hydrochlorothiazide has been researched along with Hypercalciuria in 19 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
Hypercalciuria: Excretion of abnormally high level of CALCIUM in the URINE, greater than 4 mg/kg/day.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Calcium oxalate (Ca-Ox) is the most common stone composition and one of the most common 24-h urine anomalies is hypercalciuria." | 9.41 | Potassium citrate vs. hydrochlorothiazide to reduce urinary calcium excretion in calcium oxalate stone patients with hypercalciuria: a prospective randomized study. ( Gökce, Mİ; Solak, V; Yaman, Ö, 2021) |
| "The aim of this study was to evaluate the role of hydrochlorothiazide in pediatric calculus formers with hypercalciuria and define possible factors affecting response to treatment." | 9.15 | Role of high-dose hydrochlorothiazide in idiopathic hypercalciuric urolithiasis of childhood. ( Naseri, M; Sadeghi, R, 2011) |
| "Calcium oxalate (Ca-Ox) is the most common stone composition and one of the most common 24-h urine anomalies is hypercalciuria." | 5.41 | Potassium citrate vs. hydrochlorothiazide to reduce urinary calcium excretion in calcium oxalate stone patients with hypercalciuria: a prospective randomized study. ( Gökce, Mİ; Solak, V; Yaman, Ö, 2021) |
| "The aim of this study was to evaluate the role of hydrochlorothiazide in pediatric calculus formers with hypercalciuria and define possible factors affecting response to treatment." | 5.15 | Role of high-dose hydrochlorothiazide in idiopathic hypercalciuric urolithiasis of childhood. ( Naseri, M; Sadeghi, R, 2011) |
| "Hydrochlorothiazide (HCT) is applied in the therapy of familial hypomagnesaemia with hypercalciuria and nephrocalcinosis (FHHNC) caused by claudin-16 (CLDN16) mutation." | 5.12 | Hydrochlorothiazide in CLDN16 mutation. ( Dötsch, J; Gravou-Apostolatou, C; Konrad, M; Plank, C; Rascher, W; Stöhr, W; Zimmermann, B, 2006) |
| "To evaluate the therapeutic effect of hydrochlorothiazide in idiopathic renal hypercalciuria." | 3.77 | Low-dose thiazide diuretics in children with idiopathic renal hypercalciuria. ( Choi, JN; Lee, JS; Shin, JI, 2011) |
| "Thiazide doses equivalent to 1 to 2 mg/kg/d of hydrochlorothiazide (HCTZ) have been proposed to correct hypercalciuria and prevent kidney failure in patients with Dent disease." | 3.74 | Effect of hydrochlorothiazide on urinary calcium excretion in dent disease: an uncontrolled trial. ( Azizi, M; Baudouin, V; Blanchard, A; Boudailliez, B; Charbit, M; Deschesnes, G; Ezzhair, N; Loirat, C; Macher, MA; Mogenet, A; Niaudet, P; Peyrard, S; Vargas-Poussou, R, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.53) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (26.32) | 29.6817 |
| 2010's | 9 (47.37) | 24.3611 |
| 2020's | 3 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| Verploegen, MFA | 1 |
| Nijenhuis, T | 1 |
| Solak, V | 1 |
| Gökce, Mİ | 1 |
| Yaman, Ö | 1 |
| Ji, Y | 1 |
| Kang, C | 1 |
| Chen, J | 1 |
| Zhang, L | 1 |
| Song, L | 1 |
| Maalouf, NM | 1 |
| Ábalos-Medina, GM | 1 |
| Fernández Rodríguez, I | 1 |
| del Mar Almagro Ratia, M | 1 |
| Fuentes Ellauri, MA | 1 |
| Blanchard, A | 1 |
| Vargas-Poussou, R | 1 |
| Peyrard, S | 1 |
| Mogenet, A | 1 |
| Baudouin, V | 1 |
| Boudailliez, B | 1 |
| Charbit, M | 1 |
| Deschesnes, G | 1 |
| Ezzhair, N | 1 |
| Loirat, C | 1 |
| Macher, MA | 1 |
| Niaudet, P | 1 |
| Azizi, M | 1 |
| Jang, HR | 2 |
| Kim, S | 2 |
| Heo, NJ | 2 |
| Lee, JH | 2 |
| Kim, HS | 2 |
| Nielsen, S | 1 |
| Jeon, US | 1 |
| Oh, YK | 2 |
| Na, KY | 2 |
| Joo, KW | 2 |
| Han, JS | 2 |
| Berg, W | 1 |
| Bechler, R | 1 |
| Haas, C | 1 |
| Laube, N | 1 |
| Lee, JW | 1 |
| Jung, JY | 1 |
| Choi, JN | 1 |
| Lee, JS | 1 |
| Shin, JI | 2 |
| Naseri, M | 1 |
| Sadeghi, R | 1 |
| Park, SJ | 1 |
| Kim, JH | 1 |
| Yousefi, P | 1 |
| Firouzifar, M | 1 |
| Cyrus, A | 1 |
| Zhang, J | 1 |
| Xia, ZK | 1 |
| Arrabal-Polo, MA | 1 |
| Arias-Santiago, S | 1 |
| de Haro-Muñoz, T | 1 |
| Lopez-Ruiz, A | 1 |
| Orgaz-Molina, J | 1 |
| Gonzalez-Torres, S | 1 |
| Zuluaga-Gomez, A | 1 |
| Arrabal-Martin, M | 1 |
| FANCONI, A | 1 |
| NASSIM, JR | 1 |
| HIGGINS, BA | 1 |
| Zimmermann, B | 1 |
| Plank, C | 1 |
| Konrad, M | 1 |
| Stöhr, W | 1 |
| Gravou-Apostolatou, C | 1 |
| Rascher, W | 1 |
| Dötsch, J | 1 |
| Valcourt, EE | 1 |
| Fleming, NA | 1 |
| Weiler, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacodynamic Evaluation of the ANTICALCIURIC Effect of Hydrochlorothiazide in Dent's Disease[NCT00638482] | Phase 2/Phase 3 | 10 participants (Actual) | Interventional | 2003-07-31 | Terminated (stopped due to terminated) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for hydrochlorothiazide and Hypercalciuria
| Article | Year |
|---|---|
[Clinical characteristics and molecular genetics of Dent's disease: an update].
