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hydrochlorothiazide and Potassium Deficiency

hydrochlorothiazide has been researched along with Potassium Deficiency in 15 studies

Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.

Potassium Deficiency: A condition due to decreased dietary intake of potassium, as in starvation or failure to administer in intravenous solutions, or to gastrointestinal loss in diarrhea, chronic laxative abuse, vomiting, gastric suction, or bowel diversion. Severe potassium deficiency may produce muscular weakness and lead to paralysis and respiratory failure. Muscular malfunction may result in hypoventilation, paralytic ileus, hypotension, muscle twitches, tetany, and rhabomyolysis. Nephropathy from potassium deficit impairs the concentrating mechanism, producing POLYURIA and decreased maximal urinary concentrating ability with secondary POLYDIPSIA. (Merck Manual, 16th ed)

Research Excerpts

ExcerptRelevanceReference
"Supplementation of potassium alone and in combination with magnesium was compared in 10 patients with chronic compensated heart failure receiving hydrochlorothiazide 50 mg twice daily for the whole trial."9.06Comparison of potassium alone and potassium-magnesium supplementation in patients with heart failure using hydrochlorothiazide. ( Gordin, A; Kohvakka, A; Luurila, O; Sundberg, S, 1989)
"In a group of elderly patients with systolic hypertension the hypotensive efficacy and adverse effects were studied of hydrochlorothiazide given in daily doses of 25 mg in a year."7.67[Hypotensive and metabolic effects of small doses of hydrochlorothiazide in the long-term treatment of elderly patients with systolic arterial hypertension]. ( Halawa, B, 1989)
"Supplementation of potassium alone and in combination with magnesium was compared in 10 patients with chronic compensated heart failure receiving hydrochlorothiazide 50 mg twice daily for the whole trial."5.06Comparison of potassium alone and potassium-magnesium supplementation in patients with heart failure using hydrochlorothiazide. ( Gordin, A; Kohvakka, A; Luurila, O; Sundberg, S, 1989)
"The effect of potassium ion (K+) depletion on postmyocardial infarction ventricular arrhythmias was investigated in 32 dogs: 12 control animals, 10 animals that ate a diet extremely low in K+ for 15 days, and 10 others that, in addition to dietary K+ deprivation, received 50 mg of hydrochlorothiazide four times."3.67The effect of potassium ion depletion on postinfarction canine cardiac arrhythmias. ( Bodvarsson, M; Canzanello, VJ; Garan, H; Harrington, JT; Madias, NE; McCauley, J; McGovern, BA; Newell, JB; Ruskin, JN, 1988)
"In a group of elderly patients with systolic hypertension the hypotensive efficacy and adverse effects were studied of hydrochlorothiazide given in daily doses of 25 mg in a year."3.67[Hypotensive and metabolic effects of small doses of hydrochlorothiazide in the long-term treatment of elderly patients with systolic arterial hypertension]. ( Halawa, B, 1989)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199013 (86.67)18.7374
1990's2 (13.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
RICHTERICH, R1
KENNEDY, GC1
PARKER, RA1
EARLEY, LE1
ORLOFF, J1
WALKER, WJ1
ELKINS, JT1
WOOD, LW1
Stefíková, K1
Spustová, V1
Dzúrik, R1
Glezer, GA1
Merzon, AK1
Lipko, DS1
Donskova, TV1
Levinzon, AM1
Shelest, IuP1
Garan, H1
McGovern, BA1
Canzanello, VJ1
McCauley, J1
Bodvarsson, M1
Harrington, JT1
Madias, NE1
Newell, JB1
Ruskin, JN1
Halawa, B1
Kohvakka, A1
Luurila, O1
Gordin, A1
Sundberg, S1
Hohenegger, M1
Tarpley, EL1
Sitt, R1
Senft, G1
Losert, W1
Kaess, H2
Schliert, G1
Ehlers, W1
von Mikulicz-Radecki, JG1
Hassenstein, P1
Walter, K1
Brech, W1
Hengstmann, J1
Vinogradov, AV1
Matveev, LN1
Remenchik, AP1
Miller, C1
Talso, PJ1
Willoughby, EO1

Reviews

1 review available for hydrochlorothiazide and Potassium Deficiency

ArticleYear
THIAZIDE DIURETICS.
    Annual review of medicine, 1964, Volume: 15

    Topics: Antihypertensive Agents; Benzothiadiazines; Chlorothiazide; Chlorthalidone; Diabetes Insipidus; Diur

