Page last updated: 2024-10-28

hydrochlorothiazide and Diabetes Mellitus

hydrochlorothiazide has been researched along with Diabetes Mellitus in 79 studies

Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.

Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.

Research Excerpts

ExcerptRelevanceReference
"The impact of an ARB, with or without hydrochlorothiazide (HCTZ), on glycaemic factors and the risk for developing diabetes in hypertensive patients with the metabolic syndrome have not been fully assessed."9.14A 52-week prospective, cohort study of the effects of losartan with or without hydrochlorothiazide (HCTZ) in hypertensive patients with metabolic syndrome. ( Bastien, N; Hamet, P; Longo, N; Racine, N; Sampalis, JS, 2010)
"To investigate the impact of treatment on cardiovascular mortality and morbidity, we assessed outcomes in patients with hypertension and diabetes who received co-amilozide or nifedipine in the International Nifedipine GITS Study: Intervention as a Goal in Hypertension."9.10Outcomes with nifedipine GITS or Co-amilozide in hypertensive diabetics and nondiabetics in Intervention as a Goal in Hypertension (INSIGHT). ( Brown, M; Castaigne, A; de Leeuw, P; Mancia, G; Palmer, CR; Rosenthal, T; Ruilope, LM; Wagener, G, 2003)
"The combination of telmisartan/HCTZ is an effective and well-tolerated treatment option for patients with hypertension."8.86Telmisartan and hydrochlorothiazide combination therapy for the treatment of hypertension. ( Kjeldsen, SE; Mancia, G; Schmieder, RE; Unger, T, 2010)
"Simultaneous administration of indomethacin and Moduretic (Merck Sharp & Dohme, USA, 5 mg of amiloride HCl, 50 mg hydrochlorothiazide) to a 78-yr-old patient resulted in severe hyperkalemia twice."7.66Indomethacin- and Moduretic--induced hyperkalemia. ( Mor, R; Pitlik, S; Rosenfeld, JB, 1983)
"In previously monotherapy-treated, uncontrolled patients with hypertension, zofenopril 30-60 mg + HCTZ 12."5.19Zofenopril plus hydrochlorothiazide and irbesartan plus hydrochlorothiazide in previously treated and uncontrolled diabetic and non-diabetic essential hypertensive patients. ( Agabiti-Rosei, E; Manolis, A; Omboni, S; Zava, D, 2014)
"We assessed adverse metabolic effects of atenolol and hydrochlorothiazide among hypertensive patients with and without abdominal obesity using data from a randomized, open-label study of hypertensive patients without evidence of cardiovascular disease or diabetes mellitus."5.14Impact of abdominal obesity on incidence of adverse metabolic effects associated with antihypertensive medications. ( Beitelshees, AL; Boerwinkle, E; Chapman, AB; Cooper-DeHoff, RM; Gong, Y; Gums, JG; Hall, K; Johnson, JA; Parekh, V; Turner, ST; Wen, S; Zineh, I, 2010)
"The impact of an ARB, with or without hydrochlorothiazide (HCTZ), on glycaemic factors and the risk for developing diabetes in hypertensive patients with the metabolic syndrome have not been fully assessed."5.14A 52-week prospective, cohort study of the effects of losartan with or without hydrochlorothiazide (HCTZ) in hypertensive patients with metabolic syndrome. ( Bastien, N; Hamet, P; Longo, N; Racine, N; Sampalis, JS, 2010)
"The Avoiding Cardiovascular Events Through Combination Therapy in Patients Living With Systolic Hypertension (ACCOMPLISH) trial is the first cardiovascular outcome trial designed to compare initial use of 2 different fixed-dose antihypertensive regimens, benazepril plus hydrochlorothiazide vs benazepril plus amlodipine, on cardiovascular end points in hypertensive patients at high cardiovascular risk secondary to previous major events or presence of diabetes mellitus (DM)."5.13The diabetes subgroup baseline characteristics of the Avoiding Cardiovascular Events Through Combination Therapy in Patients Living With Systolic Hypertension (ACCOMPLISH) trial. ( Bakris, G; Dahlof, B; Hester, A; Jamerson, K; Pitt, B; Shi, V; Staikos-Byrne, L; Velasquez, E; Weber, M, 2008)
" STAR-LET was a 6-month extension of the Study of Trandolapril/Verapamil SR and Insulin Resistance (STAR), which assessed the effects of a fixed-dose renin-angiotensin system inhibitor (RASI)/hydrochlorothiazide (HCTZ) combination on changes in 2-hour oral glucose tolerance test (OGTT) results."5.13Reversal of diuretic-associated impaired glucose tolerance and new-onset diabetes: results of the STAR-LET study. ( Bacher, P; Bakris, G; Champion, A; Molitch, M; Sarafidis, P; Sowers, JR; Zhou, Q, 2008)
"To investigate the impact of treatment on cardiovascular mortality and morbidity, we assessed outcomes in patients with hypertension and diabetes who received co-amilozide or nifedipine in the International Nifedipine GITS Study: Intervention as a Goal in Hypertension."5.10Outcomes with nifedipine GITS or Co-amilozide in hypertensive diabetics and nondiabetics in Intervention as a Goal in Hypertension (INSIGHT). ( Brown, M; Castaigne, A; de Leeuw, P; Mancia, G; Palmer, CR; Rosenthal, T; Ruilope, LM; Wagener, G, 2003)
"The combination of telmisartan/HCTZ is an effective and well-tolerated treatment option for patients with hypertension."4.86Telmisartan and hydrochlorothiazide combination therapy for the treatment of hypertension. ( Kjeldsen, SE; Mancia, G; Schmieder, RE; Unger, T, 2010)
" We investigated the effect of switching from an angiotensin-converting enzyme inhibitor (ACEi) or angiotensin receptor blocker (ARB) to a combination of losartan and hydrochlorothiazide on left ventricular (LV) relaxation in patients with hypertension and diastolic dysfunction."3.78Adding thiazide to a rennin-angiotensin blocker regimen to improve left ventricular relaxation in diabetes and nondiabetes patients with hypertension. ( Fukuda, S; Ishii, K; Ito, H; Iwakura, K; Shimada, K; Takami, T; Watanabe, H; Yoshikawa, J, 2012)
"Simultaneous administration of indomethacin and Moduretic (Merck Sharp & Dohme, USA, 5 mg of amiloride HCl, 50 mg hydrochlorothiazide) to a 78-yr-old patient resulted in severe hyperkalemia twice."3.66Indomethacin- and Moduretic--induced hyperkalemia. ( Mor, R; Pitlik, S; Rosenfeld, JB, 1983)
"In patients with recurrent idiopathic nephrolithiasis we studied whether treatment with sodium cellulose phosphate leading to decreased intestinal calcium absorption could induce secondary hyperparathyroidism and whether thiazides which diminish calciuria would impair glucose tolerance."3.66[On the question of endocrine side effects in patients on medication for renal calcium stone disease (author's transl)]. ( Döring, B; Minne, H; Russmann, D; Uhl, K; Ziegler, R, 1980)
"The biguanides were a therapeutic enrichment particularly in the treatment of adipose elderly diabetics with obligatory diet."1.26[Indications and results of an additional differentiated pharmacotherapy of obesity]. ( Kucher, E, 1978)

