hydrochlorothiazide and Recrudescence

hydrochlorothiazide has been researched along with Recrudescence in 47 studies

Research

Studies (47)

Timeframe	Studies, this research(%)	All Research%
pre-1990	23 (48.94)	18.7374
1990's	6 (12.77)	18.2507
2000's	5 (10.64)	29.6817
2010's	7 (14.89)	24.3611
2020's	6 (12.77)	2.80

Authors

Authors	Studies
Bedino, G; Bonny, O; Bucher, C; Buchkremer, F; Cereghetti, GM; Christe, A; Del Giorno, R; Dhayat, NA; Ernandez, T; Faller, N; Fuster, DG; Gabutti, L; Grosse, P; Hüsler, C; Koneth, I; Mayr, M; Mohebbi, N; Odermatt, U; Pellegrini, L; Ritter, A; Roth, B; Roumet, M; Stoermann-Chopard, C; Tamò, L; Teta, D; Trelle, S; Venzin, RM; Vogt, B	1
Veser, J	1
Chen, DC; Eapen, R; Lawrentschuk, N; McVey, A; Murphy, DG	1
Akıncı, K; Albayati, A; Özkan, B; Savran, S; Uysal, AÇ; Uysal, Pİ	1
Bellmann, B; Filipovic, K; LÜker, J; Plenge, T; Steven, D; Sultan, A	1
Bonny, O; Bosshard, P; Roth, B; Stritt, K	1
Jansson, PS; Lee, J; Leisten, DC; Sarkisian, TM; Wilcox, SR	1
Amico, P; Bedino, G; Bonny, O; Buchkremer, F; Del Giorno, R; Dhayat, NA; Ernandez, T; Faller, N; Fuster, DG; Gabutti, L; Hüsler, C; Irincheeva, I; Koneth, I; Mayr, M; Mohebbi, N; Odermatt, U; Pellegrini, L; Rintelen, F; Ritter, A; Roth, B; Roumet, M; Schönholzer, C; Stoermann-Chopard, C; Tamò, L; Teta, D; Trelle, S; Venzin, RM; Vogt, B	1
Ehrlich, Y; Goldberg, H; Golomb, D; Lifshitz, D; Margel, D; Nevo, A	1
Astor, BC; Gundu, V; Jhagroo, RA; Wolfgram, DF	1
Abad-Menor, F; Arrabal-Martín, M; Arrabal-Polo, MÁ; Cano-García, MD; Cózar-Olmo, JM; De Haro-Muñoz, T; González-Torres, S	1
Bechler, R; Berg, W; Haas, C; Laube, N	1
Plosker, GL	1
Chamorro Borraz, N; Maroto Rodríguez, B; Meyer García-Sípido, E; Rebollo Ferreiro, J; Sanz Sanz, CL	1
Arias-Santiago, S; Arrabal-Martin, M; Arrabal-Polo, MA; de Haro-Muñoz, T; Gonzalez-Torres, S; Lopez-Ruiz, A; Orgaz-Molina, J; Zuluaga-Gomez, A	1
Clavel, J; Lacour, B; Sayegh, F; Ulmann, A	1
Laerum, E; Larsen, S	2
Braun, J; Duhme, C; May, P; Pilorz, H; Pöpperl, H	1
Laerum, E	1
Sterkowicz, W	1
Ulmann, A	1
Johnson, JE; Wright, LF	1
Jerkins, G; Noe, HN; Roy, S; Stapleton, FB	1
Bick, C; Brien, G; Fahlenkamp, D; Koch, R	1
Brouhard, BH; Kalia, A; Travis, LB	1
Döring, B; Minne, H; Russmann, D; Uhl, K; Ziegler, R	1
Ishikawa, A; Kageyama, S; Kawabe, K; Kurita, Y; Ohta, N; Suzuki, K; Ushiyama, T	1
Buys, ME; Margolius, LP; Martins, MC; Meyers, AM; Whalley, NA	1
Dormans, TP; Gerlag, PG	1
Cervantes, M; Jordana, R; Mas, A; Vallés, J	1
Moner Coromina, L; Peñarrubia María, MT; Torné Cachot, J	1
Domingos, F; Fortes, A; Prata, MM; Simöes, A	1
d'Aloia, A; Dei Cas, L; Faggiano, P; Fiorina, C; Vizzardi, E	1
Thomas, WC	1
Ehrig, U; Siddiqui, AA; Wilson, DR	1
Cohanim, M; Yendt, ER	1
Głuszek, J; Musialik, D; Raszeja-Wanic, B	1
Pereyo, N	1
Sandvall, K; Tiselius, HG	1
Ala-Opas, M; Alfthan, O; Elomaa, I; Porkka, L	1
Casas, E; García Puig, J; González Sanz, A; Mateos, F; Michan, A	1
Jordan, DR; Valberg, JD	1
Benazzi, E; Colussi, G; De Ferrari, ME; Malberti, F; Minetti, L; Rombolà, G; Surian, M	1
D'Angelo, A; Fabris, A; Ferrari, S; Giannini, S; Malvasi, L; Maschio, G; Morbiato, F; Rugiu, C; Sartori, L; Tessitore, N	1
Cahen, R; François, B; Semet, MP; Trolliet, P	1
Gershon, S; Shopsin, B	1

