hydrochlorothiazide has been researched along with Kidney Diseases in 100 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acetazolamide and hydrochlorothiazide followed by furosemide is more effective than furosemide and hydrochlorothiazide followed by furosemide for the treatment of refractory nephrotic edema." | 9.24 | Acetazolamide and Hydrochlorothiazide Followed by Furosemide Versus Furosemide and Hydrochlorothiazide Followed by Furosemide for the Treatment of Adults With Nephrotic Edema: A Randomized Trial. ( Dormanesh, B; Fallahzadeh, MA; Fallahzadeh, MH; Fallahzadeh, MK; Roozbeh, J; Sagheb, MM, 2017) |
| "Furosemide is the diuretic of choice for the treatment of hypertension in chronic kidney disease but the adaptative changes in the distal nephron may decrease its efficacy." | 9.16 | A pilot study comparing furosemide and hydrochlorothiazide in patients with hypertension and stage 4 or 5 chronic kidney disease. ( Berland, Y; Dussol, B; Morange, S; Moussi-Frances, J; Mundler, O; Somma-Delpero, C, 2012) |
| "Zofenopril, is a highly lipophilic ACE inhibitor, characterized by long-lasting tissue penetration and sustained cardiac ACE inhibition, indicated for the treatment of hypertension and myocardial infarction." | 8.85 | Zofenopril plus hydrochlorothiazide fixed combination in the treatment of hypertension and associated clinical conditions. ( Malacco, E; Omboni, S; Parati, G, 2009) |
| "Four boys with classical nephrogenic diabetes insipidus have been treated by indomethacin, by hydrochlorothiazide, and by the combination of indomethacin and hydrochlorothiazide." | 7.67 | Response to indomethacin and hydrochlorothiazide in nephrogenic diabetes insipidus. ( Jonkman, A; Monnens, L; Thomas, C, 1984) |
| "In four boys with congenital nephrogenic diabetes insipidus, plasma arginine-vasopressin (AVP) and urinary excretion of prostaglandins were studied in response to treatment with hydrochlorothiazide and indomethacin." | 7.67 | Congenital nephrogenic diabetes insipidus-vasopressin and prostaglandins in response to treatment with hydrochlorothiazide and indomethacin. ( Henrichs, IA; Maier, R; Rascher, W; Rosendahl, W; Seyberth, HW, 1987) |
| "Acetazolamide and hydrochlorothiazide followed by furosemide is more effective than furosemide and hydrochlorothiazide followed by furosemide for the treatment of refractory nephrotic edema." | 5.24 | Acetazolamide and Hydrochlorothiazide Followed by Furosemide Versus Furosemide and Hydrochlorothiazide Followed by Furosemide for the Treatment of Adults With Nephrotic Edema: A Randomized Trial. ( Dormanesh, B; Fallahzadeh, MA; Fallahzadeh, MH; Fallahzadeh, MK; Roozbeh, J; Sagheb, MM, 2017) |
| "A total of 439 hypertensive patients with metabolic syndrome and/or diabetes mellitus were randomized to 2 groups: group 1--ramipril (ACE-I) or perindopril and group 2--losartan (ARB)." | 5.19 | Anti-hypertensive strategies in patients with MEtabolic parameters, DIabetes mellitus and/or NephropAthy (the M E D I N A study). ( Soucek, M; Spinar, J; Vitovec, J, 2014) |
| "Furosemide is the diuretic of choice for the treatment of hypertension in chronic kidney disease but the adaptative changes in the distal nephron may decrease its efficacy." | 5.16 | A pilot study comparing furosemide and hydrochlorothiazide in patients with hypertension and stage 4 or 5 chronic kidney disease. ( Berland, Y; Dussol, B; Morange, S; Moussi-Frances, J; Mundler, O; Somma-Delpero, C, 2012) |
| "0] g/24 h proteinuria) were treated during 6-week periods with placebo, ARB (100 mg/d losartan), and ARB plus diuretics (100 mg/d losartan plus 25 mg/d hydrochlorothiazide) combined with consecutively regular and low sodium diets (193 ± 62 versus 93 ± 52 mmol Na(+)/d)." | 5.15 | Effects of antiproteinuric intervention on elevated connective tissue growth factor (CTGF/CCN-2) plasma and urine levels in nondiabetic nephropathy. ( Goldschmeding, R; Hemmelder, MH; Laverman, GD; Navis, G; Nguyen, TQ; Slagman, MC; Vogt, L; Waanders, F, 2011) |
| "Urinary KIM-1 level was increased in patients with nondiabetic CKD with proteinuria and decreased in parallel with proteinuria by using losartan, sodium restriction, their combination, losartan plus HCT, and the latter plus sodium restriction." | 5.14 | Effect of renin-angiotensin-aldosterone system inhibition, dietary sodium restriction, and/or diuretics on urinary kidney injury molecule 1 excretion in nondiabetic proteinuric kidney disease: a post hoc analysis of a randomized controlled trial. ( Bonventre, JV; Damman, K; Hamming, I; Leuvenink, H; Navis, G; Vaidya, VS; van Goor, H; Vogt, L; Waanders, F, 2009) |
