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hydrochlorothiazide and Hyponatremia

hydrochlorothiazide has been researched along with Hyponatremia in 77 studies

Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.

Hyponatremia: Deficiency of sodium in the blood; salt depletion. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
" We investigated the association of clinical variables and cardiovascular drugs, including furosemide, hydrochlorothiazide, spironolactone, and their doses, with the presence of hyponatremia at admission."7.96Furosemide and spironolactone doses and hyponatremia in patients with heart failure. ( Bušić, Ž; Čulić, V; Jurić Paić, M; Velat, I, 2020)
"To investigate differences in risk of hyponatremia between chlorthalidone and hydrochlorothiazide, adjusted for daily dose, we conducted a population-based case-control study within the Dutch IPCI (Integrated Primary Care Information) database."7.80Risk of hyponatremia with diuretics: chlorthalidone versus hydrochlorothiazide. ( Rodenburg, EM; Straus, SM; Stricker, BH; Sturkenboom, MC; van Blijderveen, JC; Verhamme, KM; Zietse, R, 2014)
"Some evidence suggests that chlorthalidone may be superior to hydrochlorothiazide for the treatment of hypertension."7.79Chlorthalidone versus hydrochlorothiazide for the treatment of hypertension in older adults: a population-based cohort study. ( Dhalla, IA; Gomes, T; Hellings, C; Juurlink, DN; Mamdani, MM; Nagge, J; Persaud, N; Yao, Z, 2013)
"The clinical course of losartan potassium/hydrochlorothiazide (Preminent(®))-induced hyponatremia has not been described."7.77Losartan potassium/hydrochlorothiazide (Preminent®) and hyponatremia: case series of 40 patients. ( Fujiki, K; Kinoshita, H; Kobayashi, K; Koga, N; Tomiyama, J; Yaguramaki, T; Yakushiji, F; Yasuda, M, 2011)
" In this case report, significant hyperkalemia and hyponatremia related to telmisartan/hydrochlorothiazide use in a diabetic patient has been presented."7.76Significant hyperkalemia and hyponatremia secondary to telmisartan/hydrochlorothiazide treatment. ( Cakir, M, 2010)
"In order to determine how both diuretics affect water metabolism, we here compare the effects of a rechallenge with either amiloride-hydrochlorothiazide fixed association (AmHTZ; amiloride chlorhydrate 5 mg+hydrochlorothiazide 50 mg; Moduretic) or furosemide (F; 40 mg; Lasix) on water excretion in a 79 year old woman who was previously admitted for severe symptomatic hyponatremia secondary to a 5 days course of AmHTZ for systolic hypertension."7.75Safety of furosemide administration in an elderly woman recovered from thiazide-induced hyponatremia. ( Cogan, E; Fadel, S; Karmali, R, 2009)
"Although carbamazepine is known to cause hyponatremia, no previous reports have indicated an interaction between carbamazepine and a diuretic."7.67Carbamazepine, diuretics, and hyponatremia: a possible interaction. ( Beland, F; Belzile, L; Camille, Y; Henderson, M; Nastase, C; Yassa, R, 1987)
"We present three aged female patients who fulfil the criteria of a syndrome that we call "amiloride hyponatremia"."7.66Amiloride-induced hyponatremia. ( Huikko, M; Rossi, M; Tarssanen, L, 1980)
"Hyponatremia is the most frequently encountered electrolyte abnormality among hospitalized patients and thiazide users."5.39Prevalence of hyponatremia among patients who used indapamide and hydrochlorothiazide: a single center retrospective study. ( Abukhalid, N; Al Ammari, M; Al Johani, N; Al Qahtani, M; Al Sayyari, A; Al Swaidan, L; Alshahrani, A; Alskaini, A; Binsalih, S; Theaby, A, 2013)
"Even when the hyponatremia is carefully corrected, the encephalopathy may deteriorate in the course of treatment."5.35[Hyponatremia, rhabdomyolysis and encephalopathy after taking hydrochlorothiazide and drinking tea]. ( Eckrich, K; Fritzsch, J, 2009)
" Alcohol consumption, female sex, n-terminal pro-brain natriuretic peptide (NT-proBNP), hydrochlorothiazide (HCT), and mineralocorticoid receptor antagonist (MRA) use, or angiotensin II receptor I blocker (ARB) non-use were associated with hyponatremia in patients with normal renal function (p ≤ 0."4.12Clinical predictors of hyponatremia in patients with heart failure according to severity of chronic kidney disease. ( Bušić, Ž; Čulić, V; Velat, I, 2022)
" She had a known case of hypertension and was recently started on hydrochlorothiazide."3.96Sequential Drug-Induced Severe Hyponatremia in a Minimally Symptomatic, 81-Year-Old Patient. ( Akeely, Y; Lin, LC; Vilke, GM, 2020)
