hydrochlorothiazide has been researched along with Necrosis in 10 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Two animals were kept in a hypokalemic state from day 3 of dosing on, and their mean plasma potassium levels were 2." | 5.35 | Myocardial necrosis related to hydrochlorothiazide-induced hypokalemia in cynomolgus monkeys. ( Izumisawa, N; Kajikawa, S; Matsumoto, M; Nakatsuji, S; Oishi, Y; Shirakawa, T; Tabata, H; Takeuchi, A; Toyoda, Y; Watanabe, K, 2008) |
| "Previous studies have shown that oral administration of minoxidil on 2 consecutive days produces an increase in heart rate and myocardial necrosis in Beagle dogs." | 3.66 | Divergent effects of propranolol and furosemide pretreatment on acute cardiomyopathy induced by minoxidil in beagle dogs. ( Balazs, T; Ferrans, VJ; Herman, EH; Young, RS, 1981) |
| "The pancreatitis was first manifested by panniculitis of the lower extremities." | 1.27 | Childhood systemic lupus erythematosus. Association with pancreatitis, subcutaneous fat necrosis, and calcinosis cutis. ( Gorman, H; Penneys, N; Schachner, L; Simons-Ling, N; Strauss, J; Zillereulo, G, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (70.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takeuchi, A | 1 |
| Shirakawa, T | 1 |
| Toyoda, Y | 1 |
| Tabata, H | 1 |
| Kajikawa, S | 1 |
| Izumisawa, N | 1 |
| Matsumoto, M | 1 |
| Nakatsuji, S | 1 |
| Watanabe, K | 1 |
| Oishi, Y | 1 |
| KJELLBO, H | 1 |
| STAKEBERG, H | 1 |
| MELLGREN, J | 1 |
| Long, RC | 1 |
| Wofford, MR | 1 |
| Harkins, KG | 1 |
| Minor, DS | 1 |
| Hall, CE | 1 |
| Holland, OB | 1 |
| Hall, O | 1 |
| Simons-Ling, N | 1 |
| Schachner, L | 1 |
| Penneys, N | 1 |
| Gorman, H | 1 |
| Zillereulo, G | 1 |
| Strauss, J | 1 |
| Herman, EH | 1 |
| Balazs, T | 1 |
| Ferrans, VJ | 1 |
| Young, RS | 1 |
| Contard, F | 1 |
| Sabri, A | 1 |
| Glukhova, M | 1 |
| Sartore, S | 1 |
| Marotte, F | 1 |
| Pomies, JP | 1 |
| Schiavi, P | 1 |
| Guez, D | 1 |
| Samuel, JL | 1 |
| Rappaport, L | 1 |
| Schweitzer, IL | 1 |
| Peters, RL | 1 |
| Selye, H | 2 |
| Somogyi, A | 1 |
| Savoie, L | 1 |
10 other studies available for hydrochlorothiazide and Necrosis
| Article | Year |
|---|---|
Myocardial necrosis related to hydrochlorothiazide-induced hypokalemia in cynomolgus monkeys.
Topics: Animals; Biomarkers; Diuretics; Electrocardiography; Female; Hydrochlorothiazide; Hypokalemia; Macac | 2008 |
POSSIBLY THIAZIDE-INDUCED RENAL NECROTISING VASCULITIS.
Topics: Chlorothiazide; Hydrochlorothiazide; Inflammation; Kidney Diseases; Necrosis; Pathology; Skin Diseas | 1965 |
Hepatocellular necrosis associated with labetalol.
Topics: Antihypertensive Agents; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Inj | 2007 |
Evolution of adrenal regeneration hypertension in rats with actively regenerating or fully regenerated glands.
Topics: Adrenal Glands; Aging; Animals; Blood Pressure; Body Weight; Diet; Drinking; Female; Heart; Hydrochl | 1967 |
Childhood systemic lupus erythematosus. Association with pancreatitis, subcutaneous fat necrosis, and calcinosis cutis.
Topics: Adipose Tissue; Azathioprine; Calcinosis; Child; Female; Humans; Hydrochlorothiazide; Lupus Erythema | 1983 |
Divergent effects of propranolol and furosemide pretreatment on acute cardiomyopathy induced by minoxidil in beagle dogs.
Topics: Animals; Dogs; Drug Interactions; Furosemide; Heart Diseases; Heart Rate; Hydrochlorothiazide; Male; | 1981 |
Arterial smooth muscle cell phenotype in stroke-prone spontaneously hypertensive rats.
Topics: Actins; Animals; Aorta, Thoracic; Cerebral Cortex; Cerebrovascular Disorders; Fibronectins; Hydrochl | 1993 |
Acute submassive hepatic necrosis due to methyldopa. A case demonstrating possible initiation of chronic liver disease.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Biopsy, Needle; Chemical and Drug Induced Liver I | 1974 |
Prevention of stress-induced cardiac necrosis by amiloride.
Topics: Animals; Diuretics; Ethacrynic Acid; Female; Heart Diseases; Hydrochlorothiazide; Immobilization; My | 1969 |
Effect of various diuretics upon experimental cardiac necrosis.
Topics: Adrenal Cortex Hormones; Animals; Diuretics; Ethacrynic Acid; Guanidines; Heart Diseases; Hydrochlor | 1969 |