| " In controlled trials, 2249 subjects, who included normal volunteers and patients with hypertension and congestive heart failure, have received enalapril alone or concomitantly with hydrochlorothiazide or other antihypertensive agents." | 5.05 | Overall tolerance and safety of enalapril. ( Kulaga, SF; McFate Smith, W; Moncloa, F; Pingeon, R; Walker, JF, 1984) |
| " These initial studies demonstrate that tienilic acid is safe and effective in the treatment of mild to moderate essential hypertension, salt and water retention states, including oedema associated with congestive cardiac failure or mild to moderate renal dysfunction, and in the management of elevated serum uric acid levels associated with gout." | 5.04 | Safety of tienilic acid. ( Beg, MA; Ragland, R, 1979) |
| "Zofenopril, is a highly lipophilic ACE inhibitor, characterized by long-lasting tissue penetration and sustained cardiac ACE inhibition, indicated for the treatment of hypertension and myocardial infarction." | 4.85 | Zofenopril plus hydrochlorothiazide fixed combination in the treatment of hypertension and associated clinical conditions. ( Malacco, E; Omboni, S; Parati, G, 2009) |
| "To evaluate the therapeutic effect of hydrochlorothiazide in idiopathic renal hypercalciuria." | 3.77 | Low-dose thiazide diuretics in children with idiopathic renal hypercalciuria. ( Choi, JN; Lee, JS; Shin, JI, 2011) |
| "Four boys with classical nephrogenic diabetes insipidus have been treated by indomethacin, by hydrochlorothiazide, and by the combination of indomethacin and hydrochlorothiazide." | 3.67 | Response to indomethacin and hydrochlorothiazide in nephrogenic diabetes insipidus. ( Jonkman, A; Monnens, L; Thomas, C, 1984) |
| "In four boys with congenital nephrogenic diabetes insipidus, plasma arginine-vasopressin (AVP) and urinary excretion of prostaglandins were studied in response to treatment with hydrochlorothiazide and indomethacin." | 3.67 | Congenital nephrogenic diabetes insipidus-vasopressin and prostaglandins in response to treatment with hydrochlorothiazide and indomethacin. ( Henrichs, IA; Maier, R; Rascher, W; Rosendahl, W; Seyberth, HW, 1987) |
| " We conclude that although the pharmacokinetics of both enalaprilat and HCTZ are related to renal function, HCTZ has no significant effect on the pharmacokinetics of enalaprilat and that dosage adjustment for both regimens should be based on renal function." | 2.68 | Effect of hydrochlorothiazide on the pharmacokinetics of enalapril in hypertensive patients with varying renal function. ( Carmody, M; Doyle, GD; Hersh, AD; Kelly, JG; Laher, MS, 1996) |
| " Similar differences have been reported for such patient groups when the drugs were administered separately, indicating an absence of pharmacokinetic interaction." | 2.67 | The effects of age and renal impairment on the pharmacokinetics of co-administered lisinopril and hydrochlorothiazide. ( Connell, PA; Hosie, J; Laher, MS; Mulkerrins, E; Smith, RP; Swaisland, AJ, 1991) |
| " The third-generation liphophilic angiotensin converting enzyme inhibitor zofenopril, administered alone or combined with a thiazide diuretic, has proved to be effective in lowering blood pressure in hypertensive patients and to reduce the risk of fatal and non-fatal events in post-acute myocardial infarction and heart failure." | 2.61 | Efficacy of Zofenopril Alone or in Combination with Hydrochlorothiazide in Patients with Kidney Dysfunction. ( Borghi, C; Omboni, S, 2019) |
| "The differential diagnosis of pulmonary disease should include drug toxicity, progression of the primary illness, and opportunistic infection." | 2.42 | Infiltrative lung disease due to noncytotoxic agents. ( Cooper, JA; Eggert, M; Lock, BJ, 2004) |
| "Acute lymphoblastic leukemia (ALL) in children can rarely present with severe lactic acidosis in the absence of a high white blood cell count or other complications." | 1.32 | Acute lymphoblastic leukemia presenting with lactic acidosis and renal tubular dysfunction. ( Hayek, M; Srinivasan, A, 2003) |
| "Renal cell carcinoma has been linked to hypertension and antihypertensive medications." | 1.29 | Renal cell carcinoma and thiazide use: a historical, case-control study (California, USA). ( Hiatt, RA; Quesenberry, CP; Tolan, K, 1994) |
| " In 2-year studies using dietary concentrations of 0, 250, 500 and 2000 ppm in rats and 0, 2500 and 5000 ppm in mice, survival of dosed and control groups of rats and mice was similar, as were body weights of mice." | 1.28 | Toxicology and carcinogenicity studies of diuretics in F344 rats and B6C3F1 mice. 1. Hydrochlorothiazide. ( Bucher, JR; Davis, WE; Elwell, MR; Eustis, SL; Haseman, JK; Huff, J; Meierhenry, EF, 1990) |
| " Very slight accumulation of sotalol and hydrochlorothiazide was observed, so it appears unnecessary to reduce the dosage in patients with a creatinine clearance of 30 ml/min or more." | 1.27 | Pharmacokinetics of a fixed combination of sotalol and hydrochlorothiazide in hypertensive patients with moderate renal insufficiency. ( Fillastre, JP; Fourtillan, JB; Ingrand, I; Kher, A; Lefebvre, MA, 1984) |