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-199056 (70.89)18.7374
1990's2 (2.53)18.2507
2000's6 (7.59)29.6817
2010's15 (18.99)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Roshandel, G1
Khoshnia, M1
Poustchi, H1
Hemming, K1
Kamangar, F1
Gharavi, A1
Ostovaneh, MR1
Nateghi, A1
Majed, M1
Navabakhsh, B1
Merat, S1
Pourshams, A1
Nalini, M1
Malekzadeh, F1
Sadeghi, M1
Mohammadifard, N1
Sarrafzadegan, N1
Naemi-Tabiei, M1
Fazel, A1
Brennan, P1
Etemadi, A1
Boffetta, P1
Thomas, N1
Marshall, T1
Cheng, KK1
Malekzadeh, R1
Agabiti-Rosei, E2
Manolis, A2
Zava, D1
Omboni, S2
Karnes, JH2
Gong, Y3
Arwood, MJ1
Gums, JG3
Hall, KL1
Limacher, MC1
Johnson, JA3
Cooper-DeHoff, RM3
Chowdhury, EK1
Ademi, Z1
Moss, JR1
Wing, LMH1
Reid, CM1
Malacco, E2
Napoli, C1
Modesti, PA1
Parati, G1
Borghi, C1
Bakris, G2
Hester, A1
Weber, M1
Dahlof, B1
Pitt, B1
Velasquez, E1
Staikos-Byrne, L1
Shi, V1
Jamerson, K1
Manrique, C1
Johnson, M1
Sowers, JR2
Wen, S1
Beitelshees, AL2
Zineh, I1
Turner, ST2
Hall, K1
Parekh, V1
Chapman, AB2
Boerwinkle, E1
Kjeldsen, SE1
Schmieder, RE1
Unger, T1
Mancia, G2
Racine, N1
Hamet, P1
Sampalis, JS1
Longo, N1
Bastien, N1
Rosendorff, C1
McDonough, CW1
Vo, TT1
Langaee, TY1
Bailey, KR1
Del-Aguila, JL1
Boerwinkle, EA1
Pepine, CJ2
Takami, T1
Ito, H1
Ishii, K1
Shimada, K1
Iwakura, K1
Watanabe, H1
Fukuda, S1
Yoshikawa, J1
Suzuki, H1
Shimada, Y1
Fujiwara, K1
Al Balushi, KA1
Habib, JQ1
Al-Zakwani, I1
Brown, M1
Castaigne, A1
de Leeuw, P1
Palmer, CR1
Rosenthal, T1
Wagener, G1
Ruilope, LM1
KENNEDY, GC1
CRAWFORD, JD1
NICOLE, JC1
PULVER, W1
BOMPIANI, GD1
PANVINO, C1
SCHOTLAND, MG1
GRUMBACH, MM1
WEISSEL, W1
DOLLERY, CT3
PENTECOST, BL1
SAMAAN, NA1
MASSZI, F1
VARGA, P1
RICCI, PD1
LOMBARDI, M1
MASINI, G1
VALIENSI, M1
SAMAAN, N1
FRASER, R1
SCHWARTZ, W1
CALI, G1
PIETROPAOLO, C1
GELFAND, ML1
GARREN, MG1
ROWAN, RL1
VEHARANTA, T1
WOLFF, FW1
LANGDON, RG1
ANICHINI, M1
GARGANO, N1
BARTORELLI, C1
CHAZAN, JA1
BOSHELL, BR1
MAEKILAE, E1
VAAJA, U1
Ong, HT1
Staessen, JA1
Thijisq, L1
Fagard, R1
Celis, H1
Birkenhäger, WH1
Bulpitt, CJ1
de Leeuw, PW1
Fletcher, AE1
Forette, F1
Leonetti, G1
McCormack, P1
Nachev, C1
O'Brien, E1
Rodicio, JL1
Rosenfeld, J1
Sarti, C1
Tuomilehto, J1
Webster, J1
Yodfat, Y1
Zanchetti, A1
Cooper-Dehoff, R1
Cohen, JD1
Bakris, GL1
Messerli, FH1
Erdine, S1
Hewkin, AC1
Kupfer, S1
Molitch, M1
Zhou, Q1
Sarafidis, P1
Champion, A1
Bacher, P1
Jones, IG1
Pickens, PT1
Bloomgarden, ZT1
Ginsberg-Fellner, F1
Rayfield, EJ1
Bookman, J1
Brown, WV1
Mor, R1
Pitlik, S1
Rosenfeld, JB1
Rames, I1
Kristůfek, V1
Garrett, BN1
Raskin, P1
Kaplan, NM1
Marks, P1
Nimalasuriya, A1
Anderson, J1
Ziegler, R1
Uhl, K1
Minne, H1
Russmann, D1
Döring, B1
Himmel, W1
Lönker, B1
Kochen, MM1
Minker, E1
Koltai, M1
Blazsó, G1
McMahon, FG1
Ryan, JR1
Jain, AK1
Kucher, E1
Pakrashi, A1
Mukherjee, SK1
Káldor, A1
Gachályi, B1
Sebestyén, K1
Kmoch, J2
Svoboda, Z2
Lundgren, H1
Bengtsson, C1
Lapidus, L1
Bengtsson, L1
Ferguson, RP1
Kohner, EM1
Lowy, C1
Schumer, B1
Ravina, A1
Kain, T1
Hicks, BH1
Ward, JD1
Jarrett, RJ1
Keen, H1
Wise, P1
Nath, K2
Sikka, KK2
Saxena, S1
Tandon, AP2
Kusus, T1
Lydtin, H1
Zöllner, N1
Ikeda, T1
Agarwal, SN1
Guidoux, R1
Heimsoth, V1
Drásilová, L2
Kocí, V2
Senft, G2
Schwarzbach, W1
Bossini, A1
Bologna, E1
Standl, E2
Haslbeck, H1
Geser, CA2
Mehnert, H2
Haslbeck, M1
Förster, H1
Gross, W1
Spech, HJ1
Wiecko, W1
el-Ebrashy, N1
el-Danasoury, M1
Higazi, AM1
Pistolese, M1
Rosica, V1
Gallo Curcio, C1
Fabian, D1
Scotti, G1
Gatti, A1
Shul'tsev, GP1