Reviews

1 review(s) available for hydrochlorothiazide and Recrudescence

Article	Year
Eprosartan: a review of its use in hypertension. Drugs, 2009, Volume: 69, Issue:17 Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Body Mass Index; Cardiovascular Diseases; Clinical Trials as Topic; Cough; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Incidence; Nitrendipine; Randomized Controlled Trials as Topic; Receptors, Angiotensin; Recurrence; Risk Factors; Sodium Chloride Symporter Inhibitors; Thiophenes; Treatment Outcome	2009

Article

Year

Eprosartan: a review of its use in hypertension.

Drugs, 2009, Volume: 69, Issue:17

Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Body Mass Index; Cardiovascular Diseases; Clinical Trials as Topic; Cough; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Incidence; Nitrendipine; Randomized Controlled Trials as Topic; Receptors, Angiotensin; Recurrence; Risk Factors; Sodium Chloride Symporter Inhibitors; Thiophenes; Treatment Outcome

2009

Trials

10 trial(s) available for hydrochlorothiazide and Recrudescence

Article	Year
Hydrochlorothiazide and Prevention of Kidney-Stone Recurrence. The New England journal of medicine, 2023, 03-02, Volume: 388, Issue:9 Topics: Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hydrochlorothiazide; Kidney; Kidney Calculi; Recurrence; Sodium Chloride Symporter Inhibitors	2023
Efficacy of standard and low dose hydrochlorothiazide in the recurrence prevention of calcium nephrolithiasis (NOSTONE trial): protocol for a randomized double-blind placebo-controlled trial. BMC nephrology, 2018, 12-10, Volume: 19, Issue:1 Topics: Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Male; Nephrolithiasis; Prospective Studies; Recurrence; Treatment Outcome	2018
[Incidence of lithiasic recurrence after a diuretic therapy, alone or combined with treatment by a thiazide diuretic or phosphorus]. Presse medicale (Paris, France : 1983), 1984, May-12, Volume: 13, Issue:20 Topics: Adult; Beverages; Calcium; Combined Modality Therapy; Creatinine; Diuresis; Female; Humans; Hydrochlorothiazide; Kidney Calculi; Male; Phosphorus; Prospective Studies; Recurrence	1984
Thiazide prophylaxis of urolithiasis. A double-blind study in general practice. Acta medica Scandinavica, 1984, Volume: 215, Issue:4 Topics: Adolescent; Adult; Aged; Calcium; Clinical Trials as Topic; Double-Blind Method; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Male; Middle Aged; Prospective Studies; Random Allocation; Recurrence; Uric Acid; Urinary Calculi	1984
Metabolic effects of thiazide versus placebo in patients under long-term treatment for recurrent urolithiasis. Scandinavian journal of urology and nephrology, 1984, Volume: 18, Issue:2 Topics: Adolescent; Adult; Aged; Calcium; Female; Humans; Hydrochlorothiazide; Magnesium; Male; Middle Aged; Placebos; Recurrence; Uric Acid; Urinary Calculi	1984
Indapamide (Natrilix): the agent of choice in the treatment of recurrent renal calculi associated with idiopathic hypercalciuria. British journal of urology, 1996, Volume: 78, Issue:2 Topics: Calcium; Cross-Over Studies; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hydrochlorothiazide; Indapamide; Kidney Calculi; Recurrence	1996
Combination of high-dose furosemide and hydrochlorothiazide in the treatment of refractory congestive heart failure. European heart journal, 1996, Volume: 17, Issue:12 Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Diuretics; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Furosemide; Heart Failure; Humans; Hydrochlorothiazide; Male; Middle Aged; Recurrence; Sodium Chloride Symporter Inhibitors; Treatment Outcome	1996
Unprocessed bran and intermittent thiazide therapy in prevention of recurrent urinary calcium stones. Scandinavian journal of urology and nephrology, 1987, Volume: 21, Issue:4 Topics: Adult; Aged; Calcium; Dietary Fiber; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Periodicity; Recurrence; Seasons; Urinary Calculi	1987
Is it possible to characterize recurrent urinary stone formers who benefit from thiazide prophylaxis? Application of discrimination analysis. Acta medica Scandinavica, 1987, Volume: 221, Issue:1 Topics: Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Recurrence; Statistics as Topic; Urinary Calculi	1987
The current status of lithium in psychiatry. The American journal of the medical sciences, 1974, Volume: 268, Issue:6 Topics: Acute Disease; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Depression; Female; Haloperidol; Humans; Hydrochlorothiazide; In Vitro Techniques; Lithium; Male; Mental Disorders; Placebos; Premenstrual Syndrome; Psychopharmacology; Recurrence; Thyroid Function Tests; Thyroid Gland; United States	1974

