hydrochlorothiazide has been researched along with Cough in 18 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the incidence of cough with the angiotensin II antagonist losartan, the angiotensin converting enzyme inhibitor lisinopril, and hydrochlorothiazide in hypertensive patients with previous angiotensin converting enzyme inhibitor cough." | 9.08 | Double-blind comparison of losartan, lisinopril and hydrochlorothiazide in hypertensive patients with a previous angiotensin converting enzyme inhibitor-associated cough. ( Ramsay, LE; Yeo, WW, 1995) |
| "One hundred and thirty five non-smoking hypertensive patients with ACE inhibitor cough confirmed by lisinopril rechallenge and placebo dechallenge were recruited into a double-blind random parallel-group comparison of losartan 50 mg, lisinopril 20 mg and hydrochlorothiazide 25 mg each given once daily for a maximum of 8 weeks." | 9.08 | ACE inhibitors, angiotensin II antagonists and cough. The Losartan Cough Study Group. ( Ramsay, LE; Yeo, WW, 1995) |
| "The present study compares the occurrence of a dry, persistent cough with doses of 80 mg of valsartan, 10 mg of lisinopril, or 25 mg of hydrochlorothiazide in patients with a history of angiotensin-converting enzyme inhibitor-induced cough." | 9.08 | Valsartan, a new angiotensin II receptor antagonist: a double-blind study comparing the incidence of cough with lisinopril and hydrochlorothiazide. ( Avery, C; Benz, J; Chiang, YT; Gatlin, M; Henry, D; Oshrain, C, 1997) |
| "To compare the incidence of cough in patients with a history of angiotensin converting enzyme (ACE) inhibitor-related cough who received losartan [a type 1 angiotensin II (Ang II) receptor antagonist], lisinopril (an ACE inhibitor) or hydrochlorothiazide (a diuretic)." | 9.07 | Effects of modulators of the renin-angiotensin-aldosterone system on cough. Losartan Cough Study Group. ( Brunner, H; Dobbins, TW; Faison, EP; Irwin, R; Karlberg, BE; Lacourcière, Y; Nelson, EB; Ramsay, LE; Snavely, DB, 1994) |
| "Patients with a history of an ACE inhibitor-associated dry cough confirmed by a second challenge with lisinopril were enrolled into an international, multicenter, randomly allocated, double-blind, parallel-group, controlled trial, to be treated with losartan, lisinopril or hydrochlorothiazide." | 9.07 | Association between cough and angiotensin converting enzyme inhibitors versus angiotensin II antagonists: the design of a prospective, controlled study. ( Faison, EP; Lacourcière, Y; Lefebvre, J; Nakhle, G; Nelson, EB; Snavely, DB, 1994) |
| "Eprosartan is an angiotensin II receptor antagonist (angiotensin II receptor blocker [ARB]) used in the treatment of hypertension." | 8.85 | Eprosartan: a review of its use in hypertension. ( Plosker, GL, 2009) |
| "The effect of hydrochlorothiazide, a diuretic which is used in the treatment not only of edema but also of hypertension, on coughs associated with treatment with enalapril was studied in guinea pigs." | 7.68 | The effect of hydrochlorothiazide on the enhanced coughing associated with treatment with enalapril. ( Kamei, J; Kasuya, Y, 1992) |
| " Dosage could be increased for both telmisartan (40 --> 80 --> 160 mg) and lisinopril (10 --> 20 --> 40 mg) at each of the first 2 monthly visits if DBP control (<90 mm Hg) had not been established." | 6.69 | Comparison of telmisartan with lisinopril in patients with mild-to-moderate hypertension. ( Frishman, WH; Guthrie, G; Neutel, JM; Oparil, S; Papademitriou, V, 1999) |
| "1%) were the clinical adverse experiences most often reported in patients treated with losartan." | 6.68 | Safety and tolerability of losartan potassium, an angiotensin II receptor antagonist, compared with hydrochlorothiazide, atenolol, felodipine ER, and angiotensin-converting enzyme inhibitors for the treatment of systemic hypertension. ( Dunlay, MC; Goldberg, AI; Sweet, CS, 1995) |
| "To compare the incidence of cough with the angiotensin II antagonist losartan, the angiotensin converting enzyme inhibitor lisinopril, and hydrochlorothiazide in hypertensive patients with previous angiotensin converting enzyme inhibitor cough." | 5.08 | Double-blind comparison of losartan, lisinopril and hydrochlorothiazide in hypertensive patients with a previous angiotensin converting enzyme inhibitor-associated cough. ( Ramsay, LE; Yeo, WW, 1995) |
| "One hundred and thirty five non-smoking hypertensive patients with ACE inhibitor cough confirmed by lisinopril rechallenge and placebo dechallenge were recruited into a double-blind random parallel-group comparison of losartan 50 mg, lisinopril 20 mg and hydrochlorothiazide 25 mg each given once daily for a maximum of 8 weeks." | 5.08 | ACE inhibitors, angiotensin II antagonists and cough. The Losartan Cough Study Group. ( Ramsay, LE; Yeo, WW, 1995) |