Clinical Trials (9)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Polypill Strategy for Evidence-Based Management of Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention in an Underserved Patient Population[NCT05514938]Phase 260 participants (Anticipated)Interventional2022-11-30Recruiting
Effectiveness of Polypill for Primary Prevention of Cardiovascular Disease (PolyPars): Study Design and Rationale for a Pragmatic Cluster Randomized Controlled Trial[NCT03459560]Phase 34,415 participants (Actual)Interventional2015-12-20Active, not recruiting
Fixed-dose Combination Therapy (PolyPill) in Primary and Secondary Prevention of Cardiovascular Disease in Middle-aged and Elderly Iranians[NCT01271985]Phase 38,410 participants (Actual)Interventional2011-02-28Completed
Polipill and RiscOMeter to Prevent StrOke and CogniTive ImpairmEnt in Primary Health Care[NCT05155137]Phase 312,268 participants (Anticipated)Interventional2021-12-20Recruiting
Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR)[NCT00246519]Phase 41,701 participants (Actual)Interventional2005-10-31Completed
52 Week Study to Evaluate the Effects of LOSARTAN 50 mg, 100 mg, 100/12.5 mg HCTZ, 100/25 mg HCTZ on Metabolic Parameters, Blood Pressure and Safety in Hypertensive Patients With Metabolic Syndrome[NCT00546052]Phase 31,738 participants (Actual)Interventional2005-09-01Completed
Stroke Prediction Study Using a Model Based on Internet Search Queries[NCT04755959]450 participants (Anticipated)Observational2021-02-28Not yet recruiting
INternational VErapamil SR Trandolapril STudy[NCT00133692]Phase 422,000 participants Interventional1997-09-30Completed
A Randomised, Double-blind, Placebo Controlled, Parallel Group, Multi-centre Trial in Adult Subjects With Newly Diagnosed Type 1 Diabetes Mellitus Investigating the Effect of Verapamil SR on Preservation of Beta-cell Function (Ver-A-T1D)[NCT04545151]Phase 2138 participants (Anticipated)Interventional2021-02-08Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Blood Pressure Response (Delta BP (After 18 Weeks of Medication - Baseline)).

(NCT00246519)
Timeframe: baseline to 18 weeks of treatment

InterventionmmHg (Mean)
Atenolol +HCTZ Arm-12.06
HCTZ + Atenolol-13.33

Absolute Change in C Reactive Protein Between Baseline and 52 Week Assessments

Absolute Change in C Reactive Protein Between Baseline and 52 week assessments: C Reactive Protein 52 weeks - C Reactive Protein Baseline. (NCT00546052)
Timeframe: 52 Weeks - Baseline

Interventionmg/L (Mean)
Losartan +/- Hydrochlorothiazide-0.36

Absolute Change in Uric Acid Between Baseline and 52 Week Assessments

Absolute Change in Uric Acid Between Baseline and 52 week assessments: Uric Acid 52 weeks - Uric Acid Baseline. (NCT00546052)
Timeframe: 52 Weeks - Baseline

Interventionmmol/L (Mean)
Losartan +/- Hydrochlorothiazide-19.17

Change in Body Mass Index Between Baseline and 52 Week Assessments

Absolute change in Body Mass Index Baseline and 52 week assessments (NCT00546052)
Timeframe: 52 Weeks - Baseline

InterventionKg/m2 (Mean)
Losartan +/- Hydrochlorothiazide-7.3

Change in Diastolic Blood Pressure Between Baseline and 52 Week Assessments

Absolute change in Diastolic Blood Pressure between baseline and 52 week assessments. (NCT00546052)
Timeframe: 52 Weeks - Baseline

Interventionmm Hg (Mean)
Losartan +/- Hydrochlorothiazide-9.84

Change in Fasting Blood Glucose Between Baseline and 52 Weeks Assessments

Absolute Change in Fasting Blood Glucose Measurements between Baseline and 52 week assessments. (NCT00546052)
Timeframe: 52 Weeks - Baseline

