hydrochlorothiazide has been researched along with Experimental Mammary Neoplasms in 1 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In 2-year studies using dietary concentrations of 0, 250, 500 and 2000 ppm in rats and 0, 2500 and 5000 ppm in mice, survival of dosed and control groups of rats and mice was similar, as were body weights of mice." | 1.28 | Toxicology and carcinogenicity studies of diuretics in F344 rats and B6C3F1 mice. 1. Hydrochlorothiazide. ( Bucher, JR; Davis, WE; Elwell, MR; Eustis, SL; Haseman, JK; Huff, J; Meierhenry, EF, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bucher, JR | 1 |
| Huff, J | 1 |
| Haseman, JK | 1 |
| Eustis, SL | 1 |
| Elwell, MR | 1 |
| Davis, WE | 1 |
| Meierhenry, EF | 1 |
1 other study available for hydrochlorothiazide and Experimental Mammary Neoplasms
| Article | Year |
|---|---|
Toxicology and carcinogenicity studies of diuretics in F344 rats and B6C3F1 mice. 1. Hydrochlorothiazide.
Topics: Adenofibroma; Animals; Body Weight; Carcinogens; Chronic Kidney Disease-Mineral and Bone Disorder; D | 1990 |