1964

Trials

2 trials available for hydrochlorothiazide and Potassium Deficiency

ArticleYear
Comparison of potassium alone and potassium-magnesium supplementation in patients with heart failure using hydrochlorothiazide.
    Magnesium, 1989, Volume: 8, Issue:2

    Topics: Aged; Blood Pressure; Body Weight; Double-Blind Method; Female; Heart Failure; Heart Rate; Humans; H

1989
Controlled-release potassium supplementation.
    Current therapeutic research, clinical and experimental, 1974, Volume: 16, Issue:7

    Topics: Adult; Blood Pressure; Chlorides; Chlorothiazide; Chlorthalidone; Clinical Trials as Topic; Delayed-

1974

Other Studies

12 other studies available for hydrochlorothiazide and Potassium Deficiency

ArticleYear
Potassium loss during treatment with chlorothiazide and hydrochlorothiazide.
    Lancet (London, England), 1959, May-30, Volume: 1, Issue:7083

    Topics: Acetazolamide; Chlorothiazide; Hydrochlorothiazide; Potassium; Potassium Deficiency

1959
The effect of hydrochlorothiazide on the kidney of the electrolyte-deficient rat.
    Quarterly journal of experimental physiology and cognate medical sciences, 1963, Volume: 48

    Topics: Animals; Desoxycorticosterone; Electrolytes; Hydrochlorothiazide; Hypokalemia; Kidney; Potassium Def

1963
EFFECT OF POTASSIUM IN RESTORING MYOCARDIAL RESPONSE TO A SUBTHRESHOLD CARDIAC PACEMAKER.
    The New England journal of medicine, 1964, Sep-17, Volume: 271

    Topics: Adams-Stokes Syndrome; Calcium; Electrocardiography; Geriatrics; Heart Block; Hydrochlorothiazide; H

1964
Acute effect of hydrochlorothiazide on renal calcium and magnesium handling in postmenopausal women.
    Physiological research, 1999, Volume: 48, Issue:4

    Topics: Absorption; Calcium; Diuretics; Female; Humans; Hydrochlorothiazide; Kidney; Kidney Tubules; Magnesi

1999
[Comparative study of potassium-sparing effects of triamterene and amiloride in the treatment with hydrochlorothiazide].
    Klinicheskaia meditsina, 1990, Volume: 68, Issue:9

    Topics: Amiloride; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Potassium Deficienc

1990
The effect of potassium ion depletion on postinfarction canine cardiac arrhythmias.
    Circulation, 1988, Volume: 77, Issue:3

    Topics: Animals; Dogs; Electrophysiology; Female; Hydrochlorothiazide; Ion Channels; Myocardial Infarction;

1988
[Hypotensive and metabolic effects of small doses of hydrochlorothiazide in the long-term treatment of elderly patients with systolic arterial hypertension].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1989, Feb-15, Volume: 42, Issue:4

    Topics: Age Factors; Aged; Humans; Hydrochlorothiazide; Hypertension; Magnesium Deficiency; Male; Potassium

1989
Letter: Fate of potassium supplements during diuretic therapy.
    Lancet (London, England), 1973, Nov-24, Volume: 2, Issue:7839

    Topics: Acetazolamide; Amiloride; Animals; Diuretics; Hydrochlorothiazide; Mannitol; Potassium; Potassium Ch

1973
[The effect of hydrochlorthiazide on the blood sugar-increasing action of diazoxide].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1966, Volume: 253, Issue:3

    Topics: Animals; Antihypertensive Agents; Carbohydrate Metabolism; Diazoxide; Hydrochlorothiazide; Hyperglyc

1966
The carbohydrate metabolism of normal subjects during potassium depletion.
    Diabetologia, 1971, Volume: 7, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Alkalosis; Bicarbonates; Carbohydrate Metabolism; Chlorides; Diet; F

1971
[Prevention of potassium metabolism disorders arising during the treatment of cardiac insufficiency with diuretics].
    Kardiologiia, 1967, Volume: 7, Issue:5

    Topics: Adult; Digitalis Glycosides; Diuretics; Drug Synergism; Female; Furosemide; Heart Failure; Humans; H

1967
Depletion of body potassium by diuretics.
    Circulation, 1966, Volume: 33, Issue:5

    Topics: Adult; Aged; Blood; Dichlorphenamide; Diuretics; Electrolytes; Humans; Hydrochlorothiazide; Middle A

1966