Other Studies

36 other study(ies) available for hydrochlorothiazide and Recrudescence

Article	Year
Re: Hydrochlorothiazide and Prevention of Kidney-stone Recurrence. European urology, 2023, Volume: 84, Issue:2 Topics: Humans; Hydrochlorothiazide; Kidney; Kidney Calculi; Recurrence	2023
Re: Hydrochlorothiazide and Prevention of Kidney-Stone Recurrence (NOSTONE). European urology, 2023, Volume: 84, Issue:3 Topics: Humans; Hydrochlorothiazide; Kidney; Kidney Calculi; Recurrence	2023
The effect of hydrochlorothiazide on the recurrence of nonmelanoma skin cancer: a 7-year retrospective study comprising 300 patients. Turkish journal of medical sciences, 2023, Volume: 53, Issue:3 Topics: Aged; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Humans; Hydrochlorothiazide; Recurrence; Retrospective Studies; Skin Neoplasms	2023
Hydrochlorothiazide therapy: impact on early recurrence of atrial fibrillation after catheter ablation? Minerva cardiology and angiology, 2021, Volume: 69, Issue:1 Topics: Atrial Fibrillation; Catheter Ablation; Humans; Hydrochlorothiazide; Recurrence; Retrospective Studies	2021
[Prevention of nephrolithiasis - Preliminary results of the Swiss Kidney Stone Cohort (SKSC) and the NOSTONE trial]. Revue medicale suisse, 2020, Dec-02, Volume: 16, Issue:717 Topics: Clinical Trials as Topic; Cohort Studies; Humans; Hydrochlorothiazide; Kidney Calculi; Recurrence; Secondary Prevention; Switzerland	2020
Recurrent Hydrochlorothiazide-Induced Acute Respiratory Distress Syndrome Treated With Extracorporeal Membrane Oxygenation. The Journal of emergency medicine, 2018, Volume: 55, Issue:6 Topics: Antihypertensive Agents; Extracorporeal Membrane Oxygenation; Humans; Hydrochlorothiazide; Male; Middle Aged; Recurrence; Respiratory Distress Syndrome	2018
Long-Term Adherence to Medications in Secondary Prevention of Urinary Tract Stones. Journal of endourology, 2019, Volume: 33, Issue:6 Topics: Adult; Aged; Citric Acid; Female; Humans; Hydrochlorothiazide; Israel; Kidney Calculi; Male; Medication Adherence; Middle Aged; Recurrence; Secondary Prevention; Young Adult	2019
Hydrochlorothiazide compared to chlorthalidone in reduction of urinary calcium in patients with kidney stones. Urolithiasis, 2013, Volume: 41, Issue:4 Topics: Calcium; Chlorthalidone; Diuretics; Female; Humans; Hydrochlorothiazide; Kidney Calculi; Male; Middle Aged; Recurrence; Retrospective Studies	2013
Urine Calcium and Bone Mineral Density in Calcium Stone-Forming Patients Treated with Alendronate and Hydrochlorothiazide. Urologia internationalis, 2016, Volume: 97, Issue:3 Topics: Alendronate; Bone Density; Bone Density Conservation Agents; Calcium; Diuretics; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Kidney Calculi; Male; Middle Aged; Prospective Studies; Recurrence; Time Factors	2016
