Page last updated: 2024-10-28

hydrochlorothiazide and Graves Disease

hydrochlorothiazide has been researched along with Graves Disease in 2 studies

Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.

Graves Disease: A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
WATTS, WE1
Guy, JR1
Fagien, S1
Donovan, JP1
Rubin, ML1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of Efficacy and Safety of Intravenous Pulsed Methylprednisolone and Oral Methotrexate Versus Intravenous Pulsed Methylprednisolone and Oral Placebo in the Treatment of Active Moderate and Severe Thyroid Eye Disease - a Prospective, Randomized, [NCT00348413]80 participants (Anticipated)Interventional2003-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

2 other studies available for hydrochlorothiazide and Graves Disease

ArticleYear
LOCALIZED MYXEDEMA--GENERALIZED IN SCARS.
    Northwest medicine, 1964, Volume: 63

    Topics: Cicatrix; Dexamethasone; Diuretics; Exophthalmos; Goiter; Graves Disease; Humans; Hydrochlorothiazid

1964
Methylprednisolone pulse therapy in severe dysthyroid optic neuropathy.
    Ophthalmology, 1989, Volume: 96, Issue:7

    Topics: Adult; Female; Graves Disease; Humans; Hydrochlorothiazide; Hypertension; Injections, Intravenous; M

1989