| " The half-life of elimination increased from 6." | 1.27 | Pharmacokinetics of hydrochlorothiazide in relation to renal function. ( Hasenfuss, G; Knauf, H; Mutschler, E; Niemeyer, C; Schäfer-Korting, M; Wais, U, 1983) |
| "Allopurinol toxicity has been associated with the use of this drug in patients with renal insufficiency, a situation where the half-life of oxipurinol, the major metabolite of allopurinol, is prolonged." | 1.27 | Evaluation of a thiazide-allopurinol drug interaction. ( Hande, KR, 1986) |
| "Treatment with hydrochlorothiazide (50 mg/day) produced a decline in fasting urinary Ca (to 0." | 1.27 | Postmenopausal osteoporosis as a manifestation of renal hypercalciuria with secondary hyperparathyroidism. ( Glass, K; Nicar, MJ; Pak, CY; Sakhaee, K, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 55 (55.00) | 18.7374 |
| 1990's | 7 (7.00) | 18.2507 |
| 2000's | 23 (23.00) | 29.6817 |
| 2010's | 14 (14.00) | 24.3611 |
| 2020's | 1 (1.00) | 2.80 |
| Authors | Studies |
|---|---|
| Avdeef, A | 1 |
| Tam, KY | 1 |
| Cechinel-Zanchett, CC | 1 |
| Bolda Mariano, LN | 1 |
| Boeing, T | 1 |
| da Costa, JC | 1 |
| Da Silva, LM | 1 |
| Bastos, JK | 1 |
| Cechinel-Filho, V | 1 |
| de Souza, P | 1 |
| Wei, SY | 1 |
| Wang, YX | 1 |
| Zhang, QF | 1 |
| Zhao, SL | 1 |
| Diao, TT | 1 |
| Li, JS | 1 |
| Qi, WR | 1 |
| He, YX | 1 |
| Guo, XY | 1 |
| Zhang, MZ | 1 |
| Chen, JY | 1 |
| Wang, XT | 1 |
| Wei, QJ | 1 |
| Wang, Y | 1 |
| Li, B | 1 |
| Omboni, S | 2 |
| Borghi, C | 1 |
| Spinar, J | 1 |
| Vitovec, J | 1 |
| Soucek, M | 1 |
| Fallahzadeh, MA | 1 |
| Dormanesh, B | 1 |
| Fallahzadeh, MK | 1 |
| Roozbeh, J | 1 |
| Fallahzadeh, MH | 1 |
| Sagheb, MM | 1 |
| Waanders, F | 3 |
| Vaidya, VS | 1 |
| van Goor, H | 1 |
| Leuvenink, H | 1 |
| Damman, K | 1 |
| Hamming, I | 1 |
| Bonventre, JV | 1 |
| Vogt, L | 3 |
| Navis, G | 3 |
| Renke, M | 2 |
| Tylicki, L | 2 |
| Knap, N | 1 |
| Rutkowski, P | 2 |
| Neuwelt, A | 1 |
| Larczynski, W | 2 |
| Wozniak, M | 1 |
| Rutkowski, B | 2 |
| Perico, N | 1 |
| Cattaneo, D | 1 |
| Remuzzi, G | 2 |
| Krikken, JA | 1 |
| Dallinga-Thie, GM | 1 |
| Dikkeschei, LD | 1 |
| Navis, GJ | 1 |
| Dullaart, RP | 1 |
| Abe, M | 2 |
| Okada, K | 2 |
| Maruyama, T | 2 |
| Matsumoto, K | 2 |
| Malacco, E | 1 |
| Parati, G | 1 |
| Thornton, SN | 1 |
| Slagman, MC | 2 |
| Laverman, GD | 2 |
| Okano, Y | 1 |
| Toya, Y | 1 |
| Azuma, K | 1 |
| Yabana, M | 1 |
| Tamura, K | 1 |
| Umemura, S | 1 |
| Nagasu, H | 1 |
| Satoh, M | 1 |
| Yorimitsu, D | 1 |
| Tomita, N | 1 |
| Sasaki, T | 1 |
| Kashihara, N | 1 |
| Choi, JN | 1 |
| Lee, JS | 1 |
| Shin, JI | 1 |
| Fanelli, C | 1 |
| Fernandes, BH | 1 |
| Machado, FG | 1 |
| Okabe, C | 1 |
| Malheiros, DM | 2 |
| Fujihara, CK | 2 |
| Zatz, R | 2 |
| Nguyen, TQ | 1 |
| Hemmelder, MH | 1 |
| Goldschmeding, R | 1 |
| Dussol, B | 1 |
| Moussi-Frances, J | 1 |
| Morange, S | 1 |
| Somma-Delpero, C | 1 |
| Mundler, O | 1 |
| Berland, Y | 1 |
| Izzo, JL | 1 |
| Hayek, M | 1 |
| Srinivasan, A | 1 |
| BUZZI, RM | 1 |
| SAMMARTINO, F | 1 |
| MAS, FR | 1 |
| LA ROSA, C | 1 |
| GELFAND, ML | 1 |
| WINTER, M | 1 |
| WALTNER, K | 1 |
| SINGH, D | 1 |
| PANDEY, GN | 1 |
| BRETTELL, HR | 1 |
| SMITH, JG | 1 |
| AIKAWA, JK | 1 |
| DUNLOP, D | 1 |
| PEDERSEN, J | 1 |
| LINDENEG, O | 1 |
| FISCHER, S | 1 |
| BAGROS, P | 1 |
| MIHAILESCU, VV | 1 |
| CLEJ, V | 1 |
| ENESCU, R | 1 |
| SBENGHE, S | 1 |
| MERZON, AK | 1 |
| KASIANOVA, TN | 1 |
| ANICHINI, M | 1 |
| GARGANO, N | 1 |
| BARTORELLI, C | 1 |
| KJELLBO, H | 1 |
| STAKEBERG, H | 1 |
| MELLGREN, J | 1 |
| Ogata, S | 1 |
| Sharyo, S | 1 |
| Hinman, DJ | 1 |
| Manabe, S | 1 |
| Lock, BJ | 1 |
| Eggert, M | 1 |
| Cooper, JA | 1 |
| Weinstein, AM | 2 |
| Zhou, X | 1 |
| Matavelli, LC | 1 |
| Ono, H | 1 |
| Frohlich, ED | 1 |
| Suzuki, M | 1 |
| Aso, T | 1 |
| Sato, T | 1 |
| Michimata, M | 1 |
| Kazama, I | 1 |
| Saiki, H | 1 |
| Hatano, R | 1 |
| Ejima, Y | 1 |
| Miyama, N | 1 |
| Sato, A | 1 |
| Matsubara, M | 1 |
| Minutolo, R | 1 |
| De Nicola, L | 1 |
| Zamboli, P | 1 |
| Chiodini, P | 1 |
| Signoriello, G | 1 |
| Toderico, C | 1 |
| Arfè, G | 1 |
| Boschi, G | 1 |
| Brancati, C | 1 |
| Iaccarino, P | 1 |
| Conte, G | 1 |
| Shord, SS | 1 |
| Thompson, DM | 1 |
| Krempl, GA | 1 |
| Hanigan, MH | 1 |
| Xie, HH | 1 |
| Shen, FM | 1 |
| Zhang, XF | 1 |
| Jiang, YY | 1 |
| Su, DF | 1 |
| Tschöpe, C | 1 |
| Tschöpe, R | 1 |
| Unger, T | 1 |
| Aleksandrowicz, E | 1 |
| Lysiak-Szydlowska, W | 1 |
| Bufalari, A | 1 |
| Meloni, G | 1 |
| McFate Smith, W | 1 |
| Kulaga, SF | 1 |
| Moncloa, F | 1 |
| Pingeon, R | 1 |
| Walker, JF | 1 |
| Kher, A | 1 |
| Fillastre, JP | 1 |
| Fourtillan, JB | 1 |