" We investigated the association of clinical variables and cardiovascular drugs, including furosemide, hydrochlorothiazide, spironolactone, and their doses, with the presence of hyponatremia at admission."3.96Furosemide and spironolactone doses and hyponatremia in patients with heart failure. ( Bušić, Ž; Čulić, V; Jurić Paić, M; Velat, I, 2020)
"Some evidence suggests that chlorthalidone may be superior to hydrochlorothiazide for the treatment of hypertension."3.79Chlorthalidone versus hydrochlorothiazide for the treatment of hypertension in older adults: a population-based cohort study. ( Dhalla, IA; Gomes, T; Hellings, C; Juurlink, DN; Mamdani, MM; Nagge, J; Persaud, N; Yao, Z, 2013)
"The clinical course of losartan potassium/hydrochlorothiazide (Preminent(®))-induced hyponatremia has not been described."3.77Losartan potassium/hydrochlorothiazide (Preminent®) and hyponatremia: case series of 40 patients. ( Fujiki, K; Kinoshita, H; Kobayashi, K; Koga, N; Tomiyama, J; Yaguramaki, T; Yakushiji, F; Yasuda, M, 2011)
" In this case report, significant hyperkalemia and hyponatremia related to telmisartan/hydrochlorothiazide use in a diabetic patient has been presented."3.76Significant hyperkalemia and hyponatremia secondary to telmisartan/hydrochlorothiazide treatment. ( Cakir, M, 2010)
"In order to determine how both diuretics affect water metabolism, we here compare the effects of a rechallenge with either amiloride-hydrochlorothiazide fixed association (AmHTZ; amiloride chlorhydrate 5 mg+hydrochlorothiazide 50 mg; Moduretic) or furosemide (F; 40 mg; Lasix) on water excretion in a 79 year old woman who was previously admitted for severe symptomatic hyponatremia secondary to a 5 days course of AmHTZ for systolic hypertension."3.75Safety of furosemide administration in an elderly woman recovered from thiazide-induced hyponatremia. ( Cogan, E; Fadel, S; Karmali, R, 2009)
"We have presented five episodes of hydrochlorothiazide-induced hyponatremia in three elderly nursing home patients."3.67Hyponatremia induced by thiazide-like diuretics in the elderly. ( Denham, JW; Oles, KS, 1984)
"Although carbamazepine is known to cause hyponatremia, no previous reports have indicated an interaction between carbamazepine and a diuretic."3.67Carbamazepine, diuretics, and hyponatremia: a possible interaction. ( Beland, F; Belzile, L; Camille, Y; Henderson, M; Nastase, C; Yassa, R, 1987)
"We present three aged female patients who fulfil the criteria of a syndrome that we call "amiloride hyponatremia"."3.66Amiloride-induced hyponatremia. ( Huikko, M; Rossi, M; Tarssanen, L, 1980)
"Hyponatremia is a common cause of morbidity in the elderly, and thiazide diuretics are often implicated."2.67Increased susceptibility to thiazide-induced hyponatremia in the elderly. ( Clark, BA; Epstein, FH; Rosa, RM; Shannon, RP, 1994)
"Hyponatremia is a potentially serious complication of the use of SSRIs and is statistically more prevalent in the elderly and in females."2.44Hyponatremia as a complication of selective serotonin reuptake inhibitors. ( Schroeter, S; Wright, SK, 2008)
"Hyponatremia is a reported, though uncommon, complication of thiazide use."1.42Severe hyponatremia associated with thiazide diuretic use. ( Eilbert, WP; Sardar, GK, 2015)
"Hyponatremia was corrected after withdrawal of HCT and fluid restriction and central nervous symptoms disappeared rapidly."1.42[Can water be poisonous?]. ( Amend, B; Artunc, F; Gallwitz, B; Schnauder, G, 2015)
"Hyponatremia is the most frequently encountered electrolyte abnormality among hospitalized patients and thiazide users."1.39Prevalence of hyponatremia among patients who used indapamide and hydrochlorothiazide: a single center retrospective study. ( Abukhalid, N; Al Ammari, M; Al Johani, N; Al Qahtani, M; Al Sayyari, A; Al Swaidan, L; Alshahrani, A; Alskaini, A; Binsalih, S; Theaby, A, 2013)
"Even when the hyponatremia is carefully corrected, the encephalopathy may deteriorate in the course of treatment."1.35[Hyponatremia, rhabdomyolysis and encephalopathy after taking hydrochlorothiazide and drinking tea]. ( Eckrich, K; Fritzsch, J, 2009)
"Xipamide is a sulfonamide-like diuretic whose action does not depend on transtubular secretion."1.31Severe electrolyte disturbances and renal failure in elderly patients with combined diuretic therapy including xipamid. ( Bellmann, R; Heininger, D; Joannidis, M; Kähler, C; Sandhofer, A; Wiedermann, CJ, 2002)
"A 54-year-old woman had seizures and a focal neurologic deficit associated with hyponatremia induced by a thiazide diuretic."1.27Thiazide-induced hyponatremia. ( Johnson, JE; Wright, LF, 1983)

