hydrochlorothiazide has been researched along with Hyperkalemia in 42 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
Hyperkalemia: Abnormally high potassium concentration in the blood, most often due to defective renal excretion. It is characterized clinically by electrocardiographic abnormalities (elevated T waves and depressed P waves, and eventually by atrial asystole). In severe cases, weakness and flaccid paralysis may occur. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this case report, significant hyperkalemia and hyponatremia related to telmisartan/hydrochlorothiazide use in a diabetic patient has been presented." | 7.76 | Significant hyperkalemia and hyponatremia secondary to telmisartan/hydrochlorothiazide treatment. ( Cakir, M, 2010) |
| " Here we report the results of a pre-planned 6-month interim analysis of a long-term, open-label study examining the safety, tolerability and efficacy of the aliskiren/valsartan 300/320-mg combination in patients with hypertension." | 7.74 | Long-term safety, tolerability and efficacy of aliskiren in combination with valsartan in patients with hypertension: a 6-month interim analysis. ( Chrysant, SG; Dattani, D; Hoppe, UC; Hsu, H; Murray, AV; Patel, S; Zhang, J, 2008) |
| "Horses with hyperkalaemic periodic paralysis were challenged with an oral dose of potassium chloride, and the prophylactic efficacy of phenytoin, acetazolamide and hydrochlorothiazide was evaluated, with at least three weeks separating the trials of each drug." | 7.69 | Prophylactic efficacy of phenytoin, acetazolamide and hydrochlorothiazide in horses with hyperkalaemic periodic paralysis. ( Beech, J; Lindborg, S, 1995) |
| " Each had amiloride HCl/hydrochlorothiazide added to their therapeutic regimen 8 to 18 days before presenting to our ED with hyperkalemia." | 7.69 | Rapid life-threatening hyperkalemia after addition of amiloride HCl/hydrochlorothiazide to angiotensin-converting enzyme inhibitor therapy. ( Bullard, MJ; Chen, JC; Chiu, TF; Liaw, SJ; Ng, CJ, 1997) |
| "We investigated the effectiveness of tocainide and hydrochlorothiazide on muscular symptoms in a patient with paramyotonia congenita and episodic attacks of hyperkalemic paralysis." | 7.66 | Different effectiveness of tocainide and hydrochlorothiazide in paramyotonia congenita with hyperkalemic episodic paralysis. ( Böhlen, R; Ricker, K; Rohkamm, R, 1983) |
| "Simultaneous administration of indomethacin and Moduretic (Merck Sharp & Dohme, USA, 5 mg of amiloride HCl, 50 mg hydrochlorothiazide) to a 78-yr-old patient resulted in severe hyperkalemia twice." | 7.66 | Indomethacin- and Moduretic--induced hyperkalemia. ( Mor, R; Pitlik, S; Rosenfeld, JB, 1983) |
| " The dosage of cation exchange resins was decreased, oral fluids were tolerated, and the patient's general condition improved." | 5.29 | Effect of hydrochlorothiazide in pseudohypoaldosteronism with hypercalciuria and severe hyperkalemia. ( Rosa, FC; Stone, RC; Vale, P, 1996) |