| Lefebvre, MA | 1 |
| Ingrand, I | 1 |
| Monnens, L | 1 |
| Jonkman, A | 1 |
| Thomas, C | 1 |
| Niemeyer, C | 1 |
| Hasenfuss, G | 1 |
| Wais, U | 1 |
| Knauf, H | 1 |
| Schäfer-Korting, M | 1 |
| Mutschler, E | 1 |
| Demers, RG | 1 |
| Rivenbark, JF | 1 |
| Emmerson, BT | 1 |
| Renshaw, PJ | 1 |
| Ravenscroft, PJ | 1 |
| Denham, I | 1 |
| Schey, S | 1 |
| Zerwekh, JE | 1 |
| Sakhaee, K | 3 |
| Pak, CY | 4 |
| Hiatt, RA | 1 |
| Tolan, K | 1 |
| Quesenberry, CP | 1 |
| Hersh, AD | 1 |
| Kelly, JG | 1 |
| Laher, MS | 2 |
| Carmody, M | 1 |
| Doyle, GD | 1 |
| Wu, MS | 1 |
| Hong, JJ | 1 |
| Lin, JL | 1 |
| Yang, CW | 1 |
| Chien, HC | 1 |
| Ruggenenti, P | 1 |
| Brenner, BM | 2 |
| Burgess, HK | 1 |
| Jayawardene, SA | 1 |
| Velasco, N | 1 |
| Bald, M | 1 |
| Vester, U | 1 |
| Wingen, AM | 1 |
| Broadus, AE | 1 |
| Dominguez, M | 1 |
| Bartter, FC | 1 |
| Beg, MA | 1 |
| Ragland, R | 1 |
| Sztriha, L | 1 |
| Beviz, J | 1 |
| Vogin, EE | 1 |
| Mulkerrins, E | 1 |
| Hosie, J | 1 |
| Connell, PA | 1 |
| Smith, RP | 1 |
| Swaisland, AJ | 1 |
| de Leeuw, PW | 1 |
| Simeonov, S | 1 |
| Bucher, JR | 1 |
| Huff, J | 1 |
| Haseman, JK | 1 |
| Eustis, SL | 1 |
| Elwell, MR | 1 |
| Davis, WE | 1 |
| Meierhenry, EF | 1 |
| Rodríguez-Soriano, J | 1 |
| Vallo, A | 1 |
| Domínguez, MJ | 1 |
| Reams, GP | 1 |
| Bauer, JH | 1 |
| Anderson, S | 1 |
| Rennke, HG | 1 |
| Thind, GS | 1 |
| Rascher, W | 1 |
| Rosendahl, W | 1 |
| Henrichs, IA | 1 |
| Maier, R | 1 |
| Seyberth, HW | 1 |
| Preminger, GM | 1 |
| Lijinsky, W | 1 |
| Reuber, MD | 1 |
| Hande, KR | 1 |
| Moss, AH | 1 |
| Nicar, MJ | 2 |
| Glass, K | 1 |
| Brater, DC | 1 |
| Groover, ME | 1 |
| Fulghum, JE | 1 |
| Simpson, WG | 1 |
| Godard, C | 1 |
| Mégevand, A | 1 |
| de Sousa, RC | 1 |
| Muller, AF | 1 |
| Coppi, G | 1 |
| Bonardi, G | 1 |
| Gaetani, M | 1 |
| Imhof, PR | 1 |
| Hushak, J | 1 |
| Schumann, G | 1 |
| Dukor, P | 1 |
| Wagner, J | 1 |
| Keller, HM | 1 |
| Spanos, PK | 1 |
| Simmons, RL | 1 |
| Kjellstrand, CM | 1 |
| Buselmeier, TJ | 1 |
| Najarian, JS | 1 |
| Jones, J | 1 |
| Lage, AL | 1 |
| Delevett, AF | 1 |
| Recalde, M | 1 |
| Wiggelinkhuizen, J | 1 |
| Retief, PJ | 1 |
| Wolff, B | 1 |
| Fisher, RM | 1 |
| Cremin, BJ | 1 |
| Nigrovic, V | 1 |
| Koechel, DA | 1 |
| Cafruny, EJ | 1 |
| Green, RA | 1 |
| Farrow, CS | 1 |
| Morishima, A | 1 |
| Morio, K | 1 |
| Gastaldi, L | 1 |
| Buccianti, G | 1 |
| Rizzato, G | 1 |
| Marazzini, L | 1 |
| Eto, M | 1 |
| Lavicka, J | 1 |
| Chaloupková, E | 1 |
| Amerio, A | 1 |
| Urakabe, S | 1 |
| Orita, Y | 1 |
| Furukawa, T | 1 |
| Abe, H | 1 |
| Tretenhahn, W | 1 |
| Walizadeh, R | 1 |
| Mioli, V | 1 |
| Zucchelli, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| DD-study: Diet or Diuretics for Salt-sensitivity in Chronic Kidney Disease[NCT02875886] | Phase 4 | 28 participants (Actual) | Interventional | 2016-09-30 | Completed | ||
| Chlortalidone and Bumetanide in Advanced Chronic Kidney Disease: HEBE-CKD Trial[NCT03923933] | Phase 2 | 34 participants (Actual) | Interventional | 2019-06-18 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | mmHg (Mean) |
|---|---|
| Placebo | -3.4 |
| Treatment Grup | -13.5 |
Decrease in extracellular water measured by bioelectrical impedance analysis (NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | litres (Mean) |
|---|---|
| Placebo | -0.15 |
| Treatment Grup | 2.55 |
Decrease in extracellular water / total body water ratio measured by bioelectrical impedance analysis (NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | percentage of ECW/TBW (Mean) |
|---|---|
| Placebo | -0.24 |
| Treatment Grup | -2.92 |
decrease in blood pressure compared wit baseline measure (mmhg) (NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | mmHg (Mean) |
|---|---|
| Placebo | -5.4 |
| Treatment Grup | -18.1 |
(NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | mmHg (Mean) |
|---|---|
| Placebo | -10 |
| Treatment Grup | -26.1 |
Increase in the fractional excretion of sodium compared with the baseline measure (NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | percentage of sodium excreted (Mean) |
|---|---|
| Placebo | -0.348 |
| Treatment Grup | 0.598 |
Measured by bioelectrical impedance analysis, compared to the initial measurement (NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | litres (Mean) |
|---|---|
| Placebo | -0.075 |
| Treatment Grup | -4.36 |
5 reviews available for hydrochlorothiazide and Kidney Diseases
| Article | Year |
|---|---|
Efficacy of Zofenopril Alone or in Combination with Hydrochlorothiazide in Patients with Kidney Dysfunction.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Diuretics; Drug Therapy, Combination; | 2019 |
Zofenopril plus hydrochlorothiazide fixed combination in the treatment of hypertension and associated clinical conditions.
Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Diuretics; Drug Therapy, Combination; Humans; H | 2009 |
[MECHANISM OF ACTION AND CLINICAL USE OF DIURETICS].
Topics: Bendroflumethiazide; Benzothiadiazines; Chlorothiazide; Chlorthalidone; Diuretics; Hydrochlorothiazi | 1963 |
Infiltrative lung disease due to noncytotoxic agents.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Aspirin; Humans; Hydrochlorothiazide; | 2004 |
Renin and hypertension: a review article.
Topics: Aldosterone; Humans; Hydrochlorothiazide; Hypertension; Juxtaglomerular Apparatus; Kidney Diseases; | 1973 |
18 trials available for hydrochlorothiazide and Kidney Diseases
| Article | Year |
|---|---|
Anti-hypertensive strategies in patients with MEtabolic parameters, DIabetes mellitus and/or NephropAthy (the M E D I N A study).
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Block | 2014 |
Acetazolamide and Hydrochlorothiazide Followed by Furosemide Versus Furosemide and Hydrochlorothiazide Followed by Furosemide for the Treatment of Adults With Nephrotic Edema: A Randomized Trial.
Topics: Acetazolamide; Adult; Diuretics; Double-Blind Method; Drug Therapy, Combination; Edema; Female; Furo | 2017 |
Effect of renin-angiotensin-aldosterone system inhibition, dietary sodium restriction, and/or diuretics on urinary kidney injury molecule 1 excretion in nondiabetic proteinuric kidney disease: a post hoc analysis of a randomized controlled trial.
Topics: Acetylglucosaminidase; Adult; Aged; Antihypertensive Agents; Biomarkers; Chronic Disease; Combined M | 2009 |
Spironolactone attenuates oxidative stress in patients with chronic kidney disease.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antioxidan | 2008 |
Antiproteinuric therapy decreases LDL-cholesterol as well as HDL-cholesterol in non-diabetic proteinuric patients: relationships with cholesteryl ester transfer protein mass and adiponectin.
Topics: Adiponectin; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Cholesterol Ester Transfer Protei | 2009 |
Renoprotect and blood pressure lowering effect of low-dose hydrochlorothiazide added to intensive renin-angiotensin inhibition in hypertensive patients with chronic kidney disease.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihyperte | 2009 |
Antiproteinuric and blood pressure-lowering effects of a fixed-dose combination of losartan and hydrochlorothiazide in hypertensive patients with stage 3 chronic kidney disease.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Chronic Disease; Creatinine; Dose-Response Relationsh | 2009 |
Effects of antiproteinuric intervention on elevated connective tissue growth factor (CTGF/CCN-2) plasma and urine levels in nondiabetic nephropathy.
Topics: Angiotensin II Type 1 Receptor Blockers; Biomarkers; Chronic Disease; Combined Modality Therapy; Con | 2011 |
A pilot study comparing furosemide and hydrochlorothiazide in patients with hypertension and stage 4 or 5 chronic kidney disease.
Topics: Aged; Anthropology; Biological Availability; Blood Pressure; Chronic Disease; Diet Records; Diuretic | 2012 |
Triple pharmacological blockade of the renin-angiotensin-aldosterone system in nondiabetic CKD: an open-label crossover randomized controlled trial.
Topics: Acetylglucosaminidase; Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme | 2008 |
Overall tolerance and safety of enalapril.
Topics: Captopril; Clinical Trials as Topic; Creatinine; Dose-Response Relationship, Drug; Drug Therapy, Com | 1984 |
Ticrynafen and hydrochlorothiazide. A comparison in hypertensive patients with renal impairment.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Glycolates; Huma | 1982 |
Effect of hydrochlorothiazide on the pharmacokinetics of enalapril in hypertensive patients with varying renal function.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Cross-Over Studies; Diuretics; Drug Therapy, | 1996 |
Safety of tienilic acid.
Topics: Clinical Trials as Topic; Glycolates; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Kidn | 1979 |
The effects of age and renal impairment on the pharmacokinetics of co-administered lisinopril and hydrochlorothiazide.
Topics: Adult; Aged; Aged, 80 and over; Aging; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Dru | 1991 |
Renal function in the elderly: results from the European Working Party on High Blood Pressure in the Elderly trial.
Topics: Aged; Creatinine; Double-Blind Method; Drug Therapy, Combination; Europe; Female; Humans; Hydrochlor | 1991 |
Enalapril versus triple-drug therapy in the treatment of renovascular hypertension.
Topics: Angiotensin II; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Meth | 1985 |
Excretion of urinary casts after the administration of diuretics.