Research

Studies (77)

TimeframeStudies, this research(%)All Research%
pre-199033 (42.86)18.7374
1990's16 (20.78)18.2507
2000's12 (15.58)29.6817
2010's13 (16.88)24.3611
2020's3 (3.90)2.80

Authors

AuthorsStudies
Velat, I2
Bušić, Ž2
Čulić, V2
Vilke, GM1
Akeely, Y1
Lin, LC1
Jurić Paić, M1
Liang, W1
Ma, H1
Cao, L1
Yan, W1
Yang, J1
Chakraborty, S1
Bhattacharya, C1
Das, S1
Sen, S1
Al Qahtani, M1
Alshahrani, A1
Alskaini, A1
Abukhalid, N1
Al Johani, N1
Al Ammari, M1
Al Swaidan, L1
Binsalih, S1
Al Sayyari, A1
Theaby, A1
Dhalla, IA1
Gomes, T1
Yao, Z1
Nagge, J1
Persaud, N1
Hellings, C1
Mamdani, MM1
Juurlink, DN1
van Blijderveen, JC1
Straus, SM1
Rodenburg, EM1
Zietse, R1
Stricker, BH1
Sturkenboom, MC1
Verhamme, KM1
Frenkel, NJ1
Vogt, L1
De Rooij, SE1
Trimpert, C1
Levi, MM1
Deen, PM1
van den Born, BJ1
Chen, SH1
Karanjia, R1
Chevrier, RL1
Marshall, DH1
Sardar, GK1
Eilbert, WP1
Artunc, F1
Schnauder, G2
Gallwitz, B1
Amend, B1
Fadel, S1
Karmali, R1
Cogan, E1
Fritzsch, J1
Eckrich, K1
Mantel, K1
Cakir, M1
Kinoshita, H1
Kobayashi, K1
Yaguramaki, T1
Yasuda, M1
Fujiki, K1
Tomiyama, J1
Koga, N1
Yakushiji, F1
Zürn, CS1
Sauer-Schulz, A1
Coler, C1
Hoffman, MD1
Towle, G1
Hew-Butler, T1
Sharabi, Y1
Illan, R1
Kamari, Y1
Cohen, H1
Nadler, M1
Messerli, FH1
Grossman, E1
Sandhofer, A1
Kähler, C1
Heininger, D1
Bellmann, R1
Wiedermann, CJ1
Joannidis, M1
WINER, BM1
BAGROS, P1
LYON, AF1
DEGRAFF, AC1
WOHLRABE, JC1
PITTS, FN1
Rosner, MH1
Ranta, A1
Wooten, GF1
Wright, SK1
Schroeter, S1
Fitzgerald, MA1
Roberts, CJ1
Channer, KS1
Bungay, D1
Zalin, AM1
Hutchinson, CE1
Jong, M1
Matthews, K1
Millson, D1
Borland, C1
Murphy, P1
Davison, W1
Eastell, R1
Edmonds, CJ1
Emsley, RA2
Gledhill, RF1
Oles, KS1
Denham, JW1
Donaldson, M1
Mackay, M1
Johnson, JE1
Wright, LF1
Strykers, PH1
Stern, RS1
Morse, BM1
Ponte, CD1
Tarssanen, L2
Huikko, M1
Rossi, M1
Clark, BA1
Shannon, RP1
Rosa, RM1
Epstein, FH1
Haensch, CA1
Hennen, G1
Jörg, J1
Hornick, P2
Voegeli, J1
Baumann, P1
De Jong, MJ1
Phillips, PJ1
Tallis, GA1
Popplewell, PY1
van Assen, S1
Mudde, AH1
Riquelme, A1
Méndez, F1
Ortiz, AM1
Müller, H1
Campos, C1
Rocha, V1
Valdivieso, A1
Al-Salman, J1
Pursell, R1
Chapman, MD1
Hanrahan, R1
McEwen, J1
Marley, JE1
Pinnock, CA1
Gossain, VV1
Hagen, GA1
Sugawara, M1
Bianchi Porre, G1
Lazzaroni, M1
Petrillo, M1
Pais, P1
Muller, RJ1
Lann, HD1
Mouallem, M1
Friedman, E1
Shemesh, Y1
Mayan, H1
Pauzner, R1
Farfel, Z1
Allen, P1
Byatt, CM2
Millard, PH1
Levin, GE1
Mathew, TH1
Boyd, IW1
Rohan, AP1
van der Meer, H1
Aalbers, C1
Taljaard, JJ1
Johnston, C1
Webb, L1
Daley, J1
Spathis, GS1
Benfield, GF1
Haffner, C1
Harris, P1
Stableforth, DE1
Bain, PG1
Egner, W1
Walker, PR1
Canning, G1
McKillop, G1
Slater, SD1
Mathiassen, B1
Kromann-Andersen, H1
Yassa, R1
Nastase, C1
Camille, Y1
Henderson, M1
Belzile, L1
Beland, F1
Greenberg, A1
Kone, B1
Gimenez, L1
Watson, AJ1
Mataverde, AQ1
Abbasi, AA1
Hossain, Z1
Bissell, GW1
Paris, GL1
Macoul, KL1
Fichman, MP1
Vorherr, H1
Kleeman, CR1
Telfer, N1
Beresford, HR1

