hydrochlorothiazide has been researched along with Nephrocalcinosis in 13 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
Nephrocalcinosis: A condition characterized by calcification of the renal tissue itself. It is usually seen in distal RENAL TUBULAR ACIDOSIS with calcium deposition in the DISTAL KIDNEY TUBULES and the surrounding interstitium. Nephrocalcinosis causes RENAL INSUFFICIENCY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hydrochlorothiazide (HCT) is applied in the therapy of familial hypomagnesaemia with hypercalciuria and nephrocalcinosis (FHHNC) caused by claudin-16 (CLDN16) mutation." | 5.12 | Hydrochlorothiazide in CLDN16 mutation. ( Dötsch, J; Gravou-Apostolatou, C; Konrad, M; Plank, C; Rascher, W; Stöhr, W; Zimmermann, B, 2006) |
| "The effect of hydrochlorothiazide (HCTZ) on clinical and radiologic progression of nephrocalcinosis was evaluated in 11 children with XLH." | 5.09 | Thiazide diuretics arrest the progression of nephrocalcinosis in children with X-linked hypophosphatemia. ( Baum, M; Seikaly, MG, 2001) |
| "Treatment with hydrochlorothiazide is effective in patients without increased urinary excretion of prostaglandin, whereas patients with increased prostaglandin excretion respond better to indomethacin therapy." | 1.27 | [Clinical variants of idiopathic hypercalciuria in children]. ( Bachmann, H; Kohout, I, 1987) |
| "Significant progress of nephrolithiasis and nephrocalcinosis was observed in 80% of patients with permanent hypomagnesemia and in 4% of patients with normalization of serum magnesium level." | 1.27 | Prognosis of urolithiasis and nephrocalcinosis in hypomagnesemia. ( Karlíková, L; Revúsová, V; Suchánek, B; Zvara, V, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (61.54) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wolf, MT | 1 |
| Dötsch, J | 2 |
| Konrad, M | 2 |
| Böswald, M | 1 |
| Rascher, W | 2 |
| FANCONI, A | 1 |
| Auron, A | 1 |
| Alon, US | 1 |
| Zimmermann, B | 1 |
| Plank, C | 1 |
| Stöhr, W | 1 |
| Gravou-Apostolatou, C | 1 |
| Gremske, D | 1 |
| Brien, G | 1 |
| Bick, C | 1 |
| Nimmergut, S | 1 |
| Seikaly, MG | 1 |
| Baum, M | 1 |
| Bald, M | 1 |
| Vester, U | 1 |
| Wingen, AM | 1 |
| Sztriha, L | 1 |
| Beviz, J | 1 |
| Aggarwal, VK | 1 |
| Jones, KV | 1 |
| Kohout, I | 1 |
| Bachmann, H | 1 |
| Atkinson, SA | 1 |
| Shah, JK | 1 |
| McGee, C | 1 |
| Steele, BT | 1 |
| Revúsová, V | 1 |
| Zvara, V | 1 |
| Karlíková, L | 1 |
| Suchánek, B | 1 |
| Sörgel, F | 1 |
| Ettinger, B | 1 |
| Benet, LZ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Calciuric Effect and Cyclic Parenteral Nutrition in Preterm Infants[NCT00711763] | 1 participants (Actual) | Observational | 2008-07-31 | Terminated (stopped due to failure to recruit more patients and lack of supporting personnel.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for hydrochlorothiazide and Nephrocalcinosis
| Article | Year |
|---|---|
Hydrochlorothiazide in CLDN16 mutation.
Topics: Adolescent; Adult; Calcium; Child; Child, Preschool; Claudins; Creatinine; Dose-Response Relationshi | 2006 |
Thiazide diuretics arrest the progression of nephrocalcinosis in children with X-linked hypophosphatemia.
Topics: Calcium; Child; Disease Progression; Diuretics; Female; Humans; Hydrochlorothiazide; Hypophosphatemi | 2001 |
11 other studies available for hydrochlorothiazide and Nephrocalcinosis
| Article | Year |
|---|---|
Follow-up of five patients with FHHNC due to mutations in the Paracellin-1 gene.
Topics: Calcium; Child; Child, Preschool; Claudins; Diuretics; Female; Follow-Up Studies; Growth; Humans; Hy | 2002 |
[IDIOPATHIC HYPERCALCIURIA IN CHILDHOOD].
Topics: Body Fluids; Calcium Metabolism Disorders; Child; Humans; Hydrochlorothiazide; Hypercalciuria; Kidne | 1963 |
Resolution of medullary nephrocalcinosis in children with metabolic bone disorders.
Topics: Adolescent; Amiloride; Child; Humans; Hydrochlorothiazide; Hypophosphatasia; Hypophosphatemia, Famil | 2005 |
[Distal form of renal tubular acidosis and nephrolithiasis].
Topics: Acidosis; Ethacrynic Acid; Humans; Hydrochlorothiazide; Kidney Calculi; Kidney Tubules; Kidney Tubul | 1980 |
Dent's disease.
Topics: Calcium; Diuretics; Humans; Hydrochlorothiazide; Hypokalemia; Kidney Diseases; Kidney Failure, Chron | 2002 |
[Idiopathic hypercalcaemia. The effect of hypercalcaemia on renal function (author's transl)].
Topics: Humans; Hydrochlorothiazide; Hypercalcemia; Infant; Kidney Diseases; Male; Nephrocalcinosis; Prednis | 1979 |
Diffuse nephrocalcinosis and idiopathic renal hypercalciuria.
Topics: Calcium; Child; Enuresis; Humans; Hydrochlorothiazide; Male; Nephrocalcinosis; Ultrasonography; Urog | 1989 |
[Clinical variants of idiopathic hypercalciuria in children].
Topics: Aldosterone; Calcium; Child; Child, Preschool; Dinoprostone; Female; Humans; Hydrochlorothiazide; Hy | 1987 |
Mineral excretion in premature infants receiving various diuretic therapies.
Topics: Birth Weight; Bone Diseases, Metabolic; Diuretics; Drug Therapy, Combination; Female; Furosemide; Hu | 1988 |
Prognosis of urolithiasis and nephrocalcinosis in hypomagnesemia.
Topics: Adolescent; Adult; Aged; Allopurinol; Cation Exchange Resins; Cellulose; Child; Child, Preschool; Ci | 1985 |
Metabolic fate and solubility of triamterene--not an explanation for triamterene nephrolithiasis.
Topics: Adult; Buffers; Chromatography, Thin Layer; Humans; Hydrochlorothiazide; Hydrogen-Ion Concentration; | 1986 |