hydrochlorothiazide has been researched along with Hypertrophy in 12 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study was aimed at assessing the effects of 1-year administration of the highly vasoselective calcium-channel blocker lercanidipine (10 mg/day) or the diuretic compound hydrochlorothiazide (25 mg/day) on hypertension-related vascular alterations." | 9.12 | Effects of long-term lercanidipine or hydrochlorothiazide administration on hypertension-related vascular structural changes. ( Cuspidi, C; Grassi, G; Mancia, G; Quarti-Trevano, F; Scopelliti, F; Seravalle, G, 2006) |
| " In the present study the effects of the angiotensin converting enzyme inhibitor (ACEI) enalapril and the thiazide-type diuretic, hydrochlorothiazide, on the development of the salt-induced left ventricular and kidney hypertrophy were examined in normotensive Wistar-Kyoto and Wistar rats." | 7.69 | Effects of enalapril and hydrochlorothiazide on the salt-induced cardiac and renal hypertrophy in normotensive rats. ( Karppanen, H; Laakso, J; Mervaala, EM; Vapaatalo, H, 1994) |
| " The present study was aimed at assessing the effects of 1-year administration of the highly vasoselective calcium-channel blocker lercanidipine (10 mg/day) or the diuretic compound hydrochlorothiazide (25 mg/day) on hypertension-related vascular alterations." | 5.12 | Effects of long-term lercanidipine or hydrochlorothiazide administration on hypertension-related vascular structural changes. ( Cuspidi, C; Grassi, G; Mancia, G; Quarti-Trevano, F; Scopelliti, F; Seravalle, G, 2006) |
| " The aim of this study was to compare the effects of an equivalent reduction in blood pressure produced by the angiotensin-converting enzyme (ACE) inhibitor spirapril (SPI) and an antihypertensive triple drug combination of hydralazine, reserpine and hydrochlorothiazide (HRH) on kidney function, proteinuria and renal structure in hypertensive diabetic rats." | 3.70 | Control of glomerular hyperfiltration and renal hypertrophy by an angiotensin converting enzyme inhibitor prevents the progression of renal damage in hypertensive diabetic rats. ( Armini, L; Bardelli, M; Calci, M; Campanacci, L; Candido, R; Carretta, R; Fabris, B; Fazio, M; Fischetti, F, 1999) |
| " In the present study the effects of the angiotensin converting enzyme inhibitor (ACEI) enalapril and the thiazide-type diuretic, hydrochlorothiazide, on the development of the salt-induced left ventricular and kidney hypertrophy were examined in normotensive Wistar-Kyoto and Wistar rats." | 3.69 | Effects of enalapril and hydrochlorothiazide on the salt-induced cardiac and renal hypertrophy in normotensive rats. ( Karppanen, H; Laakso, J; Mervaala, EM; Vapaatalo, H, 1994) |
| "Perindopril treatment also effectively prevented the development of vascular hypertrophy; however, treatment with hydralazine and hydrochlorothiazide was not as effective despite equivalent blood pressure reduction." | 1.30 | Different effects of antihypertensive agents on cardiac and vascular hypertrophy in the transgenic rat line TGR(mRen2)27. ( Brosnan, MJ; Clark, JS; Devlin, AM; Dominiczak, AF; Mullins, JJ, 1999) |
| "Renal hypertrophy was also decreased significantly by cicletanine at a dose of 100 mg/kg." | 1.27 | Comparison of cicletanine with other antihypertensive drugs in SHR-SP models. ( Braquet, P; Clostre, F; Le Hegarat, M; Malherbe, E, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (41.67) | 18.7374 |
| 1990's | 6 (50.00) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grassi, G | 1 |
| Quarti-Trevano, F | 1 |
| Scopelliti, F | 1 |
| Seravalle, G | 1 |
| Cuspidi, C | 1 |
| Mancia, G | 1 |
| Mervaala, EM | 1 |
| Laakso, J | 1 |
| Vapaatalo, H | 1 |
| Karppanen, H | 1 |
| Odum, J | 1 |
