hydrochlorothiazide has been researched along with Chronic Illness in 53 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of this study was to elucidate whether hydrochlorothiazide additionally exerts such effects in stroke patients under treatment with losartan." | 9.20 | Effects of hydrochlorothiazide on oxidative stress and pulse pressure in hypertensive patients with chronic stroke: the EMINENT study. ( Ago, T; Hata, J; Ibayashi, S; Kamouchi, M; Kitazono, T; Kusuda, K; Nagao, T; Nakane, H; Omae, T, 2015) |
| "Furosemide is the diuretic of choice for the treatment of hypertension in chronic kidney disease but the adaptative changes in the distal nephron may decrease its efficacy." | 9.16 | A pilot study comparing furosemide and hydrochlorothiazide in patients with hypertension and stage 4 or 5 chronic kidney disease. ( Berland, Y; Dussol, B; Morange, S; Moussi-Frances, J; Mundler, O; Somma-Delpero, C, 2012) |
| "We studied the synergism between high-dose furosemide and hydrochlorothiazide in patients with severe congestive heart failure and impaired renal function showing diuretic resistance to a daily dose of furosemide of at least 250 mg." | 9.08 | Combination of high-dose furosemide and hydrochlorothiazide in the treatment of refractory congestive heart failure. ( Dormans, TP; Gerlag, PG, 1996) |
| "In a randomized and double-blind study of 116 patients with chronic heart failure (NYHA classes II or III) the effectiveness of captopril + hydrochlorothiazide (HCT) (group 1) and of digoxin + HCT (group 2) were compared." | 9.06 | [Captopril versus digoxin in the treatment of mild to moderately severe heart failure]. ( Esser, H; Heck, I; Lüderitz, B; Müller, HM, 1989) |
| "The efficacy of flosequinan 100 mg once daily was evaluated in 15 patients with severe congestive heart failure (New York Heart Association [NYHA] class II-IV) who had not responded adequately to digoxin and diuretics." | 7.68 | A non-invasive evaluation of flosequinan on haemodynamics and exercise capacity in chronic congestive heart failure. ( Feinberg, MS; Freimark, D; King, C; Motro, M; Schneeweiss, A; Wynne, RD, 1993) |
| "Thirty two patients with essential hypertension, stage I and II according to WHO classification, were treated according to the following schedule: period A--3 X 1 dragée placebo--3 weeks; period B--3 X 1 dragée placebo + 25 mg hydrochlorothiazide in the morning--6 weeks; period C--3 X 1 dragée isoptin 80 mg + 25 mg hydrochlorothiazide in the morning--6 weeks; period D--3 X 1 dragée placebo--2 weeks." | 7.67 | [Treatment of essential hypertension (hypertensive disease) with verapamil and hydrochlorothiazide]. ( Dimitrov, D, 1985) |
| " The aim of this study was to elucidate whether hydrochlorothiazide additionally exerts such effects in stroke patients under treatment with losartan." | 5.20 | Effects of hydrochlorothiazide on oxidative stress and pulse pressure in hypertensive patients with chronic stroke: the EMINENT study. ( Ago, T; Hata, J; Ibayashi, S; Kamouchi, M; Kitazono, T; Kusuda, K; Nagao, T; Nakane, H; Omae, T, 2015) |
| "Furosemide is the diuretic of choice for the treatment of hypertension in chronic kidney disease but the adaptative changes in the distal nephron may decrease its efficacy." | 5.16 | A pilot study comparing furosemide and hydrochlorothiazide in patients with hypertension and stage 4 or 5 chronic kidney disease. ( Berland, Y; Dussol, B; Morange, S; Moussi-Frances, J; Mundler, O; Somma-Delpero, C, 2012) |