| "Hyperkalemia is known to occur with increased frequency in the patient with diabetes mellitus and in the elderly when agents that interfere with renal potassium excretion are employed, but the precise frequency has not been established." | 5.28 | Hyperkalemia in diabetes mellitus. Effect of a triamterene-hydrochlorothiazide combination. ( Hollenberg, NK; Mickiewicz, C, 1989) |
| " In this case report, significant hyperkalemia and hyponatremia related to telmisartan/hydrochlorothiazide use in a diabetic patient has been presented." | 3.76 | Significant hyperkalemia and hyponatremia secondary to telmisartan/hydrochlorothiazide treatment. ( Cakir, M, 2010) |
| " Here we report the results of a pre-planned 6-month interim analysis of a long-term, open-label study examining the safety, tolerability and efficacy of the aliskiren/valsartan 300/320-mg combination in patients with hypertension." | 3.74 | Long-term safety, tolerability and efficacy of aliskiren in combination with valsartan in patients with hypertension: a 6-month interim analysis. ( Chrysant, SG; Dattani, D; Hoppe, UC; Hsu, H; Murray, AV; Patel, S; Zhang, J, 2008) |
| " To control hypertension and chronic heart failure he had been treated with 5 mg ramipril and 12." | 3.73 | [A patient with severe hyperkalaemia -- an emergency after RALES]. ( Daul, A; Nürnberger, J; Philipp, T, 2005) |
| "Horses with hyperkalaemic periodic paralysis were challenged with an oral dose of potassium chloride, and the prophylactic efficacy of phenytoin, acetazolamide and hydrochlorothiazide was evaluated, with at least three weeks separating the trials of each drug." | 3.69 | Prophylactic efficacy of phenytoin, acetazolamide and hydrochlorothiazide in horses with hyperkalaemic periodic paralysis. ( Beech, J; Lindborg, S, 1995) |
| " Each had amiloride HCl/hydrochlorothiazide added to their therapeutic regimen 8 to 18 days before presenting to our ED with hyperkalemia." | 3.69 | Rapid life-threatening hyperkalemia after addition of amiloride HCl/hydrochlorothiazide to angiotensin-converting enzyme inhibitor therapy. ( Bullard, MJ; Chen, JC; Chiu, TF; Liaw, SJ; Ng, CJ, 1997) |
| "We investigated the effectiveness of tocainide and hydrochlorothiazide on muscular symptoms in a patient with paramyotonia congenita and episodic attacks of hyperkalemic paralysis." | 3.66 | Different effectiveness of tocainide and hydrochlorothiazide in paramyotonia congenita with hyperkalemic episodic paralysis. ( Böhlen, R; Ricker, K; Rohkamm, R, 1983) |
| "Simultaneous administration of indomethacin and Moduretic (Merck Sharp & Dohme, USA, 5 mg of amiloride HCl, 50 mg hydrochlorothiazide) to a 78-yr-old patient resulted in severe hyperkalemia twice." | 3.66 | Indomethacin- and Moduretic--induced hyperkalemia. ( Mor, R; Pitlik, S; Rosenfeld, JB, 1983) |
| "A patient who developed significant metabolic acidosis and severe hyperkalaemia while taking Moduretic (amiloride and hydrochlorothiazide) is reported." | 3.66 | Moduretic-induced metabolic acidosis and hyperkalaemia. ( Lye, MD; Wan, HH, 1980) |
