hydrochlorothiazide has been researched along with Gout in 21 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
Gout: Metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of URIC ACID calculi.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study assessed the risk of new-onset gout following prescribing of hydrochlorothiazide (HCTZ) compared with chlorthalidone (CTD)." | 7.80 | Comparison of new-onset gout in adults prescribed chlorthalidone vs. hydrochlorothiazide for hypertension. ( Nair, KV; Saseen, JJ; Wilson, L, 2014) |
| " Serum uric acid levels may rise slightly, but no clinical gout was seen in this study." | 7.64 | TREATMENT OF CONGESTIVE HEART FAILURE WITH TRIAMTERENE. ( FRIEDMAN, R; SCHUCHER, R; WENER, J, 1965) |
| " Better understanding of the transporters URAT1 and ABCG2 in particular would appear to provide opportunities for more selective, better tolerated agents to increase the renal clearance of uric acid and thereby control hyperuricemia." | 4.90 | Uricosuric drugs: the once and future therapy for hyperuricemia? ( Bach, MH; Simkin, PA, 2014) |
| "This study assessed the risk of new-onset gout following prescribing of hydrochlorothiazide (HCTZ) compared with chlorthalidone (CTD)." | 3.80 | Comparison of new-onset gout in adults prescribed chlorthalidone vs. hydrochlorothiazide for hypertension. ( Nair, KV; Saseen, JJ; Wilson, L, 2014) |
| "Forty-nine patients with gout, many with hypertension and/or renal calculi, were given hydrochlorothiazide, furosemide, or ticrynafen." | 3.66 | Effects of diuretics on urate and calcium excretion. ( Berger, L; Kaung, C; Sarkozi, L; Yü, T, 1981) |
| " The drug is particularly useful in patients with chronic gouty arthritis and tophi, either refractory or allergic to probenecid, sulfinpyrazone, or allopurinol." | 3.65 | Pharmacokinetic and clinical studies of a new uricosuric agent - benzbromarone. ( Yu, TF, 1976) |
| " Serum uric acid levels may rise slightly, but no clinical gout was seen in this study." | 3.64 | TREATMENT OF CONGESTIVE HEART FAILURE WITH TRIAMTERENE. ( FRIEDMAN, R; SCHUCHER, R; WENER, J, 1965) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (71.43) | 18.7374 |
| 1990's | 2 (9.52) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (19.05) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bach, MH | 1 |
| Simkin, PA | 1 |
| Wilson, L | 1 |
| Nair, KV | 1 |
| Saseen, JJ | 1 |
| Handler, J | 1 |
| Messerli, FH | 1 |
| Makani, H | 1 |
| Halpern, D | 1 |
| MASON, RM | 1 |
| REUTTER, F | 1 |
| SCHAUB, F | 1 |
| GELFAND, ML | 1 |
| GARREN, MG | 1 |
| ROWAN, RL | 1 |
| ANICHINI, M | 1 |
| GARGANO, N | 1 |
| BARTORELLI, C | 1 |
| WENER, J | 1 |
| SCHUCHER, R | 1 |
| FRIEDMAN, R | 1 |
| MASONI, A | 1 |
| TOMASI, AM | 1 |
| ANTONIOLI, G | 1 |
| Bufalari, A | 1 |
| Meloni, G | 1 |
| Yü, T | 1 |
| Berger, L | 1 |
| Sarkozi, L | 1 |
| Kaung, C | 1 |
| Peterseim, U | 1 |
| von Gizycki-Nienhaus, B | 1 |
| Schattenkirchner, M | 1 |
| Meurer, M | 1 |
| Yu, TF | 1 |
| Fletcher, AE | 1 |
| Maroko, PR | 1 |
| McDevitt, JT | 1 |
| Fox, MJ | 1 |
| Silber, SA | 1 |
| Young, MD | 1 |
| Beg, M | 1 |
| Rockhold, FW | 1 |
| Free, SM | 1 |
| Herron, JR | 1 |
| Gray, JM | 1 |
| Ravera, M | 1 |
| Spaziante, B | 1 |
| Hutchison, JC | 1 |
| Wilkinson, WH | 1 |
| McMahon, FG | 1 |
| Cagli, V | 1 |
| Ruotolo, V | 1 |
| Bossini, A | 1 |
| Bologna, E | 1 |
| Lavicka, J | 1 |
| Chaloupková, E | 1 |
1 review available for hydrochlorothiazide and Gout
| Article | Year |
|---|---|
Uricosuric drugs: the once and future therapy for hyperuricemia?
Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Drug Dis | 2014 |
2 trials available for hydrochlorothiazide and Gout
| Article | Year |
|---|---|
Adverse treatment effects in the trial of the European Working Party on High Blood Pressure in the Elderly.