Topics: Animals; Child; Child, Preschool; Chloride Channels; Dent Disease; Diuretics; Humans; Hydrochlorothi | 2012 |
4 trials available for hydrochlorothiazide and Hypercalciuria
| Article | Year |
|---|---|
Potassium citrate vs. hydrochlorothiazide to reduce urinary calcium excretion in calcium oxalate stone patients with hypercalciuria: a prospective randomized study.
Topics: Adult; Calcium; Calcium Oxalate; Diuretics; Female; Humans; Hydrochlorothiazide; Hypercalciuria; Kid | 2021 |
Role of high-dose hydrochlorothiazide in idiopathic hypercalciuric urolithiasis of childhood.
Topics: Administration, Oral; Calcium; Child, Preschool; Diuretics; Dose-Response Relationship, Drug; Female | 2011 |
Does hydrochlorothiazide prevent recurrent urinary tract infection in children with idiopathic hypercalciuria?
Topics: Child; Child, Preschool; Diuretics; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypercal | 2013 |
Hydrochlorothiazide in CLDN16 mutation.
Topics: Adolescent; Adult; Calcium; Child; Child, Preschool; Claudins; Creatinine; Dose-Response Relationshi | 2006 |
14 other studies available for hydrochlorothiazide and Hypercalciuria
| Article | Year |
|---|---|
[Thiazides to prevent recurrence of kidney stones: is hydrochlorothiazide still indicated?]
Topics: Calcium; Humans; Hydrochlorothiazide; Hypercalciuria; Kidney Calculi; Thiazides | 2023 |
Identification of p.Arg205Cys in CASR in an autosomal dominant hypocalcaemia type 1 pedigree: A case report.
Topics: Calcitriol; Calcium; DNA Mutational Analysis; Drug Therapy, Combination; Female; Genetic Testing; He | 2021 |
24-Hour Urine Calcium in the Evaluation and Management of Nephrolithiasis.
Topics: Adult; Calcium; Diuretics; Humans; Hydrochlorothiazide; Hypercalciuria; Male; Nephrolithiasis | 2017 |
[Mineral and bone disorder associated with Cacchi-Ricci disease].
Topics: Adult; Alendronate; Bone Density Conservation Agents; Bone Remodeling; Calcifediol; Calcium; Drug Th | 2014 |
Effect of hydrochlorothiazide on urinary calcium excretion in dent disease: an uncontrolled trial.
Topics: Adolescent; Calcium; Child; Diuretics; Humans; Hydrochlorothiazide; Hypercalciuria; Hypophosphatemia | 2008 |
Effects of thiazide on the expression of TRPV5, calbindin-D28K, and sodium transporters in hypercalciuric rats.
Topics: Animals; Biological Transport; Calbindin 1; Calbindins; Calcium; Calcium Channels; Hydrochlorothiazi | 2009 |
Relevance of the BONN Risk Index for metabolic monitoring of patients with calcium oxalate urolithiasis: a clinical application study of the Urolizer.
Topics: Adult; Aged; Calcium Oxalate; Citric Acid; Crystallization; Female; Humans; Hydrochlorothiazide; Hyd | 2009 |
High dose vitamin D3 attenuates the hypocalciuric effect of thiazide in hypercalciuric rats.
Topics: Animals; Calcium; Calcium Channels; Cholecalciferol; Hydrochlorothiazide; Hypercalciuria; Rats; Rats | 2010 |
Low-dose thiazide diuretics in children with idiopathic renal hypercalciuria.
Topics: Child; Diuretics; Female; Hematuria; Humans; Hydrochlorothiazide; Hypercalciuria; Kidney Diseases; M | 2011 |
Low-dose or high-dose hydrochlorothiazide in idiopathic hypercalciuria among children? Re: role of high-dose hydrochlorothiazide in idiopathic hypercalciuric urolithiasis of childhood.
Topics: Calcium; Diuretics; Female; Humans; Hydrochlorothiazide; Hypercalciuria; Male; Urolithiasis | 2012 |
Effects of aminobisphosphonates and thiazides in patients with osteopenia/osteoporosis, hypercalciuria, and recurring renal calcium lithiasis.
Topics: Alendronate; Bone Density; Bone Density Conservation Agents; Bone Diseases, Metabolic; Calcium; Fema | 2013 |
[IDIOPATHIC HYPERCALCIURIA IN CHILDHOOD].
Topics: Body Fluids; Calcium Metabolism Disorders; Child; Humans; Hydrochlorothiazide; Hypercalciuria; Kidne | 1963 |
CONTROL OF IDIOPATHIC HYPERCALCIURIA.
Topics: Bendroflumethiazide; Bicarbonates; Blood Chemical Analysis; Calcium; Calcium Metabolism Disorders; C | 1965 |
Hypercalciuria as a cause of genital bleeding in a 6-year-old girl.
Topics: Child; Diuretics; Female; Hematuria; Humans; Hydrochlorothiazide; Hypercalciuria; Treatment Outcome; | 2006 |