hydrochlorothiazide has been researched along with Death, Sudden in 5 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
Death, Sudden: The abrupt cessation of all vital bodily functions, manifested by the permanent loss of total cerebral, respiratory, and cardiovascular functions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a randomized primary prevention trial including 3,234 men with mild to moderate uncomplicated hypertension, the effect of the beta-blocker metoprolol or a thiazide diuretic as an initial antihypertensive therapy was compared regarding the risk of sudden cardiovascular death during a follow-up ranging from 2." | 5.07 | Primary prevention of sudden cardiovascular death in hypertensive patients. Mortality results from the MAPHY Study. ( Barber, H; Berglund, G; Eliasson, K; Elmfeldt, D; Jastrup, B; Karatzas, N; Leer, J; Olsson, G; Tuomilehto, J; Warnold, I, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mullick, FG | 1 |
| McAllister, HA | 1 |
| Olsson, G | 1 |
| Tuomilehto, J | 1 |
| Berglund, G | 1 |
| Elmfeldt, D | 1 |
| Warnold, I | 1 |
| Barber, H | 1 |
| Eliasson, K | 1 |
| Jastrup, B | 1 |
| Karatzas, N | 1 |
| Leer, J | 1 |
| Kuller, LH | 1 |
| Hulley, SB | 1 |
| Cohen, JD | 1 |
| Neaton, J | 1 |
| Messerli, FH | 1 |
| Nunez, BD | 1 |
| Nunez, MM | 1 |
| Garavaglia, GE | 1 |
| Schmieder, RE | 1 |
| Ventura, HO | 1 |
| Holland, OB | 1 |
| Kuhnert, L | 1 |
| Pollard, J | 1 |
| Padia, M | 1 |
| Anderson, RJ | 1 |
| Blomqvist, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT00000487] | Phase 3 | 0 participants | Interventional | 1972-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for hydrochlorothiazide and Death, Sudden
| Article | Year |
|---|---|
Primary prevention of sudden cardiovascular death in hypertensive patients. Mortality results from the MAPHY Study.
Topics: Adult; Arteriosclerosis; Bendroflumethiazide; Death, Sudden; Diuretics; Follow-Up Studies; Humans; H | 1991 |
Ventricular ectopic activity with diuretic therapy.
Topics: Adult; Amiloride; Arrhythmias, Cardiac; Clinical Trials as Topic; Death, Sudden; Drug Combinations; | 1988 |
3 other studies available for hydrochlorothiazide and Death, Sudden
| Article | Year |
|---|---|
Myocarditis associated with methyldopa therapy.
Topics: Adult; Aged; Death, Sudden; Drug Hypersensitivity; Female; Humans; Hydrochlorothiazide; Hypertension | 1977 |
Unexpected effects of treating hypertension in men with electrocardiographic abnormalities: a critical analysis.
Topics: Adult; Arrhythmias, Cardiac; Cardiac Complexes, Premature; Cardiomegaly; Catecholamines; Chlorthalid | 1986 |
Hypertension and sudden death. Disparate effects of calcium entry blocker and diuretic therapy on cardiac dysrhythmias.
Topics: Adult; Arrhythmias, Cardiac; Calcium Channel Blockers; Cardiomegaly; Death, Sudden; Electrocardiogra | 1989 |