hydrochlorothiazide has been researched along with Inflammation in 12 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study aimed to evaluate whether exercise training could contribute to a better modulation of the neurohumoral mechanisms linked to the pathophysiology of arterial hypertension (AH) in postmenopausal hypertensive rats treated with hydrochlorothiazide (HCTZ)." | 8.31 | Concurrent exercise training induces additional benefits to hydrochlorothiazide: Evidence for an improvement of autonomic control and oxidative stress in a model of hypertension and postmenopause. ( Bernardes, N; da Silva Dias, D; De Angelis, K; Ferreira, MJ; Irigoyen, MC; Santos Ferreira Silva, MPD, 2023) |
| " To assess the effects of photosensitizing drugs voriconazole and hydrochlorothiazide (HCTZ) on the enhancement of UV-induced inflammatory responses and UV-induced tumorigenesis, we utilized Xpa-knockout mice, which is DNA repair-deficient and more susceptible to UV-induced inflammation and tumor development than wild-type mice." | 7.88 | Inflammation Due to Voriconazole-induced Photosensitivity Enhanced Skin Phototumorigenesis in Xpa-knockout Mice. ( Hosaka, C; Kunisada, M; Nishigori, C; Takemori, C; Yamano, N, 2018) |
| "We hypothesized that compared with hydrochlorothiazide (HCTZ), the renin inhibitor aliskiren (ALISK) or amlodipine (AMLO) and their combination reduce albuminuria via reduction in renal inflammation, independent of blood pressure (BP) changes." | 7.78 | Combined aliskiren and amlodipine reduce albuminuria via reduction in renal inflammation in diabetic rats. ( Huang, J; Matavelli, LC; Siragy, HM, 2012) |
| "Baseline low-grade inflammation in patients with hypertension was associated with a poor ambulatory BP response, especially with losartan/HCTZ treatment." | 5.17 | Low-grade inflammation and ambulatory blood pressure response to antihypertensive treatment: the ALPHABET study. ( Eguchi, K; Fukutomi, M; Hoshide, S; Kario, K; Watanabe, T, 2013) |
| "This study aimed to evaluate whether exercise training could contribute to a better modulation of the neurohumoral mechanisms linked to the pathophysiology of arterial hypertension (AH) in postmenopausal hypertensive rats treated with hydrochlorothiazide (HCTZ)." | 4.31 | Concurrent exercise training induces additional benefits to hydrochlorothiazide: Evidence for an improvement of autonomic control and oxidative stress in a model of hypertension and postmenopause. ( Bernardes, N; da Silva Dias, D; De Angelis, K; Ferreira, MJ; Irigoyen, MC; Santos Ferreira Silva, MPD, 2023) |
| " To assess the effects of photosensitizing drugs voriconazole and hydrochlorothiazide (HCTZ) on the enhancement of UV-induced inflammatory responses and UV-induced tumorigenesis, we utilized Xpa-knockout mice, which is DNA repair-deficient and more susceptible to UV-induced inflammation and tumor development than wild-type mice." | 3.88 | Inflammation Due to Voriconazole-induced Photosensitivity Enhanced Skin Phototumorigenesis in Xpa-knockout Mice. ( Hosaka, C; Kunisada, M; Nishigori, C; Takemori, C; Yamano, N, 2018) |
| "We hypothesized that compared with hydrochlorothiazide (HCTZ), the renin inhibitor aliskiren (ALISK) or amlodipine (AMLO) and their combination reduce albuminuria via reduction in renal inflammation, independent of blood pressure (BP) changes." | 3.78 | Combined aliskiren and amlodipine reduce albuminuria via reduction in renal inflammation in diabetic rats. ( Huang, J; Matavelli, LC; Siragy, HM, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Ferreira, MJ | 1 |
| Santos Ferreira Silva, MPD | 1 |
| da Silva Dias, D | 1 |
| Bernardes, N | 1 |
| Irigoyen, MC | 1 |
| De Angelis, K | 1 |
| Kunisada, M | 1 |
| Yamano, N | 1 |