| "0] g/24 h proteinuria) were treated during 6-week periods with placebo, ARB (100 mg/d losartan), and ARB plus diuretics (100 mg/d losartan plus 25 mg/d hydrochlorothiazide) combined with consecutively regular and low sodium diets (193 ± 62 versus 93 ± 52 mmol Na(+)/d)." | 5.15 | Effects of antiproteinuric intervention on elevated connective tissue growth factor (CTGF/CCN-2) plasma and urine levels in nondiabetic nephropathy. ( Goldschmeding, R; Hemmelder, MH; Laverman, GD; Navis, G; Nguyen, TQ; Slagman, MC; Vogt, L; Waanders, F, 2011) |
| "Urinary KIM-1 level was increased in patients with nondiabetic CKD with proteinuria and decreased in parallel with proteinuria by using losartan, sodium restriction, their combination, losartan plus HCT, and the latter plus sodium restriction." | 5.14 | Effect of renin-angiotensin-aldosterone system inhibition, dietary sodium restriction, and/or diuretics on urinary kidney injury molecule 1 excretion in nondiabetic proteinuric kidney disease: a post hoc analysis of a randomized controlled trial. ( Bonventre, JV; Damman, K; Hamming, I; Leuvenink, H; Navis, G; Vaidya, VS; van Goor, H; Vogt, L; Waanders, F, 2009) |
| "We studied the synergism between high-dose furosemide and hydrochlorothiazide in patients with severe congestive heart failure and impaired renal function showing diuretic resistance to a daily dose of furosemide of at least 250 mg." | 5.08 | Combination of high-dose furosemide and hydrochlorothiazide in the treatment of refractory congestive heart failure. ( Dormans, TP; Gerlag, PG, 1996) |
| "The authors made an open-comparative trial of fosinopril (Fosinorm) efficacy and tolerability in 20 patients (9 males and 11 females) with stage II mild and moderate essential hypertension accompanied with disturbed glucose tolerance and dyslipidemia." | 5.08 | [Fosinorm in the treatment of essential hypertension with a metabolic syndrome]. ( Drozdov, VN; Ivleva, AIa; Kobalava, ZhD; Kotovskaia, IuV; Moiseev, VS; Moryleva, ON, 1997) |
| "In a randomized and double-blind study of 116 patients with chronic heart failure (NYHA classes II or III) the effectiveness of captopril + hydrochlorothiazide (HCT) (group 1) and of digoxin + HCT (group 2) were compared." | 5.06 | [Captopril versus digoxin in the treatment of mild to moderately severe heart failure]. ( Esser, H; Heck, I; Lüderitz, B; Müller, HM, 1989) |
| "Sixteen patients in heart failure and sinus rhythm were, after a four-week treatment-free period, randomly assigned to receive, for four to six weeks, either a diuretic combination (hydrochlorothiazide + triamterene) or a digitalis glycoside." | 5.06 | [Basic therapy of chronic heart failure with digitalis or diuretics?]. ( Bussmann, WD; Hopf, R; Kaltenbach, M; Offermann, T; Sievert, H, 1989) |
| "25 mg of hydrochlorothiazide, the clinical condition, the daily profile of blood pressure, body adrenoreactivity structural and functional parameters of the left ventricle in 28 pregnant women with preeclampsia in the background chronic hypertension (hypertension stage II, 2 nd degree) and 28 pregnant women with preeclampsia and mild to moderate severity in terms of 22-28 weeks of pregnancy." | 3.78 | [Combined low-dose antihypertensive therapy in pregnant women with hypertension and preeclampsia]. ( Manukhin, IB; Markova, EV; Markova, LI; Striuk, RI, 2012) |
| "The efficacy of flosequinan 100 mg once daily was evaluated in 15 patients with severe congestive heart failure (New York Heart Association [NYHA] class II-IV) who had not responded adequately to digoxin and diuretics." | 3.68 | A non-invasive evaluation of flosequinan on haemodynamics and exercise capacity in chronic congestive heart failure. ( Feinberg, MS; Freimark, D; King, C; Motro, M; Schneeweiss, A; Wynne, RD, 1993) |
