hydrochlorothiazide has been researched along with Hypocalcemia in 12 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
Hypocalcemia: Reduction of the blood calcium below normal. Manifestations include hyperactive deep tendon reflexes, Chvostek's sign, muscle and abdominal cramps, and carpopedal spasm. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The administration of calcitriol plus hydrochlorothiazide is able to prevent transient post-thyroidectomy hypocalcemia and to reduce hospital stay." | 9.12 | Calcitriol plus hydrochlorothiazide prevents transient post-thyroidectomy hypocalcemia. ( Castaldi, P; D'ugo, D; De Rosa, A; De Rosa, G; Fant, V; Fiore, GF; Grieco, V; Persiani, R; Rausei, S; Testa, A, 2006) |
| "Acute lymphoblastic leukemia (ALL) in children can rarely present with severe lactic acidosis in the absence of a high white blood cell count or other complications." | 1.32 | Acute lymphoblastic leukemia presenting with lactic acidosis and renal tubular dysfunction. ( Hayek, M; Srinivasan, A, 2003) |
| "Because treatment of the hypocalcemia with vitamin D and/or calcium in patients with such mutations results in increased hypercalciuria, nephrocalcinosis, and renal impairment, its use should be limited to alleviating the symptoms of symptomatic patients." | 1.31 | Hydrochlorothiazide effectively reduces urinary calcium excretion in two Japanese patients with gain-of-function mutations of the calcium-sensing receptor gene. ( Fujieda, K; Hasegawa, Y; Nakae, J; Nanao, K; Sato, K; Shinohara, N; Tajima, T; Takahashi, I, 2002) |
| "Treatment with hydrochlorothiazide is effective in patients without increased urinary excretion of prostaglandin, whereas patients with increased prostaglandin excretion respond better to indomethacin therapy." | 1.27 | [Clinical variants of idiopathic hypercalciuria in children]. ( Bachmann, H; Kohout, I, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (33.33) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Bossoni, S | 1 |
| Chiesa, L | 1 |
| Giustina, A | 1 |
| Ji, Y | 1 |
| Kang, C | 1 |
| Chen, J | 1 |
| Zhang, L | 1 |
| Hayek, M | 1 |
| Srinivasan, A | 1 |
| Suzuki, M | 1 |
| Aso, T | 1 |
| Sato, T | 1 |
| Michimata, M | 1 |
| Kazama, I | 1 |
| Saiki, H | 1 |
| Hatano, R | 1 |
| Ejima, Y | 1 |
| Miyama, N | 1 |
| Sato, A | 1 |
| Matsubara, M | 1 |
| Testa, A | 1 |
| Fant, V | 1 |
| De Rosa, A | 1 |
| Fiore, GF | 1 |
| Grieco, V | 1 |
| Castaldi, P | 1 |
| Persiani, R | 1 |
| Rausei, S | 1 |
| D'ugo, D | 1 |
| De Rosa, G | 1 |
| Sato, K | 1 |
| Hasegawa, Y | 1 |
| Nakae, J | 1 |
| Nanao, K | 1 |
| Takahashi, I | 1 |
| Tajima, T | 1 |
| Shinohara, N | 1 |
| Fujieda, K | 1 |
| Wong, CK | 1 |
| Pun, KK | 1 |
| Tam, SC | 1 |
| Tsui, EY | 1 |
| Kung, AW | 1 |
| Lam, KS | 1 |
| Wang, CC | 1 |
| Kurzel, RB | 1 |
| Hagen, GA | 1 |
| Kohout, I | 1 |
| Bachmann, H | 1 |
| Hubert, C | 1 |
| Demanet, JC | 1 |
| Degaute, JP | 1 |
| Fichefet, JP | 1 |
| Paduart, P | 1 |
| Raszeja-Wanic, B | 1 |
| Rampini, S | 1 |
| Fanconi, A | 1 |
| Illig, R | 1 |
| Prader, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Does Preoperative Calcium and Calcitriol Decrease Rates of Post Thyroidectomy Hypocalcemia?[NCT03869398] | 82 participants (Actual) | Interventional | 2017-08-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for hydrochlorothiazide and Hypocalcemia
| Article | Year |
|---|---|
[Effect of thiazide preparations on calcium levels in serum and urine].
Topics: Animals; Calcium; Dogs; Humans; Hydrochlorothiazide; Hypercalcemia; Hypocalcemia; Intestinal Absorpt | 1974 |
1 trial available for hydrochlorothiazide and Hypocalcemia
| Article | Year |
|---|---|
Calcitriol plus hydrochlorothiazide prevents transient post-thyroidectomy hypocalcemia.
Topics: Adult; Aged; Calcitriol; Calcium; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypocalc | 2006 |
10 other studies available for hydrochlorothiazide and Hypocalcemia
| Article | Year |
|---|---|
Severe hypocalcemia in a thyroidectomized woman with Covid-19 infection.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Betacoronavirus; Calcium; Calcium Gluconate; Coronav | 2020 |
Identification of p.Arg205Cys in CASR in an autosomal dominant hypocalcaemia type 1 pedigree: A case report.
Topics: Calcitriol; Calcium; DNA Mutational Analysis; Drug Therapy, Combination; Female; Genetic Testing; He | 2021 |
Acute lymphoblastic leukemia presenting with lactic acidosis and renal tubular dysfunction.
Topics: Acidosis, Lactic; Antineoplastic Combined Chemotherapy Protocols; Calcium; Child; Diuretics; Humans; | 2003 |
A case of gain-of-function mutation in calcium-sensing receptor: supplemental hydration is required for renal protection.
Topics: Administration, Oral; Calcium; Child; DNA; DNA Mutational Analysis; Extracellular Fluid; Female; Fol | 2005 |
Hydrochlorothiazide effectively reduces urinary calcium excretion in two Japanese patients with gain-of-function mutations of the calcium-sensing receptor gene.
Topics: Adolescent; Amino Acid Sequence; Base Sequence; Calcium; Cell Line; Cholecalciferol; Diuretics; Drug | 2002 |
Idiopathic hypercalciuria causing osteoporosis and hypocalcemia.
Topics: Adolescent; Calcitriol; Calcium; Calcium, Dietary; Female; Humans; Hydrochlorothiazide; Hypocalcemia | 1992 |
Use of thiazide diuretics to reduce the hypercalciuria of hypoparathyroidism during pregnancy.
Topics: Adult; Calcium; Diet, Sodium-Restricted; Female; Humans; Hydrochlorothiazide; Hypocalcemia; Hypopara | 1990 |
[Clinical variants of idiopathic hypercalciuria in children].
Topics: Aldosterone; Calcium; Child; Child, Preschool; Dinoprostone; Female; Humans; Hydrochlorothiazide; Hy | 1987 |
Tolerance and side-effects of the association hydrochlorothiazide-amiloride in long-term treatment of arterial hypertension.
Topics: Adult; Aged; Amiloride; Calcium; Creatinine; Drug Combinations; Drug Tolerance; Humans; Hydrochlorot | 1974 |
Effect of hydrochlorothiazide on proximal renal tubular acidosis in a patient with idiopathic "de toni-debré-fanconi syndrome".
Topics: Acidosis; Adolescent; Bicarbonates; Calcium; Fanconi Syndrome; Female; Humans; Hydrochlorothiazide; | 1968 |