| "We describe a patient with diabetic nephropathy and proteinuria who developed a remarkable hyperkalaemia on treatment with an angiotensin-receptor blocker." | 1.34 | Treating proteinuria in a diabetic patient despite hyperkalaemia due to hyporeninaemic hypoaldosteronism. ( Bolk, JH; Ijpelaar, DH; van Nieuwkoop, C, 2007) |
| "Type II pseudohypoaldosteronism is a rare tubulopathy defined by abnormal renal potassium excretion." | 1.29 | [Dwarfism, arterial hypertension and hyperkalemic acidosis corrected with thiazides. A case of type II pseudohypoaldosteronism]. ( Brusquet, Y; Cornus, P; Cournelle, MA; Frayssinet, R; Poujol, A; Rimet, Y; Zarrouk, F, 1993) |
| " The dosage of cation exchange resins was decreased, oral fluids were tolerated, and the patient's general condition improved." | 1.29 | Effect of hydrochlorothiazide in pseudohypoaldosteronism with hypercalciuria and severe hyperkalemia. ( Rosa, FC; Stone, RC; Vale, P, 1996) |
| "Hyperkalemia is known to occur with increased frequency in the patient with diabetes mellitus and in the elderly when agents that interfere with renal potassium excretion are employed, but the precise frequency has not been established." | 1.28 | Hyperkalemia in diabetes mellitus. Effect of a triamterene-hydrochlorothiazide combination. ( Hollenberg, NK; Mickiewicz, C, 1989) |
| "The acidosis and hyperkalemia are corrected by hydrochlorothiazide." | 1.27 | Familiar hyperkalaemic acidosis. ( Amundson, D; Hsueh, WA; Licht, JH; Lombardo, JV, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (61.90) | 18.7374 |
| 1990's | 9 (21.43) | 18.2507 |
| 2000's | 4 (9.52) | 29.6817 |
| 2010's | 2 (4.76) | 24.3611 |
| 2020's | 1 (2.38) | 2.80 |
| Authors | Studies |
|---|---|
| Qin, L | 1 |
| Zhang, N | 1 |
| Ishigami, J | 1 |
| Miller, ER | 1 |
| Pfister, M | 1 |
| Moran, AE | 1 |
| Cox, E | 1 |
| Hollander, R | 1 |
| Mortier, G | 1 |
| van Hoeck, K | 1 |
| Cakir, M | 1 |
| ALLSOP, JL | 1 |
| GOULSTON, K | 1 |
| JOHNSTON, C | 1 |
| KELLY, D | 1 |
| RAIL, L | 1 |
| PEARSON, CM | 1 |
| SAMAHA, FJ | 1 |
| ILIESCU, CC | 1 |
| KLEINERMAN, L | 1 |
| Weinstein, AM | 1 |
| Nürnberger, J | 1 |
| Daul, A | 1 |
| Philipp, T | 1 |
| van Nieuwkoop, C | 1 |
| Ijpelaar, DH | 1 |
| Bolk, JH | 1 |
| Chrysant, SG | 1 |
| Murray, AV | 1 |
| Hoppe, UC | 1 |
| Dattani, D | 1 |
| Patel, S | 1 |
| Hsu, H | 1 |
| Zhang, J | 1 |
| Abakumov, GG | 1 |
| Kots, IaI | 1 |
| Jaffey, L | 1 |
| Martin, A | 1 |
| Ricker, K | 1 |
| Böhlen, R | 1 |
| Rohkamm, R | 1 |
| Mor, R | 1 |
| Pitlik, S | 1 |
| Rosenfeld, JB | 1 |
| Garsdal, P | 1 |
| Bjaeldager, P | 1 |
| Svendsen, TL | 1 |
| Kampmann, JP | 1 |
| Wan, HH | 1 |
| Lye, MD | 1 |
| Poujol, A | 1 |
| Rimet, Y | 1 |
| Cournelle, MA | 1 |
| Cornus, P | 1 |
| Frayssinet, R | 1 |
| Zarrouk, F | 1 |
| Brusquet, Y | 1 |
| Freeman, SJ | 1 |
| Fale, AD | 1 |
| Beech, J | 1 |
| Lindborg, S | 1 |
| Stone, RC | 1 |
| Vale, P | 1 |
| Rosa, FC | 1 |
| Chiu, TF | 1 |
| Bullard, MJ | 1 |
| Chen, JC | 1 |
| Liaw, SJ | 1 |
| Ng, CJ | 1 |
| Stepan, VM | 1 |
| Hammer, HF | 1 |
| Krejs, GJ | 1 |
| Iranzo, A | 1 |
| Santamaria, J | 1 |
| Hollenberg, NK | 3 |
| DeFronzo, RA | 1 |
| Goldberg, M | 1 |
| Cooke, CR | 1 |
| Barker, C | 1 |