| "Thirty two patients with essential hypertension, stage I and II according to WHO classification, were treated according to the following schedule: period A--3 X 1 dragée placebo--3 weeks; period B--3 X 1 dragée placebo + 25 mg hydrochlorothiazide in the morning--6 weeks; period C--3 X 1 dragée isoptin 80 mg + 25 mg hydrochlorothiazide in the morning--6 weeks; period D--3 X 1 dragée placebo--2 weeks." | 3.67 | [Treatment of essential hypertension (hypertensive disease) with verapamil and hydrochlorothiazide]. ( Dimitrov, D, 1985) |
| " The drug is particularly useful in patients with chronic gouty arthritis and tophi, either refractory or allergic to probenecid, sulfinpyrazone, or allopurinol." | 3.65 | Pharmacokinetic and clinical studies of a new uricosuric agent - benzbromarone. ( Yu, TF, 1976) |
| "CLOROTIC is the first large-scale trial to evaluate whether the addition of a thiazide diuretic (hydrochlorothiazide) to a loop diuretic (furosemide) is a safe and effective strategy for improving congestive symptoms resulting from HF." | 2.82 | Rationale and Design of the "Safety and Efficacy of the Combination of Loop with Thiazide-type Diuretics in Patients with Decompensated Heart Failure (CLOROTIC) Trial:" A Double-Blind, Randomized, Placebo-Controlled Study to Determine the Effect of Combin ( Casado, J; Formiga, F; Freitas Ramírez, A; Manzano, L; Morales-Rull, JL; Trullàs, JC, 2016) |
| "Insulin resistance is associated with a number of risk factors for atherosclerosis, including glucose intolerance, hypertension, and dyslipidemia." | 2.38 | Insulin resistance. An often unrecognized problem accompanying chronic medical disorders. ( Bell, DS, 1993) |
| "Although the diagnosis of Gitelman syndrome (GS) and Bartter syndrome (BS) is now feasible by genetic analysis, implementation of genetic testing for these disorders is still hampered by several difficulties, including large gene dimensions, lack of hot-spot mutations, heavy workup time, and costs." | 1.34 | A thiazide test for the diagnosis of renal tubular hypokalemic disorders. ( Bettinelli, A; Bianchetti, MG; Borsa, N; Casari, G; Colussi, G; De Ferrari, ME; Mattiello, C; Syrén, ML; Tedeschi, S, 2007) |
| "Hydrochlorothiazide treatment in hypercalciuric and osteoporotic men was associated with a rapid rebound increase in bone mineral density." | 1.30 | Rapid recovery of bone mass in hypercalciuric, osteoporotic men treated with hydrochlorothiazide. ( Adams, JS; Kantorovich, V; Song, CF, 1999) |
| "A total of 127 patients with bronchial asthma of infectious-allergic genesis and chronic obstructive bronchitis were examined for the central and regional hemodynamics as well as for the blood levels of serotonin and monoamine oxidase." | 1.27 | [Arterial hypertension in chronic bronchial obstruction and various problems of its treatment]. ( Bobrov, VA; Fushteĭ, IM; Ianushevskaia, TA; Polipova, SN, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (43.40) | 18.7374 |
| 1990's | 9 (16.98) | 18.2507 |
| 2000's | 10 (18.87) | 29.6817 |
| 2010's | 11 (20.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kar, SK | 1 |
| Srivastava, A | 1 |
| Nakane, H | 1 |
| Kamouchi, M | 1 |
| Hata, J | 1 |
| Ibayashi, S | 1 |
| Kusuda, K | 1 |
| Omae, T | 1 |
| Nagao, T | 1 |
| Ago, T | 1 |
| Kitazono, T | 1 |
| Trullàs, JC | 1 |
| Morales-Rull, JL | 1 |
| Casado, J | 1 |
| Freitas Ramírez, A | 1 |
| Manzano, L | 1 |
| Formiga, F | 1 |
| Waanders, F | 2 |
| Vaidya, VS | 1 |
| van Goor, H | 1 |
| Leuvenink, H | 1 |