| "The present study compares the occurrence of a dry, persistent cough with doses of 80 mg of valsartan, 10 mg of lisinopril, or 25 mg of hydrochlorothiazide in patients with a history of angiotensin-converting enzyme inhibitor-induced cough." | 5.08 | Valsartan, a new angiotensin II receptor antagonist: a double-blind study comparing the incidence of cough with lisinopril and hydrochlorothiazide. ( Avery, C; Benz, J; Chiang, YT; Gatlin, M; Henry, D; Oshrain, C, 1997) |
| "To compare the incidence of cough in patients with a history of angiotensin converting enzyme (ACE) inhibitor-related cough who received losartan [a type 1 angiotensin II (Ang II) receptor antagonist], lisinopril (an ACE inhibitor) or hydrochlorothiazide (a diuretic)." | 5.07 | Effects of modulators of the renin-angiotensin-aldosterone system on cough. Losartan Cough Study Group. ( Brunner, H; Dobbins, TW; Faison, EP; Irwin, R; Karlberg, BE; Lacourcière, Y; Nelson, EB; Ramsay, LE; Snavely, DB, 1994) |
| "Patients with a history of an ACE inhibitor-associated dry cough confirmed by a second challenge with lisinopril were enrolled into an international, multicenter, randomly allocated, double-blind, parallel-group, controlled trial, to be treated with losartan, lisinopril or hydrochlorothiazide." | 5.07 | Association between cough and angiotensin converting enzyme inhibitors versus angiotensin II antagonists: the design of a prospective, controlled study. ( Faison, EP; Lacourcière, Y; Lefebvre, J; Nakhle, G; Nelson, EB; Snavely, DB, 1994) |
| "Eprosartan is an angiotensin II receptor antagonist (angiotensin II receptor blocker [ARB]) used in the treatment of hypertension." | 4.85 | Eprosartan: a review of its use in hypertension. ( Plosker, GL, 2009) |
| "We observed that our Chinese group was more than twice as likely as the general population to discontinue lisinopril due to cough, controlling for the influence of sex, age, and smoking." | 3.76 | Angiotensin-converting enzyme-related cough among Chinese-Americans. ( Coates, AO; Kwong, J; Rezvani, F; Tseng, DS, 2010) |
| "The effect of hydrochlorothiazide, a diuretic which is used in the treatment not only of edema but also of hypertension, on coughs associated with treatment with enalapril was studied in guinea pigs." | 3.68 | The effect of hydrochlorothiazide on the enhanced coughing associated with treatment with enalapril. ( Kamei, J; Kasuya, Y, 1992) |
| "The effects of nebulized diuretics on citric acid-induced cough and airway obstruction in guinea pigs and capsaicin-induced cough and increase in airway resistance in humans have been studied." | 3.68 | A comparison of the effect of inhaled diuretics on airway reflexes in humans and guinea pigs. ( Choudry, NB; Fuller, RW; Karlsson, JA; Zackrisson, C, 1992) |
| " Dosage could be increased for both telmisartan (40 --> 80 --> 160 mg) and lisinopril (10 --> 20 --> 40 mg) at each of the first 2 monthly visits if DBP control (<90 mm Hg) had not been established." | 2.69 | Comparison of telmisartan with lisinopril in patients with mild-to-moderate hypertension. ( Frishman, WH; Guthrie, G; Neutel, JM; Oparil, S; Papademitriou, V, 1999) |
| "1%) were the clinical adverse experiences most often reported in patients treated with losartan." | 2.68 | Safety and tolerability of losartan potassium, an angiotensin II receptor antagonist, compared with hydrochlorothiazide, atenolol, felodipine ER, and angiotensin-converting enzyme inhibitors for the treatment of systemic hypertension. ( Dunlay, MC; Goldberg, AI; Sweet, CS, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.11) | 18.7374 |
| 1990's | 14 (77.78) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ramsay, LE | 3 |
| Yeo, WW | 2 |
| Plosker, GL | 1 |
| Tseng, DS | 1 |
| Kwong, J | 1 |
| Rezvani, F | 1 |
| Coates, AO | 1 |
| Wenger, TL | 1 |
| Dohrmann, ML | 1 |
| Strauss, HC | 1 |
| Conley, MJ | 1 |
| Wechsler, AS | 1 |
| Wagner, GS | 1 |
| Lacourcière, Y | 2 |
| Brunner, H | 1 |
| Irwin, R | 1 |
| Karlberg, BE | 1 |
| Snavely, DB | 2 |
| Dobbins, TW | 1 |
| Faison, EP | 2 |
| Nelson, EB | 2 |
| Goldberg, AI | 2 |
| Dunlay, MC | 1 |
| Sweet, CS | 2 |
| Lefebvre, J | 1 |
| Nakhle, G | 1 |
| Weidmann, B | 1 |
| Hänseler, T | 1 |
| Jansen, W | 1 |
| Geppert, R | 1 |
| Mathas, B | 1 |
| Tauchert, M | 1 |
| Ruilope, LM | 1 |
| Simpson, RL | 1 |
| Toh, J | 1 |
| Arcuri, KE | 1 |
| Benz, J | 1 |
| Oshrain, C | 1 |
| Henry, D | 1 |
| Avery, C | 1 |
| Chiang, YT | 1 |
| Gatlin, M | 1 |
| Breithaupt-Grögler, K | 1 |
| Gerhardt, G | 1 |
| Lehmann, G | 1 |
| Notter, T | 1 |
| Belz, GG | 1 |
| Elliott, WJ | 1 |
| Neutel, JM | 1 |
| Frishman, WH | 1 |
| Oparil, S | 1 |
| Papademitriou, V | 1 |
| Guthrie, G | 1 |
| Kamei, J | 1 |
| Kasuya, Y | 1 |
| Karlsson, JA | 1 |
| Choudry, NB | 1 |
| Zackrisson, C | 1 |
| Fuller, RW | 1 |
| Sebastian, JL | 1 |
| McKinney, WP | 1 |
| Kaufman, J | 1 |
| Young, MJ | 1 |
| Casadio, S | 1 |
| Bruzzese, T | 1 |
| Pala, G | 1 |
| Coppi, G | 1 |
| Turba, C | 1 |
2 reviews available for hydrochlorothiazide and Cough
| Article | Year |
|---|---|
Eprosartan: a review of its use in hypertension.
Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Body Ma | 2009 |
[Congenitally corrected transposition of the great vessels in adulthood. The value of noninvasive study methods].
Topics: Captopril; Cardiac Catheterization; Cough; Diagnosis, Differential; Drug Therapy, Combination; Dyspn | 1994 |
11 trials available for hydrochlorothiazide and Cough
| Article | Year |
|---|---|
Double-blind comparison of losartan, lisinopril and hydrochlorothiazide in hypertensive patients with a previous angiotensin converting enzyme inhibitor-associated cough.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Cough; Diuretics; | 1995 |
Effects of modulators of the renin-angiotensin-aldosterone system on cough. Losartan Cough Study Group.
Topics: Adult; Aged; Angiotensin Receptor Antagonists; Biphenyl Compounds; Cough; Double-Blind Method; Femal | 1994 |
Safety and tolerability of losartan potassium, an angiotensin II receptor antagonist, compared with hydrochlorothiazide, atenolol, felodipine ER, and angiotensin-converting enzyme inhibitors for the treatment of systemic hypertension.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Conver | 1995 |
Association between cough and angiotensin converting enzyme inhibitors versus angiotensin II antagonists: the design of a prospective, controlled study.
Topics: Adult; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Cough; Double-Blind Method; Fema | 1994 |
ACE inhibitors, angiotensin II antagonists and cough. The Losartan Cough Study Group.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; | 1995 |
Controlled trial of losartan given concomitantly with different doses of hydrochlorothiazide in hypertensive patients.
Topics: Adult; Antihypertensive Agents; Asthenia; Biphenyl Compounds; Blood Pressure; Controlled Clinical Tr | 1996 |
Valsartan, a new angiotensin II receptor antagonist: a double-blind study comparing the incidence of cough with lisinopril and hydrochlorothiazide.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; | 1997 |
Blood pressure and aortic elastic properties--verapamil SR/trandolapril compared to a metoprolol/hydrochlorothiazide combination therapy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive | 1998 |
Double-blind comparison of eprosartan and enalapril on cough and blood pressure in unselected hypertensive patients. Eprosartan Study Group.
Topics: Acrylates; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cough; | 1999 |
Comparison of telmisartan with lisinopril in patients with mild-to-moderate hypertension.
Topics: Angioedema; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzo | 1999 |
Angiotensin-converting enzyme inhibitors and cough. Prevalence in an outpatient medical clinic population.
Topics: Ambulatory Care; Angiotensin-Converting Enzyme Inhibitors; Cough; Cross-Sectional Studies; Humans; H | 1991 |
5 other studies available for hydrochlorothiazide and Cough
| Article | Year |
|---|---|
Angiotensin-converting enzyme-related cough among Chinese-Americans.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Asian; California; Cohort S | 2010 |
Hypersensitive carotid sinus syndrome manifested as cough syncope.
Topics: Blood Pressure; Bradycardia; Cardiac Pacing, Artificial; Carotid Sinus; Cough; Denervation; Electroc | 1980 |
The effect of hydrochlorothiazide on the enhanced coughing associated with treatment with enalapril.
Topics: Animals; Capsaicin; Cough; Dose-Response Relationship, Drug; Enalapril; Guinea Pigs; Hydrochlorothia | 1992 |
A comparison of the effect of inhaled diuretics on airway reflexes in humans and guinea pigs.
Topics: Administration, Inhalation; Adult; Airway Obstruction; Airway Resistance; Animals; Capsaicin; Citrat | 1992 |
Hypoglycemic activity and pharmacological picture of 4-(1-naphthyl)butylamine derivatives.
Topics: Acetylcholine; Animals; Atropine; Behavior, Animal; Blood Glucose; Blood Pressure; Butylamines; Chem | 1966 |