Topics: Chemical Precipitation; Chlorthalidone; Clinical Trials as Topic; Diuresis; Diuretics; Ethacrynic Ac | 1972 |
77 other studies available for hydrochlorothiazide and Kidney Diseases
| Article | Year |
|---|---|
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological | 2010 |
Diuretic and Renal Protective Effect of Kaempferol 3-
Topics: Animals; Antioxidants; Bauhinia; Calcium; Chlorides; Cyclooxygenase Inhibitors; Diuretics; Hypertens | 2020 |
Multiple Mechanisms are Involved in Salt-Sensitive Hypertension-Induced Renal Injury and Interstitial Fibrosis.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Capillaries; Fibrosis; Hydrochlorothiazide; Hypert | 2017 |
Kidney injury molecule 1: in search of biomarkers of chronic tubulointerstitial damage and disease progression.
Topics: Animals; Antihypertensive Agents; Biomarkers; Chronic Disease; Disease Models, Animal; Disease Progr | 2009 |
RAAS blockade in combination with diuretic therapy increases urine excretion, which in turn increases drinking and thus reduces erythropoietin and proteinuria.
Topics: Chronic Disease; Diuretics; Drinking Behavior; Drug Therapy, Combination; Erythropoietin; Hemodiluti | 2010 |
Reversible effects of diuretics added to renin-angiotensin-aldosterone system blockade: impact on interpretation of long-term kidney function outcome.
Topics: Amlodipine; Chronic Disease; Data Interpretation, Statistical; Diuretics; Humans; Hydrochlorothiazid | 2010 |
[Effects of combination therapy with losartan/hydrochlorothiazide on the relationships between base blood pressure, autonomic function, and health-related QOL].
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Autonomic Nervous System; Bl | 2010 |
Comparison of combination therapy of olmesartan plus azelnidipine or hydrochlorothiazide on renal and vascular damage in SHR/NDmcr-cp rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Azetidinecarboxylic Acid; | 2011 |
Low-dose thiazide diuretics in children with idiopathic renal hypercalciuria.
Topics: Child; Diuretics; Female; Hematuria; Humans; Hydrochlorothiazide; Hypercalciuria; Kidney Diseases; M | 2011 |
Effects of losartan, in monotherapy or in association with hydrochlorothiazide, in chronic nephropathy resulting from losartan treatment during lactation.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Blood Pressure; | 2011 |
Value of combined thiazide-loop diuretic therapy in chronic kidney disease: heart failure and renin-angiotensin-aldosterone blockade.
Topics: Blood Pressure; Female; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Kidney Diseases; Male | 2012 |
Acute lymphoblastic leukemia presenting with lactic acidosis and renal tubular dysfunction.
Topics: Acidosis, Lactic; Antineoplastic Combined Chemotherapy Protocols; Calcium; Child; Diuretics; Humans; | 2003 |
[Hydrochlorothiazide in clinical practice].
Topics: Chlorothiazide; Coronary Disease; Diuretics; Hydrochlorothiazide; Hypertension; Kidney Diseases; Liv | 1960 |
Renal colic associated with chlorothiazide and hydrochlorothiazide therapy.
Topics: Chlorothiazide; Hydrochlorothiazide; Kidney; Kidney Diseases; Renal Colic | 1961 |
[Experiences with the use of chlorothiazide and hydrochlorothiazide in kidney diseases].
Topics: Chlorothiazide; Hydrochlorothiazide; Kidney Diseases | 1959 |
Clinical evaluation of hydrochlorothiazide in renal oedema.
Topics: Chlorothiazide; Edema; Edetic Acid; Humans; Hydrochlorothiazide; Kidney; Kidney Diseases | 1962 |
S35-LABELED BENDROFLUMETHIAZIDE IN HUMAN BEINGS: CLINICAL STUDIES.
Topics: Adolescent; Bendroflumethiazide; Chlorothiazide; Geriatrics; Heart Failure; Humans; Hydrochlorothiaz | 1964 |
[ACUTE MALIGNANT HYPERTENSION WITH SECONDARY ALDOSTERONISM. A CASE IN A 31-YEAR-OLD MAN WITH CONGENITAL UNILATERAL RENAL HYPOPLASIA].
Topics: Alkalosis; Antihypertensive Agents; Blood Chemical Analysis; Congenital Abnormalities; Guanethidine; | 1964 |
[THE TREATMENT OF EDEMA WITH SULFONAMIDE DIURETICS].
Topics: Acetazolamide; Acidosis; Benzothiadiazines; Chlorothiazide; Chlorthalidone; Dehydration; Diuretics; | 1964 |
[CONSIDERATIONS ON THE RENAL SIDE-EFFECTS DURING TREATMENT OF ARTERIAL HYPERTENSION].
Topics: Bretylium Compounds; Chlorothiazide; Guanethidine; Hydralazine; Hydrochlorothiazide; Hypertension; K | 1964 |
[CLINICAL AND BIOCHEMICAL EVALUATION OF THE DIURETIC ACTION OF HYPOTHIAZIDE].
Topics: Biomedical Research; Blood; Chlorine; Chlorothiazide; Diuretics; Drug Therapy; Edema; Heart Failure; | 1964 |
[SECONDARY ASPECIFIC EFFECTS OF BENZOTHIAZINIC DIURETICS].
Topics: Agranulocytosis; Amylases; Blood Glucose; Chlorothiazide; Diabetes Mellitus; Diuretics; Drug Eruptio | 1964 |
POSSIBLY THIAZIDE-INDUCED RENAL NECROTISING VASCULITIS.
Topics: Chlorothiazide; Hydrochlorothiazide; Inflammation; Kidney Diseases; Necrosis; Pathology; Skin Diseas | 1965 |
Renal effects of 26-week administration of olmesartan medoxomil/hydrochlorothiazide in rats.
Topics: Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blo | 2004 |
A mathematical model of rat distal convoluted tubule. II. Potassium secretion along the connecting segment.
