hydrochlorothiazide has been researched along with Kidney Failure in 10 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
Kidney Failure: A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The long-term effects of indapamide or hydrochlorothiazide on blood presssure and renal function were examined in patents with impaired renal function and moderate hypertension." | 9.08 | Indapamide is superior to thiazide in the preservation of renal function in patients with renal insufficiency and systemic hypertension. ( Gadallah, M; Madkour, H; Massry, SG; Plante, GE; Riveline, B, 1996) |
| "A single blind crossover study with washout phases showed that pyrazinoylguanidine (PZG) reduced elevated serum concentrations of urea, triglycerides, and cholesterol in patients with renal insufficiency." | 7.68 | Contrasting effects of pyrazinoylguanidine and hydrochlorothiazide in patients with renal insufficiency. ( Beyer, KH; Gelarden, RT; Knutson, DW; Vary, JE; Vesell, ES; Ward, TD, 1993) |
| "Hydrochlorothiazide (HCTZ) is a thiazide diuretic used for the treatment of hypertension and edema associated with fluid overload conditions such as congestive heart failure (CHF)." | 5.17 | Population-based meta-analysis of hydrochlorothiazide pharmacokinetics. ( Mager, DE; Mallikaarjun, S; Shoaf, SE; Van Wart, SA, 2013) |
| "The long-term effects of indapamide or hydrochlorothiazide on blood presssure and renal function were examined in patents with impaired renal function and moderate hypertension." | 5.08 | Indapamide is superior to thiazide in the preservation of renal function in patients with renal insufficiency and systemic hypertension. ( Gadallah, M; Madkour, H; Massry, SG; Plante, GE; Riveline, B, 1996) |
| "This review focuses on the role of the fixed-dose combination (FDC) drug valsartan/hydrochlorothiazide (HCTZ) in the treatment of hypertension." | 4.87 | Valsartan plus hydrochlorothiazide: a review of its use since its introduction. ( Bains, J; Smith, WB, 2011) |
| "A single blind crossover study with washout phases showed that pyrazinoylguanidine (PZG) reduced elevated serum concentrations of urea, triglycerides, and cholesterol in patients with renal insufficiency." | 3.68 | Contrasting effects of pyrazinoylguanidine and hydrochlorothiazide in patients with renal insufficiency. ( Beyer, KH; Gelarden, RT; Knutson, DW; Vary, JE; Vesell, ES; Ward, TD, 1993) |
| " Safety was assessed in both studies by the incidence of adverse experiences." | 2.71 | Pharmacokinetics, safety, and antihypertensive efficacy of losartan in combination with hydrochlorothiazide in hypertensive patients with renal impairment. ( Dickson, TZ; Lin, CC; Lo, MW; Ramjit, D; Ritter, MA; Shahinfar, S; Snavely, D; Zagrobelny, J, 2003) |
| " Non-compartmental pharmacokinetic parameters of fosinoprilat and HCTZ were determined from blood and urine samples obtained over 48 h starting on Day 1 (single dose) and Day 5 (steady state): maximum serum concentration (Cmax ), time to maximum serum concentration (tmax ), area under the serum concentration-time curve during the dosing interval (AUC), cumulative urinary excretion (CUE) and the accumulation index (AI; ratio of AUC-day 5/AUC-day 1)." | 2.69 | Fosinopril/hydrochlorothiazide: single dose and steady-state pharmacokinetics and pharmacodynamics. ( Lins, R; Mangold, B; O'Grady, P; Yee, KF, 1999) |