| Hosaka, C | 1 |
| Takemori, C | 1 |
| Nishigori, C | 1 |
| Fukutomi, M | 1 |
| Hoshide, S | 1 |
| Eguchi, K | 1 |
| Watanabe, T | 1 |
| Kario, K | 1 |
| Ma, F | 1 |
| Lin, F | 1 |
| Chen, C | 1 |
| Cheng, J | 1 |
| Zeldin, DC | 1 |
| Wang, Y | 1 |
| Wang, DW | 1 |
| Matavelli, LC | 1 |
| Huang, J | 1 |
| Siragy, HM | 1 |
| Villa, L | 1 |
| Boor, P | 1 |
| Konieczny, A | 1 |
| Kunter, U | 1 |
| van Roeyen, CR | 1 |
| Denecke, B | 1 |
| Gan, L | 1 |
| Neusser, MA | 1 |
| Cohen, CD | 1 |
| Eitner, F | 1 |
| Scholl, T | 1 |
| Ostendorf, T | 1 |
| Floege, J | 1 |
| KJELLBO, H | 1 |
| STAKEBERG, H | 1 |
| MELLGREN, J | 1 |
| Schram, MT | 1 |
| van Ittersum, FJ | 1 |
| Spoelstra-de Man, A | 1 |
| van Dijk, RA | 1 |
| Schalkwijk, CG | 1 |
| Ijzerman, RG | 1 |
| Twisk, JW | 1 |
| Stehouwer, CD | 1 |
| Ridker, PM | 1 |
| Danielson, E | 1 |
| Rifai, N | 1 |
| Glynn, RJ | 1 |
| Rahman, ST | 1 |
| Lauten, WB | 1 |
| Khan, QA | 1 |
| Navalkar, S | 1 |
| Parthasarathy, S | 1 |
| Khan, BV | 1 |
| Saito, T | 1 |
| Yoshida, S | 1 |
| Nakao, K | 1 |
| Takanashi, R | 1 |
3 trials available for hydrochlorothiazide and Inflammation
| Article | Year |
|---|---|
Low-grade inflammation and ambulatory blood pressure response to antihypertensive treatment: the ALPHABET study.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dose-Res | 2013 |
Aggressive antihypertensive therapy based on hydrochlorothiazide, candesartan or lisinopril as initial choice in hypertensive type II diabetic individuals: effects on albumin excretion, endothelial function and inflammation in a double-blind, randomized c
Topics: Adult; Aged; Albuminuria; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Diabetes Mell | 2005 |
Valsartan, blood pressure reduction, and C-reactive protein: primary report of the Val-MARC trial.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Pressure; | 2006 |
9 other studies available for hydrochlorothiazide and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Concurrent exercise training induces additional benefits to hydrochlorothiazide: Evidence for an improvement of autonomic control and oxidative stress in a model of hypertension and postmenopause.
Topics: Animals; Baroreflex; Blood Pressure; Female; Heart Rate; Hexamethonium; Hydrochlorothiazide; Hyperte | 2023 |
Inflammation Due to Voriconazole-induced Photosensitivity Enhanced Skin Phototumorigenesis in Xpa-knockout Mice.
Topics: Animals; Antifungal Agents; Antihypertensive Agents; Cocarcinogenesis; Cytokines; Hydrochlorothiazid | 2018 |
Indapamide lowers blood pressure by increasing production of epoxyeicosatrienoic acids in the kidney.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; | 2013 |
Combined aliskiren and amlodipine reduce albuminuria via reduction in renal inflammation in diabetic rats.
Topics: Albuminuria; Amides; Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus | 2012 |
Late angiotensin II receptor blockade in progressive rat mesangioproliferative glomerulonephritis: new insights into mechanisms.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atenolol; Benzimidazoles; | 2013 |
POSSIBLY THIAZIDE-INDUCED RENAL NECROTISING VASCULITIS.
Topics: Chlorothiazide; Hydrochlorothiazide; Inflammation; Kidney Diseases; Necrosis; Pathology; Skin Diseas | 1965 |
Effects of eprosartan versus hydrochlorothiazide on markers of vascular oxidation and inflammation and blood pressure (renin-angiotensin system antagonists, oxidation, and inflammation).
Topics: Acrylates; Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Chemoki | 2002 |
Chronic hypernatremia associated with inflammation of the neurohypophysis.
Topics: Aged; Chronic Disease; Dehydration; Female; Humans; Hydrochlorothiazide; Hypernatremia; Inflammation | 1970 |