Topics: Acid-Base Equilibrium; Algorithms; Alkalosis; Animals; Cell Membrane Permeability; Diuretics; Electr | 2005 |
A mathematical model of rat distal convoluted tubule. I. Cotransporter function in early DCT.
Topics: Acid-Base Equilibrium; Algorithms; Alkalosis; Animals; Bicarbonates; Cell Membrane Permeability; Cyt | 2005 |
Superiority of combination of thiazide with angiotensin-converting enzyme inhibitor or AT1-receptor blocker over thiazide alone on renoprotection in L-NAME/SHR.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pr | 2005 |
A case of gain-of-function mutation in calcium-sensing receptor: supplemental hydration is required for renal protection.
Topics: Administration, Oral; Calcium; Child; DNA; DNA Mutational Analysis; Extracellular Fluid; Female; Fol | 2005 |
Management of hypertension in patients with CKD: differences between primary and tertiary care settings.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzy | 2005 |
Effect of concurrent medications on cisplatin-induced nephrotoxicity in patients with head and neck cancer.
Topics: Albuterol; Antihypertensive Agents; Antineoplastic Combined Chemotherapy Protocols; Atenolol; Cispla | 2006 |
Blood pressure variability, baroreflex sensitivity and organ damage in spontaneously hypertensive rats treated with various antihypertensive drugs.
Topics: Animals; Antihypertensive Agents; Aorta; Atenolol; Baroreflex; Biphenyl Compounds; Blood Pressure; C | 2006 |
[Microalbuminuria in patients with hypertension and cardiovascular comorbidity, REAL observational study of treatment with Irbesartan/HCTZ].
Topics: Adult; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compo | 2006 |
Losartan-hydrochlorothiazide association promotes lasting blood pressure normalization and completely arrests long-term renal injury in the 5/6 ablation model.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Diuretics | 2007 |
[The behavior of uricemia during treatment with spironolactone and with other diuretics].
Topics: Acetazolamide; Adolescent; Adult; Aged; Chlorthalidone; Clopamide; Diuretics; Ethacrynic Acid; Femal | 1967 |
Pharmacokinetics of a fixed combination of sotalol and hydrochlorothiazide in hypertensive patients with moderate renal insufficiency.
Topics: Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Kidney Diseases; Kinetics; Sotalol | 1984 |
Response to indomethacin and hydrochlorothiazide in nephrogenic diabetes insipidus.
Topics: Child; Diabetes Insipidus; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Indomethacin; Inf | 1984 |
Pharmacokinetics of hydrochlorothiazide in relation to renal function.
Topics: Adult; Aged; Female; Humans; Hydrochlorothiazide; Kidney; Kidney Diseases; Kinetics; Male; Metabolic | 1983 |
Lithium intoxication and its clinical management.
Topics: Antihypertensive Agents; Drug Combinations; Drug Interactions; Humans; Hydrochlorothiazide; Kidney D | 1982 |
Utility and limitation of calciuric response to oral calcium load as a measure of intestinal calcium absorption: comparison with isotopic fractional calcium absorption.
Topics: Administration, Oral; Calcium; Calcium Radioisotopes; Feces; Humans; Hydrochlorothiazide; Intestinal | 1981 |
Renal cell carcinoma and thiazide use: a historical, case-control study (California, USA).
Topics: Body Mass Index; California; Carcinoma, Renal Cell; Case-Control Studies; Diuretics; Dose-Response R | 1994 |
Multiple tubular dysfunction induced by mixed Chinese herbal medicines containing cadmium.
Topics: Adult; Cadmium; Drugs, Chinese Herbal; Female; Furosemide; Humans; Hydrochlorothiazide; Kidney Disea | 1996 |
Remission achieved in chronic nephropathy by a multidrug approach targeted at urinary protein excretion.
Topics: Adult; Algorithms; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Diure | 2001 |
Dent's disease: can we slow its progression?
Topics: Adolescent; Calcium; Disease Progression; Female; Humans; Hydrochlorothiazide; Hypophosphatemia; Kid | 2001 |
Dent's disease.
Topics: Calcium; Diuretics; Humans; Hydrochlorothiazide; Hypokalemia; Kidney Diseases; Kidney Failure, Chron | 2002 |
Pathophysiological studies in idiopathic hypercalciuria: use of an oral calcium tolerance test to characterize distinctive hypercalciuric subgroups.
Topics: Adult; Calcium; Cyclic AMP; Female; Humans; Hydrochlorothiazide; Hyperparathyroidism; Intestinal Abs | 1978 |
[Idiopathic hypercalcaemia. The effect of hypercalcaemia on renal function (author's transl)].
Topics: Humans; Hydrochlorothiazide; Hypercalcemia; Infant; Kidney Diseases; Male; Nephrocalcinosis; Prednis | 1979 |
Renal function testing: differentiation between a nephrotoxic agent and diuretic drugs.
Topics: Acetazolamide; Animals; Chlorothiazide; Diuretics; Dogs; Ethacrynic Acid; Female; Hydrochlorothiazid | 1977 |
Therapeutic management of bone and renal forms of hyperparathyroidism. Results of surgical and conservative treatment.
Topics: Bone Diseases; Humans; Hydrochlorothiazide; Hyperparathyroidism; Kidney Diseases | 1990 |
Toxicology and carcinogenicity studies of diuretics in F344 rats and B6C3F1 mice. 1. Hydrochlorothiazide.
Topics: Adenofibroma; Animals; Body Weight; Carcinogens; Chronic Kidney Disease-Mineral and Bone Disorder; D | 1990 |
"Chloride-shunt" syndrome: an overlooked cause of renal hypercalciuria.
Topics: Atrial Natriuretic Factor; Calcium; Chlorides; Humans; Hydrochlorothiazide; Infant; Kidney; Kidney D | 1989 |
Therapeutic advantage of converting enzyme inhibitors in arresting progressive renal disease associated with systemic hypertension in the rat.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Enalapril; Glomerular Filtration Rate; Hydralazin | 1986 |
Renal insufficiency during angiotensin-converting enzyme inhibitor therapy in hypertensive patients with no renal artery stenosis.
