hydrochlorothiazide has been researched along with Nephrotic Syndrome in 29 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (96.55) | 18.7374 |
| 1990's | 1 (3.45) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ZOSIN, C | 1 |
| MANESCU, N | 1 |
| BROD, M | 1 |
| CIGADA, G | 1 |
| DE MINICIS, E | 1 |
| FALK, W | 1 |
| HINRICHS, R | 1 |
| KOESTENBERGER, R | 1 |
| KHOKHANI, RC | 1 |
| SHAH, PN | 1 |
| BOCK, HE | 1 |
| ANIBALDI, A | 3 |
| BOSCHERINI, B | 3 |
| PAIELLA, R | 1 |
| PATANE, E | 1 |
| PEDULLA, T | 1 |
| ROBSON, AO | 1 |
| KERR, DN | 1 |
| ASHCROFT, R | 1 |
| TEASDALE, G | 1 |
| SPERBER, RJ | 1 |
| DIRE, LB | 1 |
| SINGER, MM | 1 |
| FISCH, S | 1 |
| DEGRAFF, AC | 1 |
| SABBAGA, E | 1 |
| SALDANHA, RV | 1 |
| de FARIA, C | 1 |
| NUSSENZVEIG, I | 1 |
| RODARI, T | 1 |
| REGAZZINI, A | 1 |
| TRONCONI, L | 1 |
| Soyka, LF | 1 |
| Kaur, J | 1 |
| Wahi, PL | 1 |
| Knauf, H | 1 |
| Mutschler, E | 1 |
| Nakahama, H | 1 |
| Orita, Y | 1 |
| Yamazaki, M | 1 |
| Itoh, S | 1 |
| Okuda, T | 1 |
| Yamaji, A | 1 |
| Miwa, Y | 1 |
| Yanase, M | 1 |
| Fukuhara, Y | 1 |
| Kamada, T | 1 |
| Riechers, G | 1 |
| Futerova, M | 1 |
| Hanisch, M | 1 |
| Ritter, W | 1 |
| Kühn, K | 1 |
| Black, JA | 1 |
| Challacombe, DN | 1 |
| Ockenden, BG | 1 |
| Precht, K | 1 |
| Klinkmann, H | 1 |
| Nieth, H | 1 |
| Murphy, AV | 1 |
| Chaudhury, RR | 1 |
| Chugh, KS | 1 |
| Gupta, GS | 1 |
| Sodhi, P | 1 |
| Gupta, KK | 1 |
| Radó, JP | 2 |
| Marosi, J | 1 |
| Takó, J | 2 |
| Szende, L | 1 |
| Dévényi, I | 1 |
| Koshikawa, S | 1 |
| Sasaoka, T | 1 |
| Schneider, PJ | 1 |
| Eytel, CS | 1 |
| Puga, F | 1 |
| Ugarte, JM | 1 |
| Frias, J | 1 |
| Cruz, T | 1 |
| Reboucas, G | 1 |
| Rocha, H | 1 |
| Mioli, V | 1 |
| Zucchelli, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Resistant Hypertension On Treatment - Sequential Nephron Blockade Compared to Dual Blockade of the Renin-angiotensin-aldosterone System Plus Bisoprolol in the Treatment of Resistant Arterial Hypertension: A Randomized Trial (ResHypOT)[NCT02832973] | Phase 4 | 72 participants (Actual) | Interventional | 2015-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for hydrochlorothiazide and Nephrotic Syndrome
| Article | Year |
|---|---|
Effects of muzolimine and of a combination of hydrochlorothiazide/triamterene in healthy subjects and in nephrotic patients.
Topics: Adolescent; Adult; Aged; Body Weight; Creatinine; Drug Therapy, Combination; Electrolytes; Female; H | 1985 |
A controlled clinical trial comparing the diuretic furosemide and hydrochlorothiazide.
Topics: Clinical Trials as Topic; Furosemide; Heart Failure; Humans; Hydrochlorothiazide; Liver Cirrhosis; N | 1968 |
High doses of spironolactone (Aldactone, SC-14266, Verospirone) alone and in combination with triamterene and-or diuretics in the treatment of refractory edema associated with secondary hyperaldosteronism.
Topics: Adult; Aged; Body Weight; Chlorides; Clinical Trials as Topic; Clopamide; Creatinine; Diet, Sodium-R | 1970 |
26 other studies available for hydrochlorothiazide and Nephrotic Syndrome
| Article | Year |
|---|---|
[The action of hydrochlorothiazide in the treatment of the nephrotic syndrome].
Topics: Hydrochlorothiazide; Nephrotic Syndrome | 1961 |
[Hydrochlorothiazide in the treatment of the hypertensive edemo-nephrotic syndrome].
Topics: Chlorothiazide; Edema; Female; Humans; Hydrochlorothiazide; Hypertension; Nephrotic Syndrome; Pregna | 1960 |
[Balance studies on the electrolyte effect of hydrochlorothiazide in children. Contribution to the mechanism of action of conteben diuresis].
Topics: Child; Diuresis; Electrolytes; Humans; Hydrochlorothiazide; Infant; Nephrotic Syndrome; Thioacetazon | 1960 |
[Observations on nephrotic syndrome in adults].
Topics: Calcium; Humans; Hydrochlorothiazide; Nephrotic Syndrome; Penicillins; Potassium; Spironolactone; Tr | 1963 |
[PROGRESS IN PRACTICAL MEDICINE FROM THE VIEWPOINT OF THE INTERNIST].