Reviews

3 reviews available for hydrochlorothiazide and Hyponatremia

ArticleYear
Comparison of thiazide-like diuretics versus thiazide-type diuretics: a meta-analysis.
    Journal of cellular and molecular medicine, 2017, Volume: 21, Issue:11

    Topics: Antihypertensive Agents; Blood Glucose; Blood Pressure; Chlorthalidone; Cholesterol; Diuretics; Huma

2017
Hyponatremia as a complication of selective serotonin reuptake inhibitors.
    Journal of the American Academy of Nurse Practitioners, 2008, Volume: 20, Issue:1

    Topics: Aged; Aged, 80 and over; Depressive Disorder; Drug Interactions; Drug Therapy, Combination; Female;

2008
Hyponatraemia and Moduretic-grand mal seizures: a review.
    Journal of the Royal Society of Medicine, 1989, Volume: 82, Issue:8

    Topics: Aged; Amiloride; Drug Combinations; Epilepsy, Tonic-Clonic; Female; Humans; Hydrochlorothiazide; Hyp

1989

Trials

2 trials available for hydrochlorothiazide and Hyponatremia

ArticleYear
Increased susceptibility to thiazide-induced hyponatremia in the elderly.
    Journal of the American Society of Nephrology : JASN, 1994, Volume: 5, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Creatinine; Diuresis; Female; Humans; Hydrochlorothiazi

1994
[Letter: Ascrtogenicliver cirrhosis. Effect of amiloride on water-electrolytemetabolsim].
    La Nouvelle presse medicale, 1975, Apr-05, Volume: 4, Issue:14

    Topics: Amiloride; Ascites; Chlorides; Clinical Trials as Topic; Furosemide; Humans; Hydrochlorothiazide; Hy

1975

Other Studies

72 other studies available for hydrochlorothiazide and Hyponatremia

ArticleYear
Clinical predictors of hyponatremia in patients with heart failure according to severity of chronic kidney disease.
    Wiener klinische Wochenschrift, 2022, Volume: 134, Issue:17-18

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Calcium Chan

2022
Sequential Drug-Induced Severe Hyponatremia in a Minimally Symptomatic, 81-Year-Old Patient.
    The Journal of emergency medicine, 2020, Volume: 58, Issue:3

    Topics: Aged, 80 and over; Diuretics; Female; Humans; Hydrochlorothiazide; Hypertension; Hyponatremia; Salin

2020
Furosemide and spironolactone doses and hyponatremia in patients with heart failure.
    BMC pharmacology & toxicology, 2020, 08-03, Volume: 21, Issue:1

    Topics: Aged; Aged, 80 and over; Diuretics; Female; Furosemide; Heart Failure; Hospitalization; Humans; Hydr

2020
Delta check: a must in the management of hyponatremia.
    Clinical chemistry and laboratory medicine, 2013, Volume: 51, Issue:7

    Topics: Antihypertensive Agents; Confusion; Fatal Outcome; Humans; Hydrochlorothiazide; Hyponatremia; Male;

2013
Prevalence of hyponatremia among patients who used indapamide and hydrochlorothiazide: a single center retrospective study.
    Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2013, Volume: 24, Issue:2

    Topics: Adolescent; Age Factors; Aged; Aged, 80 and over; Biomarkers; Chi-Square Distribution; Comorbidity;

2013
Chlorthalidone versus hydrochlorothiazide for the treatment of hypertension in older adults: a population-based cohort study.
    Annals of internal medicine, 2013, Mar-19, Volume: 158, Issue:6

    Topics: Aged; Antihypertensive Agents; Chlorthalidone; Follow-Up Studies; Hospitalization; Humans; Hydrochlo

2013
Risk of hyponatremia with diuretics: chlorthalidone versus hydrochlorothiazide.
    The American journal of medicine, 2014, Volume: 127, Issue:8