| Grossman, RA | 1 |
| Agus, ZS | 1 |
| Whiting, GF | 1 |
| McLaran, CJ | 1 |
| Bochner, F | 1 |
| Heim, J | 1 |
| Dewailly, P | 1 |
| Jaillard, J | 1 |
| Petersen, AG | 1 |
| Isenring, P | 1 |
| Lebel, M | 1 |
| Grose, JH | 1 |
| Szylman, P | 1 |
| Wolach, B | 1 |
| Winaver, J | 1 |
| Panett, R | 1 |
| Cohen, P | 1 |
| Shenkman, L | 1 |
| Better, OS | 1 |
| Pasman, JW | 1 |
| Gabreëls, FJ | 1 |
| Semmekrot, B | 1 |
| Renier, WO | 1 |
| Monnens, LA | 1 |
| Mickiewicz, C | 1 |
| Blaser, KU | 1 |
| Lämmle, B | 1 |
| Bannon, JA | 1 |
| Houston, MC | 1 |
| Johnston, PE | 1 |
| Greenberg, A | 1 |
| Licht, JH | 1 |
| Amundson, D | 1 |
| Hsueh, WA | 1 |
| Lombardo, JV | 1 |
| Weinstein, SF | 1 |
| Allan, DM | 1 |
| Mendoza, SA | 1 |
| Szende, L | 1 |
| Radó, JP | 1 |
| Takó, J | 1 |
| Dévényi, I | 1 |
| Yamada, S | 1 |
| Reynolds, TB | 1 |
| Paterson, JW | 1 |
| Dollery, CT | 1 |
| Haslam, RM | 1 |
2 reviews available for hydrochlorothiazide and Hyperkalemia
| Article | Year |
|---|---|
Dyskalemia risk associated with fixed-dose anti-hypertensive medication combinations.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; | 2022 |
Essential hypertension: new insights and controversies in treatment with diuretics.
Topics: Amiloride; Antihypertensive Agents; Blood Pressure; Coronary Disease; Diuretics; Dose-Response Relat | 1986 |
3 trials available for hydrochlorothiazide and Hyperkalemia
| Article | Year |
|---|---|
The PACT study: post-marketing surveillance in 47,465 patients treated with Maxzide (triamterene/hydrochlorothiazide). An interim report.
Topics: Age Factors; Antihypertensive Agents; Clinical Trials as Topic; Drug Combinations; Female; Humans; H | 1986 |
Amiloride (MK-870), a new antikaluretic diuretic. Comparison to other antikaluretic diuretics in patients with liver disease and ascites.
Topics: Acid-Base Equilibrium; Amidines; Ascites; Autopsy; Carcinoma; Diuretics; Ethacrynic Acid; Humans; Hy | 1970 |
Amiloride hydrochloride in hypertensive patients.
Topics: Bicarbonates; Blood Pressure; Chlorides; Depression, Chemical; Diuretics; Drug Synergism; Guanidines | 1968 |
37 other studies available for hydrochlorothiazide and Hyperkalemia
| Article | Year |
|---|---|
Hyperkalemia in young children: blood pressure checked?
Topics: Child; Diuretics; Female; Humans; Hydrochlorothiazide; Hyperkalemia; Hypertension; Incidental Findin | 2016 |
Significant hyperkalemia and hyponatremia secondary to telmisartan/hydrochlorothiazide treatment.
Topics: Aged; Benzimidazoles; Benzoates; Blood Pressure; Drug Combinations; Humans; Hydrochlorothiazide; Hyp | 2010 |
FAMILIAL HYPERKALAEMIC PERIODIC PARALYSIS.
Topics: Acetazolamide; Adolescent; Blood Chemical Analysis; Calcium; Electrocardiography; Electromyography; | 1964 |
THE PERIODIC PARALYSES: DIFFERENTIAL FEATURES AND PATHOLOGICAL OBSERVATIONS IN PERMANENT MYOPATHIC WEAKNESS.
Topics: Acetazolamide; Drug Therapy; Epinephrine; Humans; Hydrochlorothiazide; Hydrocortisone; Hyperkalemia; | 1964 |
HYPERKALEMIC PERIODIC PARALYSIS. A GENETIC STUDY, CLINICAL OBSERVATIONS, AND REPORT OF A NEW METHOD OF THERAPY.
