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hydrochlorothiazide and Hyperparathyroidism

hydrochlorothiazide has been researched along with Hyperparathyroidism in 23 studies

Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.

Hyperparathyroidism: A condition of abnormally elevated output of PARATHYROID HORMONE (or PTH) triggering responses that increase blood CALCIUM. It is characterized by HYPERCALCEMIA and BONE RESORPTION, eventually leading to bone diseases. PRIMARY HYPERPARATHYROIDISM is caused by parathyroid HYPERPLASIA or PARATHYROID NEOPLASMS. SECONDARY HYPERPARATHYROIDISM is increased PTH secretion in response to HYPOCALCEMIA, usually caused by chronic KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
"We compared the effect of orally administered 100 mg of hydrochlorothiazide (HCTZ) among eight patients with pseudohypoparathyroidism (PHP) type I, 11 patients with idiopathic hypoparathyroidism (IHP), and 12 patients with primary hyperparathyroidism (1'HPT)."7.69The modulatory effect of endogenous parathyroid hormone on the action of hydrochlorothiazide in pseudohypoparathyroidism type I. ( Abe, K; Furukawa, Y; Mizunashi, K; Yoshinaga, K, 1994)
"Studies were undertaken in man to evaluate the roles of volume depletion and of the parathyroid glands in mediating the changes in serum and urinary calcium which follow the administration of hydrochlorothiazide, 100 mg twice daily, for 4 days, 42 studies were carried out in 16 normal subjects, 9 patients with hyperparathyroidism, and 7 vitamin D-treated subjects with hypoparathyroidism."5.03changes in serum and urinary calcium during treatment with hydrochlorothiazide: studies on mechanisms. ( Brickman, AS; Coburn, JW; Massry, SG, 1972)
"We compared the effect of orally administered 100 mg of hydrochlorothiazide (HCTZ) among eight patients with pseudohypoparathyroidism (PHP) type I, 11 patients with idiopathic hypoparathyroidism (IHP), and 12 patients with primary hyperparathyroidism (1'HPT)."3.69The modulatory effect of endogenous parathyroid hormone on the action of hydrochlorothiazide in pseudohypoparathyroidism type I. ( Abe, K; Furukawa, Y; Mizunashi, K; Yoshinaga, K, 1994)
"Treatment with hydrochlorothiazide 12."1.46Thiazide Treatment in Primary Hyperparathyroidism-A New Indication for an Old Medication? ( Benbassat, C; Diker-Cohen, T; Gorshtein, A; Herzberg, D; Hirsch, D; Masri-Iraqi, H; Shimon, I; Shochat, T; Shraga-Slutzky, I; Tsvetov, G, 2017)
"In study 3, stone recurrence, assessed prospectively, felt significantly in patients given a high fluid intake alone or associated with 50 mg/d of hydrochlorothiazide, independently of urinary calcium excretion."1.27[Predictive value of lithogenic risk in hypercalciuria: should 24-hour urine calcium be measured?]. ( Ulmann, A, 1984)
"Primary hyperparathyroidism is a major cause of calcium urolithiasis and is easily recognised when it is classically manifested."1.26Pitfalls in parathyroid evaluation in patients with calcium urolithiasis. ( Barilla, DE; Pak, CY, 1979)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199020 (86.96)18.7374
1990's2 (8.70)18.2507
2000's0 (0.00)29.6817
2010's1 (4.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tsvetov, G1
Hirsch, D1
Shimon, I1
Benbassat, C1
Masri-Iraqi, H1
Gorshtein, A1
Herzberg, D1
Shochat, T1
Shraga-Slutzky, I1
Diker-Cohen, T1
Ulmann, A1
Elomaa, I1
Sivula, A1
Kahri, A1
Puutula-Räsänen, L1
Pelkonen, R1
Ljunghall, S1
Backman, U1
Danielson, BG1
Fellström, B1
Johansson, G1
Wikström, B1
Helms, PM1
Klimiuk, PS1
Davies, M1
Adams, PH1
Mizunashi, K1
Furukawa, Y1
Abe, K1
Yoshinaga, K1
Broadus, AE1
Dominguez, M1
Bartter, FC1
Hakim, R1
Tolis, G1
Goltzman, D1
Meltzer, S1
Friedman, R1
Barilla, DE1
Pak, CY2
Coffey, RJ1
Lee, TC1
Canary, JJ1
Simeonov, S1
Maschio, G1
D'Angelo, A1
Fabris, A1
Tessitore, N1
Sartori, L1
Morbiato, F1
Malvasi, L1
Giannini, S1
Ferrari, S1
Rugiu, C1
Moss, AH1
Brickman, AS2
Massry, SG2
Coburn, JW2
Thomas, WC1
Guignard, JP1
Torrado, A1
Ruskin, B1
Diller, E1
Smith, LH1
Paloyan, E1
Farland, M1
Pickleman, JR1
Pumarino, H1
Wortsman, J1
Zacharias, A1
Litvak, J1
Alliende, I1
Armendaris, R1
Generini, G1
Koppel, MH1
Peacock, M1