Relevance of the BONN Risk Index for metabolic monitoring of patients with calcium oxalate urolithiasis: a clinical application study of the Urolizer. Urological research, 2009, Volume: 37, Issue:2 Topics: Adult; Aged; Calcium Oxalate; Citric Acid; Crystallization; Female; Humans; Hydrochlorothiazide; Hydrogen-Ion Concentration; Hypercalciuria; Linear Models; Male; Middle Aged; Models, Biological; Recurrence; Risk Factors; Urolithiasis	2009
[Recurrent non-cardiogenic lung edema secondary to the oral administration of hydrochlorothiazide]. Medicina intensiva, 2011, Volume: 35, Issue:8 Topics: Administration, Oral; Aged, 80 and over; Antihypertensive Agents; Female; Humans; Hydrochlorothiazide; Pulmonary Edema; Recurrence	2011
Effects of aminobisphosphonates and thiazides in patients with osteopenia/osteoporosis, hypercalciuria, and recurring renal calcium lithiasis. Urology, 2013, Volume: 81, Issue:4 Topics: Alendronate; Bone Density; Bone Density Conservation Agents; Bone Diseases, Metabolic; Calcium; Female; Humans; Hydrochlorothiazide; Hypercalciuria; Kidney Calculi; Male; Middle Aged; Nephrolithiasis; Osteoporosis; Prospective Studies; Recurrence; Sodium Chloride Symporter Inhibitors	2013
[Prevention of urinary calculi with thiazides and allopurinol. A long-term study]. Der Urologe. Ausg. A, 1984, Volume: 23, Issue:2 Topics: Adult; Allopurinol; Calcium Oxalate; Calcium Phosphates; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Long-Term Care; Male; Recurrence; Urinary Calculi	1984
[Case of recurrent ventricular fibrillation caused by iatrogenic hypokalemia]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1984, Feb-01, Volume: 37, Issue:3 Topics: Female; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; Iatrogenic Disease; Middle Aged; Recurrence; Ventricular Fibrillation	1984
[Predictive value of lithogenic risk in hypercalciuria: should 24-hour urine calcium be measured?]. Nephrologie, 1984, Volume: 5, Issue:5 Topics: Calcium; Creatine; Follow-Up Studies; Humans; Hydrochlorothiazide; Hyperparathyroidism; Kidney Calculi; Phosphorus; Prospective Studies; Recurrence; Retrospective Studies; Risk; Time Factors	1984
Thiazide-induced hyponatremia. Southern medical journal, 1983, Volume: 76, Issue:11 Topics: Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Hyponatremia; Middle Aged; Neurologic Manifestations; Osmolar Concentration; Recurrence; Seizures; Sodium; Triamterene; Vasopressins	1983
Hypercalciuria in children with urolithiasis. American journal of diseases of children (1960), 1982, Volume: 136, Issue:8 Topics: Absorption; Adolescent; Calcium; Child; Child, Preschool; Creatinine; Female; Humans; Hydrochlorothiazide; Infant; Kidney; Male; Recurrence; Urinary Calculi	1982
[Hydrochlorothiazide in the metaphylaxis of recurrent calcium oxalate lithiasis]. Zeitschrift fur Urologie und Nephrologie, 1982, Volume: 75, Issue:11 Topics: Adult; Calcium Oxalate; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Potassium; Recurrence; Urinary Calculi	1982