| "In 562 patients with ADPKD (61% female, eGFR 63±28 ml/min per 1." | 1.91 | Prostaglandin E2, Osmoregulation, and Disease Progression in Autosomal Dominant Polycystic Kidney Disease. ( Fenton, RA; Gansevoort, RT; Geurts, F; Hoorn, EJ; Kramers, BJ; Meijer, E; Salih, M; Xue, L; Zietse, R, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Geurts, F | 1 |
| Xue, L | 1 |
| Kramers, BJ | 1 |
| Zietse, R | 1 |
| Gansevoort, RT | 1 |
| Fenton, RA | 1 |
| Meijer, E | 1 |
| Salih, M | 1 |
| Hoorn, EJ | 1 |
| Van Wart, SA | 1 |
| Shoaf, SE | 1 |
| Mallikaarjun, S | 1 |
| Mager, DE | 1 |
| Bains, J | 1 |
| Smith, WB | 1 |
| Dickson, TZ | 1 |
| Zagrobelny, J | 1 |
| Lin, CC | 1 |
| Ritter, MA | 1 |
| Snavely, D | 1 |
| Ramjit, D | 1 |
| Shahinfar, S | 1 |
| Lo, MW | 1 |
| SHULGA, IuD | 1 |
| GELFAND, ML | 1 |
| GARREN, MG | 1 |
| ROWAN, RL | 1 |
| Mahmood, I | 1 |
| Beyer, KH | 1 |
| Ward, TD | 1 |
| Vary, JE | 1 |
| Gelarden, RT | 1 |
| Knutson, DW | 1 |
| Vesell, ES | 1 |
| Madkour, H | 1 |
| Gadallah, M | 1 |
| Riveline, B | 1 |
| Plante, GE | 1 |
| Massry, SG | 1 |
| O'Grady, P | 1 |
| Yee, KF | 1 |
| Lins, R | 1 |
| Mangold, B | 1 |
1 review available for hydrochlorothiazide and Kidney Failure
| Article | Year |
|---|---|
Valsartan plus hydrochlorothiazide: a review of its use since its introduction.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Diuretics; Drug Combinati | 2011 |
5 trials available for hydrochlorothiazide and Kidney Failure
| Article | Year |
|---|---|
Population-based meta-analysis of hydrochlorothiazide pharmacokinetics.
Topics: Adult; Antihypertensive Agents; Benzazepines; Diuretics; Heart Failure; Humans; Hydrochlorothiazide; | 2013 |
Pharmacokinetics, safety, and antihypertensive efficacy of losartan in combination with hydrochlorothiazide in hypertensive patients with renal impairment.
Topics: Antihypertensive Agents; Area Under Curve; Drug Administration Schedule; Drug Therapy, Combination; | 2003 |
Center specificity in the limited sampling model (LSM): can the LSM developed from healthy subjects be extended to disease states?
Topics: Antihypertensive Agents; Area Under Curve; Benzimidazoles; Benzoates; Blood Specimen Collection; Com | 2003 |
Indapamide is superior to thiazide in the preservation of renal function in patients with renal insufficiency and systemic hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Diuretics; Female; Humans; Hydrochlorothiazide; Hypertension; | 1996 |
Fosinopril/hydrochlorothiazide: single dose and steady-state pharmacokinetics and pharmacodynamics.
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pr | 1999 |
4 other studies available for hydrochlorothiazide and Kidney Failure
| Article | Year |
|---|---|
Prostaglandin E2, Osmoregulation, and Disease Progression in Autosomal Dominant Polycystic Kidney Disease.
Topics: Antidiuretic Hormone Receptor Antagonists; Dinoprostone; Disease Progression; Female; Glomerular Fil | 2023 |
[APPLICATION OF HYPOTHIAZIDE IN CHRONIC KIDNEY DISEASES].
Topics: Acute Kidney Injury; Blood Chemical Analysis; Glomerulonephritis; Hydrochlorothiazide; Hypertension; | 1963 |
ACUTE ANURIA ASSOCIATED WITH CHLOROTHIAZIDE AND HYDROCHLOROTHIAZIDE THERAPY: RECOVERY.
Topics: Acute Kidney Injury; Anuria; Chlorothiazide; Diabetes Mellitus; Digoxin; Geriatrics; Gout; Hydrochlo | 1964 |
Contrasting effects of pyrazinoylguanidine and hydrochlorothiazide in patients with renal insufficiency.
Topics: Adult; Aged; Blood Glucose; Cholesterol; Electrolytes; Female; Guanidines; Humans; Hydrochlorothiazi | 1993 |