Reviews

1 review available for hydrochlorothiazide and Hyperparathyroidism

ArticleYear
Symposium on renal lithiasis. Medical aspects of renal calculous disease. Treatment and prophylaxis.
    The Urologic clinics of North America, 1974, Volume: 1, Issue:2

    Topics: Acidosis, Renal Tubular; Allopurinol; Anti-Bacterial Agents; Bacterial Infections; Cystinuria; Diet;

1974

Trials

1 trial available for hydrochlorothiazide and Hyperparathyroidism

ArticleYear
changes in serum and urinary calcium during treatment with hydrochlorothiazide: studies on mechanisms.
    The Journal of clinical investigation, 1972, Volume: 51, Issue:4

    Topics: Adult; Aged; Blood Proteins; Bone Resorption; Calcium; Clinical Trials as Topic; Ergocalciferols; Ex

1972

Other Studies

21 other studies available for hydrochlorothiazide and Hyperparathyroidism

ArticleYear
Thiazide Treatment in Primary Hyperparathyroidism-A New Indication for an Old Medication?
    The Journal of clinical endocrinology and metabolism, 2017, 04-01, Volume: 102, Issue:4

    Topics: Aged; Calcium; Diuretics; Female; Humans; Hydrochlorothiazide; Hypercalcemia; Hyperparathyroidism; M

2017
[Predictive value of lithogenic risk in hypercalciuria: should 24-hour urine calcium be measured?].
    Nephrologie, 1984, Volume: 5, Issue:5

    Topics: Calcium; Creatine; Follow-Up Studies; Humans; Hydrochlorothiazide; Hyperparathyroidism; Kidney Calcu

1984
Hyperparathyroidism with hypercalciuria and urolithiasis: long-term effects of parathyroid surgery and postoperative thiazide therapy.
    World journal of surgery, 1983, Volume: 7, Issue:2

    Topics: Adenoma; Calcium; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hyperparathyroidism; Kidne

1983
Calcium metabolism in renal stone disease.
    Scandinavian journal of urology and nephrology. Supplementum, 1980, Volume: 53

    Topics: Calcium; Diagnosis, Differential; Humans; Hydrochlorothiazide; Hypercalcemia; Hyperparathyroidism; I

1980
Lithium-hydrochlorothiazide interaction?
    The American journal of psychiatry, 1982, Volume: 139, Issue:8

    Topics: Drug Interactions; Humans; Hydrochlorothiazide; Hyperparathyroidism; Lithium

1982
Primary hyperparathyroidism and thiazide diuretics.
    Postgraduate medical journal, 1981, Volume: 57, Issue:664

    Topics: Aged; Bendroflumethiazide; Calcium; Female; Humans; Hydrochlorothiazide; Hypercalcemia; Hyperparathy

1981
The modulatory effect of endogenous parathyroid hormone on the action of hydrochlorothiazide in pseudohypoparathyroidism type I.
    Calcified tissue international, 1994, Volume: 54, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Aged; Calcium; Cyclic AMP; Female; Humans; Hydrochlorothiaz

1994
Pathophysiological studies in idiopathic hypercalciuria: use of an oral calcium tolerance test to characterize distinctive hypercalciuric subgroups.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 47, Issue:4