    Topics: Adolescent; Adult; Aged; Case-Control Studies; Chlorthalidone; Diuretics; Female; Humans; Hydrochlor

2014
Thiazide-induced hyponatraemia is associated with increased water intake and impaired urea-mediated water excretion at low plasma antidiuretic hormone and urine aquaporin-2.
    Journal of hypertension, 2015, Volume: 33, Issue:3

    Topics: Aged; Aged, 80 and over; Aquaporin 2; Drinking; Electrolytes; Female; Humans; Hydrochlorothiazide; H

2015
Bilateral acute angle closure glaucoma associated with hydrochlorothiazide-induced hyponatraemia.
    BMJ case reports, 2014, Dec-04, Volume: 2014

    Topics: Aged; Antihypertensive Agents; Diagnosis, Differential; Female; Glaucoma, Angle-Closure; Headache; H

2014
Severe hyponatremia associated with thiazide diuretic use.
    The Journal of emergency medicine, 2015, Volume: 48, Issue:3

    Topics: Aged; Humans; Hydrochlorothiazide; Hyponatremia; Male; Sodium Chloride Symporter Inhibitors

2015
[Can water be poisonous?].
    Deutsche medizinische Wochenschrift (1946), 2015, Volume: 140, Issue:23

    Topics: Aged, 80 and over; Diagnosis, Differential; Drinking; Female; Humans; Hydrochlorothiazide; Hyponatre

2015
Safety of furosemide administration in an elderly woman recovered from thiazide-induced hyponatremia.
    European journal of internal medicine, 2009, Volume: 20, Issue:1

    Topics: Aged; Diuretics; Drinking; Female; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Hyponatrem

2009
[Hyponatremia, rhabdomyolysis and encephalopathy after taking hydrochlorothiazide and drinking tea].
    Deutsche medizinische Wochenschrift (1946), 2009, Volume: 134, Issue:14

    Topics: Beverages; Brain Diseases; Diuretics; Female; Humans; Hydrochlorothiazide; Hyponatremia; Isotonic So

2009
[Hyponatremia, rhabdomyolysis and encephalopathy after taking hydrochlorothiazide and tea].
    Deutsche medizinische Wochenschrift (1946), 2009, Volume: 134, Issue:28-29

    Topics: Antihypertensive Agents; Beverages; Brain Diseases; Diuretics; Drinking; Female; Humans; Hydrochloro

2009
Significant hyperkalemia and hyponatremia secondary to telmisartan/hydrochlorothiazide treatment.
    Blood pressure, 2010, Volume: 19, Issue:6

    Topics: Aged; Benzimidazoles; Benzoates; Blood Pressure; Drug Combinations; Humans; Hydrochlorothiazide; Hyp

2010
Losartan potassium/hydrochlorothiazide (Preminent®) and hyponatremia: case series of 40 patients.
    Human & experimental toxicology, 2011, Volume: 30, Issue:9

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Female; Humans; Hydrochlorothia

2011
[Hyponatremia--should it be ignored or diagnosed?--Case 8/2011].
    Deutsche medizinische Wochenschrift (1946), 2011, Volume: 136, Issue:34-35

    Topics: Aged; Algorithms; Amiloride; Dehydration; Diagnosis, Differential; Diuretics; Drug Therapy, Combinat

2011
Hyponatremia in an 85-year-old hiker: when depletion plus dilution produces delirium.
    Wilderness & environmental medicine, 2012, Volume: 23, Issue:2

    Topics: Age Factors; Aged, 80 and over; Antihypertensive Agents; Arginine Vasopressin; Delirium; Drinking; E

2012
Diuretic induced hyponatraemia in elderly hypertensive women.
    Journal of human hypertension, 2002, Volume: 16, Issue:9

    Topics: Aged; Aged, 80 and over; Diuretics; Female; Humans; Hydrochlorothiazide; Hypertension; Hyponatremia;

2002
Hypokalaemia and hyponatraemia due to indapamide.
    Prescrire international, 2002, Volume: 11, Issue:62

    Topics: Amiloride; Australia; France; Humans; Hydrochlorothiazide; Hypokalemia; Hyponatremia; Indapamide; Ph

2002
Severe electrolyte disturbances and renal failure in elderly patients with combined diuretic therapy including xipamid.
    Wiener klinische Wochenschrift, 2002, Nov-30, Volume: 114, Issue:21-22

    Topics: Age Factors; Aged; Aged, 80 and over; Diuretics; Drug Therapy, Combination; Emergencies; Female; Fur

2002
The antihypertensive mechanisms of salt depletion induced by hydrochlorothiazide.
    Circulation, 1961, Volume: 24

    Topics: Antihypertensive Agents; Chlorothiazide; Hydrochlorothiazide; Hypertension; Hyponatremia; Sodium; So

