hydrochlorothiazide has been researched along with Liddle Syndrome in 3 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
Liddle Syndrome: Familial pseudoaldosteronism characterized by autosomal dominant inheritance of hypertension with HYPOKALEMIA; ALKALOSIS; RENIN and ALDOSTERONE level decreases. It is caused by mutations in EPITHELIAL SODIUM CHANNELS beta and gamma subunits. Different mutations in the same EPITHELIAL SODIUM CHANNELS subunits can cause PSEUDOHYPOALDOSTERONISM, TYPE I, AUTOSOMAL DOMINANT.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fan, P | 1 |
| Zhao, YM | 1 |
| Zhang, D | 1 |
| Liao, Y | 1 |
| Yang, KQ | 1 |
| Tian, T | 1 |
| Lou, Y | 1 |
| Luo, F | 1 |
| Ma, WJ | 1 |
| Zhang, HM | 1 |
| Song, L | 1 |
| Cai, J | 1 |
| Liu, YX | 1 |
| Zhou, XL | 1 |
| Nasr, SH | 1 |
| Milliner, DS | 1 |
| Wooldridge, TD | 1 |
| Sethi, S | 1 |
| Polfus, LM | 1 |
| Boerwinkle, E | 1 |
| Gibbs, RA | 1 |
| Metcalf, G | 1 |
| Muzny, D | 1 |
| Veeraraghavan, N | 1 |
| Grove, M | 1 |
| Shete, S | 1 |
| Wallace, S | 1 |
| Milewicz, D | 1 |
| Hanchard, N | 1 |
| Lupski, JR | 1 |
| Hashmi, SS | 1 |
| Gupta-Malhotra, M | 1 |
3 other studies available for hydrochlorothiazide and Liddle Syndrome
| Article | Year |
|---|---|
A Novel Frameshift Mutation of SCNN1G Causing Liddle Syndrome with Normokalemia.
Topics: Adolescent; Aged; Amiloride; Antihypertensive Agents; Biomarkers; Blood Pressure; Child; Drug Combin | 2019 |
Triamterene crystalline nephropathy.
Topics: Antihypertensive Agents; Biopsy; Creatinine; Diagnostic Errors; Drug Combinations; Drug-Related Side | 2014 |
Whole-exome sequencing reveals an inherited R566X mutation of the epithelial sodium channel β-subunit in a case of early-onset phenotype of Liddle syndrome.
Topics: Adult; Aldosterone; Alleles; Amiloride; Child, Preschool; Epithelial Sodium Channels; Exome; Exome S | 2016 |