| Purkiss, J | 1 |
| Naish, PF | 1 |
| Brosnan, MJ | 1 |
| Devlin, AM | 1 |
| Clark, JS | 1 |
| Mullins, JJ | 1 |
| Dominiczak, AF | 1 |
| Giummelly, P | 1 |
| Lartaud-Idjouadiene, I | 1 |
| Marque, V | 1 |
| Niederhoffer, N | 1 |
| Chillon, JM | 1 |
| Capdeville-Atkinson, C | 1 |
| Atkinson, J | 1 |
| Fabris, B | 1 |
| Candido, R | 1 |
| Armini, L | 1 |
| Fischetti, F | 1 |
| Calci, M | 1 |
| Bardelli, M | 1 |
| Fazio, M | 1 |
| Campanacci, L | 1 |
| Carretta, R | 1 |
| Benstein, JA | 1 |
| Feiner, HD | 1 |
| Parker, M | 1 |
| Dworkin, LD | 1 |
| Yoshida, Y | 1 |
| Kawamura, T | 1 |
| Ikoma, M | 1 |
| Fogo, A | 1 |
| Ichikawa, I | 1 |
| Malherbe, E | 1 |
| Le Hegarat, M | 1 |
| Clostre, F | 1 |
| Braquet, P | 1 |
| Wiggelinkhuizen, J | 1 |
| Retief, PJ | 1 |
| Wolff, B | 1 |
| Fisher, RM | 1 |
| Cremin, BJ | 1 |
| Hofmann, LM | 1 |
| Sagartz, JW | 1 |
| Hall, CE | 1 |
| Holland, OB | 1 |
| Hall, O | 1 |
1 trial available for hydrochlorothiazide and Hypertrophy
| Article | Year |
|---|---|
Effects of long-term lercanidipine or hydrochlorothiazide administration on hypertension-related vascular structural changes.
Topics: Blood Vessels; Calcium Channel Blockers; Case-Control Studies; Dihydropyridines; Diuretics; Female; | 2006 |
11 other studies available for hydrochlorothiazide and Hypertrophy
| Article | Year |
|---|---|
Effects of enalapril and hydrochlorothiazide on the salt-induced cardiac and renal hypertrophy in normotensive rats.
Topics: Administration, Oral; Animals; Blood Pressure; Calcium; Cardiomegaly; Dose-Response Relationship, Dr | 1994 |
Influence of differing classes of antihypertensive agents on mesangial kinetics following partial renal ablation in rats.
Topics: Albuminuria; Animals; Antihypertensive Agents; Biological Transport, Active; Enalapril; Glomerular M | 1994 |
Different effects of antihypertensive agents on cardiac and vascular hypertrophy in the transgenic rat line TGR(mRen2)27.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive A | 1999 |
Effects of aging and antihypertensive treatment on aortic internal diameter in spontaneously hypertensive rats.
Topics: Age Factors; Aging; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihyp | 1999 |
Control of glomerular hyperfiltration and renal hypertrophy by an angiotensin converting enzyme inhibitor prevents the progression of renal damage in hypertensive diabetic rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Diabetic | 1999 |
Superiority of salt restriction over diuretics in reducing renal hypertrophy and injury in uninephrectomized SHR.
Topics: Animals; Diet, Sodium-Restricted; Diuretics; Hydrochlorothiazide; Hypertrophy; Kidney; Nephrectomy; | 1990 |
Effects of antihypertensive drugs on glomerular morphology.
Topics: Animals; Antihypertensive Agents; Enalapril; Glomerulonephritis; Glomerulosclerosis, Focal Segmental | 1989 |
Comparison of cicletanine with other antihypertensive drugs in SHR-SP models.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Captopril; Cardiomegaly; Diuresis; Di | 1988 |
Nephrogenic diabetes insipidus and obstructive uropathy.
Topics: Adolescent; Diabetes Insipidus; Diuretics; Female; Humans; Hydrochlorothiazide; Hydronephrosis; Hype | 1973 |
Effects of hydrochlorothiazide, spironolactone and metyrapone on electrolyte excretion and zona glomerulosa width in the sodium depleted rat.
Topics: Adrenal Gland Diseases; Adrenal Glands; Adrenal Medulla; Animals; Diet, Sodium-Restricted; Hydrochlo | 1970 |
Influence of hydrochlorothiazide on fluid consumption, blood pressure, and organ changes in rats subjected to hypersalimentation or augmented hypersalimentation.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Drinking; Hydrochlorothiazide; Hypertension; Hyper | 1968 |