Topics: Acetazolamide; Amphetamine; Amphetamines; Chlorothiazide; Electromyography; Genetics, Medical; Human | 1965 |
THE EFFECT OF REDUCTION OF BLOOD POTASSIUM LEVEL IN THE TREATMENT OF A-V BLOCK AND IN THE PREVENTION OF ADAMS-STOKES ATTACKS.
Topics: Acetazolamide; Adams-Stokes Syndrome; Adolescent; Adrenal Cortex Hormones; Chlorothiazide; Drug Ther | 1965 |
A mathematical model of rat distal convoluted tubule. II. Potassium secretion along the connecting segment.
Topics: Acid-Base Equilibrium; Algorithms; Alkalosis; Animals; Cell Membrane Permeability; Diuretics; Electr | 2005 |
[A patient with severe hyperkalaemia -- an emergency after RALES].
Topics: Acute Kidney Injury; Adrenergic beta-Agonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin- | 2005 |
Treating proteinuria in a diabetic patient despite hyperkalaemia due to hyporeninaemic hypoaldosteronism.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Diabetes Mellitus, Type 2; Diabet | 2007 |
Long-term safety, tolerability and efficacy of aliskiren in combination with valsartan in patients with hypertension: a 6-month interim analysis.
Topics: Aged; Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Ant | 2008 |
[Hyperkalemia in total atrioventricular block and its change under the effect of treatment].
Topics: Aged; Heart Block; Humans; Hydrochlorothiazide; Hyperkalemia; Male; Prednisolone | 1966 |
Malignant hyperkalaemia after amiloride/hydrochlorothiazide treatment.
Topics: Aged; Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hyperkalemia; Potassium; Py | 1981 |
Different effectiveness of tocainide and hydrochlorothiazide in paramyotonia congenita with hyperkalemic episodic paralysis.
Topics: Adult; Humans; Hydrochlorothiazide; Hyperkalemia; Hypothermia, Induced; Lidocaine; Male; Myotonia Co | 1983 |
Indomethacin- and Moduretic--induced hyperkalemia.
Topics: Aged; Amiloride; Diabetes Complications; Diabetes Mellitus; Drug Combinations; Drug Interactions; Fe | 1983 |
[Severe hyperkalemia during treatment with Moduretic].
Topics: Aged; Amiloride; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hyperkalemia; Pyrazines | 1982 |
Moduretic-induced metabolic acidosis and hyperkalaemia.
Topics: Acidosis; Aged; Amiloride; Drug Combinations; Humans; Hydrochlorothiazide; Hyperkalemia; Male; Pyraz | 1980 |
[Dwarfism, arterial hypertension and hyperkalemic acidosis corrected with thiazides. A case of type II pseudohypoaldosteronism].
Topics: Acidosis, Renal Tubular; Child; Dwarfism; Female; Humans; Hydrochlorothiazide; Hyperkalemia; Hyperte | 1993 |
Muscular paralysis and ventilatory failure caused by hyperkalaemia.
Topics: Aged; Amiloride; Drug Combinations; Humans; Hydrochlorothiazide; Hyperkalemia; Male; Paralysis; Resp | 1993 |
Prophylactic efficacy of phenytoin, acetazolamide and hydrochlorothiazide in horses with hyperkalaemic periodic paralysis.
Topics: Acetazolamide; Animals; Diuretics; Horse Diseases; Horses; Hydrochlorothiazide; Hyperkalemia; Male; | 1995 |
Effect of hydrochlorothiazide in pseudohypoaldosteronism with hypercalciuria and severe hyperkalemia.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcium; Diuretics; Female; Furosemide; Humans; Hydrochloro | 1996 |
Rapid life-threatening hyperkalemia after addition of amiloride HCl/hydrochlorothiazide to angiotensin-converting enzyme inhibitor therapy.