Topics: Anemia; Anemia, Hemolytic; Anti-Bacterial Agents; Arthritis; Arthritis, Rheumatoid; Clinical Enzyme | 1963 |
[EFFECTS OF HYDROCHLOROTHIAZIDE ASSOCIATED WITH ALDOSTERONE ANTAGONISTS IN THE THERAPY OF INFANTILE NEPHROTIC EDEMA. II. STUDY OF OSMOLAR CLEARANCES AND FREE WATER].
Topics: Child; Diuresis; Edema; Glomerulonephritis; Humans; Hydrochlorothiazide; Ketones; Kidney Function Te | 1963 |
[EFFECTS OF HYDROCHLOROTHIAZIDE ASSOCIATED WITH ALDOSTERONE IN THE THERAPY OF NEPHROTIC EDEMA. I. CLINICAL RESULTS AND STUDY OF WATER AND SALT METABOLISM IN 3 CASES].
Topics: Adrenocorticotropic Hormone; Aldosterone; Child; Edema; Glomerulonephritis; Humans; Hydrochlorothiaz | 1963 |
[STUDIES OF THE PATHOGENESIS AND THERAPY OF INFANTILE NEPHROTIC EDEMA. OBSERVATIONS ON 8 CASES TREATED WITH COMBINED HYDROCHLOROTHIAZIDE AND ALDOSTERONE ANTAGONISTS].
Topics: Child; Diuretics; Edema; Electrolytes; Humans; Hydrochlorothiazide; Kidney Function Tests; Metabolis | 1963 |
THE DIURETIC RESPONSE TO FRUSEMIDE.
Topics: Chlorides; Diuretics; Fluids and Secretions; Furosemide; Heart Failure; Humans; Hydrochlorothiazide; | 1964 |
ETHACRYNIC ACID IN PATHOLOGICAL FLUID RETENTION.
Topics: Digoxin; Diuretics; Drug Therapy; Ethacrynic Acid; Geriatrics; Heart Failure; Humans; Hydrochlorothi | 1965 |
[Clinical study of the diuretic action of hydrochlorothiazide].
Topics: Biomedical Research; Chlorothiazide; Diuretics; Heart Failure; Hydrochlorothiazide; Nephrotic Syndro | 1959 |
[Action of hydrochlorothiazide on nephrotic proteinuria].
Topics: Body Fluids; Chlorothiazide; Humans; Hydrochlorothiazide; Nephrotic Syndrome; Proteinuria; Urinalysi | 1961 |
The nephrotic syndrome: current concepts in diagnosis and therapy advantages of alternate day steroid regimen.
Topics: Alkylating Agents; Anti-Bacterial Agents; Child; Child, Preschool; Ethacrynic Acid; Humans; Hydralaz | 1967 |
Polythiazide as a diuretic. A clinical trial.
Topics: Adolescent; Adult; Aged; Edema; Female; Heart Failure; Humans; Hydrochlorothiazide; Liver Cirrhosis; | 1967 |
Sequential nephron blockade breaks resistance to diuretics in edematous states.
Topics: Acetazolamide; Adult; Ascites; Diuresis; Diuretics; Edema; Female; Furosemide; Heart Failure; Humans | 1997 |
Pharmacokinetic and pharmacodynamic interactions between furosemide and hydrochlorothiazide in nephrotic patients.
Topics: Drug Interactions; Erythrocytes; Female; Furosemide; Humans; Hydrochlorothiazide; Male; Middle Aged; | 1988 |
Nephrotic syndrome associated with bacteraemia after shunt operations for hydrocephalus.
Topics: Edema; Escherichia coli; Female; Fluorescent Antibody Technique; Glomerulonephritis; Humans; Hydroce | 1965 |
[The nephrotic syndrome, clinical features and therapy].
Topics: Adrenocorticotropic Hormone; Adult; Humans; Hydrochlorothiazide; Male; Nephrotic Syndrome; Penicilli | 1965 |
[Therapy of the nephrotic syndrome].
Topics: Adrenocorticotropic Hormone; Azathioprine; Chlorambucil; Chlorthalidone; Diet, Sodium-Restricted; Di | 1968 |
Value and toxicity of therapy for idiopathic nephrotic syndrome in the child.
Topics: Anti-Bacterial Agents; Blood Protein Disorders; Child; Chlorothiazide; Cyclophosphamide; Diet, Sodiu | 1973 |
Hyperkalemia and coma associated with renal tubular acidosis in an old patient with refractory edema due to the nephrotic syndrome: furosemide-bicarbonate therapy.
Topics: Acidosis, Renal Tubular; Adrenal Cortex Hormones; Aged; Aldosterone; Bicarbonates; Coma; Edema; Furo | 1972 |
Clinical evaluations of a combined application of amiloride (MK-870) and thiazide.
Topics: Adult; Blood Pressure; Diuretics; Female; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; | 1969 |
The nephrotic syndrome in an elderly woman. An unusual association with an unusual response to therapy.
Topics: Aged; Biopsy; Body Weight; Chronic Disease; Diagnosis, Differential; Edema; Female; Humans; Hydrochl | 1969 |
[Rapid spread of edema in the nephrotic syndrome].
Topics: Blood Transfusion; Child; Diuretics; Humans; Hydrochlorothiazide; Nephrotic Syndrome | 1965 |
Fatal strongyloidiasis in patients receiving corticosteroids.
Topics: Adult; Aminosalicylic Acids; Child; Child, Preschool; Cyclophosphamide; Dexamethasone; Diet, Sodium- | 1966 |
[The clinical use of an association of hydrochlorothiazide and triamterene in nephrotic syndromes].
Topics: Adolescent; Adult; Aged; Amyloidosis; Child; Diabetic Nephropathies; Diuresis; Electrolytes; Female; | 1966 |