| Damman, K | 1 |
| Hamming, I | 1 |
| Bonventre, JV | 1 |
| Vogt, L | 2 |
| Navis, G | 3 |
| Renke, M | 2 |
| Tylicki, L | 2 |
| Knap, N | 1 |
| Rutkowski, P | 2 |
| Neuwelt, A | 1 |
| Larczynski, W | 2 |
| Wozniak, M | 1 |
| Rutkowski, B | 2 |
| Perico, N | 1 |
| Cattaneo, D | 1 |
| Remuzzi, G | 1 |
| Abe, M | 2 |
| Okada, K | 2 |
| Maruyama, T | 2 |
| Matsumoto, K | 2 |
| Thornton, SN | 1 |
| Malekzadeh, F | 1 |
| Marshall, T | 1 |
| Pourshams, A | 1 |
| Gharravi, M | 1 |
| Aslani, A | 1 |
| Nateghi, A | 1 |
| Rastegarpanah, M | 1 |
| Khoshnia, M | 1 |
| Semnani, S | 1 |
| Salahi, R | 1 |
| Thomas, GN | 1 |
| Larijani, B | 1 |
| Cheng, KK | 1 |
| Malekzadeh, R | 1 |
| Slagman, MC | 2 |
| Laverman, GD | 2 |
| Fanelli, C | 1 |
| Fernandes, BH | 1 |
| Machado, FG | 1 |
| Okabe, C | 1 |
| Malheiros, DM | 1 |
| Fujihara, CK | 1 |
| Zatz, R | 1 |
| Nguyen, TQ | 1 |
| Hemmelder, MH | 1 |
| Goldschmeding, R | 1 |
| Suzuki, O | 1 |
| Ishii, H | 1 |
| Kobayashi, S | 1 |
| Dussol, B | 1 |
| Moussi-Frances, J | 1 |
| Morange, S | 1 |
| Somma-Delpero, C | 1 |
| Mundler, O | 1 |
| Berland, Y | 1 |
| Manukhin, IB | 1 |
| Markova, EV | 1 |
| Markova, LI | 1 |
| Striuk, RI | 1 |
| Ogata, S | 1 |
| Sharyo, S | 1 |
| Hinman, DJ | 1 |
| Manabe, S | 1 |
| Minutolo, R | 1 |
| De Nicola, L | 1 |
| Zamboli, P | 1 |
| Chiodini, P | 1 |
| Signoriello, G | 1 |
| Toderico, C | 1 |
| Arfè, G | 1 |
| Boschi, G | 1 |
| Brancati, C | 1 |
| Iaccarino, P | 1 |
| Conte, G | 1 |
| Finimundi, HC | 1 |
| Caramori, PA | 1 |
| Parker, JD | 2 |
| Colussi, G | 1 |
| Bettinelli, A | 1 |
| Tedeschi, S | 1 |
| De Ferrari, ME | 1 |
| Syrén, ML | 1 |
| Borsa, N | 1 |
| Mattiello, C | 1 |
| Casari, G | 1 |
| Bianchetti, MG | 1 |
| Aleksandrowicz, E | 1 |
| Lysiak-Szydlowska, W | 1 |
| Zipes, DP | 1 |
| Orgain, ES | 1 |
| Rames, I | 1 |
| Kristufek, V | 1 |
| Eninia, GI | 1 |
| Smeltere, ES | 1 |
| Godlevska, MA | 1 |
| Uzulinia, IP | 1 |
| Shvedenko, LA | 1 |
| Parashchak, AP | 1 |
| Iurkevich, ST | 1 |
| Neporadnyĭ, MD | 1 |
| Bigar', PV | 1 |
| Bell, DS | 1 |
| Motro, M | 1 |
| Freimark, D | 1 |
| Feinberg, MS | 1 |
| Wynne, RD | 1 |
| King, C | 1 |
| Schneeweiss, A | 1 |
| Parker, AB | 1 |
| Farrell, B | 1 |
| Parker, JO | 1 |
| Dormans, TP | 1 |
| Gerlag, PG | 1 |
| Kobalava, ZhD | 1 |
| Kotovskaia, IuV | 1 |
| Moryleva, ON | 1 |
| Drozdov, VN | 1 |
| Ivleva, AIa | 1 |
| Moiseev, VS | 1 |
| Stepan, VM | 1 |
| Hammer, HF | 1 |
| Krejs, GJ | 1 |
| Adams, JS | 1 |
| Song, CF | 1 |
| Kantorovich, V | 1 |
| Sidorenko, BA | 1 |
| Kharchenko, VI | 1 |
| Evsikov, EM | 1 |
| Arias, F | 1 |
| Zamora, J | 1 |
| Yu, TF | 1 |
| Zamotaev, IP | 1 |
| Kabanov, AI | 1 |
| Dodek, A | 1 |
| Burg, JR | 1 |
| Kloster, FR | 1 |
| Tomashets, EA | 1 |
| Mazur, NA | 1 |
| Masenko, VP | 1 |
| Podszus, Th | 1 |
| Peter, JH | 1 |
| Völger, KD | 1 |
| Zilles, P | 1 |
| Heck, I | 1 |
| Müller, HM | 1 |
| Esser, H | 1 |
| Lüderitz, B | 1 |
| Sievert, H | 1 |
| Offermann, T | 1 |
| Hopf, R | 1 |
| Kaltenbach, M | 1 |
| Bussmann, WD | 1 |
| Nartowicz, E | 1 |
| Burduk, P | 1 |
| Karwowski, J | 1 |
| Wu, SC | 1 |
| Secchi, MB | 1 |
| Mancarella, S | 1 |
| Bettazzi, L | 1 |
| Civelli, M | 1 |
| Cirò, A | 1 |
| Oltrona, L | 1 |
| Folli, G | 1 |
| Bobrov, VA | 1 |
| Polipova, SN | 1 |
| Fushteĭ, IM | 1 |
| Ianushevskaia, TA | 1 |
| Robinson, HN | 1 |
| Morison, WL | 1 |
| Hood, AF | 1 |
| Dimitrov, D | 1 |
| Schiffl, H | 1 |
| Schollmeyer, P | 1 |
| Green, RA | 1 |
| Farrow, CS | 1 |
| Spach, MO | 1 |
| Bloch, R | 1 |
| Velly, J | 1 |
| Imbs, JL | 1 |
| Bousquet, P | 1 |
| Schwartz, J | 1 |
| Ar'eva, EM | 1 |