1961
[THE TREATMENT OF EDEMA WITH SULFONAMIDE DIURETICS].
    Vie medicale (Paris, France : 1920), 1964, Volume: 45

    Topics: Acetazolamide; Acidosis; Benzothiadiazines; Chlorothiazide; Chlorthalidone; Dehydration; Diuretics;

1964
DIURETIC THERAPY. VI. METABOLIC COMPLICATIONS OF THIAZIDE THERAPY AND THEIR CORRECTION.
    American heart journal, 1964, Volume: 68

    Topics: Bendroflumethiazide; Blood; Blood Urea Nitrogen; Diuretics; Humans; Hydrochlorothiazide; Hyperglycem

1964
DELIRIUM AND COMPLEX ELECTROLYTE DISTURBANCE.
    Diseases of the nervous system, 1965, Volume: 26

    Topics: Alkalosis; Chlorothiazide; Delirium; Diet, Sodium-Restricted; Drug Therapy; Electrolytes; Hydrochlor

1965
Severe hyponatremia associated with the combined use of thiazide diuretics and selective serotonin reuptake inhibitors.
    The American journal of the medical sciences, 2004, Volume: 327, Issue:2

    Topics: Aged; Aged, 80 and over; Depression; Diuretics; Female; Humans; Hydrochlorothiazide; Hypertension; H

2004
Hyponatremia due to an additive effect of carbamazepine and thiazide diuretics.
    Epilepsia, 2004, Volume: 45, Issue:7

    Topics: Anticonvulsants; Carbamazepine; Comorbidity; Diuretics; Drug Interactions; Epilepsy, Complex Partial

2004
Hyponatremia associated with SSRI use in a 65-year-old woman.
    The Nurse practitioner, 2008, Volume: 33, Issue:2

    Topics: Depressive Disorder; Diuretics; Drug Monitoring; Drug Synergism; Dyslipidemias; Female; Humans; Hydr

2008
Hyponatraemia induced by a combination of hydrochlorothiazide and triamterene.
    British medical journal (Clinical research ed.), 1984, Jun-30, Volume: 288, Issue:6435

    Topics: Adult; Drug Combinations; Drug Synergism; Female; Humans; Hydrochlorothiazide; Hyponatremia; Triamte

1984
Hyponatraemia during treatment with chlorpropamide and Moduretic (amiloride plus hydrochlorothiazide).
    British medical journal (Clinical research ed.), 1984, Sep-15, Volume: 289, Issue:6446

    Topics: Aged; Amiloride; Chlorpropamide; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Fe

1984
Hyponatraemia and Moduretic (amiloride plus hydrochlorothiazide)
    British medical journal (Clinical research ed.), 1984, Nov-10, Volume: 289, Issue:6454

    Topics: Aged; Amiloride; Drug Combinations; Humans; Hydrochlorothiazide; Hyponatremia; Pyrazines

1984
Hyponatraemia associated with trimethoprim and a diuretic.
    British medical journal (Clinical research ed.), 1984, Dec-15, Volume: 289, Issue:6459

    Topics: Aged; Amiloride; Body Weight; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrochl

1984
Thiazides, compulsive water drinking and hyponatraemic encephalopathy.
    Journal of neurology, neurosurgery, and psychiatry, 1984, Volume: 47, Issue:8

    Topics: Brain Diseases; Compulsive Behavior; Drinking; Female; Humans; Hydrochlorothiazide; Hypertension; Hy

1984
Hyponatremia induced by thiazide-like diuretics in the elderly.
    Southern medical journal, 1984, Volume: 77, Issue:10

    Topics: Aged; Diuretics; Edema; Female; Humans; Hydrochlorothiazide; Hypertension; Hyponatremia; Monitoring,

1984
Combination diuretics in the elderly.
    The Medical journal of Australia, 1983, Feb-05, Volume: 1, Issue:3

    Topics: Aged; Aged, 80 and over; Amiloride; Drug Combinations; Humans; Hydrochlorothiazide; Hypokalemia; Hyp

1983
Hyponatraemia and diuretics.
    The New Zealand medical journal, 1983, Aug-10, Volume: 96, Issue:737

    Topics: Aged; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hyponatremia; Middle Aged;

1983
Thiazide-induced hyponatremia.
    Southern medical journal, 1983, Volume: 76, Issue:11

    Topics: Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Hyponatremia; Middle Aged; Neu

1983
Hyponatremia induced by a combination of amiloride and hydrochlorothiazide.
    JAMA, 1984, Jul-20, Volume: 252, Issue:3

    Topics: Aged; Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Hyponatremia;

1984
A suspected case of thiazide-induced hyponatremia.
    Drug intelligence & clinical pharmacy, 1982, Volume: 16, Issue:9

    Topics: Aged; Body Water; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Hyponatremia; Male; Sodium C