Topics: Aged; Aged, 80 and over; Amiloride; Angiotensin-Converting Enzyme Inhibitors; Diuretics; Drug Intera | 1997 |
Hyperkalaemia and diarrhoea in a patient with surreptitious ingestion of potassium sparing diuretics.
Topics: Chronic Disease; Diarrhea; Diuretics; Female; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hyper | 1997 |
Hyperkalemic periodic paralysis associated with multiple sleep onset REM periods.
Topics: Adult; Diuretics; Humans; Hydrochlorothiazide; Hyperkalemia; Male; Paralysis; Periodicity; Potassium | 1999 |
Preventing hypokalemia
Topics: Angiotensin-Converting Enzyme Inhibitors; Diabetes Complications; Diuretics; Drug Interactions; Huma | 1987 |
Investigations into the mechanisms of hyperkalemia following renal transplantation.
Topics: Adolescent; Adult; Aldosterone; Female; Humans; Hydrochlorothiazide; Hyperkalemia; Kidney Transplant | 1977 |
Severe hyperkalaemia with Moduretic.
Topics: Aged; Amiloride; Arrhythmias, Cardiac; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hyper | 1979 |
[Hyperkalemia caused by hyporeninism: role of the hydrochlorothiazide-amiloride combination].
Topics: Aged; Aldosterone; Amiloride; Diabetes Complications; Female; Heart Failure; Humans; Hydrochlorothia | 1977 |
Letter: Dyazide and hyperkalemia.
Topics: Drug Combinations; Humans; Hydrochlorothiazide; Hyperkalemia; Triamterene | 1976 |
Endocrine sodium and volume regulation in familial hyperkalemia with hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Atrial Natriuretic Factor; Family; Female; Humans; Hydrochloroth | 1992 |
Nonazotemic hyperkalemia with renal and extrarenal defects in potassium transport: association with high levels of digoxin-like immunoreactive factor.
Topics: Acid-Base Equilibrium; Adult; Biological Transport; Blood Proteins; Cardenolides; Digoxin; Electroly | 1990 |
Hyperkalemic periodic paralysis in Gordon's syndrome: a possible defect in atrial natriuretic peptide function.
Topics: Adolescent; Atrial Natriuretic Factor; Humans; Hydrochlorothiazide; Hyperkalemia; Hypertension; Male | 1989 |
Hyperkalemia in diabetes mellitus. Effect of a triamterene-hydrochlorothiazide combination.
Topics: Diabetes Complications; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hyperkalemia; Hypert | 1989 |
[Acute hyperkalemia and non-oliguric kidney failure during treatment with indomethacin, allopurinol, nifedipine, hydrochlorothiazide/amiloride, trimethoprim/sulfamethoxazole and acetylsalicylic acid].
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Allopurinol; Amiloride; Aspirin; Drug Combinations; Dr | 1988 |
What's new in diuretic therapy.
Topics: Acetazolamide; Acid-Base Imbalance; Biological Transport; Diuretics; Drug Resistance; Ethacrynic Aci | 1986 |
Familiar hyperkalaemic acidosis.
Topics: Acid-Base Equilibrium; Acidosis, Renal Tubular; Adult; Aldosterone; Desoxycorticosterone; Diet, Sodi | 1985 |
Hyperkalemia, acidosis, and short stature associated with a defect in renal potassium excretion.
Topics: Acidosis; Administration, Oral; Ammonium Chloride; Bicarbonates; Blood; Body Height; Body Weight; Ca | 1974 |
Hyperkalemia and coma associated with renal tubular acidosis in an old patient with refractory edema due to the nephrotic syndrome: furosemide-bicarbonate therapy.
Topics: Acidosis, Renal Tubular; Adrenal Cortex Hormones; Aged; Aldosterone; Bicarbonates; Coma; Edema; Furo | 1972 |