Topics: Acute Kidney Injury; Captopril; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Hypert | 1985 |
Congenital nephrogenic diabetes insipidus-vasopressin and prostaglandins in response to treatment with hydrochlorothiazide and indomethacin.
Topics: Child; Child, Preschool; Diabetes Insipidus; Humans; Hydrochlorothiazide; Indomethacin; Infant; Kidn | 1987 |
Eventual attenuation of hypocalciuric response to hydrochlorothiazide in absorptive hypercalciuria.
Topics: Adult; Aged; Calcium; Calcium Metabolism Disorders; Calcium, Dietary; Female; Humans; Hydrochlorothi | 1987 |
Pathologic effects of chronic administration of hydrochlorothiazide, with and without sodium nitrite, to F344 rats.
Topics: Animals; Arteritis; Carcinogens; Female; Heart Diseases; Hydrochlorothiazide; Kidney Diseases; Male; | 1987 |
Evaluation of a thiazide-allopurinol drug interaction.
Topics: Adolescent; Adult; Allopurinol; Diuretics; Drug Evaluation; Drug Interactions; Half-Life; Humans; Hy | 1986 |
Renal colic, arthralgia in a hypercalcemic man.
Topics: Adult; Calcium; Colic; Humans; Hydrochlorothiazide; Hypercalcemia; Hyperparathyroidism; Joint Diseas | 1985 |
Postmenopausal osteoporosis as a manifestation of renal hypercalciuria with secondary hyperparathyroidism.
Topics: Aged; Bone and Bones; Calcium; Female; Humans; Hydrochlorothiazide; Hyperparathyroidism, Secondary; | 1985 |
Exaggerated natriuretic and calciuric responses to hydrochlorothiazide in renal hypercalciuria but not in absorptive hypercalciuria.
Topics: Absorption; Adolescent; Adult; Aged; Calcium; Cations; Diagnosis, Differential; Humans; Hydrochlorot | 1985 |
Arterial hypertension--northwest Florida public health survey. II. Diagnosis and treatment.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Urea Nitrogen; Chlorothiazide; Diuretics | 1974 |
[Study of aldosterone metabolism in a case of congenital nephrogenic diabetes insipidus].
Topics: Aldosterone; Angiotensin II; Diabetes Insipidus; Diet, Sodium-Restricted; Humans; Hydrochlorothiazid | 1968 |
Experimental gastric ulcers and uropepsinogen excretion in the rat.
Topics: Animals; Atropine; Carbon Tetrachloride; Endopeptidases; Enzyme Precursors; Female; Hydrochlorothiaz | 1971 |
Kidney transplantation from living related donors with multiple vessels. A problem revisited.
Topics: Adolescent; Adult; Blood Pressure; Cadaver; Child; Child, Preschool; Creatinine; Female; Follow-Up S | 1973 |
Nephrogenic diabetes insipidus in a dog.
Topics: Animals; Blood Proteins; Diabetes Insipidus; Diagnosis, Differential; Dog Diseases; Dogs; Hydrochlor | 1973 |
Diuretic-induced renal colic.
Topics: Adult; Colic; Edema; Female; Humans; Hydrochlorothiazide; Kidney Diseases; Triamterene | 1973 |
Nephrogenic diabetes insipidus and obstructive uropathy.
Topics: Adolescent; Diabetes Insipidus; Diuretics; Female; Humans; Hydrochlorothiazide; Hydronephrosis; Hype | 1973 |
The effects of maleic acid and uranyl on mercurial diuresis in dogs.
Topics: Acetates; Acetazolamide; Animals; Chlorides; Diuresis; Dogs; Ethacrynic Acid; Furosemide; Hydrochlor | 1973 |
Diabetes insipidus in a cat.
Topics: Animals; Cat Diseases; Cats; Chronic Disease; Dehydration; Diabetes Insipidus; Hydrochlorothiazide; | 1974 |
[Case of congenital nephrogenic diabetes insipidus in an infant].
Topics: Air Conditioning; Diabetes Insipidus; Humans; Hydrochlorothiazide; Infant; Kidney Diseases; Male; Pr | 1972 |
[Some aspects of renal metabolism of citric acid].
Topics: Adult; Age Factors; Aged; Chlorthalidone; Citrates; Heart Failure; Humans; Hydrochlorothiazide; Hype | 1970 |
[Plasma renin activity in hypertensive and non-hypertensive patients and its clinical significance].
Topics: Addison Disease; Adolescent; Adult; Aged; Aortic Diseases; Biological Assay; Blood Pressure; Blood U | 1970 |
[Hyperuricemia in internal diseases].
Topics: Anemia; Cardiovascular Diseases; Gout; Hematologic Diseases; Humans; Hydrochlorothiazide; Kidney Dis | 1969 |
[Study on the therapeutic effect of thiazide and triamterene combinations].
Topics: Edema; Heart Diseases; Humans; Hydrochlorothiazide; Kidney Diseases; Liver Cirrhosis; Lymphatic Dise | 1963 |
Analysis of urea excretion with special reference to the influence of abrupt change in urine flow.
Topics: Adult; Animals; Chlorides; Chlorthalidone; Diabetes Insipidus; Diuresis; Female; Humans; Hydrochloro | 1965 |
[The treatment of hypertension].
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Arteriosclerosis; Child; Child, Preschool; Coronar | 1966 |
[On 2 cases of renal diabetes insipidus].
Topics: Child, Preschool; Diabetes Insipidus; Humans; Hydrochlorothiazide; Infant; Kidney Diseases; Kidney T | 1966 |
[The clinical use of an association of hydrochlorothiazide and triamterene in nephrotic syndromes].
Topics: Adolescent; Adult; Aged; Amyloidosis; Child; Diabetic Nephropathies; Diuresis; Electrolytes; Female; | 1966 |