1982
[Hyponatremia associated with diuretic therapy in an elderly patient].
    Duodecim; laaketieteellinen aikakauskirja, 1981, Volume: 97, Issue:22

    Topics: Aged; Amiloride; Female; Humans; Hydrochlorothiazide; Hyponatremia; Pyrazines

1981
Amiloride-induced hyponatremia.
    Acta medica Scandinavica, 1980, Volume: 208, Issue:6

    Topics: Aged; Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hyponatremia; Pyrazines

1980
[Reversible exogenous psychosis in thiazide-induced hyponatremia of 97 mmol/l].
    Der Nervenarzt, 1996, Volume: 67, Issue:4

    Topics: Adult; Amputation, Surgical; Arterial Occlusive Diseases; Diuretics; Drug Therapy, Combination; Fema

1996
Severe hyponatraemia in elderly patients: cause for concern.
    Annals of the Royal College of Surgeons of England, 1996, Volume: 78, Issue:3 ( Pt 1)

    Topics: Aged; Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hyponatremia; Postoperative

1996
Inappropriate secretion of antidiuretic hormone and SSRIs.
    The British journal of psychiatry : the journal of mental science, 1996, Volume: 169, Issue:4

    Topics: Aged; Bipolar Disorder; Citalopram; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide;

1996
Emergency! Hyponatremia.
    The American journal of nursing, 1998, Volume: 98, Issue:12

    Topics: Aged; Diuretics; Emergencies; Female; Humans; Hydrochlorothiazide; Hypertension; Hyponatremia; Sodiu

1998
Could this be a drug side effect?
    Australian family physician, 1999, Volume: 28, Issue:3

    Topics: Aged; Amiloride; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Hyd

1999
Severe hyponatraemia in an amiloride/hydrochlorothiazide-treated patient.
    The Netherlands journal of medicine, 1999, Volume: 54, Issue:3

    Topics: Aged; Aged, 80 and over; Amiloride; Diagnosis, Differential; Diuretics; Drug Combinations; Female; H

1999
[Severe and recent hyponatremia and hypokalemia associated to the use of hydrochlorothiazide, enalapril and citalopram. Clinical case].
    Revista medica de Chile, 1999, Volume: 127, Issue:10

    Topics: Aged; Antidepressive Agents, Second-Generation; Antihypertensive Agents; Citalopram; Enalapril; Fema

1999
Hyponatremic encephalopathy induced by thiazides.
    The Western journal of medicine, 2001, Volume: 175, Issue:2

    Topics: Aged; Antihypertensive Agents; Brain Diseases, Metabolic; Female; Humans; Hydrochlorothiazide; Hypon

2001
Hyponatraemia and hypokalaemia due to indapamide.
    The Medical journal of Australia, 2002, Mar-04, Volume: 176, Issue:5

    Topics: Amiloride; Australia; Chlorothiazide; Diuretics; Drug Combinations; Drug Utilization; Humans; Hydroc

2002
Hyponatraemia associated with hydrochlorothiazide treatment.
    British medical journal, 1978, Jan-07, Volume: 1, Issue:6104

    Topics: Aged; Confusion; Humans; Hydrochlorothiazide; Hyponatremia

1978
Hyponatraemia associated with hydrochlorothiazide treatment.
    British medical journal, 1978, Jan-21, Volume: 1, Issue:6106

    Topics: Aged; Female; Humans; Hydrochlorothiazide; Hyponatremia; Male

1978
Drug-induced hyponatraemia in psychogenic polydipsia.
    Postgraduate medical journal, 1976, Volume: 52, Issue:613

    Topics: Humans; Hydrochlorothiazide; Hyponatremia; Male; Middle Aged; Psychophysiologic Disorders; Schizophr

1976
Diuretic induced hyponatraemia in the elderly.
    The Journal of the Association of Physicians of India, 1992, Volume: 40, Issue:9

    Topics: Aged; Diagnosis, Differential; Furosemide; Humans; Hydrochlorothiazide; Hypertension; Hypokalemia; H

1992
Thiazide diuretics and polydipsia in schizophrenic patients.
    The American journal of psychiatry, 1991, Volume: 148, Issue:3

    Topics: Adult; Drinking Behavior; Humans; Hydrochlorothiazide; Hypertension; Hyponatremia; Male; Schizophren

1991
Cardiac conduction defects associated with hyponatremia.
    Clinical cardiology, 1991, Volume: 14, Issue:2

    Topics: Adult; Aged; Amiloride; Cardiomyopathies; Female; Heart Block; Humans; Hydrochlorothiazide; Hyponatr

1991
Acute hyponatraemia following total hip replacement.
    The British journal of clinical practice, 1990, Volume: 44, Issue:12