Interventionmmol/L (Mean)
Losartan +/- Hydrochlorothiazide0.02

Change in Hemoglobin A1c Between 52 Weeks and Baseline

Absolute Change in Hemoglobin A1c between 52 week measurement and baseline value. (NCT00546052)
Timeframe: 52 Weeks - Baseline

InterventionPercent (Median)
Losartan +/- Hydrochlorothiazide0.04

Change in Systolic Blood Pressure Between Baseline and 52 Week Assessments

Absolute change in Systolic Blood Pressure between baseline and 52 week assessments. (NCT00546052)
Timeframe: 52 Weeks - Baseline

Interventionmm Hg (Mean)
Losartan +/- Hydrochlorothiazide-16.95

Change in Waist Circumference Between Baseline and 52 Week Assessments

Absolute change in Waist Circumference between baseline and 52 week assessments (NCT00546052)
Timeframe: 52 Weeks - Baseline

Interventioncm (Mean)
Losartan +/- Hydrochlorothiazide-1.28

Percent Change in High Density Lipoprotein-C Between Baseline and 52 Week Assessments

Percent Change in HDL-C Between Baseline and 52 week assessments: 100% x [(HDL-C 52 Weeks - HDL-C 52 Baseline) / (HDL-C Baseline)]. (NCT00546052)
Timeframe: 52 Weeks - Baseline

InterventionPercent Change (Mean)
Losartan +/- Hydrochlorothiazide0.21

Percent Change in Low Density Lipoprotein-C Between Baseline and 52 Week Assessments

Percent Change in LDL-C Between Baseline and 52 week assessments: 100% x [(LDL-C 52 Weeks - LDL-C Baseline) / (LDL-C Baseline)]. (NCT00546052)
Timeframe: 52 Weeks - Baseline

InterventionPercent Change (Mean)
Losartan +/- Hydrochlorothiazide-1.49

Percent Change in Total Cholesterol Between Baseline and 52 Week Assessments

Percent Change in Total Cholesterol Between Baseline and 52 week assessments: 100% x [(Total Cholesterol 52 weeks - Total Cholesterol Baseline) / (Total Cholesterol Baseline)]. (NCT00546052)
Timeframe: 52 Weeks - Baseline

InterventionPercent Change (Mean)
Losartan +/- Hydrochlorothiazide-2.98

Percent Change in Triglycerides Between Baseline and 52 Week Assessments

Percent Change in Triglycerides Between Baseline and 52 week assessments: 100% x [(Triglycerides 52 Weeks - Triglycerides Baseline) / (Triglycerides Baseline)]. (NCT00546052)
Timeframe: 52 Weeks - Baseline

InterventionPercent Change (Median)
Losartan +/- Hydrochlorothiazide1.09

Target Blood Pressure

Target Blood Pressure defined as Systolic Blood Pressure/Diastolic Blood Pressure ≤ 140/90 mm Hg at 52 weeks (NCT00546052)
Timeframe: 52 Weeks

,,
InterventionParticipants (Number)
Achieved Target Blood PressureDid NOT achieve target Blood Pressure
Overall Intend to Treat1200514
Overall Per Protocol1200311
Overall Total1200538

Reviews

3 reviews available for hydrochlorothiazide and Diabetes Mellitus

ArticleYear
Efficacy of Zofenopril vs. Irbesartan in Combination with a Thiazide Diuretic in Hypertensive Patients with Multiple Risk Factors not Controlled by a Previous Monotherapy: A Review of the Double-Blind, Randomized "Z" Studies.
    Advances in therapy, 2017, Volume: 34, Issue:4

    Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive A

2017
Telmisartan and hydrochlorothiazide combination therapy for the treatment of hypertension.
    Current medical research and opinion, 2010, Volume: 26, Issue:4

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; B

2010
[Hypertension--diuretics as antihypertensive agents].
    Nihon rinsho. Japanese journal of clinical medicine, 1970, Volume: 28, Issue:4

    Topics: Aged; Antihypertensive Agents; Arthritis; Benzothiadiazines; Blood Pressure; Chlorothiazide; Chlorth

1970

Trials

16 trials available for hydrochlorothiazide and Diabetes Mellitus

ArticleYear
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
    Lancet (London, England), 2019, 08-24, Volume: 394, Issue:10199

    Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur

2019
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
    Lancet (London, England), 2019, 08-24, Volume: 394, Issue:10199

    Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur

2019
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
    Lancet (London, England), 2019, 08-24, Volume: 394, Issue:10199

    Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur

2019
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
    Lancet (London, England), 2019, 08-24, Volume: 394, Issue:10199

    Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur

2019
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
    Lancet (London, England), 2019, 08-24, Volume: 394, Issue:10199

    Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur

2019
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
    Lancet (London, England), 2019, 08-24, Volume: 394, Issue:10199

    Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur

2019
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
    Lancet (London, England), 2019, 08-24, Volume: 394, Issue:10199

    Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur

2019
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
    Lancet (London, England), 2019, 08-24, Volume: 394, Issue:10199

    Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur

2019
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
    Lancet (London, England), 2019, 08-24, Volume: 394, Issue:10199

    Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur

2019
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
    Lancet (London, England), 2019, 08-24, Volume: 394, Issue:10199

    Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur

2019
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
    Lancet (London, England), 2019, 08-24, Volume: 394, Issue:10199

    Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur

2019
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
    Lancet (London, England), 2019, 08-24, Volume: 394, Issue:10199

    Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur

2019
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
    Lancet (London, England), 2019, 08-24, Volume: 394, Issue:10199

    Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur

2019
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
    Lancet (London, England), 2019, 08-24, Volume: 394, Issue:10199

    Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur

2019
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
    Lancet (London, England), 2019, 08-24, Volume: 394, Issue:10199

    Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur

2019
Effectiveness of polypill for primary and secondary prevention of cardiovascular diseases (PolyIran): a pragmatic, cluster-randomised trial.
    Lancet (London, England), 2019, 08-24, Volume: 394, Issue:10199