| Iaroshevskiĭ, AIa | 1 |
| Saito, T | 1 |
| Yoshida, S | 1 |
| Nakao, K | 1 |
| Takanashi, R | 1 |
| Schneider, PJ | 1 |
| Eytel, CS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Safety and Efficacy of the Combination of Loop Diuretics With Thiazide-type Diuretics in Patients With Decompensated Heart Failure: a Double-blind, Randomized, Placebo-controlled Trial (CLOROTIC Trial).[NCT01647932] | Phase 3 | 232 participants (Actual) | Interventional | 2014-10-31 | Completed | ||
| Fixed Combination for Lipid and Blood Pressure Control. Randomized Cross-over Study[NCT03047538] | Phase 4 | 0 participants (Actual) | Interventional | 2017-09-01 | Withdrawn (stopped due to Insufficient funds) | ||
| Effectiveness of Polypill for Primary Prevention of Cardiovascular Disease (PolyPars): Study Design and Rationale for a Pragmatic Cluster Randomized Controlled Trial[NCT03459560] | Phase 3 | 4,415 participants (Actual) | Interventional | 2015-12-20 | Active, not recruiting | ||
| Fixed-dose Combination Therapy (PolyPill) in Primary and Secondary Prevention of Cardiovascular Disease in Middle-aged and Elderly Iranians[NCT01271985] | Phase 3 | 8,410 participants (Actual) | Interventional | 2011-02-28 | Completed | ||
| DD-study: Diet or Diuretics for Salt-sensitivity in Chronic Kidney Disease[NCT02875886] | Phase 4 | 28 participants (Actual) | Interventional | 2016-09-30 | Completed | ||
| Chlortalidone and Bumetanide in Advanced Chronic Kidney Disease: HEBE-CKD Trial[NCT03923933] | Phase 2 | 34 participants (Actual) | Interventional | 2019-06-18 | Completed | ||
| Comparative Randomized Single-blind Trial of Amiloride in Coronary Heart Disease[NCT01231165] | Phase 2/Phase 3 | 70 participants (Actual) | Interventional | 2009-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | mmHg (Mean) |
|---|---|
| Placebo | -3.4 |
| Treatment Grup | -13.5 |
Decrease in extracellular water measured by bioelectrical impedance analysis (NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | litres (Mean) |
|---|---|
| Placebo | -0.15 |
| Treatment Grup | 2.55 |
Decrease in extracellular water / total body water ratio measured by bioelectrical impedance analysis (NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | percentage of ECW/TBW (Mean) |
|---|---|
| Placebo | -0.24 |
| Treatment Grup | -2.92 |
decrease in blood pressure compared wit baseline measure (mmhg) (NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | mmHg (Mean) |
|---|---|
| Placebo | -5.4 |
| Treatment Grup | -18.1 |
(NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | mmHg (Mean) |
|---|---|
| Placebo | -10 |
| Treatment Grup | -26.1 |
Increase in the fractional excretion of sodium compared with the baseline measure (NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | percentage of sodium excreted (Mean) |
|---|---|
| Placebo | -0.348 |
| Treatment Grup | 0.598 |
Measured by bioelectrical impedance analysis, compared to the initial measurement (NCT03923933)
Timeframe: Change from Basal to day 28
| Intervention | litres (Mean) |
|---|---|
| Placebo | -0.075 |
| Treatment Grup | -4.36 |
1 review available for hydrochlorothiazide and Chronic Illness
| Article | Year |
|---|---|
Insulin resistance. An often unrecognized problem accompanying chronic medical disorders.
Topics: Acanthosis Nigricans; Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Arteri | 1993 |
19 trials available for hydrochlorothiazide and Chronic Illness
| Article | Year |
|---|---|
Effects of hydrochlorothiazide on oxidative stress and pulse pressure in hypertensive patients with chronic stroke: the EMINENT study.
Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive A | 2015 |
Rationale and Design of the "Safety and Efficacy of the Combination of Loop with Thiazide-type Diuretics in Patients with Decompensated Heart Failure (CLOROTIC) Trial:" A Double-Blind, Randomized, Placebo-Controlled Study to Determine the Effect of Combin
Topics: Chronic Disease; Diuretics; Double-Blind Method; Drug Therapy, Combination; Drug Tolerance; Furosemi | 2016 |
Effect of renin-angiotensin-aldosterone system inhibition, dietary sodium restriction, and/or diuretics on urinary kidney injury molecule 1 excretion in nondiabetic proteinuric kidney disease: a post hoc analysis of a randomized controlled trial.
Topics: Acetylglucosaminidase; Adult; Aged; Antihypertensive Agents; Biomarkers; Chronic Disease; Combined M | 2009 |
Spironolactone attenuates oxidative stress in patients with chronic kidney disease.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antioxidan | 2008 |
Renoprotect and blood pressure lowering effect of low-dose hydrochlorothiazide added to intensive renin-angiotensin inhibition in hypertensive patients with chronic kidney disease.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihyperte | 2009 |
Antiproteinuric and blood pressure-lowering effects of a fixed-dose combination of losartan and hydrochlorothiazide in hypertensive patients with stage 3 chronic kidney disease.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Chronic Disease; Creatinine; Dose-Response Relationsh | 2009 |
A pilot double-blind randomised placebo-controlled trial of the effects of fixed-dose combination therapy ('polypill') on cardiovascular risk factors.
Topics: Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressure; Card | 2010 |
A pilot double-blind randomised placebo-controlled trial of the effects of fixed-dose combination therapy ('polypill') on cardiovascular risk factors.
Topics: Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressure; Card | 2010 |
A pilot double-blind randomised placebo-controlled trial of the effects of fixed-dose combination therapy ('polypill') on cardiovascular risk factors.
Topics: Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressure; Card | 2010 |
A pilot double-blind randomised placebo-controlled trial of the effects of fixed-dose combination therapy ('polypill') on cardiovascular risk factors.
Topics: Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressure; Card | 2010 |
A pilot double-blind randomised placebo-controlled trial of the effects of fixed-dose combination therapy ('polypill') on cardiovascular risk factors.
Topics: Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressure; Card | 2010 |
A pilot double-blind randomised placebo-controlled trial of the effects of fixed-dose combination therapy ('polypill') on cardiovascular risk factors.
Topics: Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressure; Card | 2010 |
A pilot double-blind randomised placebo-controlled trial of the effects of fixed-dose combination therapy ('polypill') on cardiovascular risk factors.
Topics: Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressure; Card | 2010 |
A pilot double-blind randomised placebo-controlled trial of the effects of fixed-dose combination therapy ('polypill') on cardiovascular risk factors.
Topics: Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressure; Card | 2010 |
A pilot double-blind randomised placebo-controlled trial of the effects of fixed-dose combination therapy ('polypill') on cardiovascular risk factors.
Topics: Aged; Anticholesteremic Agents; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressure; Card | 2010 |
Effects of antiproteinuric intervention on elevated connective tissue growth factor (CTGF/CCN-2) plasma and urine levels in nondiabetic nephropathy.
Topics: Angiotensin II Type 1 Receptor Blockers; Biomarkers; Chronic Disease; Combined Modality Therapy; Con | 2011 |
A pilot study comparing furosemide and hydrochlorothiazide in patients with hypertension and stage 4 or 5 chronic kidney disease.
Topics: Aged; Anthropology; Biological Availability; Blood Pressure; Chronic Disease; Diet Records; Diuretic | 2012 |
Effect of diuretic therapy on exercise capacity in patients with chronic angina and preserved left ventricular function.
Topics: Aged; Amiloride; Angina Pectoris; Blood Pressure; Chronic Disease; Diuretics; Double-Blind Method; D | 2007 |
Triple pharmacological blockade of the renin-angiotensin-aldosterone system in nondiabetic CKD: an open-label crossover randomized controlled trial.
Topics: Acetylglucosaminidase; Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme | 2008 |
[Effect of different saluretics on carbohydrate metabolism and blood pressure behavior in diabetics].
Topics: Acetazolamide; Aged; Blood Glucose; Blood Pressure; Carbohydrate Metabolism; Chronic Disease; Clinic | 1984 |
Effects of diuretic therapy on the development of tolerance to nitroglycerin and exercise capacity in patients with chronic stable angina.