The association of idiopathic hypercalciuria and asymptomatic gross hematuria in children. The Journal of pediatrics, 1981, Volume: 99, Issue:5 Topics: Calcium; Child; Child, Preschool; Female; Hematuria; Humans; Hydrochlorothiazide; Infant; Infant, Newborn; Male; Recurrence; Urinary Calculi	1981
[On the question of endocrine side effects in patients on medication for renal calcium stone disease (author's transl)]. Der Urologe. Ausg. A, 1980, Volume: 19, Issue:4 Topics: Calcium; Cellulose; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hyperparathyroidism, Secondary; Kidney Calculi; Male; Recurrence	1980
[Thiazide treatment for calcium urolithiasis in patients with idiopathic hypercalciuria]. Hinyokika kiyo. Acta urologica Japonica, 1994, Volume: 40, Issue:6 Topics: Adult; Aged; Calcium; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Recurrence; Urinary Calculi	1994
Recurrent hydrochlorothiazide-induced pulmonary edema. Intensive care medicine, 1998, Volume: 24, Issue:4 Topics: Aged; Antihypertensive Agents; Drug Hypersensitivity; Female; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Pulmonary Edema; Recurrence; Respiration, Artificial	1998
[Non-cardiogenic acute pulmonary edema and recurrent leukopenia caused by hydrochlorothiazide]. Revista clinica espanola, 2001, Volume: 201, Issue:2 Topics: Acute Disease; Antihypertensive Agents; Diuretics; Female; Humans; Hydrochlorothiazide; Leukopenia; Middle Aged; Pulmonary Edema; Recurrence; Sodium Chloride Symporter Inhibitors	2001
Type 1 glycogen storage disease and recurrent calcium nephrolithiasis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2001, Volume: 16, Issue:6 Topics: Absorptiometry, Photon; Adolescent; Allopurinol; Amiloride; Calcinosis; Diet, Sodium-Restricted; Diuretics; Drug Therapy, Combination; Glycogen Storage Disease Type I; Gout Suppressants; Humans; Hydrochlorothiazide; Kidney Calculi; Male; Osteoporosis; Recurrence	2001
[Recurrent episodes of acute non-cardiogenic pulmonary edema caused by ingesting hydrochlorothiazide]. Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology, 2001, Volume: 2, Issue:8 Topics: Diuretics; Female; Humans; Hydrochlorothiazide; Middle Aged; Pulmonary Edema; Recurrence; Sodium Chloride Symporter Inhibitors	2001
Clinical concepts of renal calculous disease. The Journal of urology, 1975, Volume: 113, Issue:4 Topics: Adult; Age Factors; Blood Chemical Analysis; Calcium; Child; Citrates; Cystinuria; Diet Therapy; Female; Humans; Hydrochlorothiazide; Hydrogen-Ion Concentration; Kidney Calculi; Malabsorption Syndromes; Male; Medical History Taking; Oxalates; Phosphorus; Racial Groups; Recurrence; Sex Factors; Uric Acid; Urinary Tract Infections; Urine; Urography	1975
The effect of thiazide diuretics on carbohydrate-induced calciuria in patients with recurrent renal calculi. The Journal of laboratory and clinical medicine, 1975, Volume: 86, Issue:1 Topics: Adult; Ammonia; Calcium; Creatinine; Dietary Carbohydrates; Diuretics; Female; Glucose; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hydrogen-Ion Concentration; Kidney Calculi; Magnesium; Male; Middle Aged; Phosphorus; Potassium; Recurrence; Sodium; Sodium Chloride Symporter Inhibitors	1975