    Topics: Adult; Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressur

2019
Zofenopril plus hydrochlorothiazide and irbesartan plus hydrochlorothiazide in previously treated and uncontrolled diabetic and non-diabetic essential hypertensive patients.
    Advances in therapy, 2014, Volume: 31, Issue:2

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Biphenyl Compounds; Captopril; Case-Control Studie

2014
Cost-utility of angiotensin-converting enzyme inhibitor-based treatment compared with thiazide diuretic-based treatment for hypertension in elderly Australians considering diabetes as comorbidity.
    Medicine, 2015, Volume: 94, Issue:9

    Topics: Age Factors; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Australia; Cardiovas

2015
The diabetes subgroup baseline characteristics of the Avoiding Cardiovascular Events Through Combination Therapy in Patients Living With Systolic Hypertension (ACCOMPLISH) trial.
    Journal of the cardiometabolic syndrome, 2008,Fall, Volume: 3, Issue:4

    Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Benzazepines; Blood Glucose; Blood Press

2008
Impact of abdominal obesity on incidence of adverse metabolic effects associated with antihypertensive medications.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:1

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Atenolol; Diabetes Mellitus; Drug Therapy, Combina

2010
A 52-week prospective, cohort study of the effects of losartan with or without hydrochlorothiazide (HCTZ) in hypertensive patients with metabolic syndrome.
    Journal of human hypertension, 2010, Volume: 24, Issue:11

    Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Glu

2010
Association of KCNJ1 variation with change in fasting glucose and new onset diabetes during HCTZ treatment.
    The pharmacogenomics journal, 2013, Volume: 13, Issue:5

    Topics: Aged; Antihypertensive Agents; Atenolol; Diabetes Mellitus; Fasting; Female; Glucose; Haplotypes; Hu

2013
Outcomes with nifedipine GITS or Co-amilozide in hypertensive diabetics and nondiabetics in Intervention as a Goal in Hypertension (INSIGHT).
    Hypertension (Dallas, Tex. : 1979), 2003, Volume: 41, Issue:3

    Topics: Aged; Amiloride; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular D

2003
Effects of immediate versus delayed antihypertensive therapy on outcome in the Systolic Hypertension in Europe Trial.
    Journal of hypertension, 2004, Volume: 22, Issue:4

    Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus; Dihydrop

2004
Predictors of development of diabetes mellitus in patients with coronary artery disease taking antihypertensive medications (findings from the INternational VErapamil SR-Trandolapril STudy [INVEST]).
    The American journal of cardiology, 2006, Oct-01, Volume: 98, Issue:7

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Body Mass Index; Calcium Chann

2006
Predictors of development of diabetes mellitus in patients with coronary artery disease taking antihypertensive medications (findings from the INternational VErapamil SR-Trandolapril STudy [INVEST]).
    The American journal of cardiology, 2006, Oct-01, Volume: 98, Issue:7

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Body Mass Index; Calcium Chann

2006
Predictors of development of diabetes mellitus in patients with coronary artery disease taking antihypertensive medications (findings from the INternational VErapamil SR-Trandolapril STudy [INVEST]).
    The American journal of cardiology, 2006, Oct-01, Volume: 98, Issue:7

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Body Mass Index; Calcium Chann

2006
Predictors of development of diabetes mellitus in patients with coronary artery disease taking antihypertensive medications (findings from the INternational VErapamil SR-Trandolapril STudy [INVEST]).
    The American journal of cardiology, 2006, Oct-01, Volume: 98, Issue:7

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Body Mass Index; Calcium Chann

2006
Reversal of diuretic-associated impaired glucose tolerance and new-onset diabetes: results of the STAR-LET study.
    Journal of the cardiometabolic syndrome, 2008,Winter, Volume: 3, Issue:1

    Topics: Analysis of Variance; Chi-Square Distribution; Diabetes Mellitus; Diuretics; Female; Glucose Toleran

2008
The hypouricaemic effect of tienilic acid: experience in patients with hyperuricaemia.
    Postgraduate medical journal, 1979, Volume: 55 Suppl 3

    Topics: Adult; Aged; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Double-Blind Method; Drug A

1979
Antihypertensive drugs and glucose metabolism: comparison between a diuretic, a beta-blocker and felodipine, a new calcium antagonist in subjects with arterial hypertension and diabetes.
    Journal of internal medicine, 1990, Volume: 228, Issue:6

    Topics: Aged; Blood Glucose; Diabetes Mellitus; Double-Blind Method; Felodipine; Female; Glucose Tolerance T

1990
Effect of diuretic therapy on glucose tolerance in hypertensive patients.
    Lancet (London, England), 1971, May-15, Volume: 1, Issue:7707

    Topics: Age Factors; Blood Glucose; Body Weight; Diabetes Mellitus; Diuretics; Ethacrynic Acid; Fasting; Fat

1971
A controlled study of clopamide, clorexolone, and hydrochlorothiazide in diabetics.
    Metabolism: clinical and experimental, 1973, Volume: 22, Issue:2

    Topics: Adult; Aged; Amides; Blood Glucose; Blood Pressure; Body Weight; Clinical Trials as Topic; Clopamide

1973
[Saluretic treatment of hypertension and uric acid level in serum. Clinical test of a combination of hydrochlorothiazide and probenecid].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:11

    Topics: Adult; Aged; Alanine Transaminase; Blood Glucose; Blood Pressure; Blood Protein Electrophoresis; Bod

1969

Other Studies

60 other studies available for hydrochlorothiazide and Diabetes Mellitus

ArticleYear
Alteration in fasting glucose after prolonged treatment with a thiazide diuretic.
    Diabetes research and clinical practice, 2014, Volume: 104, Issue:3

    Topics: Adolescent; Adult; Aged; Blood Glucose; Diabetes Mellitus; Diuretics; Fasting; Female; Follow-Up Stu