Topics: Administration, Cutaneous; Amiloride; Angina Pectoris; Blood Pressure; Chronic Disease; Cross-Over S | 1996 |
Combination of high-dose furosemide and hydrochlorothiazide in the treatment of refractory congestive heart failure.
Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Diuretics; Dose-Response Relationship, Drug; Drug S | 1996 |
[Fosinorm in the treatment of essential hypertension with a metabolic syndrome].
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Chronic Disease; Diuretics; Drug | 1997 |
[Therapeutic use of amiloride and its combinations with hydrochlorothiazide and furosemide in chronic circulatory insufficiency].
Topics: Adult; Aged; Amiloride; Cardiovascular Diseases; Chronic Disease; Clinical Trials as Topic; Diuresis | 1978 |
[Captopril versus digoxin in the treatment of mild to moderately severe heart failure].
Topics: Blood Pressure; Captopril; Chronic Disease; Clinical Trials as Topic; Digoxin; Double-Blind Method; | 1989 |
[Basic therapy of chronic heart failure with digitalis or diuretics?].
Topics: Aged; Chronic Disease; Digitalis Glycosides; Digitoxin; Digoxin; Drug Combinations; Drug Evaluation; | 1989 |
Beta-blocker versus diuretic for control of the blood pressure response to stress in hypertensive patients.
Topics: Adult; Amiloride; Atenolol; Chronic Disease; Drug Combinations; Female; Heart Rate; Humans; Hydrochl | 1986 |
33 other studies available for hydrochlorothiazide and Chronic Illness
| Article | Year |
|---|---|
Attributions to new onset catatonic symptoms, late in the course of chronic schizophrenia.
Topics: Amlodipine; Antihypertensive Agents; Antipsychotic Agents; Aripiprazole; Catatonia; Chronic Disease; | 2017 |
Kidney injury molecule 1: in search of biomarkers of chronic tubulointerstitial damage and disease progression.
Topics: Animals; Antihypertensive Agents; Biomarkers; Chronic Disease; Disease Models, Animal; Disease Progr | 2009 |
RAAS blockade in combination with diuretic therapy increases urine excretion, which in turn increases drinking and thus reduces erythropoietin and proteinuria.
Topics: Chronic Disease; Diuretics; Drinking Behavior; Drug Therapy, Combination; Erythropoietin; Hemodiluti | 2010 |
Reversible effects of diuretics added to renin-angiotensin-aldosterone system blockade: impact on interpretation of long-term kidney function outcome.
Topics: Amlodipine; Chronic Disease; Data Interpretation, Statistical; Diuretics; Humans; Hydrochlorothiazid | 2010 |
Effects of losartan, in monotherapy or in association with hydrochlorothiazide, in chronic nephropathy resulting from losartan treatment during lactation.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Blood Pressure; | 2011 |
Effects of an angiotensin 2 receptor blocker plus diuretic combination drug in chronic heart failure complicated by hypertension.
Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; | 2011 |
[Combined low-dose antihypertensive therapy in pregnant women with hypertension and preeclampsia].
Topics: Adult; Antihypertensive Agents; Bisoprolol; Blood Pressure; Chronic Disease; Dose-Response Relations | 2012 |
Renal effects of 26-week administration of olmesartan medoxomil/hydrochlorothiazide in rats.
Topics: Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blo | 2004 |
Management of hypertension in patients with CKD: differences between primary and tertiary care settings.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzy | 2005 |
A thiazide test for the diagnosis of renal tubular hypokalemic disorders.
Topics: Adolescent; Adult; Bartter Syndrome; Child; Chronic Disease; Cohort Studies; Diagnosis, Differential | 2007 |
Refractory paroxysmal ventricular tachycardia.
Topics: Atrial Fibrillation; Chronic Disease; Digoxin; Electrocardiography; Heart Ventricles; Humans; Hydroc | 1967 |
[Characteristics of the action of gemiton, adelfan and dopegit on cerebral circulation in arterial hypertension].
Topics: Aged; Antihypertensive Agents; Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disea | 1984 |
[Changes in the hemodynamic indices of hypertension patients].
Topics: Adult; Aged; Antihypertensive Agents; Chronic Disease; Drug Combinations; Drug Evaluation; Female; H | 1983 |
A non-invasive evaluation of flosequinan on haemodynamics and exercise capacity in chronic congestive heart failure.