    Topics: Adult; Calcium; Cyclic AMP; Female; Humans; Hydrochlorothiazide; Hyperparathyroidism; Intestinal Abs

1978
Severe hypercalcemia associated with hydrochlorothiazide and calcium carbonate therapy.
    Canadian Medical Association journal, 1979, Sep-08, Volume: 121, Issue:5

    Topics: Aged; Antacids; Calcium Carbonate; Diagnosis, Differential; Female; Furosemide; Hormones; Humans; Hy

1979
Pitfalls in parathyroid evaluation in patients with calcium urolithiasis.
    Urological research, 1979, Volume: 7, Issue:3

    Topics: Adult; Aged; Calcium; Female; Humans; Hydrochlorothiazide; Hyperparathyroidism; Male; Middle Aged; U

1979
The surgical treatment of primary hyperparathyroidism: a 20 year experience.
    Annals of surgery, 1977, Volume: 185, Issue:5

    Topics: Adenoma; Humans; Hydrochlorothiazide; Hypercalcemia; Hyperparathyroidism; Hyperplasia; Methods; Para

1977
Therapeutic management of bone and renal forms of hyperparathyroidism. Results of surgical and conservative treatment.
    Folia medica, 1990, Volume: 32, Issue:1

    Topics: Bone Diseases; Humans; Hydrochlorothiazide; Hyperparathyroidism; Kidney Diseases

1990
Long-term effects of low-dose thiazide and amiloride administration in recurrent renal stone formers.
    Contributions to nephrology, 1985, Volume: 49

    Topics: Adult; Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hyperparathyroidism; Kidne

1985
Renal colic, arthralgia in a hypercalcemic man.
    Hospital practice (Office ed.), 1985, Oct-30, Volume: 20, Issue:10A

    Topics: Adult; Calcium; Colic; Humans; Hydrochlorothiazide; Hypercalcemia; Hyperparathyroidism; Joint Diseas

1985
Proximal renal tubular acidosis in vitamin D deficiency rickets.
    Acta paediatrica Scandinavica, 1973, Volume: 62, Issue:5

    Topics: Acidosis, Renal Tubular; Bicarbonates; Calcium; Calcium Chloride; Female; Humans; Hydrochlorothiazid

1973
Enhancement of renal excretion of zinc by hydrochlorothiazide.
    Clinica chimica acta; international journal of clinical chemistry, 1972, Volume: 39, Issue:2

    Topics: Adolescent; Adult; Calcium; Calcium Metabolism Disorders; Copper; Female; Furosemide; Humans; Hydroc

1972
Nephrolithiasis. Current concepts in pathogenesis and management.
    Postgraduate medicine, 1972, Volume: 52, Issue:3

    Topics: Acidosis, Renal Tubular; Citrates; Cystinuria; Humans; Hydrochlorothiazide; Hydrogen-Ion Concentrati

1972
Hyperparathyroidism coexisting with hypertension and prolonged thiazide administration.
    JAMA, 1969, Nov-17, Volume: 210, Issue:7

    Topics: Adult; Antihypertensive Agents; Calcium; Chlorothiazide; Female; Humans; Hydrochlorothiazide; Hyperp

1969
[Hyperparathyroidism caused by thiazides].
    Deutsche medizinische Wochenschrift (1946), 1970, Jan-30, Volume: 95, Issue:5

    Topics: Antihypertensive Agents; Chlorothiazide; Humans; Hydrochlorothiazide; Hyperparathyroidism; Hypertens

1970
[Primary hyperparathyroidism. II. Critical evaluation of diagnostic methods].
    Revista medica de Chile, 1970, Volume: 98, Issue:11

    Topics: Adolescent; Adult; Blood Proteins; Calcium; Calcium Isotopes; Cortisone; Diagnosis, Differential; Ev

1970
The effect of hydrochlorothiazide administration on serum and urinary calcium in normal, hypoparathyroid and hyperparathyroid subjects. Studies on mechanisms.
    Israel journal of medical sciences, 1971, Volume: 7, Issue:3

    Topics: Calcium; Humans; Hydrochlorothiazide; Hyperparathyroidism; Hypoparathyroidism; Magnesium; Parathyroi

1971