2014
Thiazide diuretics alone or with beta-blockers impair glucose metabolism in hypertensive patients with abdominal obesity.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:1

    Topics: Adrenergic beta-Antagonists; Atenolol; Diabetes Mellitus; Diuretics; Drug Therapy, Combination; Fast

2010
Nebivolol/hydrochlorothiazide (HCTZ) combination in patients with essential hypertension: a pooled analysis from five non-interventional studies with a focus on diabetic and elderly patients.
    European review for medical and pharmacological sciences, 2010, Volume: 14, Issue:5

    Topics: Age Factors; Aged; Aged, 80 and over; Antihypertensive Agents; Benzopyrans; Blood Pressure; Diabetes

2010
Why are we still using hydrochlorothiazide?
    Journal of clinical hypertension (Greenwich, Conn.), 2011, Volume: 13, Issue:12

    Topics: Antihypertensive Agents; Diabetes Mellitus; Diuretics; Humans; Hydrochlorothiazide; Hypertension; Hy

2011
Adding thiazide to a rennin-angiotensin blocker regimen to improve left ventricular relaxation in diabetes and nondiabetes patients with hypertension.
    Drug design, development and therapy, 2012, Volume: 6

    Topics: Adult; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; C-Reactive

2012
Combination therapy with losartan/hydrochlorothiazide for blood pressure reduction and goal attainment in a real-world clinical setting in Japan.
    Therapeutic advances in cardiovascular disease, 2012, Volume: 6, Issue:6

    Topics: Age Factors; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure;

2012
Comparative efficacy of irbesartan/ hydrochlorothiazide and valsartan/hydrochlorothiazide combination in lowering blood pressure: a retrospective observational study in Oman.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2013, Volume: 22, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Diabete

2013
Treatment of diabetes insipidus with hydrochlorothiazide.
    Lancet (London, England), 1959, Apr-25, Volume: 1, Issue:7078

    Topics: Acetazolamide; Diabetes Insipidus; Diabetes Mellitus; Diabetes Mellitus, Experimental; Hydrochloroth

1959
[Hyperglycemic effect by means of salidiuretics in diabetes mellitus].
    Helvetica medica acta, 1962, Volume: 29

    Topics: Chlorthalidone; Diabetes Mellitus; Humans; Hydrochlorothiazide; Hyperglycemia

1962
[The influence of sulfonamide diuretics on blood sugar regulation].
    La Clinica terapeutica, 1962, Dec-31, Volume: 23

    Topics: Blood Glucose; Chlorothiazide; Chlorthalidone; Diabetes Mellitus; Diuretics; Hydrochlorothiazide; Su

1962
Neutropenia in an infant secondary to hydrochlorothiazide therapy: with a review of hematologic reactions to "thiazide" drugs.
    Pediatrics, 1963, Volume: 31

    Topics: Agranulocytosis; Diabetes Mellitus; Drug Hypersensitivity; Humans; Hydrochlorothiazide; Neutropenia;

1963
[Clinical contribution to the diabetogenic effect of saluretics].
    Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1962, Volume: 43

    Topics: Chlorothiazide; Chlorthalidone; Diabetes Mellitus; Diuretics; Humans; Hydrochlorothiazide

1962
Drug-induced diabetes.
    Lancet (London, England), 1962, Oct-13, Volume: 2, Issue:7259

    Topics: Benzothiadiazines; Diabetes Mellitus; Humans; Hydrochlorothiazide; Hypertension

1962
[ON THIAZIDE DERIVATIVES AND CARBOHYDRATE METABOLISM].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1963, Jul-01, Volume: 18

    Topics: Antihypertensive Agents; Carbohydrate Metabolism; Chlorothiazide; Diabetes Mellitus; Glucose Toleran

1963
[MODERN DIURETICS AND DIABETES MELLITUS].
    La Clinica terapeutica, 1963, Jul-31, Volume: 26

    Topics: Diabetes Mellitus; Diuresis; Diuretics; Glucose Tolerance Test; Glycosuria; Humans; Hydrochlorothiaz

1963
DIABETOGENIC ACTION OF BENZOTHIADIAZINES: SERUM-INSULIN-LIKE ACTIVITY IN DIABETES WORSENED OR PRECIPITATED BY THIAZIDE DIURETICS.
    Lancet (London, England), 1963, Dec-14, Volume: 2, Issue:7320

    Topics: Benzothiadiazines; Blood Chemical Analysis; Chlorothiazide; Diabetes Mellitus; Glucose Tolerance Tes

1963
MEBUTAMATE AND HYDROCHLOROTHIAZIDE IN HYPERTENSION.
    Journal of the American Geriatrics Society, 1964, Volume: 12

    Topics: Antihypertensive Agents; Arthritis; Arthritis, Rheumatoid; Blood Pressure Determination; Carbamates;

1964
[GRAVE DISORDER OF CARBOHYDRATE METABOLISM IN A PATIENT WITH HEPATIC CIRRHOSIS FOLLOWING TREATMENT WITH HYDROCHLOROTHIAZIDE].
    Il Progresso medico, 1963, Jul-31, Volume: 19

    Topics: Acidosis; Blood Chemical Analysis; Carbohydrate Metabolism; Diabetes Mellitus; Hydrochlorothiazide;

1963
ACUTE ANURIA ASSOCIATED WITH CHLOROTHIAZIDE AND HYDROCHLOROTHIAZIDE THERAPY: RECOVERY.
    New York state journal of medicine, 1964, Jul-15, Volume: 64

    Topics: Acute Kidney Injury; Anuria; Chlorothiazide; Diabetes Mellitus; Digoxin; Geriatrics; Gout; Hydrochlo

1964
[THIAZIDE DIURETICS AS DIABETOGENIC AGENTS].
    Suomen laakarilehti. Finlands lakartidning, 1964, Jul-20, Volume: 19

