omvik, P1
Oparil, S2
Snapinn, S1
Wedel, H1
Baumgart, P1
Shakib, S1
George, A1
Graham, D1
Hamilton, C1
Beattie, E1
Spiers, A1
Dominiczak, AF1
Staessen, JA1
Thijisq, L1
Fagard, R1
Celis, H1
Birkenhäger, WH1
Bulpitt, CJ1
de Leeuw, PW1
Fletcher, AE1
Forette, F1
Leonetti, G1
McCormack, P1
Nachev, C1
O'Brien, E1
Rodicio, JL1
Rosenfeld, J1
Sarti, C1
Tuomilehto, J1
Webster, J1
Yodfat, Y1
Williams, B1
Papademetriou, V1
Farsang, C1
Elmfeldt, D1
Hofman, A1
Lithell, H1
Olofsson, B1
Skoog, I1
Trenkwalder, P1
Liu, L1
Zhang, Y1
Liu, G1
Li, W1
Zhang, X1
Cooper-Dehoff, R1
Cohen, JD1
Bakris, GL2
Messerli, FH2
Erdine, S1
Hewkin, AC1
Kupfer, S1
Pepine, CJ2
Bestehorn, K1
Wahle, K1
Pitt, B1
Velazquez, E1
Gupte, J1
Lefkowitz, M1
Hester, A1
Shi, V1
Weir, M1
Kjeldsen, S1
Massie, B1
Nesbitt, S1
Ofili, E1
Jamerson, K1
Soucek, M1
Plachý, M1
Lyle, PA1
Kizer, JR1
Høieggen, A1
Os, I1
Coca, A1
Benetos, A1
Zhou, Q1
Champion, A1
Cooper-DeHoff, RM1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Pilot Study of Cardiac Magnetic Resonance in Patients With Muscular Dystrophy[NCT02921321]100 participants (Anticipated)Observational2014-01-31Active, not recruiting
A Triple-Blind, Parallel Study to Investigate the Effect of Losartan Versus Atenolol on the Reduction of Morbidity and Mortality in Hypertensive Patients With Left Ventricular Hypertrophy[NCT00338260]Phase 3496 participants (Actual)Interventional1995-06-30Completed
Stroke Prediction Study Using a Model Based on Internet Search Queries[NCT04755959]450 participants (Anticipated)Observational2021-02-28Not yet recruiting
INternational VErapamil SR Trandolapril STudy[NCT00133692]Phase 422,000 participants Interventional1997-09-30Completed
A Randomised, Double-blind, Placebo Controlled, Parallel Group, Multi-centre Trial in Adult Subjects With Newly Diagnosed Type 1 Diabetes Mellitus Investigating the Effect of Verapamil SR on Preservation of Beta-cell Function (Ver-A-T1D)[NCT04545151]Phase 2138 participants (Anticipated)Interventional2021-02-08Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for hydrochlorothiazide and Stroke

ArticleYear
Losartan/Hydrochlorothiazide: a review of its use in the treatment of hypertension and for stroke risk reduction in patients with hypertension and left ventricular hypertrophy.
    Drugs, 2009, Jun-18, Volume: 69, Issue:9

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Diuretics; Drug Combinati

2009
A polypill for all? Critical review of the polypill literature for primary prevention of cardiovascular disease and stroke.
    The Annals of pharmacotherapy, 2012, Volume: 46, Issue:5

    Topics: Antihypertensive Agents; Aspirin; Atenolol; Cardiovascular Diseases; Drug Combinations; Humans; Hydr

2012
Protection against stroke and dementia: an update on the latest clinical trial evidence.
    Current hypertension reports, 2004, Volume: 6, Issue:4

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl

2004
Fixed combination of losartan and hydrochlorothiazide and reduction of risk of stroke.
    Vascular health and risk management, 2007, Volume: 3, Issue:3

    Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Drug Therapy, Combination; Humans;

2007

Trials

11 trials available for hydrochlorothiazide and Stroke

ArticleYear
Amlodipine+benazepril is superior to hydrochlorothiazide+benazepril irrespective of baseline pulse pressure: subanalysis of the ACCOMPLISH trial.
    Journal of clinical hypertension (Greenwich, Conn.), 2015, Volume: 17, Issue:2

    Topics: Aged; Amlodipine; Antihypertensive Agents; Benzazepines; Blood Pressure; Double-Blind Method; Drug T