Topics: Aged; Amiloride; Cardiac Output; Chronic Disease; Echocardiography; Exercise; Exercise Test; Female; | 1993 |
Hyperkalaemia and diarrhoea in a patient with surreptitious ingestion of potassium sparing diuretics.
Topics: Chronic Disease; Diarrhea; Diuretics; Female; Humans; Hydrochlorothiazide; Hyperaldosteronism; Hyper | 1997 |
Rapid recovery of bone mass in hypercalciuric, osteoporotic men treated with hydrochlorothiazide.
Topics: Aged; Bone Density; Calcium; Chronic Disease; Creatinine; Diuretics; Humans; Hydrochlorothiazide; Mi | 1999 |
Antihypertensive treatment and pregnancy outcome in patients with mild chronic hypertension.
Topics: Adult; Antihypertensive Agents; Chronic Disease; Female; Fetal Growth Retardation; Fetus; Growth; Hu | 1979 |
Pharmacokinetic and clinical studies of a new uricosuric agent - benzbromarone.
Topics: Adult; Aged; Arthritis; Benzbromarone; Benzofurans; Chemical Phenomena; Chemistry; Chronic Disease; | 1976 |
[Certain clinico-biochemical prerequisites for emergency therapy in chronic respiratory insufficiency].
Topics: Acid-Base Imbalance; Adolescent; Adult; Aged; Chronic Disease; Clopamide; Diuretics; Emergencies; Et | 1976 |
Systolic time intervals in chronic hypertension: Alterations and response to treatment.
Topics: Adult; Antihypertensive Agents; Chronic Disease; Female; Heart; Heart Diseases; Heart Function Tests | 1975 |
[The dynamics of the concentration of atrial natriuretic factor depending on changes in the arterial pressure level in patients with arterial hypertension].
Topics: Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Captopril; Chronic Disease; Humans; Hydrochl | 1992 |
[Combination therapy in chronic heart failure. Hemodynamic effects with a calcium antagonist-diuretic combination].
Topics: Adult; Aged; Chronic Disease; Drug Combinations; Heart Failure; Hemodynamics; Humans; Hydrochlorothi | 1991 |
[Nifedipine in the emergency and chronic treatment of arterial hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Chronic Disease; Drug Therapy, Combination; Em | 1987 |
[Arterial hypertension in chronic bronchial obstruction and various problems of its treatment].
Topics: Adult; Asthma; Bronchitis; Chronic Disease; Drug Therapy, Combination; Female; Hemodynamics; Humans; | 1985 |
Thiazide diuretic therapy and chronic photosensitivity.
Topics: Adult; Aged; Chronic Disease; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Photosensitivi | 1985 |
[Treatment of essential hypertension (hypertensive disease) with verapamil and hydrochlorothiazide].
Topics: Adult; Blood Pressure; Chronic Disease; Drug Evaluation; Drug Therapy, Combination; Female; Humans; | 1985 |
Clinical efficacy and safety of long-term diuretic treatment in renal parenchymal hypertension.
Topics: Adult; Aged; Amiloride; Blood Pressure; Cholesterol; Chronic Disease; Diuretics; Drug Therapy, Combi | 1985 |
Diabetes insipidus in a cat.
Topics: Animals; Cat Diseases; Cats; Chronic Disease; Dehydration; Diabetes Insipidus; Hydrochlorothiazide; | 1974 |
[Apparent cure of arterial hypertension].
Topics: Adult; Chronic Disease; Drug Therapy, Combination; Female; Guanethidine; Humans; Hydrochlorothiazide | 1974 |
The lazy respiratory center--or how to recognize a tired horse. Clinical conference in pulmonary disease from Northwestern University-McGaw Medical Center, Chicago.
Topics: Brain Diseases; Chemoreceptor Cells; Chronic Disease; Diagnosis, Differential; Diazepam; Digoxin; Fu | 1974 |
[Treatment of chronic glomerulonephritis and pyelonephritis].
Topics: Anti-Bacterial Agents; Benzimidazoles; Chloroquine; Chronic Disease; Diet Therapy; Glomerulonephriti | 1971 |
Chronic hypernatremia associated with inflammation of the neurohypophysis.
Topics: Aged; Chronic Disease; Dehydration; Female; Humans; Hydrochlorothiazide; Hypernatremia; Inflammation | 1970 |
The nephrotic syndrome in an elderly woman. An unusual association with an unusual response to therapy.
Topics: Aged; Biopsy; Body Weight; Chronic Disease; Diagnosis, Differential; Edema; Female; Humans; Hydrochl | 1969 |