    Topics: Chlorothiazide; Diabetes Mellitus; Diuretics; Hydrochlorothiazide; Pharmacology; Sodium Chloride Sym

1964
CONJOINT CLINIC ON DRUGS AND DIABETES.
    Journal of chronic diseases, 1964, Volume: 17

    Topics: Adrenalectomy; Antihypertensive Agents; Benzothiadiazines; Biomedical Research; Blood; Blood Glucose

1964
[SECONDARY ASPECIFIC EFFECTS OF BENZOTHIAZINIC DIURETICS].
    Minerva medica, 1964, Sep-08, Volume: 55

    Topics: Agranulocytosis; Amylases; Blood Glucose; Chlorothiazide; Diabetes Mellitus; Diuretics; Drug Eruptio

1964
ETIOLOGICAL FACTORS IN THIAZIDE-INDUCED OR AGGRAVATED DIABETES MELLITUS.
    Diabetes, 1965, Volume: 14

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Amylases; Blood Chemical Analysis; Blood Urea Nitrogen;

1965
HYDROCHLOROTHIAZIDE AND SALIVA. AN EXPERIMENTAL INVESTIGATION OF THE EFFECT OF HYDROCHLOROTHIAZIDE ON THE SALIVARY SECRETION IN MAN.
    Arzneimittel-Forschung, 1964, Volume: 14

    Topics: Diabetes Mellitus; Humans; Hydrochlorothiazide; Male; Saliva

1964
LIFE: losartan versus atenolol.
    Lancet (London, England), 2003, Oct-25, Volume: 362, Issue:9393

    Topics: Antihypertensive Agents; Atenolol; Comorbidity; Death, Sudden, Cardiac; Diabetes Mellitus; Drug Ther

2003
Diabetes mellitus following oral diuretics.
    The Practitioner, 1967, Volume: 199, Issue:190

    Topics: Diabetes Mellitus; Female; Furosemide; Humans; Hydrochlorothiazide; Middle Aged

1967
Elevated hemoglobin A1c and low-density lipoprotein cholesterol levels in thiazide-treated diabetic patients.
    The American journal of medicine, 1984, Volume: 77, Issue:5

    Topics: Cholesterol; Diabetes Mellitus; Female; Furosemide; Hemoglobin A; Humans; Hydrochlorothiazide; Lipop

1984
Indomethacin- and Moduretic--induced hyperkalemia.
    Israel journal of medical sciences, 1983, Volume: 19, Issue:6

    Topics: Aged; Amiloride; Diabetes Complications; Diabetes Mellitus; Drug Combinations; Drug Interactions; Fe

1983
[Comparison of the effects of 2 different diuretics in the treatment of hypertension in diabetics].
    Vnitrni lekarstvi, 1983, Volume: 29, Issue:5

    Topics: Acetazolamide; Aged; Blood Glucose; Blood Pressure; Diabetes Complications; Diabetes Mellitus; Femal

1983
Metoprolol in diabetes mellitus: effect on glucose homeostasis.
    Clinical science (London, England : 1979), 1980, Volume: 59 Suppl 6

    Topics: Aged; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Female; Glucagon; Homeostasis; Human

1980
The glucose tolerance test in hypertensive patients treated long term with thiazide diuretics.
    The Practitioner, 1981, Volume: 225, Issue:1353

    Topics: Diabetes Mellitus; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hypertension; Risk

1981
[On the question of endocrine side effects in patients on medication for renal calcium stone disease (author's transl)].
    Der Urologe. Ausg. A, 1980, Volume: 19, Issue:4

    Topics: Calcium; Cellulose; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Hydrochlorothiazide;

1980
[Relevance of general practitioner's prescriptions for hospital pharmacotherapy. A survey of hospital physicians].
    Deutsche medizinische Wochenschrift (1946), 1996, Nov-22, Volume: 121, Issue:47

    Topics: Aged; Attitude of Health Personnel; Captopril; Data Interpretation, Statistical; Diabetes Mellitus;

1996
Diabetes-induced alterations of autonomic nerve function in the cat.
    Acta physiologica Academiae Scientiarum Hungaricae, 1978, Volume: 51, Issue:4

    Topics: Animals; Cat Diseases; Cats; Cholinesterases; Cortisone; Diabetes Mellitus; Diabetes Mellitus, Exper

1978
[Indications and results of an additional differentiated pharmacotherapy of obesity].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1978, Oct-15, Volume: 33, Issue:20

    Topics: Adolescent; Adult; Aged; Biguanides; Diabetes Mellitus; Diet, Reducing; Female; Furosemide; Humans;

1978
A new method for the production of experimental diabetes in rabbits.
    The Journal of endocrinology, 1975, Volume: 66, Issue:2

    Topics: Administration, Oral; Animals; Chlorpropamide; Diabetes Mellitus; Disease Models, Animal; Drug Syner

1975
[The connection between Moduretic and diabetes mellitus. A case report].
    Lakartidningen, 1975, Jun-18, Volume: 72, Issue:25

    Topics: Aged; Amiloride; Diabetes Mellitus; Female; Humans; Hydrochlorothiazide; Pyrazines

1975
Diabetogenic effect of oral diuretics in asymptomatic diabetes.
    International journal of clinical pharmacology and biopharmacy, 1975, Volume: 11, Issue:3

    Topics: Adult; Aged; Diabetes Mellitus; Diuretics; Ethacrynic Acid; Furosemide; Glucose Tolerance Test; Huma

1975
[Effect of long-term administration of hydrochlorothiazide on glycide tolerance in diabetic patients].
    Vnitrni lekarstvi, 1975, Volume: 21, Issue:10

    Topics: Aged; Carbohydrate Metabolism; Diabetes Mellitus; Energy Metabolism; Female; Humans; Hydrochlorothia

1975
A comparison of steroid and thiazide diabetes.
    Connecticut medicine, 1986, Volume: 50, Issue:8

    Topics: Aged; Diabetes Mellitus; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Prednisone