2015
Effects of hydrochlorothiazide on oxidative stress and pulse pressure in hypertensive patients with chronic stroke: the EMINENT study.
    Internal medicine (Tokyo, Japan), 2015, Volume: 54, Issue:6

    Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive A

2015
Cardiovascular outcomes in hypertensive patients: comparing single-agent therapy with combination therapy.
    Journal of hypertension, 2012, Volume: 30, Issue:11

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Double-Blind Met

2012
Effects of losartan on cardiovascular morbidity and mortality in patients with isolated systolic hypertension and left ventricular hypertrophy: a Losartan Intervention for Endpoint Reduction (LIFE) substudy.
    JAMA, 2002, Sep-25, Volume: 288, Issue:12

    Topics: Aged; Antihypertensive Agents; Atenolol; Cardiovascular Diseases; Double-Blind Method; Female; Human

2002
Effects of losartan on cardiovascular morbidity and mortality in patients with isolated systolic hypertension and left ventricular hypertrophy: a Losartan Intervention for Endpoint Reduction (LIFE) substudy.
    JAMA, 2002, Sep-25, Volume: 288, Issue:12

    Topics: Aged; Antihypertensive Agents; Atenolol; Cardiovascular Diseases; Double-Blind Method; Female; Human

2002
Effects of losartan on cardiovascular morbidity and mortality in patients with isolated systolic hypertension and left ventricular hypertrophy: a Losartan Intervention for Endpoint Reduction (LIFE) substudy.
    JAMA, 2002, Sep-25, Volume: 288, Issue:12

    Topics: Aged; Antihypertensive Agents; Atenolol; Cardiovascular Diseases; Double-Blind Method; Female; Human

2002
Effects of losartan on cardiovascular morbidity and mortality in patients with isolated systolic hypertension and left ventricular hypertrophy: a Losartan Intervention for Endpoint Reduction (LIFE) substudy.
    JAMA, 2002, Sep-25, Volume: 288, Issue:12

    Topics: Aged; Antihypertensive Agents; Atenolol; Cardiovascular Diseases; Double-Blind Method; Female; Human

2002
Effects of immediate versus delayed antihypertensive therapy on outcome in the Systolic Hypertension in Europe Trial.
    Journal of hypertension, 2004, Volume: 22, Issue:4

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus; Dihydrop

2004
Stroke prevention with the angiotensin II type 1-receptor blocker candesartan in elderly patients with isolated systolic hypertension: the Study on Cognition and Prognosis in the Elderly (SCOPE).
    Journal of the American College of Cardiology, 2004, Sep-15, Volume: 44, Issue:6

    Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimida

2004
The Felodipine Event Reduction (FEVER) Study: a randomized long-term placebo-controlled trial in Chinese hypertensive patients.
    Journal of hypertension, 2005, Volume: 23, Issue:12

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Ch

2005
Predictors of development of diabetes mellitus in patients with coronary artery disease taking antihypertensive medications (findings from the INternational VErapamil SR-Trandolapril STudy [INVEST]).
    The American journal of cardiology, 2006, Oct-01, Volume: 98, Issue:7

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Body Mass Index; Calcium Chann

2006
Predictors of development of diabetes mellitus in patients with coronary artery disease taking antihypertensive medications (findings from the INternational VErapamil SR-Trandolapril STudy [INVEST]).
    The American journal of cardiology, 2006, Oct-01, Volume: 98, Issue:7

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Body Mass Index; Calcium Chann

2006
Predictors of development of diabetes mellitus in patients with coronary artery disease taking antihypertensive medications (findings from the INternational VErapamil SR-Trandolapril STudy [INVEST]).
    The American journal of cardiology, 2006, Oct-01, Volume: 98, Issue:7

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Body Mass Index; Calcium Chann

2006
Predictors of development of diabetes mellitus in patients with coronary artery disease taking antihypertensive medications (findings from the INternational VErapamil SR-Trandolapril STudy [INVEST]).
    The American journal of cardiology, 2006, Oct-01, Volume: 98, Issue:7

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Body Mass Index; Calcium Chann

2006
Impact of losartan on stroke risk in hypertensive patients in primary care.
    Clinical drug investigation, 2007, Volume: 27, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Dr