Topics: Aged; Depression; Double-Blind Method; Drug Therapy, Combination; Europe; Gout; Humans; Hydrochlorot | 1991 |
Antihypertensive effectiveness of very low doses of hydrochlorothiazide: results of the PHICOG Trial.
Topics: Adolescent; Adult; Age Factors; Aged; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Body Weigh | 1989 |
18 other studies available for hydrochlorothiazide and Gout
| Article | Year |
|---|---|
Comparison of new-onset gout in adults prescribed chlorthalidone vs. hydrochlorothiazide for hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Cohort Studies; Diuretics; Fem | 2014 |
Managing hypertensive patients with gout who take thiazide.
Topics: Adult; Aged; Diuretics; Female; Gout; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; | 2010 |
Gout.
Topics: Allopurinol; Antihypertensive Agents; Gout; Gout Suppressants; Humans; Hydrochlorothiazide; Hyperten | 2011 |
INFLAMMATORY POLYARTHRITIC DISEASE. IV. GOUT.
Topics: Arthritis; Aspirin; Chlorothiazide; Colchicine; Gout; Hydrochlorothiazide; Mecamylamine; Pempidine; | 1963 |
[URIC ACID METABOLISM AND SALIDIURETICS].
Topics: Aged; Chlorothiazide; Chlorthalidone; Diagnosis; Gout; Humans; Hydrochlorothiazide; Metabolism; Toxi | 1964 |
ACUTE ANURIA ASSOCIATED WITH CHLOROTHIAZIDE AND HYDROCHLOROTHIAZIDE THERAPY: RECOVERY.
Topics: Acute Kidney Injury; Anuria; Chlorothiazide; Diabetes Mellitus; Digoxin; Geriatrics; Gout; Hydrochlo | 1964 |
[SECONDARY ASPECIFIC EFFECTS OF BENZOTHIAZINIC DIURETICS].
Topics: Agranulocytosis; Amylases; Blood Glucose; Chlorothiazide; Diabetes Mellitus; Diuretics; Drug Eruptio | 1964 |
TREATMENT OF CONGESTIVE HEART FAILURE WITH TRIAMTERENE.
Topics: Blood; Diuresis; Diuretics; Drug Therapy; Gout; Heart Failure; Humans; Hydrochlorothiazide; Potassiu | 1965 |
[Influence of hydrochlorothiazide on the mechanism of excretion of uric acid. Clinico-experimental observations].
Topics: Biological Transport; Body Fluids; Chlorothiazide; Gout; Humans; Hydrochlorothiazide; Leadership; Ur | 1961 |
[The behavior of uricemia during treatment with spironolactone and with other diuretics].
Topics: Acetazolamide; Adolescent; Adult; Aged; Chlorthalidone; Clopamide; Diuretics; Ethacrynic Acid; Femal | 1967 |
Effects of diuretics on urate and calcium excretion.
Topics: Adult; Aged; Calcium; Chlorides; Furosemide; Glycolates; Gout; Humans; Hydrochlorothiazide; Middle A | 1981 |
[Gout tophi and Heberden nodules in hyperuricemia].
Topics: Aged; Aged, 80 and over; Arthritis, Gouty; Female; Fingers; Gout; Hand Deformities, Acquired; Humans | 1994 |
Pharmacokinetic and clinical studies of a new uricosuric agent - benzbromarone.
Topics: Adult; Aged; Arthritis; Benzbromarone; Benzofurans; Chemical Phenomena; Chemistry; Chronic Disease; | 1976 |
[Hyperuricemia due to diuretics].
Topics: Acetazolamide; Aged; Chlorothiazide; Chlorthalidone; Diuretics; Ethacrynic Acid; Furosemide; Gout; H | 1973 |
Drug-induced hyperuricemia prevented by probenecid.
Topics: Adult; Aged; Female; Gout; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Probenecid; | 1971 |
[Renal excretion of uric acid in various conditions inducing hyperuricemia].
Topics: Adolescent; Adult; Aged; Female; Gout; Humans; Hydrochlorothiazide; Hypertension, Renal; Kidney Fail | 1970 |
Diuretics. I--Benzothiadiazines and related drugs.
Topics: Benzothiadiazines; Calcium; Chlorothiazide; Diabetes Mellitus; Diuretics; Edema; Gout; Humans; Hydro | 1969 |
[Hyperuricemia in internal diseases].
Topics: Anemia; Cardiovascular Diseases; Gout; Hematologic Diseases; Humans; Hydrochlorothiazide; Kidney Dis | 1969 |