Thiazides and calcium urolithiasis. Canadian Medical Association journal, 1978, Apr-08, Volume: 118, Issue:7 Topics: Calcium; Diuretics; Humans; Hydrochlorothiazide; Kidney Calculi; Recurrence; Sodium Chloride Symporter Inhibitors	1978
[Effect of hydrochlorothiazide on calcium-magnesium parameters in patients with recurrent nephrolithiasis]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1978, Jul-24, Volume: 33, Issue:30 Topics: Adult; Calcium; Female; Humans; Hydrochlorothiazide; Kidney Calculi; Magnesium; Male; Middle Aged; Recurrence	1978
Possible cross-reactivity between hydrochlorothiazide and sulfanilic acid. International journal of dermatology, 1991, Volume: 30, Issue:8 Topics: Cross Reactions; Humans; Hydrochlorothiazide; Lupus Erythematosus, Cutaneous; Photosensitivity Disorders; Recurrence; Sulfanilic Acids	1991
How are urine composition and stone disease affected by therapeutic measures at an outpatient stone clinic? European urology, 1990, Volume: 17, Issue:3 Topics: Allopurinol; Bendroflumethiazide; Calcium Oxalate; Citrates; Citric Acid; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Magnesium Oxide; Male; Outpatient Clinics, Hospital; Phosphates; Recurrence; Urinary Calculi	1990
[Hypercalciuria as a possible cause of recurrent hematuria in childhood]. Anales espanoles de pediatria, 1988, Volume: 28, Issue:4 Topics: Calcium; Child; Hematuria; Humans; Hydrochlorothiazide; Male; Recurrence; Uric Acid	1988
Dyschromatopsia following cataract surgery. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1986, Volume: 21, Issue:4 Topics: Aged; Aphakia, Postcataract; Cataract Extraction; Color Vision Defects; Diuretics; Humans; Hydrochlorothiazide; Lenses, Intraocular; Male; Middle Aged; Migraine Disorders; Postoperative Complications; Recurrence; Snow; Sunlight; Time Factors	1986
Medical treatment of idiopathic calcium nephrolithiasis. Contributions to nephrology, 1987, Volume: 58 Topics: Allopurinol; Amiloride; Calcium; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hyperoxaluria; Kidney Calculi; Recurrence; Retrospective Studies; Uric Acid	1987
Long-term effects of low-dose thiazide and amiloride administration in recurrent renal stone formers. Contributions to nephrology, 1985, Volume: 49 Topics: Adult; Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hyperparathyroidism; Kidney Calculi; Male; Middle Aged; Prognosis; Recurrence	1985
[Preventive medical treatment of recurrent urinary calcium calculi]. Nephrologie, 1986, Volume: 7, Issue:1 Topics: Adult; Allopurinol; Amiloride; Calcium; Diuresis; Drug Therapy, Combination; Female; Fluid Therapy; Humans; Hydrochlorothiazide; Kidney Calculi; Male; Middle Aged; Recurrence; Retrospective Studies; Succinimides	1986