2007
Baseline characteristics in the Avoiding Cardiovascular events through Combination therapy in Patients Living with Systolic Hypertension (ACCOMPLISH) trial: a hypertensive population at high cardiovascular risk.
    Blood pressure, 2007, Volume: 16, Issue:1

    Topics: Aged; Amlodipine; Antihypertensive Agents; Benzazepines; Body Mass Index; Diabetes Mellitus, Type 2;

2007
[The FEVER (Felodipine EVEnt Reduction) trial; a randomised, double-blind, placebo-controlled trial in Chinese hypertensive patients].
    Vnitrni lekarstvi, 2007, Volume: 53, Issue:1

    Topics: Aged; Calcium Channel Blockers; China; Diuretics; Double-Blind Method; Felodipine; Female; Humans; H

2007

Other Studies

14 other studies available for hydrochlorothiazide and Stroke

ArticleYear
Cost-benefit analysis of the polypill in the primary prevention of myocardial infarction and stroke.
    European journal of epidemiology, 2016, Volume: 31, Issue:4

    Topics: Aged; Aged, 80 and over; Amlodipine; Aspirin; Cardiovascular Agents; Case-Control Studies; Cohort St

2016
Starting the polypill: the use of a single age cut-off in males and females.
    Journal of medical screening, 2017, Volume: 24, Issue:1

    Topics: Adult; Age Factors; Aged; Cardiovascular Agents; Drug Combinations; Female; Humans; Hydrochlorothiaz

2017
Olmesartan reduces oxidative stress in the brain of stroke-prone spontaneously hypertensive rats assessed by an in vivo ESR method.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2009, Volume: 32, Issue:12

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Brain; El

2009
[Treatment of patients with arterial hypertension and other stroke risk factors in clinical practice. The PROGNOS program].
    Terapevticheskii arkhiv, 2009, Volume: 81, Issue:9

    Topics: Aged; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle A

2009
Candesartan and amlodipine combination therapy provides powerful vascular protection in stroke-prone spontaneously hypertensive rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:2

    Topics: Acetylcholine; Amlodipine; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blo

2011
Chlorthalidone reduces cardiovascular events compared with hydrochlorothiazide: a retrospective cohort analysis.
    Hypertension (Dallas, Tex. : 1979), 2011, Volume: 57, Issue:4

    Topics: Adult; Angina Pectoris; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Cholesterol; Heart

2011
[Antihypertensive therapy in routine practice: fixed or free combination? Fixed combination scores with better prognosis].
    MMW Fortschritte der Medizin, 2011, Sep-01, Volume: 153, Issue:35

    Topics: Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Drug Combinations; Huma

2011
[Fixed combination of AT1 blocker and diuretic. Stroke preventive combination for hypertension].
    MMW Fortschritte der Medizin, 2002, Jul-11, Volume: 144, Issue:27-28

    Topics: Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Stroke; Tetrazoles; Treatment Outcome;

2002
[LIFE study proves preventive action. With losartan to do even more against stroke].
    MMW Fortschritte der Medizin, 2003, Volume: 145 Suppl 1

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Antihypertensive Agents; Atenolol; Diabetes Co

2003
Introduction to monitoring. What is what you prescribed actually doing?
    Australian family physician, 2003, Volume: 32, Issue:10

    Topics: Acetaminophen; Aged; Aspirin; Australia; Celecoxib; Drug Interactions; Drug Therapy, Combination; Fa

2003
Comparison of the effects of omapatrilat and irbesartan/hydrochlorothiazide on endothelial function and cardiac hypertrophy in the stroke-prone spontaneously hypertensive rat: sex differences.
    Journal of hypertension, 2004, Volume: 22, Issue:2

    Topics: Animals; Antihypertensive Agents; Biological Availability; Biphenyl Compounds; Blood Pressure; Carba

2004
[AT-1 blockers are different in their effects. The forgetful patients begin to notice it especially].
    MMW Fortschritte der Medizin, 2003, Apr-10, Volume: 145, Issue:15

    Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds

2003
[Plus point -- risk reduction].
    MMW Fortschritte der Medizin, 2006, Aug-17, Volume: 148, Issue:33-34

    Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents

2006
Predicting stroke risk in hypertensive patients with coronary artery disease: a report from the INVEST.
    Stroke, 2008, Volume: 39, Issue:2

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Atenolol; Black People; Coronary Artery Disease; D

2008