    Topics: Acute Disease; Aged; Aged, 80 and over; Amiloride; Drug Combinations; Female; Hip Prosthesis; Humans

1990
Hyponatraemia and Moduretic-grand mal seizures.
    Journal of the Royal Society of Medicine, 1990, Volume: 83, Issue:3

    Topics: Amiloride; Drug Combinations; Epilepsy, Tonic-Clonic; Humans; Hydrochlorothiazide; Hyponatremia

1990
Diuretics and electrolyte disturbances in 1000 consecutive geriatric admissions.
    Journal of the Royal Society of Medicine, 1990, Volume: 83, Issue:11

    Topics: Age Factors; Aged; Amiloride; Diuretics; Drug Combinations; Drug Prescriptions; Humans; Hydrochlorot

1990
Hyponatraemia due to the combination of hydrochlorothiazide and amiloride (Moduretic): Australian spontaneous reports 1977-1988.
    The Medical journal of Australia, 1990, Mar-19, Volume: 152, Issue:6

    Topics: Aged; Aged, 80 and over; Amiloride; Australia; Drug Combinations; Female; Humans; Hydrochlorothiazid

1990
Inappropriate antidiuretic state in long-term psychiatric inpatients.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1990, Mar-17, Volume: 77, Issue:6

    Topics: Adult; Aged; Carbamazepine; Female; Humans; Hydrochlorothiazide; Hyponatremia; Inappropriate ADH Syn

1990
Dilutional hyponatraemia masquerading as subarachnoid haemorrhage in patient on hydrochlorothiazide/amiloride/timolol combined drug.
    Lancet (London, England), 1986, Aug-09, Volume: 2, Issue:8502

    Topics: Amiloride; Diagnosis, Differential; Drug Combinations; Drug Interactions; Female; Humans; Hydrochlor

1986
Thiazide-induced dilutional hyponatraemia masquerading as subarachnoid haemorrhage.
    Lancet (London, England), 1986, Sep-13, Volume: 2, Issue:8507

    Topics: Aged; Amiloride; Bendroflumethiazide; Diagnosis, Differential; Drug Combinations; Female; Heart Fail

1986
Dilutional hyponatraemia due to hydrochlorothiazide plus amiloride (Moduretic): not to be mistaken for the syndrome of inappropriate secretion of antidiuretic hormone (SIADH).
    The British journal of clinical practice, 1988, Volume: 42, Issue:1

    Topics: Aged; Aged, 80 and over; Amiloride; Diagnosis, Differential; Drug Combinations; Female; Humans; Hydr

1988
[Electrolyte disorders resulting from treatment with a diuretic combination of hydrochlorothiazide and amiloride. A case report with acute symptomatic hyponatremia and a review of reports to the National Board of Adverse Drug Reactions over a period of 10
    Ugeskrift for laeger, 1988, Oct-03, Volume: 150, Issue:40

    Topics: Acute Disease; Aged; Amiloride; Denmark; Drug Combinations; Electrolytes; Female; Humans; Hydrochlor

1988
Carbamazepine, diuretics, and hyponatremia: a possible interaction.
    The Journal of clinical psychiatry, 1987, Volume: 48, Issue:7

    Topics: Aged; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazi

1987
What's new in diuretic therapy.
    American family physician, 1986, Volume: 33, Issue:5

    Topics: Acetazolamide; Acid-Base Imbalance; Biological Transport; Diuretics; Drug Resistance; Ethacrynic Aci

1986
Thiazide-induced hyponatremia.
    Southern medical journal, 1986, Volume: 79, Issue:11

    Topics: Acute Disease; Aged; Drinking; Humans; Hydrochlorothiazide; Hyponatremia; Male

1986
Hydrochlorothiazide-induced water intoxication in myxedema.
    JAMA, 1974, Nov-18, Volume: 230, Issue:7

    Topics: Administration, Oral; Consciousness Disorders; Humans; Hydrochlorothiazide; Hyponatremia; Hypothyroi

1974
Reversible bullous retinal detachment in chronic renal disease.
    American journal of ophthalmology, 1969, Volume: 67, Issue:2

    Topics: Adult; Angiography; Diet; Female; Fluorescence; Humans; Hydrochlorothiazide; Hypertension, Renal; Hy

1969
Diuretic-induced hyponatremia.
    Annals of internal medicine, 1971, Volume: 75, Issue:6

    Topics: Adult; Aged; Alkalosis; Bendroflumethiazide; Biological Assay; Blood Urea Nitrogen; Bromine; Carbon

1971
Polydipsia, hydrochlorothiazide, and water intoxication.
    JAMA, 1970, Nov-02, Volume: 214, Issue:5

    Topics: Adult; Chlorides; Drinking; Female; Humans; Hydrochlorothiazide; Hyponatremia; Male; Middle Aged; Ne

1970