Compounds > hydrochlorothiazide
Page last updated: 2024-10-28

hydrochlorothiazide and Indigestion

hydrochlorothiazide has been researched along with Indigestion in 1 studies

Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.

Research Excerpts

ExcerptRelevanceReference
"Aliskiren treatment, both as monotherapy and with optional addition of amlodipine, provided significantly greater BP reductions than the respective hydrochlorothiazide regimens."2.74Long-term antihypertensive efficacy and safety of the oral direct renin inhibitor aliskiren: a 12-month randomized, double-blind comparator trial with hydrochlorothiazide. ( Botha, J; Gorostidi, M; Guerediaga, J; Maboudian, M; Philipp, T; Schmieder, RE; Smith, B; van Ingen, H; Weissbach, N, 2009)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schmieder, RE1
Philipp, T1
Guerediaga, J1
Gorostidi, M1
Smith, B1
Weissbach, N1
Maboudian, M1
Botha, J1
van Ingen, H1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Twenty Six-week, Randomized, Double-blind, Parallel Group, Multicenter, Active Controlled, Dose Titration Study to Evaluate the Efficacy and Safety of Aliskiren Compared to HCTZ With the Optional Addition of Amlodipine, Followed by a Second Twenty Six W[NCT00219154]Phase 31,125 participants (Actual)Interventional2005-03-31Completed
A Twenty Six-week, Dose Titration Study to Evaluate the Efficacy and Safety of Aliskiren Compared to HCTZ With the Optional Addition of Amlodipine, Followed by a Second Twenty Six Weeks of Blinded Treatment, in Patients With Essential Hypertension[NCT00294710]Phase 3976 participants (Actual)Interventional2005-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for hydrochlorothiazide and Indigestion

ArticleYear
Long-term antihypertensive efficacy and safety of the oral direct renin inhibitor aliskiren: a 12-month randomized, double-blind comparator trial with hydrochlorothiazide.
    Circulation, 2009, Jan-27, Volume: 119, Issue:3

    Topics: Administration, Oral; Adult; Aged; Amides; Antihypertensive Agents; Double-Blind Method; Dyspepsia;

2009
Long-term antihypertensive efficacy and safety of the oral direct renin inhibitor aliskiren: a 12-month randomized, double-blind comparator trial with hydrochlorothiazide.
    Circulation, 2009, Jan-27, Volume: 119, Issue:3

    Topics: Administration, Oral; Adult; Aged; Amides; Antihypertensive Agents; Double-Blind Method; Dyspepsia;

2009
Long-term antihypertensive efficacy and safety of the oral direct renin inhibitor aliskiren: a 12-month randomized, double-blind comparator trial with hydrochlorothiazide.
    Circulation, 2009, Jan-27, Volume: 119, Issue:3

    Topics: Administration, Oral; Adult; Aged; Amides; Antihypertensive Agents; Double-Blind Method; Dyspepsia;

2009
Long-term antihypertensive efficacy and safety of the oral direct renin inhibitor aliskiren: a 12-month randomized, double-blind comparator trial with hydrochlorothiazide.
    Circulation, 2009, Jan-27, Volume: 119, Issue:3

    Topics: Administration, Oral; Adult; Aged; Amides; Antihypertensive Agents; Double-Blind Method; Dyspepsia;

2009