1986
[Chlorpropamide, thiazides and congestive heart failure].
    Harefuah, 1974, Feb-15, Volume: 86, Issue:4

    Topics: Aged; Chlorpropamide; Diabetes Mellitus; Diuresis; Diuretics; Glyburide; Heart Failure; Humans; Hydr

1974
Effect of thiazides on blood sugar level in oedematous and non oedematous states.
    The Journal of the Association of Physicians of India, 1972, Volume: 20, Issue:6

    Topics: Adult; Bendroflumethiazide; Benzothiadiazines; Blood Glucose; Diabetes Mellitus; Diuretics; Edema; F

1972
Effect of hydrochlorothiazides on blood sugar level in diabetics and nondiabetics.
    The Journal of the Association of Physicians of India, 1969, Volume: 17, Issue:1

    Topics: Diabetes Mellitus; Humans; Hydrochlorothiazide; Hyperglycemia

1969
[Diabetogenic effects of thiazide diuretics and the solvent N-monomethyl-acetamide in rats].
    Diabetologia, 1969, Volume: 5, Issue:1

    Topics: Acetates; Amides; Animals; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Experimental; Glucos

1969
[Impairment of carbohydrate tolerance by saluretics in diabetics treated with insulin].
    Klinische Wochenschrift, 1969, Sep-01, Volume: 47, Issue:17

    Topics: Blood Glucose; Diabetes Mellitus; Female; Humans; Hydrochlorothiazide; Insulin; Male; Middle Aged

1969
[Experience with the administration of hydrochlorothiazide in diabetics].
    Vnitrni lekarstvi, 1970, Volume: 16, Issue:11

    Topics: Aged; Diabetes Mellitus; Diet Therapy; Female; Humans; Hydrochlorothiazide; Male; Middle Aged

1970
[Disorders of carbohydrate metabolism following diuretically effective agents].
    Therapeutische Umschau. Revue therapeutique, 1967, Volume: 24, Issue:8

    Topics: Arteriosclerosis; Carbohydrate Metabolism; Chlorothiazide; Diabetes Mellitus; Diazoxide; Furosemide;

1967
["Therapy with saluretics and insulin resistance in diabetes mellitus"].
    Medizinische Klinik, 1967, Oct-27, Volume: 62, Issue:43

    Topics: Diabetes Mellitus; Diabetic Coma; Diuretics; Humans; Hydrochlorothiazide; Insulin; Insulin Resistanc

1967
[Research on hyperglycemia caused by saluretics].
    Il Policlinico. Sezione medica, 1967, Volume: 74, Issue:2

    Topics: Diabetes Mellitus; Diuresis; Diuretics; Electrolytes; Female; Furosemide; Heart Diseases; Humans; Hy

1967
[Studies on the question of an interrelationship between saluretic acting thiazide derivatives and thiamine in diabetes].
    Klinische Wochenschrift, 1968, Nov-01, Volume: 46, Issue:21

    Topics: Blood Glucose; Diabetes Mellitus; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Natriuresis;

1968
[Studies on the influrence of saluretic thiazide derivatives and thiamine on carbohydrate metabolism].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1968, Volume: 74

    Topics: Carbohydrate Metabolism; Diabetes Mellitus; Diuretics; Furosemide; Glucose Tolerance Test; Humans; H

1968
[Carbohydrate metabolism disorders due to saluretic drugs. A contribution to the genesis of so-called "thiazide diabetes"].
    Der Landarzt, 1968, Jan-31, Volume: 44, Issue:3

    Topics: Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus; Diuretics; Erythrocytes; Ethacrynic Acid;

1968
[Diabetic acidosis during hydrochlorothiazide treatment].
    Maroc medical, 1968, Volume: 48, Issue:510

    Topics: Acidosis; Aged; Diabetes Mellitus; Female; Humans; Hydrochlorothiazide

1968
[Contribution to the problem of the diabetogenic effect of thiazide diuretics].
    Vnitrni lekarstvi, 1969, Volume: 15, Issue:3

    Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus; Female; Humans; Hydrochlorothiazide; Middle Aged; Obe

1969
Diuretics. I--Benzothiadiazines and related drugs.
    British medical journal, 1969, Jul-19, Volume: 3, Issue:5663

    Topics: Benzothiadiazines; Calcium; Chlorothiazide; Diabetes Mellitus; Diuretics; Edema; Gout; Humans; Hydro

1969
Hyperuricaemic and hyperglycaemic effects of thiazides in non-prediabetics.
    The Journal of the Egyptian Medical Association, 1965, Volume: 48, Issue:7

    Topics: Blood; Diabetes Mellitus; Heart Failure; Humans; Hydrochlorothiazide; Polythiazide; Prediabetic Stat

1965
[Thiazide diuretics and changes in carbohydrate metabolism. Clinical study of 30 cases].
    Minerva medica, 1966, Sep-29, Volume: 57, Issue:78

    Topics: Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus; Glucose Tolerance Test; Humans; Hydrochlo

1966
[Contribution to the effect of thiazide compounds on the development of diabetes mellitus].
    Vnitrni lekarstvi, 1966, Volume: 12, Issue:9

    Topics: Adult; Aged; Chlorothiazide; Czechoslovakia; Diabetes Mellitus; Female; Health Surveys; Humans; Hydr

1966
[Effects of triamterene and the association of triamterene and hydrochlorothiazide on carbohydrate metabolism in senile subjects].
    La Clinica terapeutica, 1966, Aug-31, Volume: 38, Issue:4

    Topics: Aged; Carbohydrate Metabolism; Diabetes Mellitus; Humans; Hydrochlorothiazide; Triamterene

1966
[On the diabetogenic action of hypothiazide].
    Klinicheskaia meditsina, 1966, Volume: 44, Issue:8

    Topics: Adult; Diabetes Mellitus; Female; Humans; Hydrochlorothiazide

1966