hydrochlorothiazide has been researched along with Carotid Stenosis in 8 studies
Hydrochlorothiazide: A thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
hydrochlorothiazide : A benzothiadiazine that is 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted by a chloro group at position 6 and a sulfonamide at 7. It is diuretic used for the treatment of hypertension and congestive heart failure.
Carotid Stenosis: Narrowing or stricture of any part of the CAROTID ARTERIES, most often due to atherosclerotic plaque formation. Ulcerations may form in atherosclerotic plaques and induce THROMBUS formation. Platelet or cholesterol emboli may arise from stenotic carotid lesions and induce a TRANSIENT ISCHEMIC ATTACK; CEREBROVASCULAR ACCIDENT; or temporary blindness (AMAUROSIS FUGAX). (From Adams et al., Principles of Neurology, 6th ed, pp 822-3)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The purpose of the present exploratory study was to determine whether blood pressure-lowering therapy with the combination of the angiotensin receptor blocker losartan plus hydrochlorothiazide (LPH) worsens brain perfusion in patients with both hypertension and cerebral hemodynamic impairment due to symptomatic chronic major cerebral artery steno-occlusive disease." | 7.78 | Effect of combination therapy with the angiotensin receptor blocker losartan plus hydrochlorothiazide on brain perfusion in patients with both hypertension and cerebral hemodynamic impairment due to symptomatic chronic major cerebral artery steno-occlusiv ( Kobayashi, M; Kuroda, H; Ogasawara, K; Ogawa, A; Saura, H; Suzuki, T; Terasaki, K; Yamashita, T, 2012) |
| "The Plaque Hypertension Lipid-Lowering Italian Study (PHYLLIS) tested whether (1) the angiotensin-converting enzyme (ACE) inhibitor fosinopril (20 mg per day) was more effective on carotid atherosclerosis progression than the diuretic hydrochlorothiazide (25 mg per day), (2) pravastatin (40 mg per day) was more effective than placebo when added to either hydrochlorothiazide or fosinopril, and (3) there were additive effects of ACE inhibitor and lipid-lowering therapies." | 5.11 | Different effects of antihypertensive regimens based on fosinopril or hydrochlorothiazide with or without lipid lowering by pravastatin on progression of asymptomatic carotid atherosclerosis: principal results of PHYLLIS--a randomized double-blind trial. ( Baggio, G; Bond, MG; Crepaldi, G; Gallus, G; Magni, A; Mancia, G; Rubba, P; Sampieri, L; Sperti, G; Veglia, F; Ventura, A; Zanchetti, A, 2004) |
| "This study, ancillary to the International Nifedipine GITS Study: Intervention as a Goal in Hypertension Treatment (INSIGHT), involved nifedipine 30 mg or co-amilozide (hydrochlorothiazide 25 mg and amiloride 2." | 5.09 | Differential effects of nifedipine and co-amilozide on the progression of early carotid wall changes. ( Gariépy, J; Levenson, J; Moyse, D; Simon, A, 2001) |
| " The purpose of the present exploratory study was to determine whether blood pressure-lowering therapy with the combination of the angiotensin receptor blocker losartan plus hydrochlorothiazide (LPH) worsens brain perfusion in patients with both hypertension and cerebral hemodynamic impairment due to symptomatic chronic major cerebral artery steno-occlusive disease." | 3.78 | Effect of combination therapy with the angiotensin receptor blocker losartan plus hydrochlorothiazide on brain perfusion in patients with both hypertension and cerebral hemodynamic impairment due to symptomatic chronic major cerebral artery steno-occlusiv ( Kobayashi, M; Kuroda, H; Ogasawara, K; Ogawa, A; Saura, H; Suzuki, T; Terasaki, K; Yamashita, T, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saura, H | 1 |
| Ogasawara, K | 1 |
| Suzuki, T | 1 |
| Kuroda, H | 1 |
| Yamashita, T | 1 |
| Kobayashi, M | 1 |
| Terasaki, K | 1 |
| Ogawa, A | 1 |
| Zanchetti, A | 1 |
| Crepaldi, G | 1 |
| Bond, MG | 2 |
| Gallus, G | 1 |
| Veglia, F | 1 |
| Mancia, G | 1 |
| Ventura, A | 1 |
| Baggio, G | 1 |
| Sampieri, L | 1 |
| Rubba, P | 1 |
| Sperti, G | 1 |
| Magni, A | 1 |
| Pompeo, F | 1 |
| De Luca, N | 1 |
| Marchegiano, R | 1 |
| Gisonni, P | 1 |
| Iovino, G | 1 |
| D'Auria, F | 1 |
| Del Mastro, L | 1 |
| Simonelli, P | 1 |
| Trimarco, B | 1 |
| Prisant, LM | 1 |
| Zemel, PC | 1 |
| Nichols, FT | 1 |
| Zemel, MB | 1 |
| Sowers, JR | 1 |
| Carr, AA | 1 |
| Thompson, WO | 1 |
| Madren, EM | 1 |
| Semplicini, A | 2 |
| Maresca, A | 2 |
| Simonella, C | 2 |
| Chierichetti, F | 2 |
| Pauletto, P | 2 |
| Meneghetti, G | 1 |
| Ferlin, G | 2 |
| Pessina, AC | 2 |
| Carollo, C | 1 |
| Santipolo, N | 1 |
| Simon, A | 1 |
| Gariépy, J | 1 |
| Moyse, D | 1 |
| Levenson, J | 1 |
6 trials available for hydrochlorothiazide and Carotid Stenosis
| Article | Year |
|---|---|
Different effects of antihypertensive regimens based on fosinopril or hydrochlorothiazide with or without lipid lowering by pravastatin on progression of asymptomatic carotid atherosclerosis: principal results of PHYLLIS--a randomized double-blind trial.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anticholesteremic Agents; Antihypertensive Agents; C | 2004 |
[Effects of antihypertensive treatment on carotid vascular changes].
Topics: Aged; Antihypertensive Agents; Blood Circulation; Blood Pressure; Calcium Channel Blockers; Carotid | 1994 |
Carotid plaque associations among hypertensive patients.
Topics: Aged; Arteriosclerosis; Carotid Stenosis; Female; Georgia; Humans; Hydrochlorothiazide; Hypertension | 1993 |
Cerebral perfusion in hypertensives with carotid artery stenosis: a comparative study of lacidipine and hydrochlorothiazide.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Carotid Stenosis; Cerebrovascular Circulation; Dihydr | 2000 |
Cerebral perfusion in hypertensive patients: effects of lacidipine and hydrochlorothiazide.
Topics: Adult; Aged; Antihypertensive Agents; Carotid Stenosis; Cerebrovascular Circulation; Dihydropyridine | 2000 |
Differential effects of nifedipine and co-amilozide on the progression of early carotid wall changes.
Topics: Aged; Aged, 80 and over; Amiloride; Antihypertensive Agents; Atenolol; Blood Pressure; Carotid Arter | 2001 |
2 other studies available for hydrochlorothiazide and Carotid Stenosis
| Article | Year |
|---|---|
Effect of combination therapy with the angiotensin receptor blocker losartan plus hydrochlorothiazide on brain perfusion in patients with both hypertension and cerebral hemodynamic impairment due to symptomatic chronic major cerebral artery steno-occlusiv
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arterial Occlusive Di | 2012 |
Vascular events during antihypertensive treatment.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Carotid Stenosis; Diuret | 1996 |